CIK: 0001056807
Total reported value
$3.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | IONS | Ionis Pharmaceuticals INC | Stock-Healthcare | 9.98% | — | +132.99% | |
| 2 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 8.99% | — | +8.26% | |
| 3 | ACIU | AC Immune SA | Stock-Other | 7.33% | -0.36% | +0.39% | |
| 4 | PRNB | Principia Biopharma INC | Stock-Other | 7.13% | — | — | |
| 5 | CYTK | Cytokinetics INC | Stock-Healthcare | 5.80% | — | +73.00% | |
| 6 | XOMA | Xoma Royalty Corporation | Stock-Other | 5.47% | +0.27% | +47.05% | |
| 7 | ARQLUSD | Arqule INC | Stock-Other | 4.51% | — | +41.26% | |
| 8 | CALAEUR | Calithera Biosciences INC | Stock-Other | 4.14% | — | +41.61% | |
| 9 | ✓ | Molecular Templates Inc | Stock-Other | 3.56% | — | -0.66% | |
| 10 | ✓ | Merus N V | Stock-Other | 3.38% | — | -31.68% | |
| 11 | GLYCEUR | Glycomimetics INC | Stock-Other | 2.95% | — | — | |
| 12 | RCUS | Arcus Biosciences INC | Stock-Other | 2.74% | — | — | |
| 13 | FPRX | Five Prime Therapeutics INC | Stock-Other | 2.71% | — | +106.71% | |
| 14 | REPL | Replimune Group INC | Stock-Other | 2.51% | — | +31.97% | |
| 15 | KURA | Kura Oncology INC | Stock-Other | 2.08% | -0.82% | — | |
| 16 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 1.94% | — | +11.91% | |
| 17 | PHAT | Phathom Pharmaceuticals INC | Stock-Other | 1.86% | — | — | |
| 18 | PIRSEUR | Pieris Pharmaceuticals INC | Stock-Other | 1.47% | — | — | |
| 19 | INFIQ | Infinity Pharmaceuticals INC | Stock-Other | 1.27% | — | — | |
| 20 | IMVT | Immunovant INC | Stock-Other | 1.20% | — | — | |
| 21 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 1.17% | — | — | |
| 22 | ANAB | Anaptysbio INC | Stock-Other | 1.16% | — | +165.55% | |
| 23 | 2655787D | Blueprint Medicines CORP | Stock-Other | 1.12% | — | -57.99% | |
| 24 | EPIEUR | Essa Pharma INC | Stock-Other | 1.10% | — | — | |
| 25 | MEIPUSD | Lite Strategy INC | Stock-Other | 1.01% | — | +140.69% | |
| 26 | ASNSUSD | X4 Pharmaceuticals INC | Stock-Other | 0.93% | — | +92.42% | |
| 27 | CTIC1USD | Cti Biopharma CORP | Stock-Other | 0.83% | — | — | |
| 28 | IDYA | Ideaya Biosciences INC | Stock-Other | 0.82% | — | -0.35% | |
| 29 | ✓ | Galmed Pharmaceuticals LTD | Stock-Other | 0.80% | — | — | |
| 30 | ✓ | Prevail Therapeutics INC | Stock-Other | 0.79% | — | — | |
| 31 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.78% | — | — | |
| 32 | AKRO | Akero Therapeutics INC | Stock-Other | 0.76% | — | -4.40% | |
| 33 | CRVS | Corvus Pharmaceuticals INC | Stock-Other | 0.67% | — | -46.59% | |
| 34 | ✓ | Veralto CORP | Stock-Other | 0.64% | — | — | |
| 35 | SPRO | Spero Therapeutics INC | Stock-Other | 0.62% | — | -10.04% | |
| 36 | SELBUSD | Cartesian Therapeutics INC | Stock-Other | 0.59% | — | — | |
| 37 | ✓ | Mersana Therapeutics INC | Stock-Other | 0.51% | — | -70.79% | |
| 38 | CTMX | Cytomx Therapeutics INC | Stock-Other | 0.48% | — | -59.19% | |
| 39 | FWRD | Forward Air Corporation | Stock-Other | 0.46% | — | -85.71% | |
| 40 | PTGX | Protagonist Therapeutics INC | Stock-Other | 0.36% | — | — | |
| 41 | ERYP1EUR | Erytech Pharma - Spon Adr | Stock-Other | 0.34% | — | — | |
| 42 | NVLSEUR | Alpine Immune Sciences INC | Stock-Other | 0.33% | — | — | |
| 43 | GNCAQ | Genocea Biosciences INC | Stock-Other | 0.33% | — | — | |
| 44 | ✓ | Gamida Cell LTD | Stock-Other | 0.33% | — | — | |
| 45 | ARGX | Argenx Se - Adr | Stock-Healthcare | 0.30% | — | — | |
| 46 | ✓ | Biolinerx LTD Adr | Stock-Other | 0.30% | — | — | |
| 47 | STRO | Sutro Biopharma, Inc. | Stock-Other | 0.29% | — | +0.29% | |
| 48 | OVID | Ovid Therapeutics INC | Stock-Other | 0.23% | — | -68.37% | |
| 49 | CLDNEUR | Eiger Biopharmaceuticals INC | Stock-Other | 0.16% | — | -73.39% | |
| 50 | SNSSEUR | Viracta Therapeutics INC | Stock-Other | 0.16% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | IONS | Ionis Pharmaceuticals INC | +4.1% | +132.99% | Add |
| 2 | ARQLUSD | Arqule INC | +2.9% | +41.26% | Add |
| 3 | SWTXUSD | Springworks Therapeutics INC | +2.5% | +8.26% | Add |
| 4 | CALAEUR | Calithera Biosciences INC | +2% | +41.61% | Add |
| 5 | XOMA | Xoma Royalty Corporation | +1.8% | +47.05% | Add |
| 6 | ACIU | AC Immune SA | +1.5% | +0.39% | Add |
| 7 | ✓ | Molecular Templates Inc | +1.2% | -0.66% | Trim |
| 8 | FPRX | Five Prime Therapeutics INC | +1.2% | +106.71% | Add |
| 9 | CYTK | Cytokinetics INC | +0.8% | +73.00% | Add |
| 10 | MEIPUSD | Lite Strategy INC | +0.6% | +140.69% | Add |
| 11 | XENE | Xenon Pharmaceuticals INC | +0.3% | +11.91% | Add |
| 12 | CTIC1USD | Cti Biopharma CORP | +0.2% | — | Unchanged |
| 13 | ✓ | Cidara Therapeutics INC Com New | +0.2% | — | Unchanged |
| 14 | EPIEUR | Essa Pharma INC | +0.2% | — | Unchanged |
| 15 | ASNSUSD | X4 Pharmaceuticals INC | +0.1% | +92.42% | Add |
| 16 | ERYP1EUR | Erytech Pharma - Spon Adr | +0.1% | — | Unchanged |
| 17 | REPL | Replimune Group INC | -0.1% | +31.97% | Add |
| 18 | ✓ | Prevail Therapeutics INC | -0.1% | — | Unchanged |
| 19 | ✓ | Galmed Pharmaceuticals LTD | -0.1% | — | Unchanged |
| 20 | ANAB | Anaptysbio INC | -0.1% | +165.55% | Add |
| 21 | ✓ | Veralto CORP | -0.2% | — | Unchanged |
| 22 | SNDX | Syndax Pharmaceuticals INC | -0.2% | — | Unchanged |
| 23 | SNSSEUR | Viracta Therapeutics INC | -0.3% | — | Unchanged |
| 24 | GNCAQ | Genocea Biosciences INC | -0.3% | — | Unchanged |
| 25 | GLYCEUR | Glycomimetics INC | -0.4% | — | Unchanged |
| 26 | SBPHUSD | Spring Bank Pharmaceuticals | -0.4% | -30.98% | Trim |
| 27 | CLDNEUR | Eiger Biopharmaceuticals INC | -0.4% | -73.39% | Trim |
| 28 | SPRO | Spero Therapeutics INC | -0.4% | -10.04% | Trim |
| 29 | PIRSEUR | Pieris Pharmaceuticals INC | -0.5% | — | Unchanged |
| 30 | PTGX | Protagonist Therapeutics INC | -0.5% | — | Unchanged |
| 31 | IDYA | Ideaya Biosciences INC | -0.5% | -0.35% | Trim |
| 32 | OVID | Ovid Therapeutics INC | -0.6% | -68.37% | Trim |
| 33 | INFIQ | Infinity Pharmaceuticals INC | -0.6% | — | Unchanged |
| 34 | RCUS | Arcus Biosciences INC | -0.7% | — | Unchanged |
| 35 | CTMX | Cytomx Therapeutics INC | -1% | -59.19% | Trim |
| 36 | KURA | Kura Oncology INC | -1.1% | — | Unchanged |
| 37 | 2655787D | Blueprint Medicines CORP | -2.3% | -57.99% | Trim |
| 38 | ✓ | Merus N V | -5.3% | -31.68% | Trim |
| 39 | PRNB | Principia Biopharma INC | — | NEW | New buy |
| 40 | LKFT | Lakefront Biotherapeutic-adr | — | EXIT | Sold out |
| 41 | PHAT | Phathom Pharmaceuticals INC | — | NEW | New buy |
| 42 | DCPHEUR | Deciphera Pharmaceuticals In | — | EXIT | Sold out |
| 43 | MRTXEUR | Mirati Therapeutics INC | — | EXIT | Sold out |
| 44 | DRNAUSD | Dicerna Pharmaceuticals INC | — | EXIT | Sold out |
| 45 | IMVT | Immunovant INC | — | NEW | New buy |
| 46 | CCXIEUR | Chemocentryx INC | — | EXIT | Sold out |
| 47 | SELBUSD | Cartesian Therapeutics INC | — | NEW | New buy |
| 48 | ARGX | Argenx Se - Adr | — | NEW | New buy |
| 49 | MREO | Mereo Biopharma Group Pl-adr | — | EXIT | Sold out |
| 50 | ADROEUR | Chinook Therapeutics INC | — | EXIT | Sold out |