13F 申報指南13F 觀念全攻略
什麼是 SEC Form 13F 申報？美股機構大戶持股全攻略
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
AlphaSMO 權威研究指南閱讀專題
CIK: 0001055951
申報總市值
US$53.7億
US$53.7億
112 檔
24.5%
Q1 2024 季度申報顯示，Orbimed Advisors LLC 揭露的美股組合總市值為 US$53.7億，涵蓋 112 個不同之權益投資部位。
Q1 2024 的申報記錄反映 Orbimed Advisors LLC 的板塊替換策略：機構本季推動了 21 筆增持與 24 筆減持，籌碼呈現明顯的結構重組。
檢視投資組合結構，前 5 大主力部位（包含 SVA, LLY, EWTX）占據了總市值的 24.5%，展現出該機構在 Q1 2024 的重點資金聚焦與風險分佈特徵。
| # | 代號 | 標的名稱 | 資產子類別 | 佔比 | 佔比變動 | 持倉量變化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SVA | Sinovac Biotech Ltd. | 股票-其他 | 6.23% | +3.06% | — | |
| 2 | LLY | Eli Lilly & Co | 股票-醫療保健 | 5.14% | +1.30% | -1.26% | |
| 3 | EWTX | Edgewise Therapeutics Inc | 股票-其他 | 5.02% | +1.73% | +3.12% | |
| 4 | BSX | Boston Scientific CORP | 股票-醫療保健 | 4.11% | -1.88% | -1.02% | |
| 5 | ISRG | Intuitive Surgical Inc | 股票-醫療保健 | 3.60% | -0.80% | -1.18% | |
| 6 | BIIB | Biogen Inc | 股票-醫療保健 | 3.56% | +0.02% | +8.86% | |
| 7 | MRK | Merck & Co. Inc. | 股票-醫療保健 | 3.18% | -0.05% | +24.74% | |
| 8 | JANX | Janux Therapeutics Inc | 股票-其他 | 2.95% | -0.13% | +28.86% | |
| 9 | ELVN | Enliven Therapeutics Inc | 股票-其他 | 2.90% | +0.02% | — | |
| 10 | THC | Tenet Healthcare CORP | 股票-醫療保健 | 2.26% | — | -4.17% | |
| 11 | BMRN | Biomarin Pharmaceutical Inc | 股票-醫療保健 | 2.05% | — | -18.64% | |
| 12 | NVLSEUR | Alpine Immune Sciences Inc | 股票-其他 | 1.95% | — | +5.73% | |
| 13 | IRON | Disc Medicine Inc | 股票-其他 | 1.94% | -0.91% | — | |
| 14 | SYK | Stryker CORP | 股票-醫療保健 | 1.76% | -0.30% | — | |
| 15 | SPRY | Ars Pharmaceuticals Inc | 股票-其他 | 1.73% | -0.12% | — | |
| 16 | SRPT | Sarepta Therapeutics Inc | 股票-醫療保健 | 1.65% | — | — | |
| 17 | IONS | Ionis Pharmaceuticals Inc | 股票-醫療保健 | 1.60% | — | -2.51% | |
| 18 | ELV | Elevance Health Inc | 股票-醫療保健 | 1.60% | +0.21% | +18.80% | |
| 19 | XTNT | Xtant Medical Holdings Inc | 股票-其他 | 1.57% | — | — | |
| 20 | EVH | Evolent Health Inc - A | 股票-其他 | 1.56% | — | -5.13% | |
| 21 | APLSUSD | Apellis Pharmaceuticals Inc | 股票-其他 | 1.56% | — | +56.99% | |
| 22 | SWTXUSD | Springworks Therapeutics Inc | 股票-其他 | 1.54% | — | -46.97% | |
| 23 | KROS | Keros Therapeutics Inc | 股票-其他 | 1.54% | -0.02% | — | |
| 24 | NTRA | Natera Inc | 股票-醫療保健 | 1.51% | +0.26% | -5.77% | |
| 25 | TMO | Thermo Fisher Scientific Inc | 股票-醫療保健 | 1.41% | +0.38% | -8.21% | |
| 26 | PCVX | Vaxcyte Inc | 股票-其他 | 1.33% | — | -7.54% | |
| 27 | CRNX | Crinetics Pharmaceuticals In | 股票-其他 | 1.19% | -0.04% | -16.93% | |
| 28 | SRRK | Scholar Rock Holding CORP | 股票-其他 | 1.16% | — | -15.79% | |
| 29 | ARGX | Argenx Se - Adr | 股票-醫療保健 | 1.09% | -0.44% | +79.20% | |
| 30 | ICLR | ICON Public Limited Company | 股票-醫療保健 | 1.07% | — | +31.69% | |
| 31 | NBIX | Neurocrine Biosciences Inc | 股票-醫療保健 | 1.07% | — | -18.52% | |
| 32 | SIBN | Si-bone Inc | 股票-其他 | 1.03% | — | +49.38% | |
| 33 | VRNA | Verona Pharma PLC - Adr | 股票-其他 | 1.00% | — | -10.05% | |
| 34 | ✓ | Third Harmonic Bio Inc | 股票-其他 | 1.00% | — | — | |
| 35 | AVBP | Arrivent Biopharma Inc | 股票-其他 | 0.99% | +0.53% | — | |
| 36 | NPCE | Neuropace Inc | 股票-其他 | 0.97% | -0.11% | — | |
| 37 | PRLD | Prelude Therapeutics Inc | 股票-其他 | 0.95% | +0.60% | — | |
| 38 | VRTX | Vertex Pharmaceuticals Inc | 股票-醫療保健 | 0.94% | — | -29.97% | |
| 39 | 430 | Terns Pharmaceuticals Inc | 股票-其他 | 0.92% | — | — | |
| 40 | CYTK | Cytokinetics Inc | 股票-醫療保健 | 0.88% | +0.04% | NEW | |
| 41 | APGE | Apogee Therapeutics Inc | 股票-其他 | 0.87% | — | -43.74% | |
| 42 | CMPX | Compass Therapeutics Inc | 股票-其他 | 0.81% | -1.03% | — | |
| 43 | GERN | Geron CORP | 股票-其他 | 0.78% | — | +2558.48% | |
| 44 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 0.76% | +0.17% | — | |
| 45 | QTTB | Q32 Bio Inc | 股票-其他 | 0.70% | +0.68% | — | |
| 46 | ESPR | Esperion Therapeutics Inc | 股票-其他 | 0.67% | -0.59% | EXIT | |
| 47 | ✓ | Ikena Oncology Inc | 股票-其他 | 0.66% | -0.45% | EXIT | |
| 48 | UNH | Unitedhealth Group Inc | 股票-醫療保健 | 0.63% | +1.33% | NEW | |
| 49 | RYTM | Rhythm Pharmaceuticals Inc | 股票-其他 | 0.56% | +0.11% | +31.34% | |
| 50 | ALXO | Alx Oncology Holdings Inc | 股票-其他 | 0.56% | -0.01% | -12.18% |
| # | 代號 | 標的名稱 | 佔比變動 | 持倉量變化 | 異動類型 |
|---|---|---|---|---|---|
| 1 | JANX | Janux Therapeutics Inc | +2.2% | +28.86% | 加碼 |
| 2 | EWTX | Edgewise Therapeutics Inc | +1.8% | +3.12% | 加碼 |
| 3 | NVLSEUR | Alpine Immune Sciences Inc | +1% | +5.73% | 加碼 |
| 4 | AVBP | Arrivent Biopharma Inc | +1% | NEW | 新建倉 |
| 5 | LLY | Eli Lilly & Co | +0.9% | -1.26% | 減碼 |
| 6 | MRK | Merck & Co. Inc. | +0.9% | +24.74% | 加碼 |
| 7 | CYTK | Cytokinetics Inc | +0.9% | NEW | 新建倉 |
| 8 | GERN | Geron CORP | +0.8% | +2558.48% | 加碼 |
| 9 | SPRY | Ars Pharmaceuticals Inc | +0.7% | — | 不變 |
| 10 | QTTB | Q32 Bio Inc | +0.7% | NEW | 新建倉 |
| 11 | ESPR | Esperion Therapeutics Inc | +0.7% | NEW | 新建倉 |
| 12 | KROS | Keros Therapeutics Inc | +0.5% | — | 不變 |
| 13 | PRAX | Praxis Precision Medicines I | +0.5% | NEW | 新建倉 |
| 14 | MLYS | Mineralys Therapeutics Inc | +0.5% | NEW | 新建倉 |
| 15 | APLSUSD | Apellis Pharmaceuticals Inc | +0.5% | +56.99% | 加碼 |
| 16 | RNAGBP | Avidity Biosciences Inc | +0.5% | NEW | 新建倉 |
| 17 | ARGX | Argenx Se - Adr | +0.5% | +79.20% | 加碼 |
| 18 | ELVN | Enliven Therapeutics Inc | +0.4% | — | 不變 |
| 19 | THC | Tenet Healthcare CORP | +0.4% | -4.17% | 減碼 |
| 20 | DYN | Dyne Therapeutics Inc | +0.4% | NEW | 新建倉 |
| 21 | NTRA | Natera Inc | +0.3% | -5.77% | 減碼 |
| 22 | ICLR | ICON Public Limited Company | +0.3% | +31.69% | 加碼 |
| 23 | SRPT | Sarepta Therapeutics Inc | +0.3% | — | 不變 |
| 24 | HRTX | Heron Therapeutics Inc | +0.3% | +70.56% | 加碼 |
| 25 | BSX | Boston Scientific CORP | +0.3% | -1.02% | 減碼 |
| 26 | ELV | Elevance Health Inc | +0.3% | +18.80% | 加碼 |
| 27 | ISRG | Intuitive Surgical Inc | +0.2% | -1.18% | 減碼 |
| 28 | TYRA | Tyra Biosciences Inc | +0.2% | NEW | 新建倉 |
| 29 | MORFUSD | Morphic Holding Inc | +0.2% | +104.28% | 加碼 |
| 30 | APGE | Apogee Therapeutics Inc | +0.2% | -43.74% | 減碼 |
| 31 | SYK | Stryker CORP | +0.2% | — | 不變 |
| 32 | PFE | Pfizer Inc | -0.3% | EXIT | 清倉 |
| 33 | ALNY | Alnylam Pharmaceuticals Inc | -0.3% | EXIT | 清倉 |
| 34 | ALXO | Alx Oncology Holdings Inc | -0.4% | -12.18% | 減碼 |
| 35 | AMGN | Amgen Inc | -0.4% | -50.20% | 減碼 |
| 36 | SRRK | Scholar Rock Holding CORP | -0.4% | -15.79% | 減碼 |
| 37 | VRTX | Vertex Pharmaceuticals Inc | -0.5% | -29.97% | 減碼 |
| 38 | IONS | Ionis Pharmaceuticals Inc | -0.5% | -2.51% | 減碼 |
| 39 | VRNA | Verona Pharma PLC - Adr | -0.5% | -10.05% | 減碼 |
| 40 | ✓ | Fusion Pharmaceuticals Inc | -0.6% | EXIT | 清倉 |
| 41 | BIIB | Biogen Inc | -0.7% | +8.86% | 加碼 |
| 42 | IOVA | Iovance Biotherapeutics Inc | -0.8% | EXIT | 清倉 |
| 43 | SWTXUSD | Springworks Therapeutics Inc | -0.8% | -46.97% | 減碼 |
| 44 | BMRN | Biomarin Pharmaceutical Inc | -1% | -18.64% | 減碼 |
| 45 | HUM | Humana Inc | -1% | EXIT | 清倉 |
| 46 | RCM1USD | R1 Rcm Inc | -1% | EXIT | 清倉 |
| 47 | ✓ | Theseus Pharmaceuticals Inc | -1.4% | EXIT | 清倉 |
| 48 | UTHR | United Therapeutics CORP | -1.7% | EXIT | 清倉 |
| 49 | ✓ | Gracell Biotechnologies-adr | -1.9% | EXIT | 清倉 |
| 50 | ✓ | Rayzebio Inc | -2.9% | EXIT | 清倉 |
根據 SEC 官方 Form 13F 申報備案，Orbimed Advisors LLC 在 Q1 2024 季度的美股持倉總市值約為 US$53.7億，共申報了 112 個公開持股部位。
在 Q1 2024 季度，Orbimed Advisors LLC 按市值排列的前三大核心持股分別為：SVA (6.2%)、LLY (5.1%)、EWTX (5.0%)。其中最大持股部位 SVA 佔據整體投資組合約 6.2% 的權重。
精選 AlphaSMO 大戶持股與內部人交易深度分析，提升投資決策勝率
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
本季最大新建倉標的
AVBP
市值: US$5406.8萬
本季最大獲利了結 / 清倉標的
RAYZEBIO INC
前期市值: US$1.5億
在 Q1 2024 季度中，Orbimed Advisors LLC 共進行了 45 項持倉異動，包含新建倉 9 個部位、加碼 12 個部位、減碼 14 個部位以及清倉 10 個部位。 其中最大新建倉標的為 AVBP。 本季清倉部位包含 RAYZEBIO INC。
本頁面所有持股數據均直接同步自美國證券交易委員會（SEC）EDGAR 官方系統之 13F-HR / 13F-HR/A 季度申報文件。AlphaSMO 透過機器解析 CUSIP 與個股對照，提供 100% 精準對齊的歷史時序數據集，並支援 Schema.org 結構化資料格式。
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深入剖析 5% 股益申報門檻、13D 與 13G 之差異，以及最新 SEC 申報時程規範，洞察機構法人的激進投資動向。