13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
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CIK: 0001631134
申报总市值
US$19.3亿
US$19.3亿
60 檔
29.0%
在 Q4 2024 的 13F 官方备案中，Sofinnova Investments, Inc. 管理的美股投资组合规模来到 US$19.3亿，整体持股档数为 60 档。
Sofinnova Investments, Inc. 在 Q4 2024 进行了结构性的板块轮动与仓位换股。在开立 17 个全新仓位及加仓 11 档持股的同时，亦同步清仓 15 档并减仓 21 档标的。
在资产配置集中度方面，Sofinnova Investments, Inc. 的前 5 大核心持股（包含 NTRA, VERA, GILD 等）合计占整体申报市值的 29.0%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | NTRA | Natera Inc | 股票-医疗保健 | 17.88% | +9.98% | — | |
| 2 | VERA | Vera Therapeutics Inc | 股票-其他 | 8.61% | +1.93% | — | |
| 3 | GILD | Gilead Sciences Inc | 股票-医疗保健 | 5.21% | +2.24% | NEW | |
| 4 | ABBV | Abbvie Inc | 股票-医疗保健 | 4.65% | — | — | |
| 5 | JAZZ | Jazz Pharmaceuticals plc | 股票-医疗保健 | 4.52% | +0.25% | +167.39% | |
| 6 | SRPT | Sarepta Therapeutics Inc | 股票-医疗保健 | 3.80% | — | — | |
| 7 | AXSM | Axsome Therapeutics Inc | 股票-医疗保健 | 3.65% | -0.62% | +11.75% | |
| 8 | AVBP | Arrivent Biopharma Inc | 股票-其他 | 3.29% | +1.56% | — | |
| 9 | AZNN | Astrazeneca Plc-spons Adr | 股票-其他 | 3.11% | — | -19.53% | |
| 10 | SYK | Stryker CORP | 股票-医疗保健 | 3.04% | -0.56% | EXIT | |
| 11 | REPL | Replimune Group Inc | 股票-其他 | 2.78% | -0.30% | EXIT | |
| 12 | INCY | Incyte CORP | 股票-医疗保健 | 2.64% | — | -26.59% | |
| 13 | RAPP | Rapport Therapeutics Inc | 股票-其他 | 2.58% | +1.84% | — | |
| 14 | SLNOEUR | Soleno Therapeutics Inc | 股票-其他 | 2.48% | -0.02% | EXIT | |
| 15 | BSX | Boston Scientific CORP | 股票-医疗保健 | 2.25% | — | +155.17% | |
| 16 | IDYA | Ideaya Biosciences Inc | 股票-其他 | 2.00% | +0.35% | -38.89% | |
| 17 | ALNY | Alnylam Pharmaceuticals Inc | 股票-医疗保健 | 1.89% | — | — | |
| 18 | ALKS | Alkermes plc | 股票-医疗保健 | 1.87% | — | — | |
| 19 | DYN | Dyne Therapeutics Inc | 股票-其他 | 1.84% | +0.77% | +38.78% | |
| 20 | DXCM | Dexcom Inc | 股票-医疗保健 | 1.64% | -0.94% | EXIT | |
| 21 | RYTM | Rhythm Pharmaceuticals Inc | 股票-其他 | 1.62% | +0.85% | +43.64% | |
| 22 | GMED | Globus Medical Inc - A | 股票-医疗保健 | 1.47% | +0.82% | NEW | |
| 23 | ISRG | Intuitive Surgical Inc | 股票-医疗保健 | 1.44% | +0.82% | NEW | |
| 24 | INSM | Insmed Inc | 股票-医疗保健 | 1.29% | -1.28% | -10.49% | |
| 25 | YMABUSD | Y-mabs Therapeutics Inc | 股票-其他 | 1.25% | — | — | |
| 26 | SVRA | Savara Inc | 股票-其他 | 1.22% | +0.04% | -3.38% | |
| 27 | JANX | Janux Therapeutics Inc | 股票-其他 | 0.99% | — | +53.71% | |
| 28 | BIOA | Bioage Labs Inc | 股票-其他 | 0.97% | +1.39% | — | |
| 29 | ✓ | Inozyme Pharma Inc | 股票-其他 | 0.86% | — | — | |
| 30 | LLY | Eli Lilly & Co | 股票-医疗保健 | 0.81% | — | — | |
| 31 | EWTX | Edgewise Therapeutics Inc | 股票-其他 | 0.78% | +0.34% | +4.68% | |
| 32 | PHVS | Pharvaris N.V. | 股票-其他 | 0.78% | +0.70% | -6.59% | |
| 33 | ✓ | 股票-其他 | 0.73% | — | — | ||
| 34 | NARIUSD | Inari Medical Inc | 股票-其他 | 0.67% | — | +99.78% | |
| 35 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 0.63% | — | -16.31% | |
| 36 | INBX | Inhibrx Biosciences Inc | 股票-其他 | 0.59% | +0.44% | -1.66% | |
| 37 | IMNM | Immunome Inc | 股票-其他 | 0.58% | +0.47% | +10.35% | |
| 38 | COGT | Cogent Biosciences Inc | 股票-其他 | 0.47% | -1.02% | -63.66% | |
| 39 | ACHV | Achieve Life Sciences Inc | 股票-其他 | 0.33% | — | -13.71% | |
| 40 | ERAS | Erasca Inc | 股票-其他 | 0.33% | — | -2.54% | |
| 41 | ✓ | Establishment Labs Holdings In | 股票-其他 | 0.32% | -0.07% | EXIT | |
| 42 | AVTR | Avantor Inc | 股票-医疗保健 | 0.31% | — | — | |
| 43 | EW | Edwards Lifesciences CORP | 股票-医疗保健 | 0.22% | — | -80.29% | |
| 44 | EXK | Exact Sciences CORP | 股票-原材料 | 0.21% | — | +38.27% | |
| 45 | ✓ | Immatics NV | 股票-其他 | 0.18% | +0.56% | -11.11% | |
| 46 | DHR | Danaher CORP | 股票-医疗保健 | 0.17% | — | — | |
| 47 | NXTCEUR | Nextcure Inc | 股票-其他 | 0.15% | — | — | |
| 48 | ANAB | Anaptysbio Inc | 股票-其他 | 0.13% | +1.20% | — | |
| 49 | KROS | Keros Therapeutics Inc | 股票-其他 | 0.11% | — | — | |
| 50 | BOLT1EUR | Bolt Biotherapeutics Inc | 股票-其他 | 0.11% | — | — |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | GILD | Gilead Sciences Inc | +5.2% | NEW | 新建仓 |
| 2 | ABBV | Abbvie Inc | +4.7% | NEW | 新建仓 |
| 3 | SRPT | Sarepta Therapeutics Inc | +3.8% | NEW | 新建仓 |
| 4 | SYK | Stryker CORP | +3% | NEW | 新建仓 |
| 5 | JAZZ | Jazz Pharmaceuticals plc | +2.9% | +167.39% | 加仓 |
| 6 | REPL | Replimune Group Inc | +2.7% | +6442.69% | 加仓 |
| 7 | NTRA | Natera Inc | +2.3% | — | 不变 |
| 8 | ALNY | Alnylam Pharmaceuticals Inc | +1.9% | NEW | 新建仓 |
| 9 | ALKS | Alkermes plc | +1.9% | NEW | 新建仓 |
| 10 | DXCM | Dexcom Inc | +1.6% | NEW | 新建仓 |
| 11 | GMED | Globus Medical Inc - A | +1.5% | NEW | 新建仓 |
| 12 | ISRG | Intuitive Surgical Inc | +1.4% | NEW | 新建仓 |
| 13 | BSX | Boston Scientific CORP | +1.4% | +155.17% | 加仓 |
| 14 | LLY | Eli Lilly & Co | +0.8% | NEW | 新建仓 |
| 15 | RYTM | Rhythm Pharmaceuticals Inc | +0.5% | +43.64% | 加仓 |
| 16 | JANX | Janux Therapeutics Inc | +0.4% | +53.71% | 加仓 |
| 17 | NARIUSD | Inari Medical Inc | +0.4% | +99.78% | 加仓 |
| 18 | AVTR | Avantor Inc | +0.3% | NEW | 新建仓 |
| 19 | DHR | Danaher CORP | +0.2% | NEW | 新建仓 |
| 20 | AVBP | Arrivent Biopharma Inc | +0.1% | — | 不变 |
| 21 | ANAB | Anaptysbio Inc | +0.1% | NEW | 新建仓 |
| 22 | ✓ | +0.1% | — | 不变 | |
| 23 | KROS | Keros Therapeutics Inc | +0.1% | NEW | 新建仓 |
| 24 | ICUI | Icu Medical Inc | +0.1% | NEW | 新建仓 |
| 25 | ELVN | Enliven Therapeutics Inc | +0.1% | NEW | 新建仓 |
| 26 | TVTX | Travere Therapeutics Inc | 0% | NEW | 新建仓 |
| 27 | EXK | Exact Sciences CORP | 0% | +38.27% | 加仓 |
| 28 | ✓ | Ikena Oncology Inc | — | — | 不变 |
| 29 | LUNG | Pulmonx CORP | 0% | -1.58% | 减仓 |
| 30 | VIR | Vir Biotechnology Inc | 0% | -11.69% | 减仓 |
| 31 | BOLT1EUR | Bolt Biotherapeutics Inc | 0% | — | 不变 |
| 32 | EWTX | Edgewise Therapeutics Inc | 0% | +4.68% | 加仓 |
| 33 | IRON | Disc Medicine Inc | -0.1% | -44.98% | 减仓 |
| 34 | CATBUSD | Astria Therapeutics Inc | -0.1% | EXIT | 清仓 |
| 35 | ✓ | Immatics N.v | -0.1% | EXIT | 清仓 |
| 36 | ERAS | Erasca Inc | -0.1% | -2.54% | 减仓 |
| 37 | RNAGBP | Avidity Biosciences Inc | -0.1% | -54.75% | 减仓 |
| 38 | INBX | Inhibrx Biosciences Inc | -0.1% | -1.66% | 减仓 |
| 39 | GPCR | Structure Therapeutics Inc | -0.1% | -46.14% | 减仓 |
| 40 | PHVS | Pharvaris N.V. | -0.1% | -6.59% | 减仓 |
| 41 | AXSM | Axsome Therapeutics Inc | -0.1% | +11.75% | 加仓 |
| 42 | CATX | Perspective Therapeutics Inc | -0.1% | EXIT | 清仓 |
| 43 | NXTCEUR | Nextcure Inc | -0.1% | — | 不变 |
| 44 | ✓ | Immatics NV | -0.2% | -11.11% | 减仓 |
| 45 | BDX | Becton Dickinson And Co | -0.2% | -67.41% | 减仓 |
| 46 | IMNM | Immunome Inc | -0.2% | +10.35% | 加仓 |
| 47 | ACHV | Achieve Life Sciences Inc | -0.2% | -13.71% | 减仓 |
| 48 | TMO | Thermo Fisher Scientific Inc | -0.3% | EXIT | 清仓 |
| 49 | ✓ | Establishment Labs Holdings In | -0.3% | -47.48% | 减仓 |
| 50 | DYN | Dyne Therapeutics Inc | -0.4% | +38.78% | 加仓 |
根据 SEC 官方 Form 13F 申报备案，Sofinnova Investments, Inc. 在 Q4 2024 季度的美股持仓总市值约为 US$19.3亿，共申报了 60 个公开持股仓位。
在 Q4 2024 季度，Sofinnova Investments, Inc. 按市值排列的前三大核心持股分别为：NTRA (17.9%)、VERA (8.6%)、GILD (5.2%)。其中最大持股仓位 NTRA 占据整体投资组合约 17.9% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
GILD
市值: US$7151.5万
本季最大获利了结 / 清仓标的
NVO
前期市值: US$8648.4万
在 Q4 2024 季度中，Sofinnova Investments, Inc. 共进行了 64 项持仓异动，包含新建仓 17 个仓位、加仓 11 个仓位、减仓 21 个仓位以及清仓 15 个仓位。 其中最大新建仓标的为 GILD。 本季清仓仓位包含 NVO。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。