Zymeworks Inc (ZYME) — Institutional Holders Breakdown (Q2 2026)

ZYME ranks #2958 out of 37501 tracked stocks by institutional interest — one of the most closely watched names in our coverage.

ZYME is a top-conviction position for EcoR1 Capital, LLC — at 29.2% of their entire disclosed 13F portfolio, it's one of their largest single bets, not just a passing allocation.

Rubric Capital Management LP has added to its ZYME position for two straight quarters, increasing it by $31.6M to reach $183.0M today.

Deutsche Bank Ag\ has trimmed its ZYME position for two straight quarters, cutting it by $31.6M while still holding $10.4M.

ZYME is up 0.9% today, and institutions have been net buyers of $15.4M this quarter — today's price move and the underlying institutional flow are pointing the same direction.

ZYME reported a net loss of $150.0M over the trailing twelve months.

• Not yet profitable — net loss of $150.0M over the trailing twelve months
• Revenue declined 69.8% year over year
• Net income declined year over year, from -$73.7M to -$150.0M
• Operating cash flow was negative, using $33.0M in cash
• Current ratio of 5.88x — enough short-term assets to cover short-term liabilities
• Liabilities run 0.29x equity — within a conventional range