13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
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CIK: 0001009258
申报总市值
US$95.9亿
US$95.9亿
152 檔
26.9%
根据最新整理的 13F 季度数据集，Deerfield Management Company, L.p. 于 Q3 2025 结束时的管理资产规模为 US$95.9亿。该机构在本季度申报了 152 档美股持仓，呈现出该时期的主要投资地图。
在 Q3 2025，Deerfield Management Company, L.p. 操作展现出积极扩展与加仓意向。本季共新建仓 84 个新仓位，并对 25 个既有持股进行加仓（合计增持 109 档），相较减仓与清仓仓位显著占优。
在资产配置集中度方面，Deerfield Management Company, L.p. 的前 5 大核心持股（包含 NUVL, CNC, MERUS N V 等）合计占整体申报市值的 26.9%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | NUVL | Nuvalent Inc-a | 股票-其他 | 23.75% | +1.37% | — | |
| 2 | CNC | Centene CORP | 股票-医疗保健 | 4.93% | +0.99% | +183.99% | |
| 3 | ✓ | Merus N V | 股票-其他 | 4.38% | — | -9.98% | |
| 4 | VTRS | Viatris Inc | 股票-医疗保健 | 3.64% | +0.13% | +0.31% | |
| 5 | UTHR | United Therapeutics CORP | 股票-医疗保健 | 2.73% | -0.62% | -21.20% | |
| 6 | RVMD | Revolution Medicines Inc | 股票-医疗保健 | 2.60% | +2.03% | +7.87% | |
| 7 | INDV | Indivior Pharmaceuticals, Inc. | 股票-其他 | 2.57% | — | -33.88% | |
| 8 | MIRM 4 05-01-29债券 | Mirum Pharmaceuticals | 债券 | 2.57% | -2.47% | EXIT | |
| 9 | NBIX | Neurocrine Biosciences Inc | 股票-医疗保健 | 2.54% | -0.95% | EXIT | |
| 10 | COGT | Cogent Biosciences Inc | 股票-其他 | 1.98% | -2.09% | +242.89% | |
| 11 | IONS | Ionis Pharmaceuticals Inc | 股票-医疗保健 | 1.98% | -0.11% | — | |
| 12 | NAMS | NewAmsterdam Pharma Company N.V. | 股票-其他 | 1.85% | -0.10% | -16.60% | |
| 13 | VERA | Vera Therapeutics Inc | 股票-其他 | 1.62% | -0.02% | +8.75% | |
| 14 | BMY | Bristol-myers Squibb Co | 股票-医疗保健 | 1.61% | — | — | |
| 15 | AHCO | Adapthealth CORP | 股票-其他 | 1.57% | -0.36% | +15.88% | |
| 16 | LRMR | Larimar Therapeutics Inc | 股票-其他 | 1.51% | -0.76% | +44.16% | |
| 17 | BKD | Brookdale Senior Living Inc | 股票-其他 | 1.51% | +0.07% | -24.22% | |
| 18 | CPRX | Catalyst Pharmaceuticals Inc | 股票-医疗保健 | 1.50% | -1.15% | EXIT | |
| 19 | LEGN | Legend Biotech Corp-adr | 股票-其他 | 1.47% | +0.81% | — | |
| 20 | BCRX | Biocryst Pharmaceuticals Inc | 股票-其他 | 1.41% | -0.12% | +159.36% | |
| 21 | TNDM 1.5 03-15-29 2024债券 | Tandem Diabetes Care Inc | 债券 | 1.33% | — | +150.00% | |
| 22 | MRK | Merck & Co. Inc. | 股票-医疗保健 | 1.32% | — | +20.09% | |
| 23 | PFE | Pfizer Inc | 股票-医疗保健 | 1.29% | -0.25% | -23.28% | |
| 24 | IONS 1.75 06-15-28债券 | Ionis Pharmaceuticals In | 债券 | 1.26% | -0.10% | — | |
| 25 | CERT | Certara Inc | 股票-其他 | 1.26% | -0.02% | +71.66% | |
| 26 | INSP | Inspire Medical Systems Inc | 股票-医疗保健 | 1.19% | -1.04% | +648.35% | |
| 27 | SPRY | Ars Pharmaceuticals Inc | 股票-其他 | 1.15% | -0.08% | -22.84% | |
| 28 | INSM | Insmed Inc | 股票-医疗保健 | 1.04% | — | -32.78% | |
| 29 | BIO | Bio-rad Laboratories-a | 股票-医疗保健 | 0.97% | -0.05% | — | |
| 30 | NEO 0.25 01-15-28债券 | Neogenomics Inc | 债券 | 0.96% | -0.66% | — | |
| 31 | PHVS | Pharvaris N.V. | 股票-其他 | 0.93% | +0.18% | +21.07% | |
| 32 | IRON | Disc Medicine Inc | 股票-其他 | 0.93% | — | — | |
| 33 | IDYA | Ideaya Biosciences Inc | 股票-其他 | 0.89% | +0.46% | -45.01% | |
| 34 | BBOT | Bridgebio Oncology Therapeut | 股票-其他 | 0.86% | -0.13% | — | |
| 35 | NVST | Envista Holdings CORP | 股票-医疗保健 | 0.71% | -0.05% | +3.53% | |
| 36 | PRAX | Praxis Precision Medicines I | 股票-其他 | 0.68% | -0.30% | +22.41% | |
| 37 | CRMD | Cormedix Inc | 股票-其他 | 0.59% | — | — | |
| 38 | EHABUSD | Enhabit Inc | 股票-其他 | 0.58% | -0.79% | EXIT | |
| 39 | EMBC | Embecta CORP | 股票-医疗保健 | 0.56% | -0.17% | -4.70% | |
| 40 | LIVN 2.5 03-15-29债券 | Livanova PLC | 债券 | 0.56% | +0.01% | +37.12% | |
| 41 | CELC | Celcuity Inc | 股票-其他 | 0.55% | -0.73% | — | |
| 42 | CNMD | Conmed CORP | 股票-其他 | 0.55% | — | +8.56% | |
| 43 | ZBIO | Zenas Biopharma Inc | 股票-其他 | 0.53% | — | — | |
| 44 | NEO | Neogenomics Inc | 股票-医疗保健 | 0.52% | — | +107.05% | |
| 45 | ARWR | Arrowhead Pharmaceuticals In | 股票-医疗保健 | 0.52% | +0.02% | — | |
| 46 | DAWNGBX | Day One Biopharmaceuticals I | 股票-其他 | 0.51% | -0.94% | EXIT | |
| 47 | KYMR | Kymera Therapeutics Inc | 股票-其他 | 0.49% | -0.55% | EXIT | |
| 48 | CDNA | Caredx Inc | 股票-其他 | 0.49% | +0.14% | — | |
| 49 | ALNY | Alnylam Pharmaceuticals Inc | 股票-医疗保健 | 0.47% | -0.06% | -53.15% | |
| 50 | ACHC | Acadia Healthcare Co Inc | 股票-其他 | 0.45% | +0.14% | — |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | ✓ | Merus N V | +1.7% | -9.98% | 减仓 |
| 2 | CNC | Centene CORP | +1.7% | +183.99% | 加仓 |
| 3 | COGT | Cogent Biosciences Inc | +1.7% | +242.89% | 加仓 |
| 4 | VERA | Vera Therapeutics Inc | +1.1% | +8.75% | 加仓 |
| 5 | UTHR | United Therapeutics CORP | +1.1% | -21.20% | 加仓 |
| 6 | CERT | Certara Inc | +0.9% | +71.66% | 加仓 |
| 7 | BCRX | Biocryst Pharmaceuticals Inc | +0.6% | +159.36% | 加仓 |
| 8 | LRMR | Larimar Therapeutics Inc | +0.6% | +44.16% | 加仓 |
| 9 | INDV | Indivior Pharmaceuticals, Inc. | +0.6% | -33.88% | 减仓 |
| 10 | INSM | Insmed Inc | +0.4% | -32.78% | 加仓 |
| 11 | MIRM 4 05-01-29债券 | Mirum Pharmaceuticals | +0.3% | — | 不变 |
| 12 | LEGN | Legend Biotech Corp-adr | +0.3% | — | 加仓 |
| 13 | PHVS | Pharvaris N.V. | +0.3% | +21.07% | 加仓 |
| 14 | ZBIO | Zenas Biopharma Inc | +0.3% | — | 不变 |
| 15 | SION | Sionna Therapeutics Inc | +0.3% | — | 加仓 |
| 16 | RVMD | Revolution Medicines Inc | +0.3% | +7.87% | 加仓 |
| 17 | PRAX | Praxis Precision Medicines I | +0.2% | +22.41% | 加仓 |
| 18 | NAMS | NewAmsterdam Pharma Company N.V. | +0.2% | -16.60% | 加仓 |
| 19 | KYMR | Kymera Therapeutics Inc | +0.2% | -12.36% | 减仓 |
| 20 | IRON | Disc Medicine Inc | +0.2% | — | 加仓 |
| 21 | BBNX | Beta Bionics Inc | +0.1% | — | 加仓 |
| 22 | TOI | Oncology Institute Inc/the | +0.1% | — | 不变 |
| 23 | DAWNGBX | Day One Biopharmaceuticals I | +0.1% | +26.38% | 加仓 |
| 24 | GPCR | Structure Therapeutics Inc | 0% | — | 不变 |
| 25 | NVST | Envista Holdings CORP | 0% | +3.53% | 加仓 |
| 26 | SYRE | Spyre Therapeutics Inc | 0% | — | 加仓 |
| 27 | ALEC | Alector Inc | 0% | — | 不变 |
| 28 | FHTX | Foghorn Therapeutics Inc | 0% | — | 不变 |
| 29 | CALC | Calcimedica Inc | 0% | — | 不变 |
| 30 | ANNX | Annexon Inc | 0% | — | 不变 |
| 31 | ✓ | Newamsterdam Pharma Company | — | — | 不变 |
| 32 | TOIIW | Oncology Institute Inc Cw-22 | — | — | 不变 |
| 33 | CYH | Community Health Systems Inc | — | -41.26% | 加仓 |
| 34 | QSIAW | Quantum-si Inc -cw27 | — | — | 不变 |
| 35 | SVRA | Savara Inc | 0% | — | 不变 |
| 36 | TWST | Twist Bioscience CORP | 0% | — | 不变 |
| 37 | ✓ | 0% | — | 不变 | |
| 38 | IMCR 2.5 02-01-30债券 | Immunocore Holdings | -0.1% | — | 不变 |
| 39 | PHR | Phreesia Inc | -0.1% | +10.07% | 加仓 |
| 40 | BIO | Bio-rad Laboratories-a | -0.1% | — | 不变 |
| 41 | EMBC | Embecta CORP | -0.1% | -4.70% | 减仓 |
| 42 | CPRX | Catalyst Pharmaceuticals Inc | -0.1% | +72.77% | 加仓 |
| 43 | DCGO | Docgo Inc | -0.2% | -6.45% | 减仓 |
| 44 | IDYA | Ideaya Biosciences Inc | -0.2% | -45.01% | 减仓 |
| 45 | IART | Integra Lifesciences Holding | -0.2% | — | 不变 |
| 46 | CNMD | Conmed CORP | -0.2% | +8.56% | 加仓 |
| 47 | TXG | 10x Genomics Inc-class A | -0.2% | +2211.19% | 减仓 |
| 48 | EHABUSD | Enhabit Inc | -0.3% | -0.67% | 减仓 |
| 49 | LNTH 2.625 12-15-27债券 | Lantheus Holdings Inc | -0.3% | — | 不变 |
| 50 | ALNY | Alnylam Pharmaceuticals Inc | -0.3% | -53.15% | 减仓 |
根据 SEC 官方 Form 13F 申报备案，Deerfield Management Company, L.p. 在 Q3 2025 季度的美股持仓总市值约为 US$95.9亿，共申报了 152 个公开持股仓位。
在 Q3 2025 季度，Deerfield Management Company, L.p. 按市值排列的前三大核心持股分别为：NUVL (23.8%)、CNC (4.9%)、MERUS N V (4.4%)。其中最大持股仓位 NUVL 占据整体投资组合约 23.8% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
IONS
市值: US$1.3亿
本季最大获利了结 / 清仓标的
IART 0.5 08-15-25
前期市值: US$1.7亿
在 Q3 2025 季度中，Deerfield Management Company, L.p. 共进行了 181 项持仓异动，包含新建仓 84 个仓位、加仓 25 个仓位、减仓 17 个仓位以及清仓 55 个仓位。 其中最大新建仓标的为 IONS。 本季清仓仓位包含 IART 0.5 08-15-25。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。