13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
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CIK: 0001224962
申报总市值
US$66.6亿
US$66.6亿
84 檔
16.6%
截至 Q2 2025 季度末，Perceptive Advisors LLC 的美股持仓估值约为 US$66.6亿，全数申报仓位共有 84 档。
在 Q2 2025，Perceptive Advisors LLC 展现出较为审慎的避险与获利了结姿态。本季共减仓 33 个仓位并完全清仓 23 档持股，调降曝光的仓位数量高于加仓动作。
在资产配置集中度方面，Perceptive Advisors LLC 的前 5 大核心持股（包含 VRNA, ASND, ACLXGBX 等）合计占整体申报市值的 16.6%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | VRNA | Verona Pharma PLC - Adr | 股票-其他 | 19.31% | — | -16.09% | |
| 2 | ASND | Ascendis Pharma A/S | 股票-其他 | 6.17% | -6.84% | EXIT | |
| 3 | ACLXGBX | Arcellx Inc | 股票-其他 | 6.05% | — | -15.32% | |
| 4 | RYTM | Rhythm Pharmaceuticals Inc | 股票-其他 | 5.67% | +0.28% | -5.11% | |
| 5 | NUVL | Nuvalent Inc-a | 股票-其他 | 3.89% | -0.23% | -15.84% | |
| 6 | AORT | Artivion Inc | 股票-其他 | 3.22% | -0.58% | — | |
| 7 | MGTX | MeiraGTx Holdings plc | 股票-其他 | 3.05% | +0.44% | +0.36% | |
| 8 | INSM | Insmed Inc | 股票-医疗保健 | 2.43% | — | +27.68% | |
| 9 | EWTX | Edgewise Therapeutics Inc | 股票-其他 | 2.26% | -0.05% | -34.16% | |
| 10 | PTGX | Protagonist Therapeutics Inc | 股票-其他 | 2.20% | -0.73% | -1.54% | |
| 11 | SLDB | Solid Biosciences Inc | 股票-其他 | 2.15% | +0.11% | — | |
| 12 | APGE | Apogee Therapeutics Inc | 股票-其他 | 1.90% | +0.08% | +5.29% | |
| 13 | AMLX | Amylyx Pharmaceuticals Inc | 股票-其他 | 1.88% | — | +0.36% | |
| 14 | ✓ | Immatics NV | 股票-其他 | 1.87% | -0.42% | — | |
| 15 | AKRO | Akero Therapeutics Inc | 股票-其他 | 1.81% | — | +15.50% | |
| 16 | OMDA | Omada Health Inc | 股票-其他 | 1.65% | +0.07% | — | |
| 17 | AM6 | Amicus Therapeutics Inc | 股票-其他 | 1.57% | — | -65.46% | |
| 18 | ROIV | Roivant Sciences Ltd. | 股票-医疗保健 | 1.39% | -0.18% | — | |
| 19 | ✓ | Merus N V | 股票-其他 | 1.38% | — | +2.56% | |
| 20 | SLNOEUR | Soleno Therapeutics Inc | 股票-其他 | 1.34% | — | -71.43% | |
| 21 | CATBUSD | Astria Therapeutics Inc | 股票-其他 | 1.29% | — | — | |
| 22 | IMVT | Immunovant Inc | 股票-其他 | 1.27% | +0.01% | -24.83% | |
| 23 | NBIX | Neurocrine Biosciences Inc | 股票-医疗保健 | 1.19% | -0.17% | EXIT | |
| 24 | PRAX | Praxis Precision Medicines I | 股票-其他 | 1.17% | -2.59% | -23.24% | |
| 25 | BSX | Boston Scientific CORP | 股票-医疗保健 | 1.11% | +0.16% | NEW | |
| 26 | CAI | Caris Life Sciences Inc | 股票-其他 | 1.09% | — | — | |
| 27 | XBI | Ss Spdr S&p Biotech ETF | ETF-科技型 | 0.92% | +0.71% | NEW | |
| 28 | ISRG | Intuitive Surgical Inc | 股票-医疗保健 | 0.91% | -0.46% | +11.08% | |
| 29 | ADMA | Adma Biologics Inc | 股票-医疗保健 | 0.88% | -0.07% | -5.08% | |
| 30 | BBNX | Beta Bionics Inc | 股票-其他 | 0.86% | +0.04% | — | |
| 31 | SYRE | Spyre Therapeutics Inc | 股票-其他 | 0.85% | +2.03% | -33.88% | |
| 32 | EOLS | Evolus Inc | 股票-其他 | 0.85% | +0.16% | -40.06% | |
| 33 | CELC | Celcuity Inc | 股票-其他 | 0.81% | -1.95% | -30.86% | |
| 34 | DYN | Dyne Therapeutics Inc | 股票-其他 | 0.79% | -0.75% | -2.85% | |
| 35 | SION | Sionna Therapeutics Inc | 股票-其他 | 0.78% | +0.08% | -2.80% | |
| 36 | AXSM | Axsome Therapeutics Inc | 股票-医疗保健 | 0.77% | -0.06% | -44.09% | |
| 37 | RGEN | Repligen CORP | 股票-医疗保健 | 0.77% | -0.14% | +27.89% | |
| 38 | PODD | Insulet CORP | 股票-医疗保健 | 0.70% | — | -15.66% | |
| 39 | OM | Outset Medical Inc | 股票-其他 | 0.59% | -0.01% | — | |
| 40 | ZYME | Zymeworks Inc | 股票-其他 | 0.59% | -0.08% | -31.61% | |
| 41 | CTMX | Cytomx Therapeutics Inc | 股票-其他 | 0.59% | -0.34% | — | |
| 42 | ALDX | Aldeyra Therapeutics Inc | 股票-其他 | 0.58% | — | -56.32% | |
| 43 | CRL | Charles River Laboratories | 股票-医疗保健 | 0.56% | +0.48% | NEW | |
| 44 | 260 | Centessa Pharmaceuticals-adr | 股票-其他 | 0.56% | -4.08% | EXIT | |
| 45 | INBX | Inhibrx Biosciences Inc | 股票-其他 | 0.52% | -0.05% | -8.10% | |
| 46 | ADGM | Adagio Medical Holdings Inc | 股票-其他 | 0.48% | -0.12% | +0.65% | |
| 47 | NRIX | Nurix Therapeutics Inc | 股票-其他 | 0.46% | +0.45% | +268.67% | |
| 48 | TVTX | Travere Therapeutics Inc | 股票-其他 | 0.46% | +0.80% | — | |
| 49 | OBIO | Orchestra Biomed Holdings In | 股票-其他 | 0.46% | -0.09% | — | |
| 50 | DRUG | Bright Minds Biosciences Inc | 股票-其他 | 0.41% | -0.54% | EXIT |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | ASND | Ascendis Pharma A/S | +6.2% | NEW | 新建仓 |
| 2 | VRNA | Verona Pharma PLC - Adr | +4.6% | -16.09% | 减仓 |
| 3 | OMDA | Omada Health Inc | +1.7% | NEW | 新建仓 |
| 4 | ROIV | Roivant Sciences Ltd. | +1.4% | NEW | 新建仓 |
| 5 | CAI | Caris Life Sciences Inc | +1.1% | NEW | 新建仓 |
| 6 | INSM | Insmed Inc | +1.1% | +27.68% | 加仓 |
| 7 | XBI | Ss Spdr S&p Biotech ETF | +0.9% | NEW | 新建仓 |
| 8 | AMLX | Amylyx Pharmaceuticals Inc | +0.9% | +0.36% | 加仓 |
| 9 | RYTM | Rhythm Pharmaceuticals Inc | +0.9% | -5.11% | 减仓 |
| 10 | NBIX | Neurocrine Biosciences Inc | +0.8% | +154.92% | 加仓 |
| 11 | AORT | Artivion Inc | +0.8% | — | 不变 |
| 12 | AKRO | Akero Therapeutics Inc | +0.7% | +15.50% | 加仓 |
| 13 | BSX | Boston Scientific CORP | +0.7% | +115.38% | 加仓 |
| 14 | CTMX | Cytomx Therapeutics Inc | +0.6% | NEW | 新建仓 |
| 15 | SLDB | Solid Biosciences Inc | +0.6% | — | 不变 |
| 16 | CRL | Charles River Laboratories | +0.6% | NEW | 新建仓 |
| 17 | TVTX | Travere Therapeutics Inc | +0.5% | NEW | 新建仓 |
| 18 | APGE | Apogee Therapeutics Inc | +0.4% | +5.29% | 加仓 |
| 19 | ✓ | Immatics NV | +0.4% | — | 不变 |
| 20 | RARE | Ultragenyx Pharmaceutical In | +0.4% | NEW | 新建仓 |
| 21 | ✓ | Merus N V | +0.4% | +2.56% | 加仓 |
| 22 | KYMR | Kymera Therapeutics Inc | +0.3% | NEW | 新建仓 |
| 23 | NRIX | Nurix Therapeutics Inc | +0.3% | +268.67% | 加仓 |
| 24 | PTGX | Protagonist Therapeutics Inc | +0.3% | -1.54% | 减仓 |
| 25 | SION | Sionna Therapeutics Inc | +0.3% | -2.80% | 减仓 |
| 26 | PEN | Penumbra Inc | +0.3% | NEW | 新建仓 |
| 27 | CAPR | Capricor Therapeutics Inc | +0.3% | NEW | 新建仓 |
| 28 | ✓ | Crescent Biopharma Inc. | +0.3% | NEW | 新建仓 |
| 29 | OM | Outset Medical Inc | +0.3% | — | 不变 |
| 30 | CRVS | Corvus Pharmaceuticals Inc | +0.2% | NEW | 新建仓 |
| 31 | SEPN | Septerna Inc | +0.2% | NEW | 新建仓 |
| 32 | ADGM | Adagio Medical Holdings Inc | +0.2% | +0.65% | 加仓 |
| 33 | ISRG | Intuitive Surgical Inc | +0.2% | +11.08% | 加仓 |
| 34 | GMED | Globus Medical Inc - A | +0.2% | NEW | 新建仓 |
| 35 | ✓ | Envveno Medical CORP | +0.2% | NEW | 新建仓 |
| 36 | RGEN | Repligen CORP | +0.2% | +27.89% | 加仓 |
| 37 | BBNX | Beta Bionics Inc | +0.2% | — | 不变 |
| 38 | LYRA | Lyra Therapeutics Inc | +0.1% | NEW | 新建仓 |
| 39 | CATBUSD | Astria Therapeutics Inc | +0.1% | — | 不变 |
| 40 | RAPT | Rapt Therapeutics Inc | +0.1% | NEW | 新建仓 |
| 41 | MGTX | MeiraGTx Holdings plc | 0% | +0.36% | 加仓 |
| 42 | TRIB | Trinity Biotech Plc-spon Adr | 0% | NEW | 新建仓 |
| 43 | PODD | Insulet CORP | 0% | -15.66% | 减仓 |
| 44 | FBRX | Forte Biosciences Inc | 0% | NEW | 新建仓 |
| 45 | SCPH | Scpharmaceuticals Inc | 0% | — | 不变 |
| 46 | ✓ | Athira Pharma Inc | 0% | — | 不变 |
| 47 | ✓ | Helix Acquisition CORP Ii | — | — | 不变 |
| 48 | IRD | Opus Genetics Inc | — | — | 不变 |
| 49 | APYX | Apyx Medical CORP | — | — | 不变 |
| 50 | LXEO | Lexeo Therapeutics Inc | — | — | 不变 |
根据 SEC 官方 Form 13F 申报备案，Perceptive Advisors LLC 在 Q2 2025 季度的美股持仓总市值约为 US$66.6亿，共申报了 84 个公开持股仓位。
在 Q2 2025 季度，Perceptive Advisors LLC 按市值排列的前三大核心持股分别为：VRNA (19.3%)、ASND (6.2%)、ACLXGBX (6.0%)。其中最大持股仓位 VRNA 占据整体投资组合约 19.3% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
ASND
市值: US$1.7亿
本季最大获利了结 / 清仓标的
ITCIEUR
前期市值: US$1.0亿
在 Q2 2025 季度中，Perceptive Advisors LLC 共进行了 89 项持仓异动，包含新建仓 21 个仓位、加仓 12 个仓位、减仓 33 个仓位以及清仓 23 个仓位。 其中最大新建仓标的为 ASND。 本季清仓仓位包含 ITCIEUR。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。