| Sanofi | US$1.1亿 | 31.44% |
| PERCEPTIVE ADVISORS LLC | US$8931.3万 | 1.75% |
| Rubric Capital Management LP | US$6062.0万 | 0.64% |
| JOHNSON & JOHNSON | US$5751.2万 | 8.82% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | US$3464.0万 | 0.05% |
| MILLENNIUM MANAGEMENT LLC | US$3001.3万 | 0.01% |
| BlackRock, Inc. | US$2743.6万 | 0.00% |
| Prosight Management, LP | US$2277.6万 | 3.73% |
| 683 Capital Management, LLC | US$2121.7万 | 1.11% |
| Opaleye Management Inc. | US$1838.7万 | 2.42% |
| MORGAN STANLEY | US$1376.9万 | 0.00% |
| Knoll Capital Management, LLC | US$1082.5万 | 6.01% |
| KENNEDY CAPITAL MANAGEMENT LLC | US$743.4万 | 0.16% |
| STATE STREET CORP | US$652.4万 | 0.00% |
| Logos Global Management LP | US$606.2万 | 0.30% |
| Erste Asset Management GmbH | US$582.2万 | 0.05% |
| GEODE CAPITAL MANAGEMENT, LLC | US$506.5万 | 0.00% |
| Long Focus Capital Management, LLC | US$454.4万 | 0.12% |
| GOLDMAN SACHS GROUP INC | US$382.3万 | 0.00% |
| D. E. Shaw & Co., Inc. | US$368.3万 | 0.00% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | US$344.0万 | 0.00% |
| Hennion & Walsh Asset Management, Inc. | US$307.2万 | 0.10% |
| UBS Group AG | US$262.6万 | 0.00% |
| Woodline Partners LP | US$260.1万 | 0.01% |
| NORTHERN TRUST CORP | US$235.4万 | 0.00% |
| BANK OF AMERICA CORP /DE/ | US$212.1万 | 0.00% |
| Privium Fund Management B.V. | US$183.7万 | 0.38% |
| J. Goldman & Co LP | US$178.6万 | 0.05% |
| Jefferies Financial Group Inc. | US$145.0万 | 0.01% |
| JANE STREET GROUP, LLC | US$118.8万 | 0.00% |
| Nuveen, LLC | US$114.7万 | 0.00% |
| WELLINGTON MANAGEMENT GROUP LLP | US$109.4万 | 0.00% |
| BLAIR WILLIAM & CO/IL | US$108.6万 | 0.00% |
| CITADEL ADVISORS LLC | US$100.5万 | 0.00% |
| AQR CAPITAL MANAGEMENT LLC | US$96.1万 | 0.00% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | US$86.8万 | 0.00% |
| Bank of New York Mellon Corp | US$86.7万 | 0.00% |
| SEI INVESTMENTS CO | US$86.3万 | 0.00% |
| Trexquant Investment LP | US$84.5万 | 0.01% |
| Russell Investments Group, Ltd. | US$84.1万 | 0.00% |
| Invesco Ltd. | US$81.8万 | 0.00% |
| PLATINUM INVESTMENT MANAGEMENT LTD | US$81.3万 | 0.21% |
| Point72 Asset Management, L.P. | US$61.4万 | 0.00% |
| DAVENPORT & Co LLC | US$59.9万 | 0.00% |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | US$59.1万 | 0.01% |
| Fort Sheridan Advisors LLC | US$57.9万 | 0.07% |
| Quantinno Capital Management LP | US$48.8万 | 0.00% |
| Jump Financial, LLC | US$48.7万 | 0.01% |
| RHUMBLINE ADVISERS | US$48.3万 | 0.00% |
| RAYMOND JAMES FINANCIAL INC | US$46.6万 | 0.00% |
| AlphaCentric Advisors LLC | US$46.5万 | 0.46% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | US$45.7万 | 0.00% |
| ALLIANCEBERNSTEIN L.P. | US$43.4万 | 0.00% |
| BROWN ADVISORY INC | US$43.3万 | 0.00% |
| XTX Topco Ltd | US$37.5万 | 0.01% |
| HSBC HOLDINGS PLC | US$33.8万 | 0.00% |
| BARCLAYS PLC | US$33.0万 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$29.2万 | 0.00% |
| LETKO, BROSSEAU & ASSOCIATES INC | US$27.7万 | 0.00% |
| EntryPoint Capital, LLC | US$27.7万 | 0.08% |
| PRICE T ROWE ASSOCIATES INC /MD/ | US$27.3万 | 0.00% |
| Virtus Investment Advisers, LLC | US$26.5万 | 0.07% |
| DEUTSCHE BANK AG\ | US$26.2万 | 0.00% |
| Engineers Gate Manager LP | US$23.2万 | 0.00% |
| Beacon Pointe Advisors, LLC | US$23.2万 | 0.00% |
| CreativeOne Wealth, LLC | US$22.9万 | 0.01% |
| HRT FINANCIAL LP | US$21.1万 | 0.00% |
| SkyView Investment Advisors, LLC | US$20.8万 | 0.03% |
| JPMORGAN CHASE & CO | US$19.7万 | 0.00% |
| MetLife Investment Management, LLC | US$19.7万 | 0.00% |
| Voleon Capital Management LP | US$19.4万 | 0.00% |
| Mitsubishi UFJ Asset Management Co., Ltd. | US$19.1万 | 0.00% |
| ExodusPoint Capital Management, LP | US$18.9万 | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | US$18.6万 | 0.00% |
| Squarepoint Ops LLC | US$16.1万 | 0.00% |
| CIBC Bancorp USA Inc. | US$15.0万 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$14.4万 | 0.00% |
| Creative Planning | US$13.4万 | 0.00% |
| Perigon Wealth Management, LLC | US$13.1万 | 0.00% |
| China Universal Asset Management Co., Ltd. | US$12.4万 | 0.01% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | US$11.8万 | 0.00% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | US$11.4万 | 0.00% |
| GSA CAPITAL PARTNERS LLP | US$10.8万 | 0.01% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | US$10.6万 | 0.00% |
| BANK OF NOVA SCOTIA | US$10.5万 | 0.00% |
| Police & Firemen's Retirement System of New Jersey | US$10.1万 | 0.00% |
| INTECH INVESTMENT MANAGEMENT LLC | US$9.0万 | 0.00% |
| STATE OF WISCONSIN INVESTMENT BOARD | US$9.0万 | 0.00% |
| ALGERT GLOBAL LLC | US$8.9万 | 0.00% |
| Hudson Bay Capital Management LP | US$8.8万 | 0.00% |
| ProShare Advisors LLC | US$8.8万 | 0.00% |
| ROYAL BANK OF CANADA | US$8.4万 | 0.00% |
| CWM, LLC | US$6.7万 | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | US$6.3万 | 0.00% |
| Rockefeller Capital Management L.P. | US$5.8万 | 0.00% |
| FMR LLC | US$5.0万 | 0.00% |
| CITIGROUP INC | US$4.7万 | 0.00% |
| Mirae Asset Global Investments Co., Ltd. | US$3.6万 | 0.00% |
| State of Alaska, Department of Revenue | US$3.4万 | 0.00% |
| Legal & General Group Plc | US$3.3万 | 0.00% |
| Ameritas Investment Partners, Inc. | US$3.0万 | 0.00% |
| STRS OHIO | US$2.4万 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | US$2.1万 | 0.00% |
| Versant Capital Management, Inc | US$2.0万 | 0.00% |
| Tower Research Capital LLC (TRC) | US$1.9万 | 0.00% |
| GF FUND MANAGEMENT CO. LTD. | US$1.6万 | 0.00% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | US$1.3万 | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | US$9674.9 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | US$8920.0 | 0.00% |
| Aquatic Capital Management LLC | US$8192.0 | 0.00% |
| Atlantic Union Bankshares Corp | US$6928.0 | 0.00% |
| Sterling Capital Management LLC | US$5231.0 | 0.00% |
| Farther Finance Advisors, LLC | US$3891.0 | 0.00% |
| Optiver Holding B.V. | US$3585.0 | 0.00% |
| GAMMA Investing LLC | US$3343.0 | 0.00% |
| Parallel Advisors, LLC | US$2425.0 | 0.00% |
| Essential Partners LLC | US$1819.0 | 0.00% |
| ROTHSCHILD INVESTMENT LLC | US$1559.0 | 0.00% |
| OSAIC HOLDINGS, INC. | US$1403.0 | 0.00% |
| SBI Securities Co., Ltd. | US$883.0 | 0.00% |
| Parkside Financial Bank & Trust | US$650.0 | 0.00% |
| Torren Management, LLC | US$606.0 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | US$450.0 | 0.00% |
| Arax Advisory Partners | US$372.0 | 0.00% |
| Allworth Financial LP | US$304.0 | 0.00% |
| EverSource Wealth Advisors, LLC | US$287.0 | 0.00% |
| Root Financial Partners, LLC | US$286.0 | 0.00% |
| True Wealth Design, LLC | US$226.0 | 0.00% |
| US BANCORP \DE\ | US$147.0 | 0.00% |
| IFP Advisors, Inc | US$139.0 | 0.00% |
| Larson Financial Group LLC | US$87.0 | 0.00% |
| MAI Capital Management | US$26.0 | 0.00% |
| Caitong International Asset Management Co., Ltd | US$9.0 | 0.00% |