13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
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CIK: 0001974915
申报总市值
US$42.8亿
US$42.8亿
76 檔
23.9%
在 Q4 2025 的 13F 官方备案中，Vestal Point Capital, LP 管理的美股投资组合规模来到 US$42.8亿，整体持股档数为 76 档。
Vestal Point Capital, LP 在 Q4 2025 进行了结构性的板块轮动与仓位换股。在开立 25 个全新仓位及加仓 24 档持股的同时，亦同步清仓 30 档并减仓 20 档标的。
在资产配置集中度方面，Vestal Point Capital, LP 的前 5 大核心持股（包含 ABVX, QQQ, ACLXGBX 等）合计占整体申报市值的 23.9%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ABVX | Abivax Sa-adr | 股票-其他 | 8.71% | +2.65% | +90.00% | |
| 2 | QQQ | Invesco Qqq Trust Series 1 | ETF-科技型 | 7.31% | — | — | |
| 3 | ACLXGBX | Arcellx Inc | 股票-其他 | 6.48% | — | +134.00% | |
| 4 | 430 | Terns Pharmaceuticals Inc | 股票-其他 | 6.18% | -1.47% | EXIT | |
| 5 | BMRN | Biomarin Pharmaceutical Inc | 股票-医疗保健 | 6.06% | +2.41% | +261.45% | |
| 6 | GMED | Globus Medical Inc - A | 股票-医疗保健 | 3.78% | +0.10% | +2.00% | |
| 7 | NRIX | Nurix Therapeutics Inc | 股票-其他 | 3.02% | +1.74% | +34.96% | |
| 8 | ALC | Alcon Inc. | 股票-医疗保健 | 2.96% | -0.91% | +0.45% | |
| 9 | DXCM | Dexcom Inc | 股票-医疗保健 | 2.88% | — | +96.15% | |
| 10 | MRK | Merck & Co. Inc. | 股票-医疗保健 | 2.77% | — | — | |
| 11 | TSHA | Taysha Gene Therapies Inc | 股票-其他 | 2.57% | +0.84% | +150.00% | |
| 12 | ABT | Abbott Laboratories | 股票-医疗保健 | 2.56% | +2.97% | NEW | |
| 13 | ✓ | Immatics NV | 股票-其他 | 2.19% | -0.24% | -3.54% | |
| 14 | TYRA | Tyra Biosciences Inc | 股票-其他 | 2.17% | -0.06% | EXIT | |
| 15 | BCAX | Bicara Therapeutics Inc | 股票-其他 | 2.05% | +0.62% | -29.90% | |
| 16 | ARWR | Arrowhead Pharmaceuticals In | 股票-医疗保健 | 2.03% | -0.99% | — | |
| 17 | ELVN | Enliven Therapeutics Inc | 股票-其他 | 2.01% | +1.18% | +230.17% | |
| 18 | IRON | Disc Medicine Inc | 股票-其他 | 1.98% | +1.40% | +47.00% | |
| 19 | JAZZ | Jazz Pharmaceuticals plc | 股票-医疗保健 | 1.68% | — | -42.00% | |
| 20 | DAWNGBX | Day One Biopharmaceuticals I | 股票-其他 | 1.65% | — | +94.39% | |
| 21 | LXEO | Lexeo Therapeutics Inc | 股票-其他 | 1.51% | -0.25% | +37.69% | |
| 22 | ANRO | Alto Neuroscience Inc | 股票-其他 | 1.50% | -0.82% | +161.58% | |
| 23 | APGE | Apogee Therapeutics Inc | 股票-其他 | 1.41% | -2.59% | EXIT | |
| 24 | OLMA | Olema Pharmaceuticals Inc | 股票-其他 | 1.40% | -0.06% | — | |
| 25 | AXSM | Axsome Therapeutics Inc | 股票-医疗保健 | 1.30% | — | +40.00% | |
| 26 | ASND | Ascendis Pharma A/S | 股票-其他 | 1.27% | -2.40% | EXIT | |
| 27 | RAPP | Rapport Therapeutics Inc | 股票-其他 | 1.14% | -0.55% | +16.84% | |
| 28 | SLDB | Solid Biosciences Inc | 股票-其他 | 1.12% | -0.51% | +95.46% | |
| 29 | CLDX | Celldex Therapeutics Inc | 股票-其他 | 1.08% | -1.09% | EXIT | |
| 30 | SRRK | Scholar Rock Holding CORP | 股票-其他 | 1.05% | -1.82% | EXIT | |
| 31 | 4XC1 | Kalvista Pharmaceuticals Inc | 股票-其他 | 1.04% | -1.04% | EXIT | |
| 32 | VERA | Vera Therapeutics Inc | 股票-其他 | 0.95% | -1.54% | EXIT | |
| 33 | XENE | Xenon Pharmaceuticals Inc | 股票-其他 | 0.91% | -0.05% | -45.45% | |
| 34 | LNTH | Lantheus Holdings Inc | 股票-医疗保健 | 0.81% | — | +111.76% | |
| 35 | RVMD | Revolution Medicines Inc | 股票-医疗保健 | 0.80% | -4.49% | -53.17% | |
| 36 | ZYME | Zymeworks Inc | 股票-其他 | 0.77% | — | -50.99% | |
| 37 | IMCR | Immunocore Holdings Plc-adr | 股票-其他 | 0.69% | -0.99% | — | |
| 38 | UPB | Upstream Bio Inc | 股票-其他 | 0.66% | — | — | |
| 39 | BBNX | Beta Bionics Inc | 股票-其他 | 0.62% | -0.03% | — | |
| 40 | ✓ | Crescent Biopharma Inc. | 股票-其他 | 0.60% | -0.08% | — | |
| 41 | BCRX | Biocryst Pharmaceuticals Inc | 股票-其他 | 0.60% | +0.07% | — | |
| 42 | PEN | Penumbra Inc | 股票-医疗保健 | 0.53% | — | — | |
| 43 | GERN | Geron CORP | 股票-其他 | 0.51% | -0.11% | EXIT | |
| 44 | RGEN | Repligen CORP | 股票-医疗保健 | 0.46% | -1.77% | -79.25% | |
| 45 | ZBH | Zimmer Biomet Holdings Inc | 股票-医疗保健 | 0.46% | +2.34% | — | |
| 46 | BMY | Bristol-myers Squibb Co | 股票-医疗保健 | 0.46% | -0.62% | — | |
| 47 | GLUE | Monte Rosa Therapeutics Inc | 股票-其他 | 0.41% | +0.94% | -3.13% | |
| 48 | FULC | Fulcrum Therapeutics Inc | 股票-其他 | 0.37% | -0.24% | EXIT | |
| 49 | SVRA | Savara Inc | 股票-其他 | 0.33% | -0.01% | -60.00% | |
| 50 | ✓ | Engene Holdings Inc | 股票-其他 | 0.32% | -0.41% | EXIT |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | ABVX | Abivax Sa-adr | +4.9% | +90.00% | 加仓 |
| 2 | BMRN | Biomarin Pharmaceutical Inc | +4% | +261.45% | 加仓 |
| 3 | ACLXGBX | Arcellx Inc | +1.9% | +134.00% | 加仓 |
| 4 | TSHA | Taysha Gene Therapies Inc | +1.8% | +150.00% | 加仓 |
| 5 | NRIX | Nurix Therapeutics Inc | +1.6% | +34.96% | 加仓 |
| 6 | ANRO | Alto Neuroscience Inc | +1.3% | +161.58% | 加仓 |
| 7 | ABT | Abbott Laboratories | +1.1% | +140.00% | 加仓 |
| 8 | ELVN | Enliven Therapeutics Inc | +0.9% | +230.17% | 加仓 |
| 9 | DXCM | Dexcom Inc | +0.9% | +96.15% | 加仓 |
| 10 | DAWNGBX | Day One Biopharmaceuticals I | +0.8% | +94.39% | 加仓 |
| 11 | APGE | Apogee Therapeutics Inc | +0.7% | +29.41% | 加仓 |
| 12 | TYRA | Tyra Biosciences Inc | +0.6% | — | 不变 |
| 13 | 4XC1 | Kalvista Pharmaceuticals Inc | +0.6% | +152.00% | 加仓 |
| 14 | GMED | Globus Medical Inc - A | +0.6% | +2.00% | 加仓 |
| 15 | LXEO | Lexeo Therapeutics Inc | +0.5% | +37.69% | 加仓 |
| 16 | IRON | Disc Medicine Inc | +0.5% | +47.00% | 加仓 |
| 17 | AXSM | Axsome Therapeutics Inc | +0.5% | +40.00% | 加仓 |
| 18 | LNTH | Lantheus Holdings Inc | +0.4% | +111.76% | 加仓 |
| 19 | SLDB | Solid Biosciences Inc | +0.3% | +95.46% | 加仓 |
| 20 | ✓ | Engene Holdings Inc | +0.2% | +185.14% | 加仓 |
| 21 | GLUE | Monte Rosa Therapeutics Inc | +0.1% | -3.13% | 减仓 |
| 22 | BBNX | Beta Bionics Inc | +0.1% | — | 不变 |
| 23 | AGIO | Agios Pharmaceuticals Inc | +0.1% | +155.91% | 加仓 |
| 24 | MYGN | Myriad Genetics Inc | +0.1% | +103.83% | 加仓 |
| 25 | PASG | Passage Bio Inc | 0% | — | 不变 |
| 26 | NVCR | NovoCure Limited | — | +31.25% | 加仓 |
| 27 | TENX | Tenax Therapeutics Inc | — | — | 不变 |
| 28 | MGNX | Macrogenics Inc | — | — | 不变 |
| 29 | OKUR | Onkure Therapeutics Inc-a | 0% | — | 不变 |
| 30 | VERA | Vera Therapeutics Inc | -0.1% | -27.63% | 减仓 |
| 31 | ✓ | Nyxoah S A | -0.1% | -0.04% | 减仓 |
| 32 | FATE | Fate Therapeutics Inc | -0.1% | -31.41% | 减仓 |
| 33 | ALEC | Alector Inc | -0.1% | -22.96% | 减仓 |
| 34 | VYGR | Voyager Therapeutics Inc | -0.1% | — | 不变 |
| 35 | RAPP | Rapport Therapeutics Inc | -0.1% | +16.84% | 加仓 |
| 36 | ✓ | Immatics NV | -0.3% | -3.54% | 减仓 |
| 37 | SVRA | Savara Inc | -0.3% | -60.00% | 减仓 |
| 38 | CLDX | Celldex Therapeutics Inc | -0.3% | -3.32% | 减仓 |
| 39 | RVMD | Revolution Medicines Inc | -0.5% | -53.17% | 减仓 |
| 40 | GERN | Geron CORP | -0.6% | -34.28% | 减仓 |
| 41 | ZYME | Zymeworks Inc | -0.6% | -50.99% | 减仓 |
| 42 | ALC | Alcon Inc. | -0.7% | +0.45% | 加仓 |
| 43 | BDTX | Black Diamond Therapeutics I | -0.9% | -84.32% | 减仓 |
| 44 | XENE | Xenon Pharmaceuticals Inc | -1.1% | -45.45% | 减仓 |
| 45 | JAZZ | Jazz Pharmaceuticals plc | -1.3% | -42.00% | 减仓 |
| 46 | SRRK | Scholar Rock Holding CORP | -1.5% | -53.33% | 减仓 |
| 47 | DYN | Dyne Therapeutics Inc | -1.5% | -95.68% | 减仓 |
| 48 | BCAX | Bicara Therapeutics Inc | -1.6% | -29.90% | 减仓 |
| 49 | RGEN | Repligen CORP | -2% | -79.25% | 减仓 |
| 50 | ASND | Ascendis Pharma A/S | -4.1% | -70.83% | 减仓 |
根据 SEC 官方 Form 13F 申报备案，Vestal Point Capital, LP 在 Q4 2025 季度的美股持仓总市值约为 US$42.8亿，共申报了 76 个公开持股仓位。
在 Q4 2025 季度，Vestal Point Capital, LP 按市值排列的前三大核心持股分别为：ABVX (8.7%)、QQQ (7.3%)、ACLXGBX (6.5%)。其中最大持股仓位 ABVX 占据整体投资组合约 8.7% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
QQQ
市值: US$2.2亿
本季最大获利了结 / 清仓标的
AM6
前期市值: US$7683.0万
在 Q4 2025 季度中，Vestal Point Capital, LP 共进行了 99 项持仓异动，包含新建仓 25 个仓位、加仓 24 个仓位、减仓 20 个仓位以及清仓 30 个仓位。 其中最大新建仓标的为 QQQ。 本季清仓仓位包含 AM6。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。