13F 申報指南13F 觀念全攻略
什麼是 SEC Form 13F 申報？美股機構大戶持股全攻略
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
AlphaSMO 權威研究指南閱讀專題
CIK: 0001791827
申報總市值
US$6.2億
US$6.2億
62 檔
35.7%
在 Q4 2024 的 13F 官方備案中，Avidity Partners Management LP 管理的美股投資組合規模來到 US$6.2億，整體持股檔數為 62 檔。
從 Q4 2024 申報觀察，Avidity Partners Management LP 採取防禦導向的調倉策略，本季減碼 46 檔個股並出清 25 檔部位，顯示機構在該時期進行風險控制與流動性回收。
從部位權重觀察，前 5 大標的（包含 DNTH, BSX, JANX）累計市值佔比達 35.7%，是驅動 Avidity Partners Management LP 該季度整體投資組合績效表現的核心支柱。
| # | 代號 | 標的名稱 | 資產子類別 | 佔比 | 佔比變動 | 持倉量變化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | DNTH | Dianthus Therapeutics Inc | 股票-其他 | 6.15% | -2.91% | -1.52% | |
| 2 | BSX | Boston Scientific CORP | 股票-醫療保健 | 4.52% | -0.21% | -46.47% | |
| 3 | JANX | Janux Therapeutics Inc | 股票-其他 | 3.90% | — | +32.01% | |
| 4 | ARVN | Arvinas Inc | 股票-其他 | 3.87% | — | +37.47% | |
| 5 | NTRA | Natera Inc | 股票-醫療保健 | 3.48% | -0.36% | EXIT | |
| 6 | EXK | Exact Sciences CORP | 股票-原物料 | 3.33% | — | +2.55% | |
| 7 | ISRG | Intuitive Surgical Inc | 股票-醫療保健 | 3.32% | — | -56.28% | |
| 8 | CGON | Cg Oncology Inc | 股票-其他 | 3.09% | -1.75% | -33.71% | |
| 9 | UNH | Unitedhealth Group Inc | 股票-醫療保健 | 2.98% | -0.21% | EXIT | |
| 10 | NBIX | Neurocrine Biosciences Inc | 股票-醫療保健 | 2.95% | — | -52.09% | |
| 11 | IDYA | Ideaya Biosciences Inc | 股票-其他 | 2.84% | — | -17.94% | |
| 12 | JAZZ | Jazz Pharmaceuticals plc | 股票-醫療保健 | 2.84% | — | -45.59% | |
| 13 | MIRM | Mirum Pharmaceuticals Inc | 股票-其他 | 2.71% | — | -8.88% | |
| 14 | ACHC | Acadia Healthcare Co Inc | 股票-其他 | 2.56% | — | -33.20% | |
| 15 | GKOS | Glaukos CORP | 股票-醫療保健 | 2.50% | — | -50.71% | |
| 16 | DXCM | Dexcom Inc | 股票-醫療保健 | 2.43% | -0.06% | +32.50% | |
| 17 | TMO | Thermo Fisher Scientific Inc | 股票-醫療保健 | 2.28% | — | -34.99% | |
| 18 | HUM | Humana Inc | 股票-醫療保健 | 2.22% | — | -31.23% | |
| 19 | KYMR | Kymera Therapeutics Inc | 股票-其他 | 1.98% | — | — | |
| 20 | AVTR | Avantor Inc | 股票-醫療保健 | 1.96% | — | -23.32% | |
| 21 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 1.95% | — | -38.90% | |
| 22 | 260 | Centessa Pharmaceuticals-adr | 股票-其他 | 1.92% | — | -45.32% | |
| 23 | RVMD | Revolution Medicines Inc | 股票-醫療保健 | 1.92% | -0.30% | EXIT | |
| 24 | XENE | Xenon Pharmaceuticals Inc | 股票-其他 | 1.82% | — | -42.05% | |
| 25 | THC | Tenet Healthcare CORP | 股票-醫療保健 | 1.70% | — | -45.85% | |
| 26 | INSM | Insmed Inc | 股票-醫療保健 | 1.58% | — | -60.68% | |
| 27 | AXSM | Axsome Therapeutics Inc | 股票-醫療保健 | 1.56% | — | -36.51% | |
| 28 | 2655787D | Blueprint Medicines CORP | 股票-其他 | 1.51% | — | -43.94% | |
| 29 | DHR | Danaher CORP | 股票-醫療保健 | 1.51% | — | -29.47% | |
| 30 | RARE | Ultragenyx Pharmaceutical In | 股票-其他 | 1.45% | — | -53.19% | |
| 31 | ILMN | Illumina Inc | 股票-醫療保健 | 1.44% | — | -62.43% | |
| 32 | ABBV | Abbvie Inc | 股票-醫療保健 | 1.41% | — | -19.30% | |
| 33 | RCKT | Rocket Pharmaceuticals Inc | 股票-其他 | 1.30% | — | +40.63% | |
| 34 | BMY | Bristol-myers Squibb Co | 股票-醫療保健 | 1.19% | — | -18.25% | |
| 35 | TMDX | Transmedics Group Inc | 股票-醫療保健 | 1.18% | — | +597.10% | |
| 36 | PHAT | Phathom Pharmaceuticals Inc | 股票-其他 | 1.11% | -0.21% | -22.96% | |
| 37 | SGRY | Surgery Partners Inc | 股票-其他 | 1.07% | — | -37.82% | |
| 38 | ORIC | Oric Pharmaceuticals Inc | 股票-其他 | 1.00% | — | -12.57% | |
| 39 | NAMS | NewAmsterdam Pharma Company N.V. | 股票-其他 | 0.89% | — | -60.21% | |
| 40 | INCY | Incyte CORP | 股票-醫療保健 | 0.88% | — | -57.94% | |
| 41 | CATX | Perspective Therapeutics Inc | 股票-其他 | 0.84% | -1.67% | -21.76% | |
| 42 | ASND | Ascendis Pharma A/S | 股票-其他 | 0.84% | — | -47.90% | |
| 43 | BHVN | Biohaven Ltd. | 股票-其他 | 0.82% | — | -52.06% | |
| 44 | ITCIEUR | Intra-cellular Therapies Inc | 股票-其他 | 0.80% | — | -58.37% | |
| 45 | VTLUSD | Immunic Inc | 股票-其他 | 0.78% | -1.51% | EXIT | |
| 46 | CNTX | Context Therapeutics Inc | 股票-其他 | 0.77% | -2.21% | +0.81% | |
| 47 | ORKA | Oruka Therapeutics Inc | 股票-其他 | 0.67% | +4.04% | -55.48% | |
| 48 | REGN | Regeneron Pharmaceuticals | 股票-醫療保健 | 0.59% | — | — | |
| 49 | BRKR | Bruker CORP | 股票-醫療保健 | 0.44% | — | — | |
| 50 | VERA | Vera Therapeutics Inc | 股票-其他 | 0.42% | — | — |
| # | 代號 | 標的名稱 | 佔比變動 | 持倉量變化 | 異動類型 |
|---|---|---|---|---|---|
| 1 | JANX | Janux Therapeutics Inc | +2.6% | +32.01% | 加碼 |
| 2 | DNTH | Dianthus Therapeutics Inc | +2.1% | -1.52% | 減碼 |
| 3 | ARVN | Arvinas Inc | +2% | +37.47% | 加碼 |
| 4 | DXCM | Dexcom Inc | +1.6% | +32.50% | 加碼 |
| 5 | EXK | Exact Sciences CORP | +1.3% | +2.55% | 加碼 |
| 6 | MIRM | Mirum Pharmaceuticals Inc | +1.3% | -8.88% | 減碼 |
| 7 | TMDX | Transmedics Group Inc | +1% | +597.10% | 加碼 |
| 8 | KYMR | Kymera Therapeutics Inc | +0.8% | — | 不變 |
| 9 | IDYA | Ideaya Biosciences Inc | +0.6% | -17.94% | 減碼 |
| 10 | REGN | Regeneron Pharmaceuticals | +0.6% | NEW | 新建倉 |
| 11 | RCKT | Rocket Pharmaceuticals Inc | +0.6% | +40.63% | 加碼 |
| 12 | BMY | Bristol-myers Squibb Co | +0.5% | -18.25% | 減碼 |
| 13 | BRKR | Bruker CORP | +0.4% | NEW | 新建倉 |
| 14 | VERA | Vera Therapeutics Inc | +0.4% | NEW | 新建倉 |
| 15 | BSX | Boston Scientific CORP | +0.4% | -46.47% | 減碼 |
| 16 | ABBV | Abbvie Inc | +0.4% | -19.30% | 減碼 |
| 17 | JAZZ | Jazz Pharmaceuticals plc | +0.4% | -45.59% | 減碼 |
| 18 | UNH | Unitedhealth Group Inc | +0.4% | -31.35% | 減碼 |
| 19 | AVTR | Avantor Inc | +0.3% | -23.32% | 減碼 |
| 20 | 2KZ0 | Kezar Life Sciences Inc | +0.3% | NEW | 新建倉 |
| 21 | NBIX | Neurocrine Biosciences Inc | +0.3% | -52.09% | 減碼 |
| 22 | ORIC | Oric Pharmaceuticals Inc | +0.2% | -12.57% | 減碼 |
| 23 | AKRO | Akero Therapeutics Inc | +0.2% | NEW | 新建倉 |
| 24 | QURE | uniQure N.V. | +0.2% | -67.04% | 減碼 |
| 25 | GKOS | Glaukos CORP | +0.2% | -50.71% | 減碼 |
| 26 | AXSM | Axsome Therapeutics Inc | +0.2% | -36.51% | 減碼 |
| 27 | 260 | Centessa Pharmaceuticals-adr | +0.2% | -45.32% | 減碼 |
| 28 | XENE | Xenon Pharmaceuticals Inc | +0.2% | -42.05% | 減碼 |
| 29 | DHR | Danaher CORP | +0.2% | -29.47% | 減碼 |
| 30 | NAMS | NewAmsterdam Pharma Company N.V. | +0.1% | -60.21% | 減碼 |
| 31 | TMO | Thermo Fisher Scientific Inc | +0.1% | -34.99% | 減碼 |
| 32 | HUM | Humana Inc | +0.1% | -31.23% | 減碼 |
| 33 | RVMD | Revolution Medicines Inc | +0.1% | -43.52% | 減碼 |
| 34 | VTLUSD | Immunic Inc | +0.1% | -3.62% | 減碼 |
| 35 | BLE0 | Bluebird Bio Inc | +0.1% | NEW | 新建倉 |
| 36 | SCYXEUR | Scynexis Inc | 0% | -15.17% | 減碼 |
| 37 | KPTIEUR | Karyopharm Therapeutics Inc | 0% | — | 不變 |
| 38 | CNTX | Context Therapeutics Inc | 0% | +0.81% | 加碼 |
| 39 | HYPR | Hyperfine Inc | 0% | — | 不變 |
| 40 | 2655787D | Blueprint Medicines CORP | 0% | -43.94% | 減碼 |
| 41 | ✓ | Caremax Inc | — | EXIT | 清倉 |
| 42 | ✓ | 0% | EXIT | 清倉 | |
| 43 | ASND | Ascendis Pharma A/S | -0.1% | -47.90% | 減碼 |
| 44 | ITCIEUR | Intra-cellular Therapies Inc | -0.1% | -58.37% | 減碼 |
| 45 | DYN | Dyne Therapeutics Inc | -0.1% | -41.82% | 減碼 |
| 46 | PRLD | Prelude Therapeutics Inc | -0.1% | EXIT | 清倉 |
| 47 | CGON | Cg Oncology Inc | -0.1% | -33.71% | 減碼 |
| 48 | TIL | Instil Bio Inc | -0.1% | EXIT | 清倉 |
| 49 | NTRA | Natera Inc | -0.1% | -59.78% | 減碼 |
| 50 | SYRS | Syros Pharmaceuticals Inc | -0.1% | EXIT | 清倉 |
根據 SEC 官方 Form 13F 申報備案，Avidity Partners Management LP 在 Q4 2024 季度的美股持倉總市值約為 US$6.2億，共申報了 62 個公開持股部位。
在 Q4 2024 季度，Avidity Partners Management LP 按市值排列的前三大核心持股分別為：DNTH (6.2%)、BSX (4.5%)、JANX (3.9%)。其中最大持股部位 DNTH 佔據整體投資組合約 6.2% 的權重。
精選 AlphaSMO 大戶持股與內部人交易深度分析，提升投資決策勝率
完整解讀 Form 13F 申報規範、1 億美元門檻與 45 天延遲申報機制，學會如何追蹤頂級對沖基金與機構法人持倉動向。
本季最大新建倉標的
REGN
市值: US$598.4萬
本季最大獲利了結 / 清倉標的
BMRN
前期市值: US$2249.3萬
在 Q4 2024 季度中，Avidity Partners Management LP 共進行了 84 項持倉異動，包含新建倉 6 個部位、加碼 7 個部位、減碼 46 個部位以及清倉 25 個部位。 其中最大新建倉標的為 REGN。 本季清倉部位包含 BMRN。
本頁面所有持股數據均直接同步自美國證券交易委員會（SEC）EDGAR 官方系統之 13F-HR / 13F-HR/A 季度申報文件。AlphaSMO 透過機器解析 CUSIP 與個股對照，提供 100% 精準對齊的歷史時序數據集，並支援 Schema.org 結構化資料格式。
解析公司高管、董事與 10% 大股東之 Form 4 內部人交易申報，掌握高管自家股票買賣第一手訊號。
深入剖析 5% 股益申報門檻、13D 與 13G 之差異，以及最新 SEC 申報時程規範，洞察機構法人的激進投資動向。