| FEDERATED HERMES, INC. | US$3962.2万 | 0.06% |
| RA CAPITAL MANAGEMENT, L.P. | US$2799.9万 | 0.30% |
| BlackRock, Inc. | US$1925.6万 | 0.00% |
| Opaleye Management Inc. | US$1921.5万 | 2.53% |
| Balyasny Asset Management L.P. | US$1539.8万 | 0.02% |
| VANGUARD CAPITAL MANAGEMENT LLC | US$1074.2万 | 0.00% |
| JENNISON ASSOCIATES LLC | US$1048.9万 | 0.01% |
| Siren, L.L.C. | US$1015.1万 | 0.28% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | US$909.4万 | 0.00% |
| BANK OF AMERICA CORP /DE/ | US$906.0万 | 0.00% |
| MORGAN STANLEY | US$838.0万 | 0.00% |
| Integral Health Asset Management, LLC | US$610.0万 | 0.29% |
| GEODE CAPITAL MANAGEMENT, LLC | US$599.3万 | 0.00% |
| UBS Group AG | US$591.1万 | 0.00% |
| STATE STREET CORP | US$540.4万 | 0.00% |
| D. E. Shaw & Co., Inc. | US$538.6万 | 0.00% |
| Affinity Asset Advisors, LLC | US$472.0万 | 0.24% |
| MILLENNIUM MANAGEMENT LLC | US$462.9万 | 0.00% |
| KENNEDY CAPITAL MANAGEMENT LLC | US$377.0万 | 0.08% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | US$331.7万 | 0.00% |
| GREAT POINT PARTNERS LLC | US$290.3万 | 0.67% |
| TWO SIGMA INVESTMENTS, LP | US$253.3万 | 0.00% |
| 22NW, LP | US$250.3万 | 1.72% |
| AQR CAPITAL MANAGEMENT LLC | US$243.0万 | 0.00% |
| Velan Capital Investment Management LP | US$228.8万 | 1.43% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | US$194.7万 | 0.00% |
| NORTHERN TRUST CORP | US$193.0万 | 0.00% |
| Woodline Partners LP | US$186.6万 | 0.01% |
| GOLDMAN SACHS GROUP INC | US$183.7万 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$182.9万 | 0.00% |
| J. Goldman & Co LP | US$178.7万 | 0.05% |
| JANE STREET GROUP, LLC | US$172.4万 | 0.00% |
| DIMENSIONAL FUND ADVISORS LP | US$161.7万 | 0.00% |
| BARCLAYS PLC | US$151.1万 | 0.00% |
| Centiva Capital, LP | US$118.1万 | 0.01% |
| Knott David M Jr | US$112.9万 | 0.67% |
| XTX Topco Ltd | US$89.3万 | 0.02% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | US$67.2万 | 0.00% |
| CITADEL ADVISORS LLC | US$60.4万 | 0.00% |
| Bank of New York Mellon Corp | US$57.9万 | 0.00% |
| RENAISSANCE TECHNOLOGIES LLC | US$48.1万 | 0.00% |
| Virtus Investment Advisers, LLC | US$46.2万 | 0.13% |
| SEI INVESTMENTS CO | US$44.7万 | 0.00% |
| PFM Health Sciences, LP | US$39.3万 | 0.04% |
| Susquehanna Portfolio Strategies, LLC | US$34.9万 | 0.01% |
| HRT FINANCIAL LP | US$31.1万 | 0.00% |
| DLD Asset Management, LP | US$30.4万 | 0.03% |
| Nuveen, LLC | US$29.8万 | 0.00% |
| GSA CAPITAL PARTNERS LLP | US$29.2万 | 0.02% |
| RHUMBLINE ADVISERS | US$27.0万 | 0.00% |
| ExodusPoint Capital Management, LP | US$26.9万 | 0.00% |
| State of Alaska, Department of Revenue | US$26.5万 | 0.00% |
| ALPS ADVISORS INC | US$23.8万 | 0.00% |
| Vanguard Global Advisers, LLC | US$22.6万 | 0.00% |
| AlphaCentric Advisors LLC | US$21.7万 | 0.22% |
| GROUP ONE TRADING LLC | US$20.2万 | 0.00% |
| DEUTSCHE BANK AG\ | US$19.6万 | 0.00% |
| ADAR1 Capital Management, LLC | US$17.9万 | 0.01% |
| PRICE T ROWE ASSOCIATES INC /MD/ | US$17.6万 | 0.00% |
| FMR LLC | US$17.5万 | 0.00% |
| CWM, LLC | US$17.0万 | 0.00% |
| MARSHALL WACE, LLP | US$16.0万 | 0.00% |
| Mariner, LLC | US$14.6万 | 0.00% |
| Russell Investments Group, Ltd. | US$14.1万 | 0.00% |
| Graham Capital Management, L.P. | US$13.4万 | 0.00% |
| MetLife Investment Management, LLC | US$12.8万 | 0.00% |
| Invesco Ltd. | US$12.3万 | 0.00% |
| Rangeley Capital, LLC | US$12.2万 | 0.12% |
| Creative Planning | US$12.0万 | 0.00% |
| HSBC HOLDINGS PLC | US$11.3万 | 0.00% |
| SIMPLEX TRADING, LLC | US$10.7万 | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | US$10.4万 | 0.00% |
| ALLIANCEBERNSTEIN L.P. | US$10.4万 | 0.00% |
| ACADIAN ASSET MANAGEMENT LLC | US$10.1万 | 0.00% |
| Y-Intercept (Hong Kong) Ltd | US$9.0万 | 0.00% |
| JPMORGAN CHASE & CO | US$9.0万 | 0.00% |
| Squarepoint Ops LLC | US$8.9万 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$8.4万 | 0.00% |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | US$8.0万 | 0.00% |
| MML INVESTORS SERVICES, LLC | US$7.5万 | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | US$7.5万 | 0.00% |
| MERCER GLOBAL ADVISORS INC /ADV | US$7.4万 | 0.00% |
| Police & Firemen's Retirement System of New Jersey | US$6.6万 | 0.00% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | US$6.3万 | 0.00% |
| INTECH INVESTMENT MANAGEMENT LLC | US$6.1万 | 0.00% |
| Cerity Partners LLC | US$6.1万 | 0.00% |
| Corient Private Wealth LLC | US$5.6万 | 0.00% |
| Ikarian Capital, LLC | US$5.0万 | 0.00% |
| PANAGORA ASSET MANAGEMENT INC | US$5.0万 | 0.00% |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | US$5.0万 | 0.00% |
| CAPTRUST FINANCIAL ADVISORS | US$4.3万 | 0.00% |
| Brevan Howard Capital Management LP | US$4.3万 | 0.00% |
| HB Wealth Management, LLC | US$4.1万 | 0.00% |
| VOYA INVESTMENT MANAGEMENT LLC | US$3.9万 | 0.00% |
| PRUDENTIAL FINANCIAL INC | US$3.8万 | 0.00% |
| RAYMOND JAMES FINANCIAL INC | US$3.2万 | 0.00% |
| ProShare Advisors LLC | US$3.2万 | 0.00% |
| JEPPSON WEALTH MANAGEMENT, LLC | US$3.1万 | 0.01% |
| Auxano Advisors, LLC | US$3.1万 | 0.01% |
| Legal & General Group Plc | US$2.1万 | 0.00% |
| Ameritas Investment Partners, Inc. | US$2.1万 | 0.00% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | US$1.5万 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | US$1.2万 | 0.00% |
| CITIGROUP INC | US$1.2万 | 0.00% |
| Caitong International Asset Management Co., Ltd | US$1.0万 | 0.00% |
| Tower Research Capital LLC (TRC) | US$9653.0 | 0.00% |
| Pinnacle Wealth Planning Services, Inc. | US$6411.0 | 0.00% |
| Arax Advisory Partners | US$3953.0 | 0.00% |
| Allworth Financial LP | US$3612.0 | 0.00% |
| GAMMA Investing LLC | US$3520.0 | 0.00% |
| MAI Capital Management | US$2623.0 | 0.00% |
| SBI Securities Co., Ltd. | US$2538.0 | 0.00% |
| Sterling Capital Management LLC | US$2355.0 | 0.00% |
| Essential Partners LLC | US$2349.0 | 0.00% |
| Root Financial Partners, LLC | US$2181.0 | 0.00% |
| Farther Finance Advisors, LLC | US$1953.0 | 0.00% |
| IFP Advisors, Inc | US$1650.0 | 0.00% |
| True Wealth Design, LLC | US$1638.0 | 0.00% |
| SIGNATUREFD, LLC | US$1412.0 | 0.00% |
| Quantbot Technologies LP | US$1412.0 | 0.00% |
| Wealth Preservation Advisors, LLC | US$1214.0 | 0.00% |
| ROTHSCHILD INVESTMENT LLC | US$967.0 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | US$555.0 | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | US$543.0 | 0.00% |
| EverSource Wealth Advisors, LLC | US$137.0 | 0.00% |
| SJS Investment Consulting Inc. | US$116.0 | 0.00% |
| MassMutual Private Wealth & Trust, FSB | US$0.0 | 0.00% |