13F 申報指南13F 觀念全攻略
什麼是 SEC Form 13F 申報？美股機構大戶持股全攻略
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
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CIK: 0001816307
申報總市值
US$9.6億
US$9.6億
68 檔
22.7%
在 Q4 2025 的 13F 官方備案中，Silverarc Capital Management, LLC 管理的美股投資組合規模來到 US$9.6億，整體持股檔數為 68 檔。
從 Q4 2025 申報觀察，Silverarc Capital Management, LLC 採取防禦導向的調倉策略，本季減碼 27 檔個股並出清 35 檔部位，顯示機構在該時期進行風險控制與流動性回收。
在資產配置集中度方面，Silverarc Capital Management, LLC 的前 5 大核心持股（包含 ABVX, COGT, URGN 等）合計佔整體申報市值的 22.7%，反映機構在主要關鍵部位上的權重分佈。
| # | 代號 | 標的名稱 | 資產子類別 | 佔比 | 佔比變動 | 持倉量變化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ABVX | Abivax Sa-adr | 股票-其他 | 7.91% | -1.09% | -21.77% | |
| 2 | COGT | Cogent Biosciences Inc | 股票-其他 | 6.14% | -0.01% | +52.78% | |
| 3 | URGN | UroGen Pharma Ltd. | 股票-其他 | 5.66% | +2.22% | +10.24% | |
| 4 | 4XC1 | Kalvista Pharmaceuticals Inc | 股票-其他 | 5.44% | -5.91% | EXIT | |
| 5 | CELC | Celcuity Inc | 股票-其他 | 5.20% | +1.28% | +322.99% | |
| 6 | NUVL | Nuvalent Inc-a | 股票-其他 | 4.35% | -3.71% | EXIT | |
| 7 | DNTH | Dianthus Therapeutics Inc | 股票-其他 | 4.29% | -1.66% | +11.14% | |
| 8 | KOD | Kodiak Sciences Inc | 股票-其他 | 3.97% | -1.65% | +2.31% | |
| 9 | PRAX | Praxis Precision Medicines I | 股票-其他 | 3.38% | -0.06% | +61.03% | |
| 10 | IMNM | Immunome Inc | 股票-其他 | 3.36% | +0.31% | — | |
| 11 | GUTS | Fractyl Health Inc | 股票-其他 | 3.01% | +0.06% | -7.17% | |
| 12 | ✓ | Uniqure NV | 股票-其他 | 2.40% | -0.83% | EXIT | |
| 13 | GLUE | Monte Rosa Therapeutics Inc | 股票-其他 | 2.24% | -0.57% | +48.08% | |
| 14 | VCYT | Veracyte Inc | 股票-其他 | 2.09% | +1.35% | +51.64% | |
| 15 | CGON | Cg Oncology Inc | 股票-其他 | 2.08% | -1.15% | EXIT | |
| 16 | RYTM | Rhythm Pharmaceuticals Inc | 股票-其他 | 2.02% | +0.87% | -63.26% | |
| 17 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 1.88% | +0.64% | +38.64% | |
| 18 | BIIB | Biogen Inc | 股票-醫療保健 | 1.84% | +0.13% | -6.23% | |
| 19 | INSM | Insmed Inc | 股票-醫療保健 | 1.72% | -0.22% | -65.52% | |
| 20 | 260 | Centessa Pharmaceuticals-adr | 股票-其他 | 1.59% | -1.89% | EXIT | |
| 21 | VRDN | Viridian Therapeutics Inc | 股票-其他 | 1.51% | — | +34.32% | |
| 22 | ASND | Ascendis Pharma A/S | 股票-其他 | 1.46% | -2.91% | EXIT | |
| 23 | PFE | Pfizer Inc | 股票-醫療保健 | 1.45% | — | — | |
| 24 | BNTC | Benitec Biopharma Inc | 股票-其他 | 1.37% | +0.17% | +164.86% | |
| 25 | AVTX | Avalo Therapeutics Inc | 股票-其他 | 1.32% | +0.96% | NEW | |
| 26 | GH | Guardant Health Inc | 股票-醫療保健 | 1.30% | +0.63% | — | |
| 27 | ORIC | Oric Pharmaceuticals Inc | 股票-其他 | 1.27% | -0.59% | -42.70% | |
| 28 | PCVX | Vaxcyte Inc | 股票-其他 | 0.95% | +0.02% | -52.67% | |
| 29 | TRVI | Trevi Therapeutics Inc | 股票-其他 | 0.94% | +0.69% | -8.08% | |
| 30 | GOSS | Gossamer Bio Inc | 股票-其他 | 0.92% | — | -55.31% | |
| 31 | SYRE | Spyre Therapeutics Inc | 股票-其他 | 0.85% | -0.41% | — | |
| 32 | LXEO | Lexeo Therapeutics Inc | 股票-其他 | 0.85% | — | -20.68% | |
| 33 | AMLX | Amylyx Pharmaceuticals Inc | 股票-其他 | 0.85% | — | -27.68% | |
| 34 | CERS | Cerus CORP | 股票-其他 | 0.81% | +0.46% | +3.63% | |
| 35 | CMPX | Compass Therapeutics Inc | 股票-其他 | 0.78% | -0.46% | EXIT | |
| 36 | SLNOEUR | Soleno Therapeutics Inc | 股票-其他 | 0.76% | — | — | |
| 37 | ✓ | Compugen LTD | 股票-其他 | 0.74% | -0.01% | +5.09% | |
| 38 | CLDX | Celldex Therapeutics Inc | 股票-其他 | 0.72% | -0.58% | EXIT | |
| 39 | OLMA | Olema Pharmaceuticals Inc | 股票-其他 | 0.72% | — | -77.90% | |
| 40 | ERAS | Erasca Inc | 股票-其他 | 0.68% | -0.66% | -3.69% | |
| 41 | ✓ | Kalvista Pharmaceuticals Inc | 股票-其他 | 0.65% | — | — | |
| 42 | FULC | Fulcrum Therapeutics Inc | 股票-其他 | 0.62% | -0.33% | EXIT | |
| 43 | ✓ | Fulcrum Therapeutics Inc | 股票-其他 | 0.62% | -0.16% | — | |
| 44 | AARD | Aardvark Therapeutics Inc | 股票-其他 | 0.55% | -0.01% | EXIT | |
| 45 | CCCC | C4 Therapeutics Inc | 股票-其他 | 0.53% | +0.96% | +5.10% | |
| 46 | SRZN | Surrozen Inc | 股票-其他 | 0.49% | -0.43% | EXIT | |
| 47 | CTNM | Contineum Therapeutics Inc-a | 股票-其他 | 0.49% | +0.10% | +85.09% | |
| 48 | MLYS | Mineralys Therapeutics Inc | 股票-其他 | 0.48% | — | +18.73% | |
| 49 | RLAY | Relay Therapeutics Inc | 股票-其他 | 0.47% | — | — | |
| 50 | ABEO | Abeona Therapeutics Inc | 股票-其他 | 0.46% | +0.09% | -36.90% |
| # | 代號 | 標的名稱 | 佔比變動 | 持倉量變化 | 異動類型 |
|---|---|---|---|---|---|
| 1 | CELC | Celcuity Inc | +4.6% | +322.99% | 加碼 |
| 2 | COGT | Cogent Biosciences Inc | +4.6% | +52.78% | 加碼 |
| 3 | 4XC1 | Kalvista Pharmaceuticals Inc | +3.2% | +78.02% | 加碼 |
| 4 | PRAX | Praxis Precision Medicines I | +3% | +61.03% | 加碼 |
| 5 | KOD | Kodiak Sciences Inc | +1.8% | +2.31% | 加碼 |
| 6 | ABVX | Abivax Sa-adr | +1.7% | -21.77% | 減碼 |
| 7 | GLUE | Monte Rosa Therapeutics Inc | +1.6% | +48.08% | 加碼 |
| 8 | URGN | UroGen Pharma Ltd. | +1.4% | +10.24% | 加碼 |
| 9 | 260 | Centessa Pharmaceuticals-adr | +1.1% | +224.42% | 加碼 |
| 10 | VCYT | Veracyte Inc | +1% | +51.64% | 加碼 |
| 11 | SNDX | Syndax Pharmaceuticals Inc | +0.9% | +38.64% | 加碼 |
| 12 | BNTC | Benitec Biopharma Inc | +0.9% | +164.86% | 加碼 |
| 13 | VRDN | Viridian Therapeutics Inc | +0.8% | +34.32% | 加碼 |
| 14 | GUTS | Fractyl Health Inc | +0.7% | -7.17% | 減碼 |
| 15 | DNTH | Dianthus Therapeutics Inc | +0.7% | +11.14% | 加碼 |
| 16 | BIIB | Biogen Inc | +0.3% | -6.23% | 減碼 |
| 17 | ERAS | Erasca Inc | +0.3% | -3.69% | 減碼 |
| 18 | CTNM | Contineum Therapeutics Inc-a | +0.2% | +85.09% | 加碼 |
| 19 | CERS | Cerus CORP | +0.2% | +3.63% | 加碼 |
| 20 | TRVI | Trevi Therapeutics Inc | +0.2% | -8.08% | 減碼 |
| 21 | LXEO | Lexeo Therapeutics Inc | +0.2% | -20.68% | 減碼 |
| 22 | ✓ | Compugen LTD | +0.1% | +5.09% | 加碼 |
| 23 | AVTX | Avalo Therapeutics Inc | +0.1% | -27.25% | 減碼 |
| 24 | MLYS | Mineralys Therapeutics Inc | +0.1% | +18.73% | 加碼 |
| 25 | ASND | Ascendis Pharma A/S | 0% | -8.08% | 減碼 |
| 26 | NUVL | Nuvalent Inc-a | 0% | -16.35% | 減碼 |
| 27 | AARD | Aardvark Therapeutics Inc | — | -0.97% | 減碼 |
| 28 | RADX | Radiopharm Theranostics LTD | — | — | 不變 |
| 29 | RCKTW | Rocket Pharmaceuticals In-27 | — | — | 不變 |
| 30 | CCCC | C4 Therapeutics Inc | 0% | +5.10% | 加碼 |
| 31 | ELUT | Elutia Inc | -0.1% | -3.50% | 減碼 |
| 32 | TELA | Tela Bio Inc | -0.1% | -4.87% | 減碼 |
| 33 | SION | Sionna Therapeutics Inc | -0.2% | -61.89% | 減碼 |
| 34 | ABEO | Abeona Therapeutics Inc | -0.3% | -36.90% | 減碼 |
| 35 | AMLX | Amylyx Pharmaceuticals Inc | -0.4% | -27.68% | 減碼 |
| 36 | CLDX | Celldex Therapeutics Inc | -0.5% | -45.24% | 減碼 |
| 37 | OLMA | Olema Pharmaceuticals Inc | -0.5% | -77.90% | 減碼 |
| 38 | CMPX | Compass Therapeutics Inc | -0.6% | -62.90% | 減碼 |
| 39 | PCVX | Vaxcyte Inc | -0.6% | -52.67% | 減碼 |
| 40 | GOSS | Gossamer Bio Inc | -0.8% | -55.31% | 減碼 |
| 41 | RAPP | Rapport Therapeutics Inc | -0.8% | -95.26% | 減碼 |
| 42 | CGON | Cg Oncology Inc | -1.4% | -43.42% | 減碼 |
| 43 | ✓ | Ultragenyx Pharmaceutical In | -1.8% | -79.17% | 減碼 |
| 44 | ORIC | Oric Pharmaceuticals Inc | -1.9% | -42.70% | 減碼 |
| 45 | INSM | Insmed Inc | -2.3% | -65.52% | 減碼 |
| 46 | RYTM | Rhythm Pharmaceuticals Inc | -3% | -63.26% | 減碼 |
| 47 | QURE | uniQure N.V. | -3.2% | -72.30% | 減碼 |
| 48 | RNAGBP | Avidity Biosciences Inc | — | EXIT | 清倉 |
| 49 | AKRO | Akero Therapeutics Inc | — | EXIT | 清倉 |
| 50 | ✓ | United Therapeutics CORP Del | — | EXIT | 清倉 |
根據 SEC 官方 Form 13F 申報備案，Silverarc Capital Management, LLC 在 Q4 2025 季度的美股持倉總市值約為 US$9.6億，共申報了 68 個公開持股部位。
在 Q4 2025 季度，Silverarc Capital Management, LLC 按市值排列的前三大核心持股分別為：ABVX (7.9%)、COGT (6.1%)、URGN (5.7%)。其中最大持股部位 ABVX 佔據整體投資組合約 7.9% 的權重。
精選 AlphaSMO 大戶持股與內部人交易深度分析，提升投資決策勝率
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
本季最大新建倉標的
IMNM
市值: US$2419.1萬
本季最大獲利了結 / 清倉標的
RNAGBP
前期市值: US$3680.1萬
在 Q4 2025 季度中，Silverarc Capital Management, LLC 共進行了 101 項持倉異動，包含新建倉 21 個部位、加碼 18 個部位、減碼 27 個部位以及清倉 35 個部位。 其中最大新建倉標的為 IMNM。 本季清倉部位包含 RNAGBP。
本頁面所有持股數據均直接同步自美國證券交易委員會（SEC）EDGAR 官方系統之 13F-HR / 13F-HR/A 季度申報文件。AlphaSMO 透過機器解析 CUSIP 與個股對照，提供 100% 精準對齊的歷史時序數據集，並支援 Schema.org 結構化資料格式。
解析公司高管、董事與 10% 大股東之 Form 4 內部人交易申報，掌握高管自家股票買賣第一手訊號。
深入剖析 5% 股益申報門檻、13D 與 13G 之差異，以及最新 SEC 申報時程規範，洞察機構法人的激進投資動向。