CIK: 0001056807
Total reported value
$3.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ✓ | Merus N V | Stock-Other | 8.69% | — | — | |
| 2 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 6.48% | — | — | |
| 3 | IONS | Ionis Pharmaceuticals INC | Stock-Healthcare | 5.89% | — | — | |
| 4 | ACIU | AC Immune SA | Stock-Other | 5.88% | -0.36% | +15.06% | |
| 5 | CYTK | Cytokinetics INC | Stock-Healthcare | 4.98% | — | -19.54% | |
| 6 | LKFT | Lakefront Biotherapeutic-adr | Stock-Other | 4.89% | — | — | |
| 7 | XOMA | Xoma Royalty Corporation | Stock-Other | 3.69% | +0.27% | — | |
| 8 | RCUS | Arcus Biosciences INC | Stock-Other | 3.42% | — | +1.24% | |
| 9 | 2655787D | Blueprint Medicines CORP | Stock-Other | 3.38% | — | — | |
| 10 | GLYCEUR | Glycomimetics INC | Stock-Other | 3.33% | — | — | |
| 11 | KURA | Kura Oncology INC | Stock-Other | 3.18% | -0.82% | -9.34% | |
| 12 | REPL | Replimune Group INC | Stock-Other | 2.56% | — | +1.46% | |
| 13 | DCPHEUR | Deciphera Pharmaceuticals In | Stock-Other | 2.53% | — | — | |
| 14 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 2.53% | — | -41.40% | |
| 15 | ✓ | Molecular Templates Inc | Stock-Other | 2.34% | — | +3.81% | |
| 16 | CALAEUR | Calithera Biosciences INC | Stock-Other | 2.19% | — | — | |
| 17 | PIRSEUR | Pieris Pharmaceuticals INC | Stock-Other | 1.92% | — | +35.29% | |
| 18 | INFIQ | Infinity Pharmaceuticals INC | Stock-Other | 1.89% | — | — | |
| 19 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 1.85% | — | — | |
| 20 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 1.65% | — | — | |
| 21 | ARQLUSD | Arqule INC | Stock-Other | 1.59% | — | +172.63% | |
| 22 | FPRX | Five Prime Therapeutics INC | Stock-Other | 1.53% | — | +25.37% | |
| 23 | CTMX | Cytomx Therapeutics INC | Stock-Other | 1.46% | — | +0.19% | |
| 24 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 1.39% | — | — | |
| 25 | IDYA | Ideaya Biosciences INC | Stock-Other | 1.36% | — | -4.25% | |
| 26 | ANAB | Anaptysbio INC | Stock-Other | 1.30% | — | +72.37% | |
| 27 | AKRO | Akero Therapeutics INC | Stock-Other | 1.13% | — | -27.24% | |
| 28 | SPRO | Spero Therapeutics INC | Stock-Other | 1.05% | — | — | |
| 29 | CCXIEUR | Chemocentryx INC | Stock-Other | 1.01% | — | — | |
| 30 | CRVS | Corvus Pharmaceuticals INC | Stock-Other | 0.96% | — | +9.82% | |
| 31 | EPIEUR | Essa Pharma INC | Stock-Other | 0.93% | — | +98.58% | |
| 32 | ✓ | Galmed Pharmaceuticals LTD | Stock-Other | 0.92% | — | — | |
| 33 | PTGX | Protagonist Therapeutics INC | Stock-Other | 0.86% | — | -35.83% | |
| 34 | ✓ | Prevail Therapeutics INC | Stock-Other | 0.85% | — | — | |
| 35 | ✓ | Veralto CORP | Stock-Other | 0.80% | — | — | |
| 36 | ASNSUSD | X4 Pharmaceuticals INC | Stock-Other | 0.79% | — | +2.23% | |
| 37 | OVID | Ovid Therapeutics INC | Stock-Other | 0.79% | — | -35.22% | |
| 38 | FWRD | Forward Air Corporation | Stock-Other | 0.69% | — | -23.58% | |
| 39 | ✓ | Mersana Therapeutics INC | Stock-Other | 0.67% | — | +61.81% | |
| 40 | GNCAQ | Genocea Biosciences INC | Stock-Other | 0.64% | — | — | |
| 41 | CTIC1USD | Cti Biopharma CORP | Stock-Other | 0.61% | — | — | |
| 42 | CLDNEUR | Eiger Biopharmaceuticals INC | Stock-Other | 0.58% | — | -20.07% | |
| 43 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.56% | — | +1.31% | |
| 44 | SBPHUSD | Spring Bank Pharmaceuticals | Stock-Other | 0.51% | — | +5.93% | |
| 45 | ✓ | Biolinerx LTD Adr | Stock-Other | 0.48% | — | — | |
| 46 | NVLSEUR | Alpine Immune Sciences INC | Stock-Other | 0.47% | — | -1.21% | |
| 47 | SNSSEUR | Viracta Therapeutics INC | Stock-Other | 0.47% | — | -8.50% | |
| 48 | ✓ | Gamida Cell LTD | Stock-Other | 0.45% | — | — | |
| 49 | MEIPUSD | Lite Strategy INC | Stock-Other | 0.39% | — | — | |
| 50 | STRO | Sutro Biopharma, Inc. | Stock-Other | 0.33% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ✓ | Merus N V | +1.3% | — | Unchanged |
| 2 | XOMA | Xoma Royalty Corporation | +0.8% | — | Unchanged |
| 3 | ARQLUSD | Arqule INC | +0.7% | +172.63% | Add |
| 4 | EPIEUR | Essa Pharma INC | +0.6% | +98.58% | Add |
| 5 | RCUS | Arcus Biosciences INC | +0.4% | +1.24% | Add |
| 6 | ACIU | AC Immune SA | -0.1% | +15.06% | Add |
| 7 | RGLSUSD | Regulus Therapeutics INC | -0.1% | — | Unchanged |
| 8 | SURFUSD | Surface Oncology INC | -0.2% | +6.37% | Add |
| 9 | ASNSUSD | X4 Pharmaceuticals INC | -0.2% | +2.23% | Add |
| 10 | BDQM | Albireo Pharma INC | -0.2% | -55.73% | Trim |
| 11 | CRVS | Corvus Pharmaceuticals INC | -0.2% | +9.82% | Add |
| 12 | ERYP1EUR | Erytech Pharma - Spon Adr | -0.2% | — | Unchanged |
| 13 | CLDNEUR | Eiger Biopharmaceuticals INC | -0.2% | -20.07% | Trim |
| 14 | REPL | Replimune Group INC | -0.2% | +1.46% | Add |
| 15 | MEIPUSD | Lite Strategy INC | -0.2% | — | Unchanged |
| 16 | AKRO | Akero Therapeutics INC | -0.2% | -27.24% | Trim |
| 17 | XENE | Xenon Pharmaceuticals INC | -0.2% | — | Unchanged |
| 18 | ✓ | Veralto CORP | -0.2% | — | Unchanged |
| 19 | GNCAQ | Genocea Biosciences INC | -0.3% | — | Unchanged |
| 20 | FWRD | Forward Air Corporation | -0.3% | -23.58% | Trim |
| 21 | DRNAUSD | Dicerna Pharmaceuticals INC | -0.3% | — | Unchanged |
| 22 | IDYA | Ideaya Biosciences INC | -0.3% | -4.25% | Trim |
| 23 | SNDX | Syndax Pharmaceuticals INC | -0.4% | — | Unchanged |
| 24 | ✓ | Mersana Therapeutics INC | -0.4% | +61.81% | Add |
| 25 | CCXIEUR | Chemocentryx INC | -0.4% | — | Unchanged |
| 26 | FPRX | Five Prime Therapeutics INC | -0.5% | +25.37% | Add |
| 27 | ✓ | Galmed Pharmaceuticals LTD | -0.6% | — | Unchanged |
| 28 | PTGX | Protagonist Therapeutics INC | -0.6% | -35.83% | Trim |
| 29 | ✓ | Molecular Templates Inc | -0.6% | +3.81% | Add |
| 30 | CALAEUR | Calithera Biosciences INC | -0.7% | — | Unchanged |
| 31 | CTMX | Cytomx Therapeutics INC | -0.8% | +0.19% | Add |
| 32 | 2655787D | Blueprint Medicines CORP | -1.1% | — | Unchanged |
| 33 | CYTK | Cytokinetics INC | -1.4% | -19.54% | Trim |
| 34 | INFIQ | Infinity Pharmaceuticals INC | -1.5% | — | Unchanged |
| 35 | KURA | Kura Oncology INC | -1.6% | -9.34% | Trim |
| 36 | MRTXEUR | Mirati Therapeutics INC | -3.4% | -41.40% | Trim |
| 37 | SWTXUSD | Springworks Therapeutics INC | — | NEW | New buy |
| 38 | IONS | Ionis Pharmaceuticals INC | — | NEW | New buy |
| 39 | ARRYEUR | Array Biopharma INC | — | EXIT | Sold out |
| 40 | LKFT | Lakefront Biotherapeutic-adr | — | NEW | New buy |
| 41 | GLYCEUR | Glycomimetics INC | — | NEW | New buy |
| 42 | DCPHEUR | Deciphera Pharmaceuticals In | — | NEW | New buy |
| 43 | CNCEEUR | Concert Pharmaceuticals INC | — | EXIT | Sold out |
| 44 | ✓ | Biolinerx Ltd-spons Adr | — | EXIT | Sold out |
| 45 | ✓ | Biolinerx LTD Adr | — | NEW | New buy |
| 46 | STRO | Sutro Biopharma, Inc. | — | NEW | New buy |
| 47 | RLM | Realm Therapeutics PLC -adr | — | EXIT | Sold out |
| 48 | KPTIEUR | Karyopharm Therapeutics INC | — | EXIT | Sold out |
| 49 | ✓ | Vical INC Com New | — | EXIT | Sold out |
| 50 | ADROEUR | Chinook Therapeutics INC | — | NEW | New buy |