CIK: 0001056807
Total reported value
$3.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | KYMR | Kymera Therapeutics INC | Stock-Other | 12.63% | +0.19% | — | |
| 2 | RVMD | Revolution Medicines INC | Stock-Healthcare | 7.52% | -0.15% | -20.22% | |
| 3 | PTGX | Protagonist Therapeutics INC | Stock-Other | 6.90% | — | -20.25% | |
| 4 | MLTX | Moonlake Immunotherapeutics | Stock-Other | 5.74% | +0.74% | — | |
| 5 | CDTX | Cidara Therapeutics INC | Stock-Other | 5.49% | — | +79.83% | |
| 6 | GHRS | GH Research PLC | Stock-Other | 5.12% | +0.10% | — | |
| 7 | MIRM | Mirum Pharmaceuticals INC | Stock-Other | 4.44% | +0.68% | -45.85% | |
| 8 | XOMA | Xoma Royalty Corporation | Stock-Other | 4.05% | +0.27% | — | |
| 9 | GPCR | Structure Therapeutics INC | Stock-Other | 3.64% | -2.84% | +80.87% | |
| 10 | KURA | Kura Oncology INC | Stock-Other | 3.09% | -0.82% | +11.13% | |
| 11 | SEPN | Septerna INC | Stock-Other | 3.06% | -0.57% | -8.65% | |
| 12 | PVLA | Palvella Therapeutics INC | Stock-Other | 2.95% | +0.72% | +66.71% | |
| 13 | NKTR | Nektar Therapeutics | Stock-Other | 2.94% | +3.65% | — | |
| 14 | ZYME | Zymeworks INC | Stock-Other | 2.73% | -0.51% | -8.59% | |
| 15 | AXSM | Axsome Therapeutics INC | Stock-Healthcare | 2.40% | -0.28% | EXIT | |
| 16 | ACIU | AC Immune SA | Stock-Other | 2.32% | -0.36% | — | |
| 17 | IMCR | Immunocore Holdings Plc-adr | Stock-Other | 2.32% | -0.45% | +53.70% | |
| 18 | OLMA | Olema Pharmaceuticals INC | Stock-Other | 2.10% | -1.94% | — | |
| 19 | TYRA | Tyra Biosciences INC | Stock-Other | 2.07% | +0.53% | -7.46% | |
| 20 | ABVX | Abivax Sa-adr | Stock-Other | 1.92% | -2.31% | EXIT | |
| 21 | GLUE | Monte Rosa Therapeutics INC | Stock-Other | 1.70% | +0.32% | — | |
| 22 | FDMT | 4d Molecular Therapeutics In | Stock-Other | 1.63% | -0.32% | — | |
| 23 | STOK | Stoke Therapeutics INC | Stock-Other | 1.58% | +0.22% | — | |
| 24 | CGEM | Cullinan Therapeutics INC | Stock-Other | 1.38% | +0.60% | — | |
| 25 | CELC | Celcuity INC | Stock-Other | 1.32% | — | -81.00% | |
| 26 | XNCR | Xencor INC | Stock-Other | 1.30% | -0.94% | — | |
| 27 | FHTX | Foghorn Therapeutics INC | Stock-Other | 1.05% | -0.07% | — | |
| 28 | ANNX | Annexon INC | Stock-Other | 0.87% | — | — | |
| 29 | RPTX | Repare Therapeutics INC | Stock-Other | 0.74% | -0.90% | EXIT | |
| 30 | AVTX | Avalo Therapeutics INC | Stock-Other | 0.70% | -0.05% | +31.83% | |
| 31 | CMPX | Compass Therapeutics INC | Stock-Other | 0.67% | -0.09% | — | |
| 32 | ✓ | Crescent Biopharma INC. | Stock-Other | 0.67% | +0.51% | — | |
| 33 | ELDN | Eledon Pharmaceuticals INC | Stock-Other | 0.66% | +0.30% | — | |
| 34 | TCRX | Tscan Therapeutics INC | Stock-Other | 0.39% | — | — | |
| 35 | PEPG | Pepgen INC | Stock-Other | 0.36% | -0.42% | EXIT | |
| 36 | XFOR | X4 Pharmaceuticals INC | Stock-Other | 0.31% | -0.01% | — | |
| 37 | VTLUSD | Immunic INC | Stock-Other | 0.27% | +0.13% | — | |
| 38 | IMA | Imagenebio INC | Stock-Other | 0.26% | -0.01% | — | |
| 39 | MOLN | Molecular Partners AG -adr | Stock-Other | 0.20% | -0.03% | — | |
| 40 | IVA | Inventiva SA - Adr | Stock-Other | 0.16% | +0.01% | — | |
| 41 | TENX | Tenax Therapeutics INC | Stock-Other | 0.10% | +0.03% | — | |
| 42 | EPIEUR | Essa Pharma INC | Stock-Other | 0.09% | — | +33.37% | |
| 43 | SABS | Sab Biotherapeutics INC | Stock-Other | 0.08% | — | +1.62% | |
| 44 | FBRX | Forte Biosciences INC | Stock-Other | 0.04% | — | -88.89% | |
| 45 | ✓ | Engene Holdings INC | Stock-Other | 0.03% | — | — | |
| 46 | ✓ | Nls Pharmaceutics LTD | Stock-Other | 0.01% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | KYMR | Kymera Therapeutics INC | +6.9% | — | Add |
| 2 | CDTX | Cidara Therapeutics INC | +4.7% | +79.83% | Add |
| 3 | GPCR | Structure Therapeutics INC | +2.4% | +80.87% | Add |
| 4 | PVLA | Palvella Therapeutics INC | +2.2% | +66.71% | Add |
| 5 | SEPN | Septerna INC | +2% | -8.65% | Trim |
| 6 | PTGX | Protagonist Therapeutics INC | +1.8% | -20.25% | Trim |
| 7 | XOMA | Xoma Royalty Corporation | +1.6% | — | Trim |
| 8 | OLMA | Olema Pharmaceuticals INC | +1.3% | — | Unchanged |
| 9 | GHRS | GH Research PLC | +1.2% | — | Unchanged |
| 10 | FDMT | 4d Molecular Therapeutics In | +1% | — | Add |
| 11 | KURA | Kura Oncology INC | +1% | +11.13% | Add |
| 12 | ACIU | AC Immune SA | +0.8% | — | Unchanged |
| 13 | ZYME | Zymeworks INC | +0.6% | -8.59% | Trim |
| 14 | GLUE | Monte Rosa Therapeutics INC | +0.6% | — | Unchanged |
| 15 | TYRA | Tyra Biosciences INC | +0.6% | -7.46% | Trim |
| 16 | AVTX | Avalo Therapeutics INC | +0.4% | +31.83% | Add |
| 17 | RVMD | Revolution Medicines INC | +0.3% | -20.22% | Trim |
| 18 | RPTX | Repare Therapeutics INC | +0.3% | — | Unchanged |
| 19 | ANNX | Annexon INC | +0.3% | — | Unchanged |
| 20 | FHTX | Foghorn Therapeutics INC | +0.3% | — | Unchanged |
| 21 | XNCR | Xencor INC | +0.1% | — | Unchanged |
| 22 | TCRX | Tscan Therapeutics INC | +0.1% | — | Add |
| 23 | VTLUSD | Immunic INC | -0.1% | — | Trim |
| 24 | FBRX | Forte Biosciences INC | -0.2% | -88.89% | Trim |
| 25 | ELDN | Eledon Pharmaceuticals INC | -0.2% | — | Unchanged |
| 26 | CGEM | Cullinan Therapeutics INC | -0.4% | — | Unchanged |
| 27 | EPIEUR | Essa Pharma INC | -0.5% | +33.37% | Add |
| 28 | MIRM | Mirum Pharmaceuticals INC | -0.7% | -45.85% | Trim |
| 29 | AXSM | Axsome Therapeutics INC | -5.6% | -71.20% | Trim |
| 30 | MLTX | Moonlake Immunotherapeutics | -25.7% | — | Unchanged |
| 31 | NKTR | Nektar Therapeutics | — | NEW | New buy |
| 32 | IONS | Ionis Pharmaceuticals INC | — | EXIT | Sold out |
| 33 | IMCR | Immunocore Holdings Plc-adr | — | NEW | New buy |
| 34 | ABVX | Abivax Sa-adr | — | NEW | New buy |
| 35 | STOK | Stoke Therapeutics INC | — | NEW | New buy |
| 36 | LKFT | Lakefront Biotherapeutic-adr | — | EXIT | Sold out |
| 37 | ✓ | Verve Therapeutics INC | — | EXIT | Sold out |
| 38 | 2662247D | Iteos Therapeutics INC | — | EXIT | Sold out |
| 39 | CMPX | Compass Therapeutics INC | — | NEW | New buy |
| 40 | ✓ | Crescent Biopharma INC. | — | NEW | New buy |
| 41 | VSTM | Verastem INC | — | EXIT | Sold out |
| 42 | ✓ | Rapt Therapeutics INC | — | EXIT | Sold out |
| 43 | PEPG | Pepgen INC | — | NEW | New buy |
| 44 | ✓ | Third Harmonic Bio INC | — | EXIT | Sold out |
| 45 | XFOR | X4 Pharmaceuticals INC | — | NEW | New buy |
| 46 | VIGL | Vigil Neuroscience INC | — | EXIT | Sold out |
| 47 | IMA | Imagenebio INC | — | NEW | New buy |
| 48 | ✓ | Ikena Oncology INC | — | EXIT | Sold out |
| 49 | ALLKGUSD | Allakos INC | — | EXIT | Sold out |
| 50 | CTMX | Cytomx Therapeutics INC | — | EXIT | Sold out |