| Lynx1 Capital Management LP | US$1741.4萬 | 2.75% |
| NEA Management Company, LLC | US$1469.2萬 | 0.84% |
| Atlas Venture Life Science Advisors, LLC | US$1287.3萬 | 1.63% |
| Balyasny Asset Management L.P. | US$1177.3萬 | 0.02% |
| Venrock Adviser, LLC | US$1142.8萬 | 0.43% |
| Affinity Asset Advisors, LLC | US$800.2萬 | 0.41% |
| Nantahala Capital Management, LLC | US$747.2萬 | 0.28% |
| ADAR1 Capital Management, LLC | US$611.3萬 | 0.36% |
| BlackRock, Inc. | US$520.7萬 | 0.00% |
| Driehaus Capital Management LLC | US$509.5萬 | 0.04% |
| TCG Crossover Management, LLC | US$471.3萬 | 0.13% |
| Siren, L.L.C. | US$393.6萬 | 0.11% |
| VANGUARD CAPITAL MANAGEMENT LLC | US$352.0萬 | 0.00% |
| 72 Investment Holdings, LLC | US$313.4萬 | 6.32% |
| CITADEL ADVISORS LLC | US$304.6萬 | 0.00% |
| AQR CAPITAL MANAGEMENT LLC | US$303.1萬 | 0.00% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | US$258.5萬 | 0.00% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | US$231.0萬 | 0.00% |
| GEODE CAPITAL MANAGEMENT, LLC | US$196.6萬 | 0.00% |
| TWO SIGMA INVESTMENTS, LP | US$187.3萬 | 0.00% |
| JANE STREET GROUP, LLC | US$179.4萬 | 0.00% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | US$168.2萬 | 0.00% |
| STATE STREET CORP | US$158.9萬 | 0.00% |
| RENAISSANCE TECHNOLOGIES LLC | US$154.2萬 | 0.00% |
| Kalehua Capital Management LLC | US$123.8萬 | 0.88% |
| MILLENNIUM MANAGEMENT LLC | US$72.0萬 | 0.00% |
| F/m Investments LLC | US$71.2萬 | 0.05% |
| EMERALD MUTUAL FUND ADVISERS TRUST | US$71.2萬 | 0.03% |
| JPMORGAN CHASE & CO | US$70.4萬 | 0.00% |
| XTX Topco Ltd | US$68.5萬 | 0.01% |
| NORTHERN TRUST CORP | US$65.3萬 | 0.00% |
| Trexquant Investment LP | US$63.6萬 | 0.00% |
| GOLDMAN SACHS GROUP INC | US$57.2萬 | 0.00% |
| RAYMOND JAMES FINANCIAL INC | US$48.5萬 | 0.00% |
| BOOTHBAY FUND MANAGEMENT, LLC | US$47.5萬 | 0.01% |
| ACADIAN ASSET MANAGEMENT LLC | US$47.1萬 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$47.0萬 | 0.00% |
| MORGAN STANLEY | US$46.6萬 | 0.00% |
| FMR LLC | US$44.0萬 | 0.00% |
| Quantinno Capital Management LP | US$40.7萬 | 0.00% |
| MARSHALL WACE, LLP | US$38.9萬 | 0.00% |
| AIHC Capital Management Ltd | US$34.3萬 | 0.29% |
| Mariner, LLC | US$29.2萬 | 0.00% |
| Engineers Gate Manager LP | US$26.8萬 | 0.00% |
| Bank of New York Mellon Corp | US$24.6萬 | 0.00% |
| UBS Group AG | US$24.5萬 | 0.00% |
| Quadrature Capital Ltd | US$23.0萬 | 0.00% |
| ALGERT GLOBAL LLC | US$21.7萬 | 0.00% |
| Susquehanna Portfolio Strategies, LLC | US$21.6萬 | 0.00% |
| GUGGENHEIM CAPITAL LLC | US$16.0萬 | 0.00% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | US$15.2萬 | 0.00% |
| IEQ CAPITAL, LLC | US$14.5萬 | 0.00% |
| HRT FINANCIAL LP | US$12.2萬 | 0.00% |
| DEUTSCHE BANK AG\ | US$11.9萬 | 0.00% |
| RHUMBLINE ADVISERS | US$11.1萬 | 0.00% |
| CWM, LLC | US$11.1萬 | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | US$3.6萬 | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | US$3.4萬 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$2.9萬 | 0.00% |
| Russell Investments Group, Ltd. | US$2.4萬 | 0.00% |
| Vanguard Global Advisers, LLC | US$2.2萬 | 0.00% |
| North Star Investment Management Corp. | US$2.0萬 | 0.00% |
| Tower Research Capital LLC (TRC) | US$1.9萬 | 0.00% |
| Police & Firemen's Retirement System of New Jersey | US$1.6萬 | 0.00% |
| Essential Partners LLC | US$1.5萬 | 0.01% |
| TD Waterhouse Canada Inc. | US$1.0萬 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | US$9396.0 | 0.00% |
| GAMMA Investing LLC | US$8343.0 | 0.00% |
| Versant Capital Management, Inc | US$7822.0 | 0.00% |
| MAI Capital Management | US$6860.0 | 0.00% |
| Ameritas Investment Partners, Inc. | US$6769.0 | 0.00% |
| Legal & General Group Plc | US$5954.0 | 0.00% |
| DUNCKER STREETT & CO INC | US$4947.0 | 0.00% |
| EverSource Wealth Advisors, LLC | US$4291.0 | 0.00% |
| CITIGROUP INC | US$3487.0 | 0.00% |
| Allworth Financial LP | US$3295.0 | 0.00% |
| Advisory Services Network, LLC | US$2773.0 | 0.00% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | US$2547.0 | 0.00% |
| Sterling Capital Management LLC | US$2490.0 | 0.00% |
| OSAIC HOLDINGS, INC. | US$1528.0 | 0.00% |
| True Wealth Design, LLC | US$1121.0 | 0.00% |
| ROYAL BANK OF CANADA | US$1000.0 | 0.00% |
| Arax Advisory Partners | US$974.0 | 0.00% |
| ROTHSCHILD INVESTMENT LLC | US$815.0 | 0.00% |
| Keating Financial Advisory Services, Inc. | US$713.0 | 0.00% |
| Root Financial Partners, LLC | US$713.0 | 0.00% |
| Farther Finance Advisors, LLC | US$683.0 | 0.00% |
| Optiver Holding B.V. | US$679.0 | 0.00% |
| IFP Advisors, Inc | US$509.0 | 0.00% |
| Wealth Preservation Advisors, LLC | US$498.0 | 0.00% |
| Bare Financial Services, Inc | US$498.0 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | US$453.0 | 0.00% |
| Fortitude Family Office, LLC | US$441.0 | 0.00% |
| Basecamp Wealth Advisors LLC | US$283.0 | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | US$266.5 | 0.00% |
| SJS Investment Consulting Inc. | US$250.0 | 0.00% |
| Sunbelt Securities, Inc. | US$192.0 | 0.00% |
| FIFTH THIRD BANCORP | US$125.0 | 0.00% |
| JPL Wealth Management, LLC | US$23.0 | 0.00% |
| SBI Securities Co., Ltd. | US$11.0 | 0.00% |