| SUVRETTA CAPITAL MANAGEMENT, LLC | US$5032.4萬 | 1.29% |
| RA CAPITAL MANAGEMENT, L.P. | US$4643.4萬 | 0.49% |
| BlackRock, Inc. | US$4134.6萬 | 0.00% |
| TCG Crossover Management, LLC | US$4026.8萬 | 1.15% |
| BRAIDWELL LP | US$2404.5萬 | 0.80% |
| Nantahala Capital Management, LLC | US$2339.4萬 | 0.86% |
| VANGUARD CAPITAL MANAGEMENT LLC | US$2065.5萬 | 0.00% |
| Siren, L.L.C. | US$1802.5萬 | 0.50% |
| First Turn Management, LLC | US$1730.4萬 | 1.93% |
| Aberdeen Group plc | US$1696.6萬 | 0.03% |
| Balyasny Asset Management L.P. | US$1672.0萬 | 0.02% |
| Point72 Asset Management, L.P. | US$1591.4萬 | 0.02% |
| GSK plc | US$1369.6萬 | 2.29% |
| Jones Hill Capital LP | US$1359.1萬 | 2.91% |
| D. E. Shaw & Co., Inc. | US$1245.1萬 | 0.01% |
| STATE STREET CORP | US$1188.7萬 | 0.00% |
| GEODE CAPITAL MANAGEMENT, LLC | US$1140.4萬 | 0.00% |
| CITADEL ADVISORS LLC | US$1036.0萬 | 0.00% |
| Alyeska Investment Group, L.P. | US$1018.9萬 | 0.03% |
| Assenagon Asset Management S.A. | US$915.7萬 | 0.01% |
| DIMENSIONAL FUND ADVISORS LP | US$866.3萬 | 0.00% |
| Vestal Point Capital, LP | US$843.7萬 | 0.24% |
| Ikarian Capital, LLC | US$804.7萬 | 0.65% |
| Qube Research & Technologies Ltd | US$747.6萬 | 0.01% |
| Connor, Clark & Lunn Investment Management Ltd. | US$565.0萬 | 0.01% |
| ACADIAN ASSET MANAGEMENT LLC | US$557.1萬 | 0.01% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | US$459.7萬 | 0.00% |
| GOLDMAN SACHS GROUP INC | US$438.7萬 | 0.00% |
| AQR CAPITAL MANAGEMENT LLC | US$416.6萬 | 0.00% |
| NORTHERN TRUST CORP | US$362.8萬 | 0.00% |
| Trexquant Investment LP | US$347.9萬 | 0.02% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | US$327.4萬 | 0.00% |
| SILVERARC CAPITAL MANAGEMENT, LLC | US$322.1萬 | 0.33% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | US$306.8萬 | 0.00% |
| Jump Financial, LLC | US$283.6萬 | 0.04% |
| MILLENNIUM MANAGEMENT LLC | US$273.4萬 | 0.00% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | US$257.0萬 | 0.00% |
| JANE STREET GROUP, LLC | US$254.4萬 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$253.0萬 | 0.00% |
| UBS Group AG | US$241.7萬 | 0.00% |
| BOOTHBAY FUND MANAGEMENT, LLC | US$233.2萬 | 0.03% |
| BESSEMER GROUP INC | US$220.1萬 | 0.00% |
| PANAGORA ASSET MANAGEMENT INC | US$186.8萬 | 0.01% |
| DAFNA Capital Management LLC | US$157.2萬 | 0.36% |
| Squarepoint Ops LLC | US$134.9萬 | 0.00% |
| MORGAN STANLEY | US$132.9萬 | 0.00% |
| AMERICAN CENTURY COMPANIES INC | US$119.8萬 | 0.00% |
| STATE OF WISCONSIN INVESTMENT BOARD | US$118.5萬 | 0.00% |
| Y-Intercept (Hong Kong) Ltd | US$117.6萬 | 0.02% |
| Bank of New York Mellon Corp | US$115.0萬 | 0.00% |
| TWO SIGMA INVESTMENTS, LP | US$106.6萬 | 0.00% |
| GSA CAPITAL PARTNERS LLP | US$104.8萬 | 0.07% |
| Fiduciary Trust Co | US$104.7萬 | 0.01% |
| ADAR1 Capital Management, LLC | US$100.1萬 | 0.06% |
| Nuveen, LLC | US$99.4萬 | 0.00% |
| BANK OF AMERICA CORP /DE/ | US$97.1萬 | 0.00% |
| Engineers Gate Manager LP | US$96.7萬 | 0.01% |
| WELLINGTON MANAGEMENT GROUP LLP | US$91.0萬 | 0.00% |
| Simplify Asset Management Inc. | US$89.0萬 | 0.01% |
| Invesco Ltd. | US$85.2萬 | 0.00% |
| BARCLAYS PLC | US$67.8萬 | 0.00% |
| PRICE T ROWE ASSOCIATES INC /MD/ | US$61.5萬 | 0.00% |
| Russell Investments Group, Ltd. | US$60.7萬 | 0.00% |
| XTX Topco Ltd | US$54.9萬 | 0.01% |
| RBF Capital, LLC | US$53.7萬 | 0.03% |
| Atom Investors LP | US$53.0萬 | 0.04% |
| RHUMBLINE ADVISERS | US$50.8萬 | 0.00% |
| Creative Planning | US$49.2萬 | 0.00% |
| FMR LLC | US$46.8萬 | 0.00% |
| HSBC HOLDINGS PLC | US$44.2萬 | 0.00% |
| FRANKLIN RESOURCES INC | US$41.9萬 | 0.00% |
| GROUP ONE TRADING LLC | US$41.2萬 | 0.00% |
| ALLIANCEBERNSTEIN L.P. | US$39.1萬 | 0.00% |
| Burkehill Global Management, LP | US$38.4萬 | 0.02% |
| STRS OHIO | US$37.8萬 | 0.00% |
| DEUTSCHE BANK AG\ | US$37.5萬 | 0.00% |
| Man Group plc | US$35.4萬 | 0.00% |
| EntryPoint Capital, LLC | US$34.7萬 | 0.10% |
| Graham Capital Management, L.P. | US$32.8萬 | 0.01% |
| Marex Group plc | US$32.2萬 | 0.00% |
| SIMPLEX TRADING, LLC | US$32.2萬 | 0.00% |
| COMMONWEALTH EQUITY SERVICES, LLC | US$30.9萬 | 0.00% |
| BIT Capital GmbH | US$30.7萬 | 0.01% |
| Matisse Capital | US$30.4萬 | 0.13% |
| Brevan Howard Capital Management LP | US$30.3萬 | 0.00% |
| Vanguard Global Advisers, LLC | US$29.5萬 | 0.00% |
| Seven Fleet Capital Management LP | US$29.2萬 | 0.09% |
| MetLife Investment Management, LLC | US$25.4萬 | 0.00% |
| ALGERT GLOBAL LLC | US$25.3萬 | 0.00% |
| Woodline Partners LP | US$23.6萬 | 0.00% |
| COUNTRY TRUST BANK | US$23.0萬 | 0.00% |
| LMR Partners LLP | US$23.0萬 | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | US$21.5萬 | 0.00% |
| Pale Fire Capital SE | US$20.0萬 | 0.02% |
| Quantinno Capital Management LP | US$19.7萬 | 0.00% |
| JPMORGAN CHASE & CO | US$19.6萬 | 0.00% |
| CITIGROUP INC | US$18.0萬 | 0.00% |
| Mariner, LLC | US$17.8萬 | 0.00% |
| ExodusPoint Capital Management, LP | US$17.8萬 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$17.3萬 | 0.00% |
| AXQ CAPITAL, LP | US$16.9萬 | 0.02% |
| Virtus Investment Advisers, LLC | US$16.1萬 | 0.04% |
| Susquehanna Portfolio Strategies, LLC | US$14.8萬 | 0.00% |
| Police & Firemen's Retirement System of New Jersey | US$14.2萬 | 0.00% |
| CANADA PENSION PLAN INVESTMENT BOARD | US$14.1萬 | 0.00% |
| Legal & General Group Plc | US$13.6萬 | 0.00% |
| Westshore Wealth, LLC | US$13.0萬 | 0.05% |
| DRW Securities, LLC | US$12.6萬 | 0.00% |
| Vanguard Personalized Indexing Management, LLC | US$12.4萬 | 0.00% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | US$12.4萬 | 0.00% |
| PROFUND ADVISORS LLC | US$11.9萬 | 0.00% |
| RENAISSANCE TECHNOLOGIES LLC | US$10.4萬 | 0.00% |
| INTECH INVESTMENT MANAGEMENT LLC | US$10.2萬 | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | US$10.0萬 | 0.00% |
| SG Americas Securities, LLC | US$9.3萬 | 0.00% |
| CWM, LLC | US$9.3萬 | 0.00% |
| China Universal Asset Management Co., Ltd. | US$9.1萬 | 0.01% |
| BAILARD, INC. | US$9.0萬 | 0.00% |
| ProShare Advisors LLC | US$8.9萬 | 0.00% |
| MERCER GLOBAL ADVISORS INC /ADV | US$8.3萬 | 0.00% |
| Entropy Technologies, LP | US$8.3萬 | 0.00% |
| VOYA INVESTMENT MANAGEMENT LLC | US$7.7萬 | 0.00% |
| ASSETMARK, INC | US$5.8萬 | 0.00% |
| SUMMIT SECURITIES GROUP LLC | US$5.3萬 | 0.01% |
| Tower Research Capital LLC (TRC) | US$5.0萬 | 0.00% |
| Ameritas Investment Partners, Inc. | US$3.8萬 | 0.00% |
| Mirae Asset Global Investments Co., Ltd. | US$2.7萬 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | US$2.5萬 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | US$2.4萬 | 0.00% |
| ROYAL BANK OF CANADA | US$2.1萬 | 0.00% |
| Farther Finance Advisors, LLC | US$1.8萬 | 0.00% |
| MAI Capital Management | US$1.4萬 | 0.00% |
| Sterling Capital Management LLC | US$1.4萬 | 0.00% |
| State of Wyoming | US$1.4萬 | 0.00% |
| GF FUND MANAGEMENT CO. LTD. | US$9235.0 | 0.00% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | US$9066.0 | 0.00% |
| Rockefeller Capital Management L.P. | US$8583.0 | 0.00% |
| IFP Advisors, Inc | US$7578.0 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | US$6788.0 | 0.00% |
| Allworth Financial LP | US$6620.0 | 0.00% |
| Versant Capital Management, Inc | US$6581.0 | 0.00% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | US$5929.0 | 0.00% |
| MassMutual Private Wealth & Trust, FSB | US$4456.0 | 0.00% |
| Optiver Holding B.V. | US$4065.0 | 0.00% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | US$3620.0 | 0.00% |
| NATIONAL BANK OF CANADA /FI/ | US$3232.0 | 0.00% |
| EverSource Wealth Advisors, LLC | US$3137.0 | 0.00% |
| Larson Financial Group LLC | US$3122.0 | 0.00% |
| FEDERATED HERMES, INC. | US$2516.0 | 0.00% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | US$2263.0 | 0.00% |