13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
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CIK: 0001802630
申报总市值
US$29.0亿
US$29.0亿
93 檔
27.9%
Q1 2026 季度申报显示，Soleus Capital Management, L.P. 披露的美股组合总市值为 US$29.0亿，涵盖 93 个不同之权益投资仓位。
Soleus Capital Management, L.P. 在 Q1 2026 进行了结构性的板块轮动与仓位换股。在开立 25 个全新仓位及加仓 29 档持股的同时，亦同步清仓 27 档并减仓 30 档标的。
在资产配置集中度方面，Soleus Capital Management, L.P. 的前 5 大核心持股（包含 KRYS, CELC, TGTX 等）合计占整体申报市值的 27.9%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | KRYS | Krystal Biotech Inc | 股票-医疗保健 | 12.06% | -0.03% | +22.53% | |
| 2 | CELC | Celcuity Inc | 股票-其他 | 5.94% | +0.20% | -28.97% | |
| 3 | TGTX | Tg Therapeutics Inc | 股票-医疗保健 | 5.42% | +0.12% | +28.35% | |
| 4 | PODD | Insulet CORP | 股票-医疗保健 | 4.78% | +0.72% | +275.00% | |
| 5 | NVCR | NovoCure Limited | 股票-医疗保健 | 4.63% | +0.55% | +23.00% | |
| 6 | UTHR | United Therapeutics CORP | 股票-医疗保健 | 4.50% | -0.29% | +211.98% | |
| 7 | PRAX | Praxis Precision Medicines I | 股票-其他 | 4.31% | -2.26% | -8.94% | |
| 8 | VCEL | Vericel CORP | 股票-其他 | 3.32% | -1.08% | +233.65% | |
| 9 | ALKS | Alkermes plc | 股票-医疗保健 | 2.82% | -0.96% | +49.04% | |
| 10 | ANIP | Ani Pharmaceuticals Inc | 股票-其他 | 2.55% | -0.07% | +68.69% | |
| 11 | GMED | Globus Medical Inc - A | 股票-医疗保健 | 2.55% | -1.27% | -17.76% | |
| 12 | GERN | Geron CORP | 股票-其他 | 2.50% | -0.61% | +78.23% | |
| 13 | TWST | Twist Bioscience CORP | 股票-其他 | 2.36% | -1.99% | -34.12% | |
| 14 | EWTX | Edgewise Therapeutics Inc | 股票-其他 | 1.85% | -1.22% | +59.33% | |
| 15 | BBNX | Beta Bionics Inc | 股票-其他 | 1.77% | +0.60% | +71.80% | |
| 16 | ALNY | Alnylam Pharmaceuticals Inc | 股票-医疗保健 | 1.76% | -1.42% | +88.07% | |
| 17 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 1.63% | -0.40% | -23.15% | |
| 18 | INDV | Indivior Pharmaceuticals Inc | 股票-其他 | 1.57% | -0.07% | — | |
| 19 | NPCE | Neuropace Inc | 股票-其他 | 1.56% | +0.03% | +8.47% | |
| 20 | LIVN | LivaNova PLC | 股票-其他 | 1.50% | -0.78% | +2.64% | |
| 21 | MIRM | Mirum Pharmaceuticals Inc | 股票-其他 | 1.50% | -1.20% | -30.21% | |
| 22 | BMRN | Biomarin Pharmaceutical Inc | 股票-医疗保健 | 1.49% | -0.75% | -50.71% | |
| 23 | PGNY | Progyny Inc | 股票-其他 | 1.42% | +0.17% | — | |
| 24 | INSP | Inspire Medical Systems Inc | 股票-医疗保健 | 1.20% | +1.77% | +92.49% | |
| 25 | FOCL | Edap Tms SA -adr | 股票-其他 | 1.10% | +0.20% | — | |
| 26 | KNSA | Kiniksa Pharmaceuticals International, plc | 股票-其他 | 1.02% | -0.48% | -11.18% | |
| 27 | MRK | Merck & Co. Inc. | 股票-医疗保健 | 0.99% | -0.77% | — | |
| 28 | ORGO | Organogenesis Holdings Inc | 股票-其他 | 0.97% | -0.12% | +1.00% | |
| 29 | NTRA | Natera Inc | 股票-医疗保健 | 0.96% | -0.95% | +495.00% | |
| 30 | AXGN | Axogen Inc | 股票-其他 | 0.91% | -0.82% | -43.72% | |
| 31 | PCVX | Vaxcyte Inc | 股票-其他 | 0.91% | -0.91% | EXIT | |
| 32 | ICLR | ICON Public Limited Company | 股票-医疗保健 | 0.86% | -0.86% | EXIT | |
| 33 | PHVS | Pharvaris N.V. | 股票-其他 | 0.80% | +0.07% | — | |
| 34 | CERS | Cerus CORP | 股票-其他 | 0.79% | -0.54% | +168.84% | |
| 35 | TRVI | Trevi Therapeutics Inc | 股票-其他 | 0.78% | -0.02% | +80.00% | |
| 36 | IKT | Inhibikase Therapeutics Inc | 股票-其他 | 0.74% | +0.02% | — | |
| 37 | CNTX | Context Therapeutics Inc | 股票-其他 | 0.74% | -0.61% | — | |
| 38 | VIR | Vir Biotechnology Inc | 股票-其他 | 0.73% | -0.38% | — | |
| 39 | XENE | Xenon Pharmaceuticals Inc | 股票-其他 | 0.69% | -0.13% | — | |
| 40 | TVTX | Travere Therapeutics Inc | 股票-其他 | 0.66% | -0.66% | EXIT | |
| 41 | TNDM | Tandem Diabetes Care Inc | 股票-其他 | 0.61% | -0.31% | — | |
| 42 | NRIX | Nurix Therapeutics Inc | 股票-其他 | 0.59% | +0.63% | -23.06% | |
| 43 | URGN | UroGen Pharma Ltd. | 股票-其他 | 0.53% | +0.52% | +384.67% | |
| 44 | SION | Sionna Therapeutics Inc | 股票-其他 | 0.48% | -0.21% | +9.31% | |
| 45 | CORT | Corcept Therapeutics Inc | 股票-医疗保健 | 0.47% | -0.41% | — | |
| 46 | JBIO | Jade Biosciences Inc | 股票-其他 | 0.45% | +0.74% | — | |
| 47 | VCYT | Veracyte Inc | 股票-其他 | 0.42% | -0.37% | +3099.12% | |
| 48 | IVVD | Invivyd Inc | 股票-其他 | 0.41% | -0.18% | — | |
| 49 | CCCC | C4 Therapeutics Inc | 股票-其他 | 0.41% | +0.13% | — | |
| 50 | KIDS | Orthopediatrics CORP | 股票-其他 | 0.40% | +0.08% | +17.13% |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | KRYS | Krystal Biotech Inc | +3.5% | +22.53% | 加仓 |
| 2 | UTHR | United Therapeutics CORP | +3.4% | +211.98% | 加仓 |
| 3 | PODD | Insulet CORP | +3.2% | +275.00% | 加仓 |
| 4 | VCEL | Vericel CORP | +2.3% | +233.65% | 加仓 |
| 5 | TGTX | Tg Therapeutics Inc | +2% | +28.35% | 加仓 |
| 6 | ALKS | Alkermes plc | +1.5% | +49.04% | 加仓 |
| 7 | GERN | Geron CORP | +1.4% | +78.23% | 加仓 |
| 8 | ANIP | Ani Pharmaceuticals Inc | +1.1% | +68.69% | 加仓 |
| 9 | EWTX | Edgewise Therapeutics Inc | +1% | +59.33% | 加仓 |
| 10 | NTRA | Natera Inc | +0.8% | +495.00% | 加仓 |
| 11 | ALNY | Alnylam Pharmaceuticals Inc | +0.7% | +88.07% | 加仓 |
| 12 | NVCR | NovoCure Limited | +0.6% | +23.00% | 加仓 |
| 13 | CERS | Cerus CORP | +0.5% | +168.84% | 加仓 |
| 14 | VCYT | Veracyte Inc | +0.4% | +3099.12% | 加仓 |
| 15 | URGN | UroGen Pharma Ltd. | +0.4% | +384.67% | 加仓 |
| 16 | TNGX | Tango Therapeutics Inc | +0.4% | +4400.00% | 加仓 |
| 17 | TRVI | Trevi Therapeutics Inc | +0.4% | +80.00% | 加仓 |
| 18 | PRAX | Praxis Precision Medicines I | +0.4% | -8.94% | 减仓 |
| 19 | INBX | Inhibrx Biosciences Inc | +0.3% | +424.00% | 加仓 |
| 20 | FOCL | Edap Tms SA -adr | +0.2% | — | 不变 |
| 21 | LIVN | LivaNova PLC | +0.2% | +2.64% | 加仓 |
| 22 | INSP | Inspire Medical Systems Inc | +0.2% | +92.49% | 加仓 |
| 23 | TWST | Twist Bioscience CORP | +0.2% | -34.12% | 减仓 |
| 24 | CCCC | C4 Therapeutics Inc | +0.1% | — | 不变 |
| 25 | KNSA | Kiniksa Pharmaceuticals International, plc | +0.1% | -11.18% | 减仓 |
| 26 | EOLS | Evolus Inc | +0.1% | +109.85% | 加仓 |
| 27 | PHVS | Pharvaris N.V. | +0.1% | — | 不变 |
| 28 | SION | Sionna Therapeutics Inc | +0.1% | +9.31% | 加仓 |
| 29 | KIDS | Orthopediatrics CORP | +0.1% | +17.13% | 加仓 |
| 30 | NPCE | Neuropace Inc | 0% | +8.47% | 加仓 |
| 31 | QNRX | Quoin Pharmaceuticals Lt-adr | 0% | +190.92% | 加仓 |
| 32 | JBIO | Jade Biosciences Inc | — | — | 不变 |
| 33 | STAA | Staar Surgical Co | — | -20.00% | 减仓 |
| 34 | JSPR | Jasper Therapeutics Inc | — | +38.16% | 加仓 |
| 35 | LBRX | Lb Pharmaceuticals Inc | — | — | 不变 |
| 36 | NSPR | Inspiremd Inc | 0% | -9.07% | 减仓 |
| 37 | LUNG | Pulmonx CORP | 0% | +36.80% | 加仓 |
| 38 | KPTI | Karyopharm Therapeutics Inc | 0% | — | 不变 |
| 39 | AVTX | Avalo Therapeutics Inc | 0% | — | 不变 |
| 40 | GPCR | Structure Therapeutics Inc | -0.1% | -11.11% | 减仓 |
| 41 | IKT | Inhibikase Therapeutics Inc | -0.1% | — | 不变 |
| 42 | ZYME | Zymeworks Inc | -0.1% | -90.00% | 减仓 |
| 43 | TYRA | Tyra Biosciences Inc | -0.1% | -92.00% | 减仓 |
| 44 | SNDX | Syndax Pharmaceuticals Inc | -0.1% | -23.15% | 减仓 |
| 45 | SEPN | Septerna Inc | -0.1% | -28.27% | 减仓 |
| 46 | PCVX | Vaxcyte Inc | -0.1% | -36.70% | 减仓 |
| 47 | COGT | Cogent Biosciences Inc | -0.1% | -91.67% | 减仓 |
| 48 | NEO | Neogenomics Inc | -0.1% | -59.06% | 减仓 |
| 49 | MIRM | Mirum Pharmaceuticals Inc | -0.2% | -30.21% | 减仓 |
| 50 | ORKA | Oruka Therapeutics Inc | -0.2% | -97.37% | 减仓 |
根据 SEC 官方 Form 13F 申报备案，Soleus Capital Management, L.P. 在 Q1 2026 季度的美股持仓总市值约为 US$29.0亿，共申报了 93 个公开持股仓位。
在 Q1 2026 季度，Soleus Capital Management, L.P. 按市值排列的前三大核心持股分别为：KRYS (12.1%)、CELC (5.9%)、TGTX (5.4%)。其中最大持股仓位 KRYS 占据整体投资组合约 12.1% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
INDV
市值: US$3883.2万
本季最大获利了结 / 清仓标的
XBI
前期市值: US$3.5亿
在 Q1 2026 季度中，Soleus Capital Management, L.P. 共进行了 111 项持仓异动，包含新建仓 25 个仓位、加仓 29 个仓位、减仓 30 个仓位以及清仓 27 个仓位。 其中最大新建仓标的为 INDV。 本季清仓仓位包含 XBI。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
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深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。