CIK: 0001056807
Total reported value
$3.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ARRYEUR | Array Biopharma INC | Stock-Other | 9.34% | — | -27.90% | |
| 2 | ✓ | Merus N V | Stock-Other | 7.51% | — | +0.55% | |
| 3 | 2655787D | Blueprint Medicines CORP | Stock-Other | 5.06% | — | -1.74% | |
| 4 | KURA | Kura Oncology INC | Stock-Other | 4.64% | -0.82% | -10.09% | |
| 5 | FPRX | Five Prime Therapeutics INC | Stock-Other | 4.60% | — | +10.17% | |
| 6 | ACIU | AC Immune SA | Stock-Other | 4.22% | -0.36% | +234.32% | |
| 7 | RCUS | Arcus Biosciences INC | Stock-Other | 3.93% | — | +16.53% | |
| 8 | INFIQ | Infinity Pharmaceuticals INC | Stock-Other | 3.67% | — | — | |
| 9 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 3.54% | — | -37.33% | |
| 10 | CYTK | Cytokinetics INC | Stock-Healthcare | 3.44% | — | -8.40% | |
| 11 | ARQLUSD | Arqule INC | Stock-Other | 3.38% | — | +1.26% | |
| 12 | REPL | Replimune Group INC | Stock-Other | 2.74% | — | +78.61% | |
| 13 | XOMA | Xoma Royalty Corporation | Stock-Other | 2.45% | +0.27% | — | |
| 14 | ✓ | Molecular Templates Inc | Stock-Other | 2.33% | — | +6.38% | |
| 15 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 2.30% | — | +15.24% | |
| 16 | CALAEUR | Calithera Biosciences INC | Stock-Other | 2.28% | — | -8.33% | |
| 17 | CCXIEUR | Chemocentryx INC | Stock-Other | 2.28% | — | -78.10% | |
| 18 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 2.04% | — | — | |
| 19 | CNCEEUR | Concert Pharmaceuticals INC | Stock-Other | 1.87% | — | +20.43% | |
| 20 | ANAB | Anaptysbio INC | Stock-Other | 1.80% | — | — | |
| 21 | ✓ | Galmed Pharmaceuticals LTD | Stock-Other | 1.72% | — | — | |
| 22 | PTGX | Protagonist Therapeutics INC | Stock-Other | 1.58% | — | -31.49% | |
| 23 | PIRSEUR | Pieris Pharmaceuticals INC | Stock-Other | 1.52% | — | -45.58% | |
| 24 | ✓ | Mersana Therapeutics INC | Stock-Other | 1.47% | — | — | |
| 25 | CTMX | Cytomx Therapeutics INC | Stock-Other | 1.44% | — | — | |
| 26 | ✓ | Biolinerx Ltd-spons Adr | Stock-Other | 1.25% | — | — | |
| 27 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 1.17% | — | — | |
| 28 | ✓ | Veralto CORP | Stock-Other | 1.16% | — | — | |
| 29 | ARGX | Argenx Se - Adr | Stock-Healthcare | 1.13% | — | — | |
| 30 | FWRD | Forward Air Corporation | Stock-Other | 1.12% | — | — | |
| 31 | SBPHUSD | Spring Bank Pharmaceuticals | Stock-Other | 1.12% | — | — | |
| 32 | CLDNEUR | Eiger Biopharmaceuticals INC | Stock-Other | 1.06% | — | — | |
| 33 | VAC2USD | Vbi Vaccines INC | Stock-Other | 0.99% | — | -9.47% | |
| 34 | CRVS | Corvus Pharmaceuticals INC | Stock-Other | 0.95% | — | +11.58% | |
| 35 | MEIPUSD | Lite Strategy INC | Stock-Other | 0.93% | — | -9.40% | |
| 36 | NVLSEUR | Alpine Immune Sciences INC | Stock-Other | 0.92% | — | +86.88% | |
| 37 | CTIC1USD | Cti Biopharma CORP | Stock-Other | 0.75% | — | — | |
| 38 | BDQM | Albireo Pharma INC | Stock-Other | 0.72% | — | — | |
| 39 | VYGR | Voyager Therapeutics INC | Stock-Other | 0.67% | — | — | |
| 40 | SPRO | Spero Therapeutics INC | Stock-Other | 0.66% | — | -45.36% | |
| 41 | OVID | Ovid Therapeutics INC | Stock-Other | 0.65% | — | — | |
| 42 | ERYP1EUR | Erytech Pharma - Spon Adr | Stock-Other | 0.53% | — | — | |
| 43 | ✓ | Genocea Biosciences INC | Stock-Other | 0.52% | — | +53.06% | |
| 44 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.51% | — | -41.11% | |
| 45 | ✓ | Oncomed Pharmaceuticals INC | Stock-Other | 0.48% | — | +1.63% | |
| 46 | SNSSEUR | Viracta Therapeutics INC | Stock-Other | 0.31% | — | — | |
| 47 | ✓ | Vical INC Com New | Stock-Other | 0.31% | — | +77.24% | |
| 48 | RLM | Realm Therapeutics PLC -adr | Stock-Other | 0.27% | — | +69.84% | |
| 49 | SURFUSD | Surface Oncology INC | Stock-Other | 0.24% | — | — | |
| 50 | EPIEUR | Essa Pharma INC | Stock-Other | 0.22% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | REPL | Replimune Group INC | +1.6% | +78.61% | Add |
| 2 | ACIU | AC Immune SA | +1.5% | +234.32% | Add |
| 3 | FPRX | Five Prime Therapeutics INC | +1.2% | +10.17% | Add |
| 4 | ARQLUSD | Arqule INC | +1.1% | +1.26% | Add |
| 5 | 2655787D | Blueprint Medicines CORP | +1% | -1.74% | Trim |
| 6 | INFIQ | Infinity Pharmaceuticals INC | +1% | — | Unchanged |
| 7 | NVLSEUR | Alpine Immune Sciences INC | +0.6% | +86.88% | Add |
| 8 | DRNAUSD | Dicerna Pharmaceuticals INC | +0.6% | +15.24% | Add |
| 9 | XENE | Xenon Pharmaceuticals INC | +0.6% | — | Unchanged |
| 10 | ✓ | Molecular Templates Inc | +0.6% | +6.38% | Add |
| 11 | CALAEUR | Calithera Biosciences INC | +0.6% | -8.33% | Trim |
| 12 | RCUS | Arcus Biosciences INC | +0.5% | +16.53% | Add |
| 13 | ARRYEUR | Array Biopharma INC | +0.5% | -27.90% | Trim |
| 14 | ✓ | Genocea Biosciences INC | +0.3% | +53.06% | Add |
| 15 | FWRD | Forward Air Corporation | +0.3% | — | Unchanged |
| 16 | SNSSEUR | Viracta Therapeutics INC | +0.2% | — | Unchanged |
| 17 | RLM | Realm Therapeutics PLC -adr | +0.2% | +69.84% | Add |
| 18 | CLDNEUR | Eiger Biopharmaceuticals INC | +0.2% | — | Unchanged |
| 19 | PTGX | Protagonist Therapeutics INC | +0.1% | -31.49% | Trim |
| 20 | ARGX | Argenx Se - Adr | +0.1% | — | Unchanged |
| 21 | ✓ | Vical INC Com New | +0.1% | +77.24% | Add |
| 22 | CTIC1USD | Cti Biopharma CORP | +0.1% | — | Unchanged |
| 23 | ✓ | Oncomed Pharmaceuticals INC | +0.1% | +1.63% | Add |
| 24 | BDQM | Albireo Pharma INC | +0.1% | — | Unchanged |
| 25 | EPIEUR | Essa Pharma INC | +0.1% | — | Unchanged |
| 26 | ✓ | Galmed Pharmaceuticals LTD | 0% | — | Unchanged |
| 27 | CRVS | Corvus Pharmaceuticals INC | 0% | +11.58% | Add |
| 28 | CYTK | Cytokinetics INC | 0% | -8.40% | Trim |
| 29 | SNDX | Syndax Pharmaceuticals INC | 0% | — | Unchanged |
| 30 | CNCEEUR | Concert Pharmaceuticals INC | 0% | +20.43% | Add |
| 31 | SPRO | Spero Therapeutics INC | 0% | -45.36% | Trim |
| 32 | ANAB | Anaptysbio INC | 0% | — | Unchanged |
| 33 | MRTXEUR | Mirati Therapeutics INC | -0.3% | -37.33% | Trim |
| 34 | CFRXEUR | Contrafect CORP | -0.3% | — | Unchanged |
| 35 | ✓ | Cidara Therapeutics INC Com New | -0.4% | -41.11% | Trim |
| 36 | ✓ | Veralto CORP | -0.4% | — | Unchanged |
| 37 | KURA | Kura Oncology INC | -0.5% | -10.09% | Trim |
| 38 | ✓ | Merus N V | -0.8% | +0.55% | Add |
| 39 | PIRSEUR | Pieris Pharmaceuticals INC | -1.1% | -45.58% | Trim |
| 40 | XNCR | Xencor INC | -2.8% | -99.85% | Trim |
| 41 | CCXIEUR | Chemocentryx INC | -7.3% | -78.10% | Trim |
| 42 | ✓ | Mersana Therapeutics INC | — | NEW | New buy |
| 43 | CTMX | Cytomx Therapeutics INC | — | NEW | New buy |
| 44 | IMRX | Immuneering Corporation | — | EXIT | Sold out |
| 45 | VYGR | Voyager Therapeutics INC | — | NEW | New buy |
| 46 | OVID | Ovid Therapeutics INC | — | NEW | New buy |
| 47 | 4XC1 | Kalvista Pharmaceuticals INC | — | EXIT | Sold out |
| 48 | PRNB | Principia Biopharma INC | — | EXIT | Sold out |
| 49 | MACKEUR | Merrimack Pharmaceuticals In | — | EXIT | Sold out |
| 50 | ✓ | Loxo Oncology INC | — | EXIT | Sold out |