| JANUS HENDERSON GROUP PLC | US$9351.8萬 | 0.04% |
| Cormorant Asset Management, LP | US$7729.9萬 | 3.88% |
| BlackRock, Inc. | US$4538.2萬 | 0.00% |
| Vivo Capital, LLC | US$4065.7萬 | 3.38% |
| BRAIDWELL LP | US$3938.2萬 | 1.31% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | US$3617.4萬 | 0.06% |
| Vestal Point Capital, LP | US$3592.5萬 | 1.00% |
| Driehaus Capital Management LLC | US$3156.1萬 | 0.23% |
| PERCEPTIVE ADVISORS LLC | US$2754.9萬 | 0.54% |
| Balyasny Asset Management L.P. | US$2168.4萬 | 0.03% |
| DEERFIELD MANAGEMENT COMPANY, L.P. | US$2065.1萬 | 0.24% |
| RA CAPITAL MANAGEMENT, L.P. | US$1933.7萬 | 0.20% |
| GREAT POINT PARTNERS LLC | US$1605.3萬 | 3.69% |
| MPM BIOIMPACT LLC | US$1548.2萬 | 1.20% |
| Ikarian Capital, LLC | US$1216.0萬 | 0.99% |
| WELLINGTON MANAGEMENT GROUP LLP | US$997.3萬 | 0.00% |
| MORGAN STANLEY | US$968.8萬 | 0.00% |
| EVENTIDE ASSET MANAGEMENT, LLC | US$948.7萬 | 0.16% |
| SEVEN GRAND MANAGERS, LLC | US$875.6萬 | 0.59% |
| ACUTA CAPITAL PARTNERS, LLC | US$817.2萬 | 5.81% |
| STATE STREET CORP | US$789.8萬 | 0.00% |
| GEODE CAPITAL MANAGEMENT, LLC | US$647.4萬 | 0.00% |
| Sio Capital Management, LLC | US$628.1萬 | 0.90% |
| GOLDMAN SACHS GROUP INC | US$542.7萬 | 0.00% |
| B Group, Inc. | US$492.5萬 | 3.65% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | US$441.3萬 | 0.00% |
| Walleye Capital LLC | US$391.9萬 | 0.02% |
| MILLENNIUM MANAGEMENT LLC | US$385.5萬 | 0.00% |
| BOOTHBAY FUND MANAGEMENT, LLC | US$374.3萬 | 0.05% |
| AMERIPRISE FINANCIAL INC | US$365.0萬 | 0.00% |
| Woodline Partners LP | US$333.2萬 | 0.01% |
| Parkman Healthcare Partners LLC | US$292.6萬 | 0.30% |
| ORBIMED ADVISORS LLC | US$291.9萬 | 0.06% |
| Artia Global Partners LP | US$280.3萬 | 0.56% |
| NORTHERN TRUST CORP | US$272.7萬 | 0.00% |
| ADAR1 Capital Management, LLC | US$247.4萬 | 0.15% |
| KVP Capital Advisors, LP | US$232.1萬 | 1.73% |
| BANK OF AMERICA CORP /DE/ | US$141.7萬 | 0.00% |
| PLATINUM INVESTMENT MANAGEMENT LTD | US$139.6萬 | 0.35% |
| D. E. Shaw & Co., Inc. | US$112.7萬 | 0.00% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | US$111.8萬 | 0.00% |
| SUPERSTRING CAPITAL MANAGEMENT LP | US$97.1萬 | 0.69% |
| UBS Group AG | US$96.9萬 | 0.00% |
| Bank of New York Mellon Corp | US$96.7萬 | 0.00% |
| Schonfeld Strategic Advisors LLC | US$96.6萬 | 0.01% |
| AdvisorShares Investments LLC | US$92.0萬 | 0.17% |
| SEI INVESTMENTS CO | US$81.6萬 | 0.00% |
| Ghisallo Capital Management LLC | US$80.3萬 | 0.02% |
| Informed Momentum Co LLC | US$67.1萬 | 0.08% |
| Nuveen, LLC | US$60.8萬 | 0.00% |
| RHUMBLINE ADVISERS | US$56.6萬 | 0.00% |
| Trexquant Investment LP | US$54.4萬 | 0.00% |
| Quadrature Capital Ltd | US$47.4萬 | 0.01% |
| LPL Financial LLC | US$47.4萬 | 0.00% |
| JANE STREET GROUP, LLC | US$46.7萬 | 0.00% |
| Seven Fleet Capital Management LP | US$46.7萬 | 0.15% |
| Invesco Ltd. | US$45.9萬 | 0.00% |
| DEUTSCHE BANK AG\ | US$45.7萬 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | US$44.2萬 | 0.00% |
| PRICE T ROWE ASSOCIATES INC /MD/ | US$36.1萬 | 0.00% |
| DNB Asset Management AS | US$32.4萬 | 0.00% |
| MetLife Investment Management, LLC | US$28.5萬 | 0.00% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | US$27.6萬 | 0.00% |
| JPMORGAN CHASE & CO | US$26.5萬 | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | US$23.8萬 | 0.00% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | US$22.9萬 | 0.00% |
| Virtu Financial LLC | US$22.8萬 | 0.01% |
| BARCLAYS PLC | US$22.5萬 | 0.00% |
| Vanguard Global Advisers, LLC | US$22.3萬 | 0.00% |
| STRS OHIO | US$19.7萬 | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | US$19.0萬 | 0.00% |
| WELLS FARGO & COMPANY/MN | US$18.5萬 | 0.00% |
| Persistent Asset Partners Ltd | US$16.9萬 | 0.06% |
| Aquatic Capital Management LLC | US$14.9萬 | 0.00% |
| Police & Firemen's Retirement System of New Jersey | US$14.9萬 | 0.00% |
| Russell Investments Group, Ltd. | US$6.4萬 | 0.00% |
| FMR LLC | US$6.0萬 | 0.00% |
| Legal & General Group Plc | US$4.5萬 | 0.00% |
| Tower Research Capital LLC (TRC) | US$4.4萬 | 0.00% |
| China Universal Asset Management Co., Ltd. | US$3.6萬 | 0.00% |
| Ameritas Investment Partners, Inc. | US$3.4萬 | 0.00% |
| ROYAL BANK OF CANADA | US$3.0萬 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | US$2.8萬 | 0.00% |
| CITIGROUP INC | US$2.2萬 | 0.00% |
| Sterling Capital Management LLC | US$3284.0 | 0.00% |
| GAMMA Investing LLC | US$2408.0 | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | US$1146.4 | 0.00% |
| CWM, LLC | US$803.0 | 0.00% |
| Bell Investment Advisors, Inc | US$438.0 | 0.00% |
| SBI Securities Co., Ltd. | US$365.0 | 0.00% |
| Allworth Financial LP | US$219.0 | 0.00% |
| MAI Capital Management | US$73.0 | 0.00% |
| TWIN PEAKS WEALTH ADVISORS, LLC | US$73.0 | 0.00% |