CIK: 0001056807
Total reported value
$3.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | FPRX | Five Prime Therapeutics INC | Stock-Other | 8.95% | — | +510.26% | |
| 2 | OLMA | Olema Pharmaceuticals INC | Stock-Other | 8.29% | -1.94% | — | |
| 3 | ✓ | Merus N V | Stock-Other | 5.71% | — | +25.48% | |
| 4 | XOMA | Xoma Royalty Corporation | Stock-Other | 5.40% | +0.27% | -15.58% | |
| 5 | RVMD | Revolution Medicines INC | Stock-Healthcare | 5.06% | -0.15% | +6.32% | |
| 6 | RPTX | Repare Therapeutics INC | Stock-Other | 4.28% | -0.90% | EXIT | |
| 7 | PTGX | Protagonist Therapeutics INC | Stock-Other | 3.84% | — | -7.35% | |
| 8 | KYMR | Kymera Therapeutics INC | Stock-Other | 3.83% | +0.19% | — | |
| 9 | RLAY | Relay Therapeutics INC | Stock-Other | 3.72% | — | -6.51% | |
| 10 | ARGX | Argenx Se - Adr | Stock-Healthcare | 3.20% | — | +395.43% | |
| 11 | EPIEUR | Essa Pharma INC | Stock-Other | 3.17% | — | -21.51% | |
| 12 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 2.34% | — | -0.50% | |
| 13 | IONS | Ionis Pharmaceuticals INC | Stock-Healthcare | 2.30% | — | — | |
| 14 | IDYA | Ideaya Biosciences INC | Stock-Other | 2.30% | — | -19.18% | |
| 15 | ACIU | AC Immune SA | Stock-Other | 2.14% | -0.36% | -23.55% | |
| 16 | RCUS | Arcus Biosciences INC | Stock-Other | 1.98% | — | -31.83% | |
| 17 | LXRX | Lexicon Pharmaceuticals INC | Stock-Other | 1.85% | — | -23.43% | |
| 18 | KURA | Kura Oncology INC | Stock-Other | 1.73% | -0.82% | +31.24% | |
| 19 | ✓ | Ikena Oncology INC | Stock-Other | 1.69% | — | — | |
| 20 | FDMT | 4d Molecular Therapeutics In | Stock-Other | 1.68% | -0.32% | -6.78% | |
| 21 | CGEM | Cullinan Therapeutics INC | Stock-Other | 1.64% | +0.60% | — | |
| 22 | CTMX | Cytomx Therapeutics INC | Stock-Other | 1.62% | — | — | |
| 23 | ✓ | Molecular Templates Inc | Stock-Other | 1.36% | — | +33.28% | |
| 24 | SPRO | Spero Therapeutics INC | Stock-Other | 1.18% | — | -4.69% | |
| 25 | GLYCEUR | Glycomimetics INC | Stock-Other | 1.08% | — | — | |
| 26 | RYI | Viracta Therapeutics INC | Stock-Other | 1.07% | — | — | |
| 27 | ✓ | Veralto CORP | Stock-Other | 1.06% | — | +2.68% | |
| 28 | INFIQ | Infinity Pharmaceuticals INC | Stock-Other | 1.02% | — | -51.89% | |
| 29 | OVID | Ovid Therapeutics INC | Stock-Other | 0.97% | — | +41.92% | |
| 30 | ANAB | Anaptysbio INC | Stock-Other | 0.96% | — | — | |
| 31 | TOCAEUR | Forte Biosciences INC | Stock-Other | 0.92% | — | — | |
| 32 | ✓ | Stock-Other | 0.78% | — | — | ||
| 33 | CTIC1USD | Cti Biopharma CORP | Stock-Other | 0.76% | — | — | |
| 34 | STRO | Sutro Biopharma, Inc. | Stock-Other | 0.71% | — | -55.41% | |
| 35 | IMVT | Immunovant INC | Stock-Other | 0.69% | — | +122.41% | |
| 36 | CFRXUSD | Contrafect CORP | Stock-Other | 0.69% | — | +138.27% | |
| 37 | 2JQ | Gritstone Bio INC | Stock-Other | 0.66% | — | -30.95% | |
| 38 | SLN | Silence Therapeutics Plc-adr | Stock-Other | 0.59% | — | — | |
| 39 | ✓ | Angion BioMedica Corp | Stock-Other | 0.59% | — | — | |
| 40 | PIRSEUR | Pieris Pharmaceuticals INC | Stock-Other | 0.53% | — | — | |
| 41 | REPL | Replimune Group INC | Stock-Other | 0.53% | — | — | |
| 42 | CALAEUR | Calithera Biosciences INC | Stock-Other | 0.51% | — | +27.64% | |
| 43 | COGT | Cogent Biosciences INC | Stock-Other | 0.50% | — | — | |
| 44 | MEIPUSD | Lite Strategy INC | Stock-Other | 0.46% | — | -11.39% | |
| 45 | ELDN | Eledon Pharmaceuticals INC | Stock-Other | 0.45% | +0.30% | — | |
| 46 | GNCAQ | Genocea Biosciences INC | Stock-Other | 0.41% | — | — | |
| 47 | SELBUSD | Cartesian Therapeutics INC | Stock-Other | 0.40% | — | -27.99% | |
| 48 | ✓ | Amarin Corp PLC | Stock-Other | 0.40% | — | -84.05% | |
| 49 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.37% | — | — | |
| 50 | CRVS | Corvus Pharmaceuticals INC | Stock-Other | 0.37% | — | +66.15% |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | FPRX | Five Prime Therapeutics INC | +8.3% | +510.26% | Add |
| 2 | ARGX | Argenx Se - Adr | +2.5% | +395.43% | Add |
| 3 | ✓ | Merus N V | +1.7% | +25.48% | Add |
| 4 | EPIEUR | Essa Pharma INC | +1.4% | -21.51% | Trim |
| 5 | RVMD | Revolution Medicines INC | +0.8% | +6.32% | Add |
| 6 | ✓ | Molecular Templates Inc | +0.6% | +33.28% | Add |
| 7 | OVID | Ovid Therapeutics INC | +0.6% | +41.92% | Add |
| 8 | IDYA | Ideaya Biosciences INC | +0.5% | -19.18% | Trim |
| 9 | PTGX | Protagonist Therapeutics INC | +0.5% | -7.35% | Trim |
| 10 | LXRX | Lexicon Pharmaceuticals INC | +0.4% | -23.43% | Trim |
| 11 | CFRXUSD | Contrafect CORP | +0.4% | +138.27% | Add |
| 12 | RPTX | Repare Therapeutics INC | +0.3% | +25.24% | Add |
| 13 | 2JQ | Gritstone Bio INC | +0.2% | -30.95% | Trim |
| 14 | XENE | Xenon Pharmaceuticals INC | +0.2% | -0.50% | Trim |
| 15 | CTMX | Cytomx Therapeutics INC | +0.2% | — | Unchanged |
| 16 | ACIU | AC Immune SA | +0.1% | -23.55% | Trim |
| 17 | KURA | Kura Oncology INC | +0.1% | +31.24% | Add |
| 18 | ✓ | Therapeutics Acquisition Cor | -0.2% | -19.14% | Trim |
| 19 | IMVT | Immunovant INC | -0.2% | +122.41% | Add |
| 20 | GLYCEUR | Glycomimetics INC | -0.3% | — | Unchanged |
| 21 | CALAEUR | Calithera Biosciences INC | -0.3% | +27.64% | Add |
| 22 | INFIQ | Infinity Pharmaceuticals INC | -0.4% | -51.89% | Trim |
| 23 | SPRO | Spero Therapeutics INC | -0.5% | -4.69% | Trim |
| 24 | SNDX | Syndax Pharmaceuticals INC | -0.6% | -81.39% | Trim |
| 25 | IONS | Ionis Pharmaceuticals INC | -0.7% | — | Unchanged |
| 26 | RCUS | Arcus Biosciences INC | -0.8% | -31.83% | Trim |
| 27 | STRO | Sutro Biopharma, Inc. | -0.9% | -55.41% | Trim |
| 28 | RLAY | Relay Therapeutics INC | -1.3% | -6.51% | Trim |
| 29 | ✓ | Amarin Corp PLC | -1.7% | -84.05% | Trim |
| 30 | XOMA | Xoma Royalty Corporation | -1.9% | -15.58% | Trim |
| 31 | KYMR | Kymera Therapeutics INC | -2.6% | — | Unchanged |
| 32 | OLMA | Olema Pharmaceuticals INC | -4.3% | — | Unchanged |
| 33 | CYTK | Cytokinetics INC | — | EXIT | Sold out |
| 34 | XNCR | Xencor INC | — | EXIT | Sold out |
| 35 | ALXO | Alx Oncology Holdings INC | — | EXIT | Sold out |
| 36 | ✓ | Ikena Oncology INC | — | NEW | New buy |
| 37 | CGEM | Cullinan Therapeutics INC | — | NEW | New buy |
| 38 | RYI | Viracta Therapeutics INC | — | NEW | New buy |
| 39 | ANAB | Anaptysbio INC | — | NEW | New buy |
| 40 | SLN | Silence Therapeutics Plc-adr | — | NEW | New buy |
| 41 | ✓ | Angion BioMedica Corp | — | NEW | New buy |
| 42 | REPL | Replimune Group INC | — | NEW | New buy |
| 43 | ELDN | Eledon Pharmaceuticals INC | — | NEW | New buy |
| 44 | ✓ | Novus Therapeutics Inc | — | EXIT | Sold out |
| 45 | ✓ | Gamida Cell LTD | — | EXIT | Sold out |
| 46 | VRDN | Viridian Therapeutics INC | — | NEW | New buy |
| 47 | ALRNEUR | Aileron Therapeutics INC | — | NEW | New buy |
| 48 | CRISEUR | Curis INC | — | EXIT | Sold out |
| 49 | ✓ | Research Alliance CORP Ii | — | NEW | New buy |
| 50 | PHAT | Phathom Pharmaceuticals INC | — | EXIT | Sold out |