持有 VRTX 的機構名單（共 1689 家）

目前共有 1689 家機構持有 VRTX，以下依持股市值由高至低排序。

主要持有機構	總市值	平均佔比
Capital World Investors	US$113.3億	1.55%
BlackRock, Inc.	US$107.0億	0.19%
Capital Research Global Investors	US$94.3億	1.46%
VANGUARD CAPITAL MANAGEMENT LLC	US$73.7億	0.18%
STATE STREET CORP	US$52.4億	0.18%
JPMORGAN CHASE & CO	US$32.0億	0.20%
GEODE CAPITAL MANAGEMENT, LLC	US$27.3億	0.17%
VANGUARD PORTFOLIO MANAGEMENT LLC	US$23.0億	0.12%
Capital International Investors	US$22.9億	0.54%
LOOMIS SAYLES & CO L P	US$17.9億	2.41%
ALLIANCEBERNSTEIN L.P.	US$17.7億	0.57%
WELLINGTON MANAGEMENT GROUP LLP	US$14.3億	0.27%
MORGAN STANLEY	US$14.2億	0.09%
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	US$13.7億	0.28%
BANK OF AMERICA CORP /DE/	US$12.9億	0.09%
JENNISON ASSOCIATES LLC	US$12.2億	0.84%
Clearbridge Investments, LLC	US$12.1億	1.05%
AMERIPRISE FINANCIAL INC	US$11.8億	0.27%
NORTHERN TRUST CORP	US$11.5億	0.15%
Invesco Ltd.	US$11.4億	0.18%
GOLDMAN SACHS GROUP INC	US$11.0億	0.13%
JANUS HENDERSON GROUP PLC	US$9.5億	0.45%
FMR LLC	US$9.0億	0.05%
Legal & General Group Plc	US$8.7億	0.20%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	US$8.6億	0.13%
VICTORY CAPITAL MANAGEMENT INC	US$8.4億	0.54%
PRICE T ROWE ASSOCIATES INC /MD/	US$7.9億	0.09%
Bank of New York Mellon Corp	US$7.1億	0.13%
DEUTSCHE BANK AG\	US$6.9億	0.23%
Amundi	US$6.6億	0.18%
VANGUARD FIDUCIARY TRUST CO	US$6.5億	0.17%
SUSQUEHANNA INTERNATIONAL GROUP, LLP	US$5.7億	0.06%
WCM INVESTMENT MANAGEMENT, LLC	US$5.0億	1.13%
ROYAL BANK OF CANADA	US$5.0億	0.09%
Nuveen, LLC	US$4.8億	0.13%
DIMENSIONAL FUND ADVISORS LP	US$4.4億	0.09%
EDGEWOOD MANAGEMENT LLC	US$4.0億	2.61%
BNP PARIBAS ASSET MANAGEMENT Holding S.A.	US$3.8億	0.44%
AMERICAN CENTURY COMPANIES INC	US$3.6億	0.19%
WELLS FARGO & COMPANY/MN	US$3.3億	0.06%
Swiss National Bank	US$3.3億	0.19%
UBS Group AG	US$3.3億	0.05%
CITIGROUP INC	US$3.3億	0.14%
BARCLAYS PLC	US$3.1億	0.07%
Bellevue Group AG	US$3.0億	7.25%
HSBC HOLDINGS PLC	US$3.0億	0.16%
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	US$2.9億	0.15%
CITADEL ADVISORS LLC	US$2.8億	0.05%
Sumitomo Mitsui Trust Group, Inc.	US$2.7億	0.18%
Mitsubishi UFJ Asset Management Co., Ltd.	US$2.7億	0.18%
Vanguard Global Advisers, LLC	US$2.5億	0.13%
NATIXIS ADVISORS, LLC	US$2.5億	0.34%
MANUFACTURERS LIFE INSURANCE COMPANY, THE	US$2.5億	0.21%
NEUBERGER BERMAN GROUP LLC	US$2.5億	0.19%
FRANKLIN RESOURCES INC	US$2.5億	0.06%
Assenagon Asset Management S.A.	US$2.4億	0.36%
National Pension Service	US$2.4億	0.18%
VOYA INVESTMENT MANAGEMENT LLC	US$2.3億	0.24%
DekaBank Deutsche Girozentrale	US$2.3億	0.38%
B. Metzler seel. Sohn & Co. AG	US$2.3億	2.12%
ENVESTNET ASSET MANAGEMENT INC	US$2.2億	0.06%
California Public Employees Retirement System	US$2.2億	0.14%
RAYMOND JAMES FINANCIAL INC	US$2.0億	0.06%
VANGUARD ASSET MANAGEMENT, Ltd	US$2.0億	0.17%
Life Cycle Investment Partners Ltd	US$2.0億	1.25%
PRINCIPAL FINANCIAL GROUP INC	US$1.9億	0.10%
RHUMBLINE ADVISERS	US$1.9億	0.16%
RENAISSANCE TECHNOLOGIES LLC	US$1.9億	0.29%
JANE STREET GROUP, LLC	US$1.9億	0.02%
Chevy Chase Trust Holdings, LLC	US$1.8億	0.52%
Robeco Institutional Asset Management B.V.	US$1.8億	0.26%
BANK OF MONTREAL /CAN/	US$1.7億	0.07%
TWO SIGMA INVESTMENTS, LP	US$1.7億	0.14%
Zurcher Kantonalbank (Zurich Cantonalbank)	US$1.7億	0.37%
ProShare Advisors LLC	US$1.7億	0.25%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	US$1.7億	0.18%
Russell Investments Group, Ltd.	US$1.6億	0.18%
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	US$1.6億	0.14%
Universal- Beteiligungs- und Servicegesellschaft mbH	US$1.5億	0.26%
Pictet Asset Management Holding SA	US$1.5億	0.16%
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	US$1.5億	0.05%
MARSHALL WACE, LLP	US$1.4億	0.14%
Bank Julius Baer & Co. Ltd, Zurich	US$1.4億	0.43%
Harding Loevner LP	US$1.4億	1.44%
AMF Tjanstepension AB	US$1.4億	0.93%
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	US$1.4億	0.55%
FIRST TRUST ADVISORS LP	US$1.4億	0.10%
Cerity Partners LLC	US$1.3億	0.19%
NEW YORK STATE COMMON RETIREMENT FUND	US$1.3億	0.18%
NATIONAL BANK OF CANADA /FI/	US$1.2億	0.12%
Swedbank AB	US$1.2億	0.13%
LPL Financial LLC	US$1.2億	0.03%
ROYAL LONDON ASSET MANAGEMENT LTD	US$1.1億	0.24%
ADAGE CAPITAL PARTNERS GP, L.L.C.	US$1.1億	0.17%
Connor, Clark & Lunn Investment Management Ltd.	US$1.1億	0.26%
D. E. Shaw & Co., Inc.	US$1.1億	0.07%
Man Group plc	US$1.1億	0.19%
Aberdeen Group plc	US$1.0億	0.17%
Candriam S.C.A.	US$1.0億	0.53%
TD Asset Management Inc	US$1.0億	0.08%
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	US$1.0億	0.19%
AVIVA PLC	US$9933.4萬	0.17%
Handelsbanken Fonder AB	US$9861.7萬	0.33%
MANNING & NAPIER ADVISORS LLC	US$9850.2萬	1.39%
Welch & Forbes LLC	US$9809.1萬	1.27%
Ensign Peak Advisors, Inc	US$9608.0萬	0.18%
LAZARD ASSET MANAGEMENT LLC	US$9517.2萬	0.16%
NEW YORK STATE TEACHERS RETIREMENT SYSTEM	US$9437.0萬	0.19%
DAVENPORT & Co LLC	US$9366.2萬	0.51%
CAPITAL INTERNATIONAL SARL	US$9327.4萬	1.53%
AGF MANAGEMENT LTD	US$8993.4萬	0.40%
Korea Investment CORP	US$8983.0萬	0.19%
BAILLIE GIFFORD & CO	US$8904.9萬	0.09%
JONES FINANCIAL COMPANIES LLLP	US$8785.5萬	0.04%
CANADA LIFE ASSURANCE Co	US$8605.9萬	0.15%
CANADA PENSION PLAN INVESTMENT BOARD	US$8486.5萬	0.05%
Mirae Asset Global Investments Co., Ltd.	US$8397.8萬	0.03%
MILLENNIUM MANAGEMENT LLC	US$8141.5萬	0.03%
NEOS Investment Management LLC	US$7773.7萬	0.39%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	US$7657.4萬	0.10%
AQR CAPITAL MANAGEMENT LLC	US$7603.2萬	0.03%
Mitsubishi UFJ Trust & Banking Corp	US$7452.9萬	0.18%
LORD, ABBETT & CO. LLC	US$7435.3萬	0.24%
APG Asset Management N.V.	US$7417.2萬	0.24%
GROUPAMA ASSET MANAGMENT	US$7408.0萬	1.08%
SCHRODER INVESTMENT MANAGEMENT GROUP	US$7263.3萬	0.06%
Capital International, Inc./CA/	US$7221.6萬	0.56%
IMC-Chicago, LLC	US$7208.6萬	0.01%
STIFEL FINANCIAL CORP	US$7191.7萬	0.07%
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	US$6987.6萬	0.12%
DANSKE BANK A/S	US$6832.3萬	0.16%
Birch Hill Investment Advisors LLC	US$6733.6萬	3.02%
FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND	US$6696.4萬	0.37%
Rockefeller Capital Management L.P.	US$6682.7萬	0.12%
Provident Investment Management, Inc.	US$6591.8萬	6.55%
VAN ECK ASSOCIATES CORP	US$6524.7萬	0.05%
Asset Management One Co., Ltd.	US$6338.6萬	0.19%
SEB Asset Management AB	US$6294.0萬	0.27%
STATE OF WISCONSIN INVESTMENT BOARD	US$6097.4萬	0.14%
BOWEN HANES & CO INC	US$6046.1萬	1.47%
PFA Pension, Forsikringsaktieselskab	US$6028.1萬	0.18%
Woodline Partners LP	US$6026.2萬	0.23%
SEI INVESTMENTS CO	US$5949.4萬	0.05%
Mariner, LLC	US$5875.5萬	0.07%
PRUDENTIAL FINANCIAL INC	US$5874.7萬	0.07%
Focus Partners Wealth	US$5867.4萬	0.07%
Tri Locum Partners LP	US$5774.4萬	8.10%
KBC Group NV	US$5680.4萬	0.14%
Quantinno Capital Management LP	US$5653.4萬	0.09%
Vanguard Investments Australia, Ltd.	US$5638.1萬	0.16%