| Flagship Pioneering, LLC | US$7.8亿 | 67.44% |
| FMR LLC | US$5271.9万 | 0.00% |
| Capital World Investors | US$5005.2万 | 0.01% |
| BRAIDWELL LP | US$4491.2万 | 1.50% |
| JPMORGAN CHASE & CO | US$3392.3万 | 0.00% |
| PRICE T ROWE ASSOCIATES INC /MD/ | US$2637.1万 | 0.00% |
| ARCH Venture Management, LLC | US$2430.5万 | 3.59% |
| HarbourVest Partners LLC | US$2152.8万 | 21.33% |
| BAKER BROS. ADVISORS LP | US$1779.5万 | 0.10% |
| HARVARD MANAGEMENT CO INC | US$1388.9万 | 0.76% |
| NVIDIA CORP | US$1041.7万 | 0.06% |
| Siren, L.L.C. | US$920.1万 | 0.26% |
| Davern Capital Partners, LP | US$739.8万 | 2.03% |
| Alyeska Investment Group, L.P. | US$625.0万 | 0.02% |
| ARK Investment Management LLC | US$623.0万 | 0.05% |
| MILLENNIUM MANAGEMENT LLC | US$471.1万 | 0.00% |
| UBS Group AG | US$445.9万 | 0.00% |
| Affinity Asset Advisors, LLC | US$437.5万 | 0.23% |
| MORGAN STANLEY | US$421.6万 | 0.00% |
| CenterBook Partners LP | US$333.5万 | 0.18% |
| SPHERA FUNDS MANAGEMENT LTD. | US$231.3万 | 0.37% |
| GOLDMAN SACHS GROUP INC | US$213.4万 | 0.00% |
| VANGUARD CAPITAL MANAGEMENT LLC | US$164.1万 | 0.00% |
| SEVEN GRAND MANAGERS, LLC | US$156.3万 | 0.10% |
| JANE STREET GROUP, LLC | US$154.2万 | 0.00% |
| GEODE CAPITAL MANAGEMENT, LLC | US$147.8万 | 0.00% |
| LMR Partners LLP | US$125.0万 | 0.00% |
| SILVERARC CAPITAL MANAGEMENT, LLC | US$125.0万 | 0.13% |
| D. E. Shaw & Co., Inc. | US$118.8万 | 0.00% |
| AMERIPRISE FINANCIAL INC | US$109.2万 | 0.00% |
| Balyasny Asset Management L.P. | US$99.4万 | 0.00% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | US$92.9万 | 0.00% |
| BARCLAYS PLC | US$88.6万 | 0.00% |
| HRT FINANCIAL LP | US$73.4万 | 0.00% |
| Qube Research & Technologies Ltd | US$62.8万 | 0.00% |
| TD Asset Management Inc | US$53.6万 | 0.00% |
| Sumitomo Mitsui Trust Group, Inc. | US$50.4万 | 0.00% |
| Amova Asset Management Americas, Inc. | US$49.9万 | 0.01% |
| Squarepoint Ops LLC | US$46.5万 | 0.00% |
| BANK OF AMERICA CORP /DE/ | US$42.7万 | 0.00% |
| FEDERATED HERMES, INC. | US$37.5万 | 0.00% |
| TUDOR INVESTMENT CORP ET AL | US$29.8万 | 0.00% |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | US$24.0万 | 0.02% |
| Y-Intercept (Hong Kong) Ltd | US$23.0万 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$21.8万 | 0.00% |
| Hudson Bay Capital Management LP | US$20.8万 | 0.00% |
| Brevan Howard Capital Management LP | US$15.7万 | 0.00% |
| Diametric Capital, LP | US$13.1万 | 0.03% |
| Parallel Advisors, LLC | US$6.9万 | 0.00% |
| ALBION FINANCIAL GROUP /UT | US$6.1万 | 0.00% |
| FNY Investment Advisers, LLC | US$3.7万 | 0.02% |
| CITIGROUP INC | US$2.8万 | 0.00% |
| Vanguard Global Advisers, LLC | US$1.5万 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$1.5万 | 0.00% |
| ROYAL BANK OF CANADA | US$3000.0 | 0.00% |
| Avion Wealth | US$1000.0 | 0.00% |
| Tower Research Capital LLC (TRC) | US$12.0 | 0.00% |