13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
AlphaSMO 权威研究指南阅读专题
CIK: 0001055951
申报总市值
US$53.7亿
US$53.7亿
110 檔
25.9%
根据最新整理的 13F 季度数据集，Orbimed Advisors LLC 于 Q2 2024 结束时的管理资产规模为 US$53.7亿。该机构在本季度申报了 110 档美股持仓，呈现出该时期的主要投资地图。
Orbimed Advisors LLC 在 Q2 2024 进行了结构性的板块轮动与仓位换股。在开立 5 个全新仓位及加仓 11 档持股的同时，亦同步清仓 7 档并减仓 12 档标的。
在资产配置集中度方面，Orbimed Advisors LLC 的前 5 大核心持股（包含 SVA, LLY, EWTX 等）合计占整体申报市值的 25.9%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SVA | Sinovac Biotech Ltd. | 股票-其他 | 6.71% | +3.06% | — | |
| 2 | LLY | Eli Lilly & Co | 股票-医疗保健 | 6.04% | +1.30% | -6.43% | |
| 3 | EWTX | Edgewise Therapeutics Inc | 股票-其他 | 5.34% | +1.73% | — | |
| 4 | BSX | Boston Scientific CORP | 股票-医疗保健 | 4.98% | -1.88% | — | |
| 5 | ISRG | Intuitive Surgical Inc | 股票-医疗保健 | 4.33% | -0.80% | — | |
| 6 | BIIB | Biogen Inc | 股票-医疗保健 | 4.12% | +0.02% | — | |
| 7 | ELVN | Enliven Therapeutics Inc | 股票-其他 | 3.67% | +0.02% | -11.54% | |
| 8 | MRK | Merck & Co. Inc. | 股票-医疗保健 | 3.22% | -0.05% | — | |
| 9 | THC | Tenet Healthcare CORP | 股票-医疗保健 | 3.08% | — | — | |
| 10 | JANX | Janux Therapeutics Inc | 股票-其他 | 2.46% | -0.13% | -30.31% | |
| 11 | IONS | Ionis Pharmaceuticals Inc | 股票-医疗保健 | 2.23% | — | +17.85% | |
| 12 | SRPT | Sarepta Therapeutics Inc | 股票-医疗保健 | 2.17% | — | -0.22% | |
| 13 | SYK | Stryker CORP | 股票-医疗保健 | 1.81% | -0.30% | — | |
| 14 | ELV | Elevance Health Inc | 股票-医疗保健 | 1.80% | +0.21% | — | |
| 15 | ARGX | Argenx Se - Adr | 股票-医疗保健 | 1.78% | -0.44% | +37.93% | |
| 16 | IRON | Disc Medicine Inc | 股票-其他 | 1.59% | -0.91% | +4.90% | |
| 17 | SPRY | Ars Pharmaceuticals Inc | 股票-其他 | 1.55% | -0.12% | — | |
| 18 | ✓ | Third Harmonic Bio Inc | 股票-其他 | 1.48% | — | — | |
| 19 | NTRA | Natera Inc | 股票-医疗保健 | 1.47% | +0.26% | -23.56% | |
| 20 | TMO | Thermo Fisher Scientific Inc | 股票-医疗保健 | 1.44% | +0.38% | — | |
| 21 | VRTX | Vertex Pharmaceuticals Inc | 股票-医疗保健 | 1.40% | — | +23.06% | |
| 22 | SWTXUSD | Springworks Therapeutics Inc | 股票-其他 | 1.27% | — | — | |
| 23 | NBIX | Neurocrine Biosciences Inc | 股票-医疗保健 | 1.22% | — | +5.93% | |
| 24 | ALNY | Alnylam Pharmaceuticals Inc | 股票-医疗保健 | 1.20% | -0.71% | — | |
| 25 | PCVX | Vaxcyte Inc | 股票-其他 | 1.19% | — | -25.35% | |
| 26 | KROS | Keros Therapeutics Inc | 股票-其他 | 1.14% | -0.02% | — | |
| 27 | CRNX | Crinetics Pharmaceuticals In | 股票-其他 | 1.13% | -0.04% | -7.52% | |
| 28 | UNH | Unitedhealth Group Inc | 股票-医疗保健 | 1.13% | +1.33% | NEW | |
| 29 | AVBP | Arrivent Biopharma Inc | 股票-其他 | 1.11% | +0.53% | — | |
| 30 | ICLR | ICON Public Limited Company | 股票-医疗保健 | 1.08% | — | — | |
| 31 | 430 | Terns Pharmaceuticals Inc | 股票-其他 | 1.02% | — | — | |
| 32 | APLSUSD | Apellis Pharmaceuticals Inc | 股票-其他 | 0.99% | — | -10.02% | |
| 33 | EVH | Evolent Health Inc - A | 股票-其他 | 0.98% | — | — | |
| 34 | XTNT | Xtant Medical Holdings Inc | 股票-其他 | 0.91% | — | — | |
| 35 | SIBN | Si-bone Inc | 股票-其他 | 0.89% | — | +1.62% | |
| 36 | CYTK | Cytokinetics Inc | 股票-医疗保健 | 0.87% | +0.04% | NEW | |
| 37 | AMGN | Amgen Inc | 股票-医疗保健 | 0.83% | -0.29% | EXIT | |
| 38 | PRLD | Prelude Therapeutics Inc | 股票-其他 | 0.82% | +0.60% | — | |
| 39 | VRNA | Verona Pharma PLC - Adr | 股票-其他 | 0.82% | — | -15.78% | |
| 40 | QTTB | Q32 Bio Inc | 股票-其他 | 0.80% | +0.68% | — | |
| 41 | ITGR | Integer Holdings CORP | 股票-医疗保健 | 0.80% | — | — | |
| 42 | GERN | Geron CORP | 股票-其他 | 0.80% | — | -26.09% | |
| 43 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 0.78% | +0.17% | +10.08% | |
| 44 | XENE | Xenon Pharmaceuticals Inc | 股票-其他 | 0.66% | -0.26% | +56.79% | |
| 45 | DXCM | Dexcom Inc | 股票-医疗保健 | 0.65% | — | +106.63% | |
| 46 | ✓ | Ikena Oncology Inc | 股票-其他 | 0.63% | -0.45% | EXIT | |
| 47 | RYTM | Rhythm Pharmaceuticals Inc | 股票-其他 | 0.57% | +0.11% | — | |
| 48 | RNAGBP | Avidity Biosciences Inc | 股票-其他 | 0.57% | — | -28.93% | |
| 49 | EXK | Exact Sciences CORP | 股票-原材料 | 0.56% | — | +378.93% | |
| 50 | NPCE | Neuropace Inc | 股票-其他 | 0.51% | -0.11% | -14.93% |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | ALNY | Alnylam Pharmaceuticals Inc | +1.2% | NEW | 新建仓 |
| 2 | LLY | Eli Lilly & Co | +0.9% | -6.43% | 减仓 |
| 3 | BSX | Boston Scientific CORP | +0.9% | — | 不变 |
| 4 | THC | Tenet Healthcare CORP | +0.8% | — | 不变 |
| 5 | ITGR | Integer Holdings CORP | +0.8% | NEW | 新建仓 |
| 6 | ELVN | Enliven Therapeutics Inc | +0.8% | -11.54% | 减仓 |
| 7 | ISRG | Intuitive Surgical Inc | +0.7% | — | 不变 |
| 8 | ARGX | Argenx Se - Adr | +0.7% | +37.93% | 加仓 |
| 9 | IONS | Ionis Pharmaceuticals Inc | +0.6% | +17.85% | 加仓 |
| 10 | BIIB | Biogen Inc | +0.6% | — | 不变 |
| 11 | SRPT | Sarepta Therapeutics Inc | +0.5% | -0.22% | 减仓 |
| 12 | AMGN | Amgen Inc | +0.5% | +112.78% | 加仓 |
| 13 | UNH | Unitedhealth Group Inc | +0.5% | +60.00% | 加仓 |
| 14 | ✓ | Third Harmonic Bio Inc | +0.5% | — | 不变 |
| 15 | VRTX | Vertex Pharmaceuticals Inc | +0.5% | +23.06% | 加仓 |
| 16 | EXK | Exact Sciences CORP | +0.4% | +378.93% | 加仓 |
| 17 | VIR | Vir Biotechnology Inc | +0.3% | +262.52% | 加仓 |
| 18 | DXCM | Dexcom Inc | +0.3% | +106.63% | 加仓 |
| 19 | ✓ | Adc Therapeutics SA | +0.3% | NEW | 新建仓 |
| 20 | ✓ | Merus N V | +0.2% | NEW | 新建仓 |
| 21 | CGEM | Cullinan Therapeutics Inc | +0.2% | +121.72% | 加仓 |
| 22 | SOLV | Solventum CORP | +0.2% | NEW | 新建仓 |
| 23 | MRK | Merck & Co. Inc. | 0% | — | 不变 |
| 24 | PRLD | Prelude Therapeutics Inc | -0.1% | — | 不变 |
| 25 | PCVX | Vaxcyte Inc | -0.1% | -25.35% | 减仓 |
| 26 | SIBN | Si-bone Inc | -0.1% | +1.62% | 加仓 |
| 27 | SPRY | Ars Pharmaceuticals Inc | -0.2% | — | 不变 |
| 28 | VRNA | Verona Pharma PLC - Adr | -0.2% | -15.78% | 减仓 |
| 29 | VTYXUSD | Ventyx Biosciences Inc | -0.2% | EXIT | 清仓 |
| 30 | TORCEUR | Adicet Bio Inc | -0.2% | — | 不变 |
| 31 | VSTM | Verastem Inc | -0.2% | — | 不变 |
| 32 | SWTXUSD | Springworks Therapeutics Inc | -0.3% | — | 不变 |
| 33 | ✓ | -0.3% | EXIT | 清仓 | |
| 34 | ALXO | Alx Oncology Holdings Inc | -0.3% | -30.30% | 减仓 |
| 35 | IRON | Disc Medicine Inc | -0.4% | +4.90% | 加仓 |
| 36 | CMPX | Compass Therapeutics Inc | -0.4% | — | 不变 |
| 37 | KNTEUSD | Kinnate Biopharma Inc | -0.4% | EXIT | 清仓 |
| 38 | ARWR | Arrowhead Pharmaceuticals In | -0.4% | EXIT | 清仓 |
| 39 | KROS | Keros Therapeutics Inc | -0.4% | — | 不变 |
| 40 | NPCE | Neuropace Inc | -0.5% | -14.93% | 减仓 |
| 41 | JANX | Janux Therapeutics Inc | -0.5% | -30.31% | 减仓 |
| 42 | PRAX | Praxis Precision Medicines I | -0.5% | EXIT | 清仓 |
| 43 | APLSUSD | Apellis Pharmaceuticals Inc | -0.6% | -10.02% | 减仓 |
| 44 | EVH | Evolent Health Inc - A | -0.6% | — | 不变 |
| 45 | APGE | Apogee Therapeutics Inc | -0.6% | -47.26% | 减仓 |
| 46 | XTNT | Xtant Medical Holdings Inc | -0.7% | — | 不变 |
| 47 | ESPR | Esperion Therapeutics Inc | -0.7% | EXIT | 清仓 |
| 48 | SRRK | Scholar Rock Holding CORP | -1% | -69.94% | 减仓 |
| 49 | NVLSEUR | Alpine Immune Sciences Inc | -2% | EXIT | 清仓 |
| 50 | BMRN | Biomarin Pharmaceutical Inc | -2% | -97.96% | 减仓 |
根据 SEC 官方 Form 13F 申报备案，Orbimed Advisors LLC 在 Q2 2024 季度的美股持仓总市值约为 US$53.7亿，共申报了 110 个公开持股仓位。
在 Q2 2024 季度，Orbimed Advisors LLC 按市值排列的前三大核心持股分别为：SVA (6.7%)、LLY (6.0%)、EWTX (5.3%)。其中最大持股仓位 SVA 占据整体投资组合约 6.7% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
ALNY
市值: US$6082.3万
本季最大获利了结 / 清仓标的
NVLSEUR
前期市值: US$1.1亿
在 Q2 2024 季度中，Orbimed Advisors LLC 共进行了 35 项持仓异动，包含新建仓 5 个仓位、加仓 11 个仓位、减仓 12 个仓位以及清仓 7 个仓位。 其中最大新建仓标的为 ALNY。 本季清仓仓位包含 NVLSEUR。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。