BI
Bvf Inc/il 13F Holdings & Position Changes (Q2 2026)
Bvf Inc/ilCIK: 0001056807
Sector-focusedMomentum followerDiversified strategy
Total reported value
$3.9B
Reporting period: 2026-06-30 · Number of holdings: 44
BVF INC/IL disclosed 44 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $3.9B and a quarterly turnover rate of 33.7%.
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Personality snowflake
- Concentration
- 24.93
- Portfolio Stability
- 33.72
- Momentum
- 100
- Sector conviction
- 100
- Diversification
- 88
- Sizing Uniformity
- 86.65
Bvf Inc/il's disclosed holdings carry a Herfindahl concentration index of 0.062 — mathematically equivalent to about 16 equally-sized positions, well below its 44 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 1.34), with a handful of outsized bets alongside many smaller positions.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 2.2 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 17% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govAdd XOMA
+193.1% $241.5M
Add RVMD
+3.8% $277.5M
Trim KYMR
-29.6% -$14.3M
Add GHRS
0.0% $110.9M
Trim NKTR
-6.6% -$17.2M
Trim MLTX
0.0% $13.3M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 14.20% | +5.35% | +3.79% | |
| 2 | KYMR | Kymera Therapeutics Inc | Stock-Other | 11.35% | -3.25% | -29.63% | |
| 3 | XOMA | Xoma Royalty Corporation | Stock-Other | 8.25% | +5.66% | +193.14% | |
| 4 | MLTX | Moonlake Immunotherapeutics | Stock-Other | 7.97% | -1.53% | — | |
| 5 | GHRS | GH Research PLC | Stock-Other | 5.95% | +2.08% | — | |
| 6 | GPCR | Structure Therapeutics Inc | Stock-Other | 4.62% | -0.69% | -2.67% | |
| 7 | NKTR | Nektar Therapeutics | Stock-Other | 4.27% | -1.60% | -6.58% | |
| 8 | MIRM | Mirum Pharmaceuticals Inc | Stock-Other | 3.16% | -1.50% | -33.36% | |
| 9 | XNCR | Xencor Inc | Stock-Other | 2.94% | +0.20% | — | |
| 10 | ALKS | Alkermes plc | Stock-Healthcare | 2.89% | +0.64% | +7.74% | |
| 11 | GLUE | Monte Rosa Therapeutics Inc | Stock-Other | 2.76% | +0.42% | — | |
| 12 | CGEM | Cullinan Therapeutics Inc | Stock-Other | 2.68% | +0.08% | — | |
| 13 | PVLA | Palvella Therapeutics Inc | Stock-Other | 2.63% | -1.19% | -29.99% | |
| 14 | ZYME | Zymeworks Inc | Stock-Other | 2.44% | -0.54% | -2.28% | |
| 15 | KURA | Kura Oncology Inc | Stock-Other | 2.37% | +0.18% | — | |
| 16 | IRON | Disc Medicine Inc | Stock-Other | 2.16% | -0.43% | -9.33% | |
| 17 | STOK | Stoke Therapeutics Inc | Stock-Other | 2.13% | -0.51% | — | |
| 18 | OLMA | Olema Pharmaceuticals Inc | Stock-Other | 1.69% | -0.83% | — | |
| 19 | ANNX | Annexon Inc | Stock-Other | 1.27% | -0.27% | — | |
| 20 | ✓ | Crescent Biopharma Inc. | Stock-Other | 1.27% | -0.34% | — | |
| 21 | ACIU | AC Immune SA | Stock-Other | 1.21% | -0.53% | — | |
| 22 | TYRA | Tyra Biosciences Inc | Stock-Other | 1.21% | -1.20% | -25.30% | |
| 23 | STRO | Sutro Biopharma Inc | Stock-Other | 1.06% | +0.07% | — | |
| 24 | IMCR | Immunocore Holdings Plc-adr | Stock-Other | 1.05% | -0.19% | — | |
| 25 | AVTX | Avalo Therapeutics Inc | Stock-Other | 0.98% | +0.20% | +27.11% | |
| 26 | FDMT | 4d Molecular Therapeutics In | Stock-Other | 0.98% | +0.13% | — | |
| 27 | QTTB | Q32 Bio Inc | Stock-Other | 0.77% | +0.77% | NEW | |
| 28 | AVR | Anteris Technologies Global | Stock-Other | 0.76% | +0.23% | — | |
| 29 | FHTX | Foghorn Therapeutics Inc | Stock-Other | 0.73% | -0.16% | — | |
| 30 | ABSI | Absci CORP | Stock-Other | 0.70% | +0.70% | NEW | |
| 31 | ELDN | Eledon Pharmaceuticals Inc | Stock-Other | 0.63% | +0.01% | — | |
| 32 | IVVD | Invivyd Inc | Stock-Other | 0.63% | -0.18% | +44.25% | |
| 33 | SGMT | Sagimet Biosciences Inc-a | Stock-Other | 0.49% | +0.49% | NEW | |
| 34 | OKUR | Onkure Therapeutics Inc-a | Stock-Other | 0.38% | +0.12% | +63.51% | |
| 35 | IMUX | Immunic Inc | Stock-Other | 0.30% | +0.30% | NEW | |
| 36 | XFOR | X4 Pharmaceuticals Inc | Stock-Other | 0.27% | -0.02% | — | |
| 37 | IMA | Imagenebio Inc | Stock-Other | 0.17% | -0.01% | — | |
| 38 | TCRX | Tscan Therapeutics Inc | Stock-Other | 0.14% | -0.04% | — | |
| 39 | ✓ | Stock-Other | 0.14% | +0.14% | NEW | ||
| 40 | MOLN | Molecular Partners AG -adr | Stock-Other | 0.13% | -0.04% | — | |
| 41 | TENX | Tenax Therapeutics Inc | Stock-Other | 0.13% | -0.04% | — | |
| 42 | ✓ | Entera Bio LTD | Stock-Other | 0.11% | +0.11% | NEW | |
| 43 | IVA | Inventiva SA - Adr | Stock-Other | 0.07% | -0.05% | — | |
| 44 | ✓ | Stock-Other | 0.01% | +0.01% | NEW |
Portfolio Performance
Performance for Q3 2026
+16%
Performance Last 4 Quarters
+59.9%
- Stdev
- +32.2%
- Beta
- +0.76
- Alpha
- +10.8%
- Max Drawdown
- -28.3%
- Annualized Perf
- +23.1%
- Batting Avg vs S&P
- +38.9%
- Sortino
- +1.48
- Stutzer
- +0.24
- Treynor
- +0.34
- Sterling
- +0.94
- Calmar
- +0.82
- Information Ratio
- +0.19
- Tracking Error
- +30.8%
- Stdev Down
- +17.5%
- Winning Months %
- +58.3%
- Losing Months %
- +41.7%
- Best 12 Months
- +92.2%
- Worst 12 Months
- -24.4%
- Efficiency Ratio
- +0.32
- Sharpe
- +0.81
- Stdev Sectors
- 0%
- Skewness
- +0.23
- Kurtosis
- -0.04
- Upside Potential
- +3.29
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 44 | $3.9B | 34 | ||
| 2026 Q1 | 41 | $3.1B | 29 | ||
| 2025 Q4 | 41 | $3.0B | 55 | ||
| 2025 Q3 | 46 | $2.5B | 78 | ||
| 2025 Q2 | 44 | $2.8B | 0 | ||
| 2025 Q1 | 51 | $2.5B | 100 | ||
| 2024 Q4 | 53 | $3.0B | 0 | ||
| 2024 Q3 | 55 | $3.4B | 0 | ||
| 2024 Q2 | 60 | $3.6B | 0 | ||
| 2024 Q1 | 62 | $3.6B | 0 | ||
| 2023 Q4 | 70 | $4.0B | 0 | ||
| 2023 Q3 | 69 | $3.7B | 0 | ||
| 2023 Q2 | 67 | $3.6B | 0 | ||
| 2023 Q1 | 72 | $2.7B | 0 | ||
| 2022 Q4 | 78 | $2.4B | 0 | ||
| 2022 Q3 | 80 | $2.4B | 0 | ||
| 2022 Q2 | 79 | $2.1B | 0 | ||
| 2022 Q1 | 81 | $2.5B | 0 | ||
| 2021 Q4 | 83 | $2.8B | 0 | ||
| 2021 Q3 | 75 | $2.6B | 0 | ||
| 2021 Q2 | 70 | $2.7B | 54 | ||
| 2021 Q1 | 67 | $2.7B | 55 | ||
| 2020 Q4 | 68 | $2.5B | 69 | ||
| 2020 Q3 | 62 | $1.8B | 54 | ||
| 2020 Q2 | 57 | $1.6B | 62 | ||
| 2020 Q1 | 57 | $1.1B | 49 | ||
| 2019 Q4 | 57 | $1.3B | 71 | ||
| 2019 Q3 | 59 | $951.8M | 55 | ||
| 2019 Q2 | 56 | $915.6M | 39 | ||
| 2019 Q1 | 53 | $893.1M | 41 | ||
| 2018 Q4 | 55 | $765.2M | 46 | ||
| 2018 Q3 | 57 | $1.1B | 31 | ||
| 2018 Q2 | 51 | $1.0B | 48 | ||
| 2018 Q1 | 43 | $986.5M | 58 | ||
| 2017 Q4 | 43 | $829.5M | 55 | ||
| 2017 Q3 | 37 | $786.7M | 52 | ||
| 2017 Q2 | 34 | $644.0M | 42 | ||
| 2017 Q1 | 30 | $587.9M | 54 | ||
| 2016 Q4 | 29 | $497.7M | 39 | ||
| 2016 Q3 | 29 | $530.7M | 50 | ||
| 2016 Q2 | 34 | $469.4M | 59 | ||
| 2016 Q1 | 32 | $404.1M | 47 | ||
| 2015 Q4 | 30 | $586.8M | 39 | ||
| 2015 Q3 | 27 | $495.0M | 40 | ||
| 2015 Q2 | 30 | $566.6M | 43 | ||
| 2015 Q1 | 30 | $478.2M | 37 | ||
| 2014 Q4 | 31 | $514.1M | 52 | ||
| 2014 Q3 | 32 | $481.6M | 60 | ||
| 2014 Q2 | 29 | $632.3M | 34 | ||
| 2014 Q1 | 28 | $645.1M | 31 | ||
| 2013 Q4 | 26 | $571.6M | 32 | ||
| 2013 Q3 | 26 | $581.2M | 39 | ||
| 2013 Q2 | 24 | $515.3M | 0 |
Holding changes this quarter
Bvf Inc/il's most significant position changes for 2026-06-30: Sold out: Compass Therapeutics Inc (CMPX); Sold out: Septerna Inc (SEPN); New buy: Q32 Bio Inc (QTTB); New buy: Absci CORP (ABSI); New buy: Sagimet Biosciences Inc-a (SGMT).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | XOMA | Xoma Royalty Corporation | +5.7% | +193.14% | Add |
| 2 | RVMD | Revolution Medicines Inc | +5.4% | +3.79% | Add |
| 3 | GHRS | GH Research PLC | +2.1% | — | Unchanged |
| 4 | QTTB | Q32 Bio Inc | +0.8% | NEW | New buy |
| 5 | ABSI | Absci CORP | +0.7% | NEW | New buy |
| 6 | ALKS | Alkermes plc | +0.6% | +7.74% | Add |
| 7 | SGMT | Sagimet Biosciences Inc-a | +0.5% | NEW | New buy |
| 8 | GLUE | Monte Rosa Therapeutics Inc | +0.4% | — | Unchanged |
| 9 | IMUX | Immunic Inc | +0.3% | NEW | New buy |
| 10 | AVR | Anteris Technologies Global | +0.2% | — | Unchanged |
| 11 | XNCR | Xencor Inc | +0.2% | — | Unchanged |
| 12 | AVTX | Avalo Therapeutics Inc | +0.2% | +27.11% | Add |
| 13 | KURA | Kura Oncology Inc | +0.2% | — | Unchanged |
| 14 | ✓ | +0.1% | NEW | New buy | |
| 15 | FDMT | 4d Molecular Therapeutics In | +0.1% | — | Unchanged |
| 16 | OKUR | Onkure Therapeutics Inc-a | +0.1% | +63.51% | Add |
| 17 | ✓ | Entera Bio LTD | +0.1% | NEW | New buy |
| 18 | CGEM | Cullinan Therapeutics Inc | +0.1% | — | Unchanged |
| 19 | STRO | Sutro Biopharma Inc | +0.1% | — | Unchanged |
| 20 | ELDN | Eledon Pharmaceuticals Inc | 0% | — | Unchanged |
| 21 | ✓ | 0% | NEW | New buy | |
| 22 | IMA | Imagenebio Inc | 0% | — | Unchanged |
| 23 | XFOR | X4 Pharmaceuticals Inc | 0% | — | Unchanged |
| 24 | TENX | Tenax Therapeutics Inc | 0% | — | Unchanged |
| 25 | MOLN | Molecular Partners AG -adr | 0% | — | Unchanged |
| 26 | TCRX | Tscan Therapeutics Inc | 0% | — | Unchanged |
| 27 | IVA | Inventiva SA - Adr | -0.1% | — | Unchanged |
| 28 | ✓ | Engene Holdings Inc | -0.1% | EXIT | Sold out |
| 29 | FHTX | Foghorn Therapeutics Inc | -0.2% | — | Unchanged |
| 30 | IVVD | Invivyd Inc | -0.2% | +44.25% | Add |
| 31 | IMCR | Immunocore Holdings Plc-adr | -0.2% | — | Unchanged |
| 32 | VTLUSD | Immunic Inc | -0.3% | EXIT | Sold out |
| 33 | ANNX | Annexon Inc | -0.3% | — | Unchanged |
| 34 | ✓ | Crescent Biopharma Inc. | -0.3% | — | Unchanged |
| 35 | IRON | Disc Medicine Inc | -0.4% | -9.33% | Trim |
| 36 | STOK | Stoke Therapeutics Inc | -0.5% | — | Unchanged |
| 37 | ACIU | AC Immune SA | -0.5% | — | Unchanged |
| 38 | ZYME | Zymeworks Inc | -0.5% | -2.28% | Trim |
| 39 | GPCR | Structure Therapeutics Inc | -0.7% | -2.67% | Trim |
| 40 | OLMA | Olema Pharmaceuticals Inc | -0.8% | — | Unchanged |
| 41 | SEPN | Septerna Inc | -1% | EXIT | Sold out |
| 42 | PVLA | Palvella Therapeutics Inc | -1.2% | -29.99% | Trim |
| 43 | TYRA | Tyra Biosciences Inc | -1.2% | -25.30% | Trim |
| 44 | CMPX | Compass Therapeutics Inc | -1.3% | EXIT | Sold out |
| 45 | MIRM | Mirum Pharmaceuticals Inc | -1.5% | -33.36% | Trim |
| 46 | MLTX | Moonlake Immunotherapeutics | -1.5% | — | Unchanged |
| 47 | NKTR | Nektar Therapeutics | -1.6% | -6.58% | Trim |
| 48 | KYMR | Kymera Therapeutics Inc | -3.3% | -29.63% | Trim |
Filing History
FAQ
What is Bvf Inc/il and what type of investor is it?
Bvf Inc/il is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $3.9B, spread across 44 disclosed positions.
What are Bvf Inc/il's largest equity positions?
Based on the latest 13F filing, Bvf Inc/il's top holdings by market value are:
1. Revolution Medicines Inc (RVMD) — $555.3M (14.2%)
2. Kymera Therapeutics Inc (KYMR) — $444.0M (11.3%)
3. Xoma Royalty Corporation (XOMA) — $322.7M (8.3%)
4. Moonlake Immunotherapeutics (MLTX) — $311.5M (8.0%)
5. GH Research PLC (GHRS) — $232.5M (6.0%)
What changes did Bvf Inc/il make in its most recent portfolio filing?
In the latest reported quarter, Bvf Inc/il made 25 notable position adjustments: 7 new positions were initiated, 6 existing holdings were added to, 8 positions were partially reduced, and 4 were completely exited. The largest of these moves: Sold out: Compass Therapeutics Inc (CMPX); Sold out: Septerna Inc (SEPN); New buy: Q32 Bio Inc (QTTB); New buy: Absci CORP (ABSI); New buy: Sagimet Biosciences Inc-a (SGMT)
What sectors does Bvf Inc/il focus on?
Bvf Inc/il is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
💡
Data Source Notice: AlphaSMO is the web's most authoritative 13F / Inside Trader database. Institutional holdings and insider trades presented here are precisely computed to deliver accurate portfolio reporting.
Investment Profile
Bvf Inc/il returned an annualized 23.1% over the trailing 36 months — outperforming the S&P 500 by 10.8 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.76 (less volatile than the market) and a 39% quarterly batting average against the index.
Its portfolio is broadly diversified and moderately active, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 34 over the past 4 quarters — a shift toward more active trading.
It has added to its RVMD position over the past two quarters (+$287.9M, now $555.3M), while trimming OLMA over the same stretch (-$66.1M, still holding $66.3M).
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