13F 申报指南13F 概念全攻略
什么是 SEC Form 13F 申报？美股机构大户持股全攻略
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
AlphaSMO 权威研究指南阅读专题
CIK: 0001791827
申报总市值
US$6.2亿
US$6.2亿
62 檔
35.7%
在 Q4 2024 的 13F 官方备案中，Avidity Partners Management LP 管理的美股投资组合规模来到 US$6.2亿，整体持股档数为 62 档。
在 Q4 2024，Avidity Partners Management LP 展现出较为审慎的避险与获利了结姿态。本季共减仓 46 个仓位并完全清仓 25 档持股，调降曝光的仓位数量高于加仓动作。
在资产配置集中度方面，Avidity Partners Management LP 的前 5 大核心持股（包含 DNTH, BSX, JANX 等）合计占整体申报市值的 35.7%，反映机构在主要关键仓位上的权重分布。
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | DNTH | Dianthus Therapeutics Inc | 股票-其他 | 6.15% | -2.91% | -1.52% | |
| 2 | BSX | Boston Scientific CORP | 股票-医疗保健 | 4.52% | -0.21% | -46.47% | |
| 3 | JANX | Janux Therapeutics Inc | 股票-其他 | 3.90% | — | +32.01% | |
| 4 | ARVN | Arvinas Inc | 股票-其他 | 3.87% | — | +37.47% | |
| 5 | NTRA | Natera Inc | 股票-医疗保健 | 3.48% | -0.36% | EXIT | |
| 6 | EXK | Exact Sciences CORP | 股票-原材料 | 3.33% | — | +2.55% | |
| 7 | ISRG | Intuitive Surgical Inc | 股票-医疗保健 | 3.32% | — | -56.28% | |
| 8 | CGON | Cg Oncology Inc | 股票-其他 | 3.09% | -1.75% | -33.71% | |
| 9 | UNH | Unitedhealth Group Inc | 股票-医疗保健 | 2.98% | -0.21% | EXIT | |
| 10 | NBIX | Neurocrine Biosciences Inc | 股票-医疗保健 | 2.95% | — | -52.09% | |
| 11 | IDYA | Ideaya Biosciences Inc | 股票-其他 | 2.84% | — | -17.94% | |
| 12 | JAZZ | Jazz Pharmaceuticals plc | 股票-医疗保健 | 2.84% | — | -45.59% | |
| 13 | MIRM | Mirum Pharmaceuticals Inc | 股票-其他 | 2.71% | — | -8.88% | |
| 14 | ACHC | Acadia Healthcare Co Inc | 股票-其他 | 2.56% | — | -33.20% | |
| 15 | GKOS | Glaukos CORP | 股票-医疗保健 | 2.50% | — | -50.71% | |
| 16 | DXCM | Dexcom Inc | 股票-医疗保健 | 2.43% | -0.06% | +32.50% | |
| 17 | TMO | Thermo Fisher Scientific Inc | 股票-医疗保健 | 2.28% | — | -34.99% | |
| 18 | HUM | Humana Inc | 股票-医疗保健 | 2.22% | — | -31.23% | |
| 19 | KYMR | Kymera Therapeutics Inc | 股票-其他 | 1.98% | — | — | |
| 20 | AVTR | Avantor Inc | 股票-医疗保健 | 1.96% | — | -23.32% | |
| 21 | SNDX | Syndax Pharmaceuticals Inc | 股票-其他 | 1.95% | — | -38.90% | |
| 22 | 260 | Centessa Pharmaceuticals-adr | 股票-其他 | 1.92% | — | -45.32% | |
| 23 | RVMD | Revolution Medicines Inc | 股票-医疗保健 | 1.92% | -0.30% | EXIT | |
| 24 | XENE | Xenon Pharmaceuticals Inc | 股票-其他 | 1.82% | — | -42.05% | |
| 25 | THC | Tenet Healthcare CORP | 股票-医疗保健 | 1.70% | — | -45.85% | |
| 26 | INSM | Insmed Inc | 股票-医疗保健 | 1.58% | — | -60.68% | |
| 27 | AXSM | Axsome Therapeutics Inc | 股票-医疗保健 | 1.56% | — | -36.51% | |
| 28 | 2655787D | Blueprint Medicines CORP | 股票-其他 | 1.51% | — | -43.94% | |
| 29 | DHR | Danaher CORP | 股票-医疗保健 | 1.51% | — | -29.47% | |
| 30 | RARE | Ultragenyx Pharmaceutical In | 股票-其他 | 1.45% | — | -53.19% | |
| 31 | ILMN | Illumina Inc | 股票-医疗保健 | 1.44% | — | -62.43% | |
| 32 | ABBV | Abbvie Inc | 股票-医疗保健 | 1.41% | — | -19.30% | |
| 33 | RCKT | Rocket Pharmaceuticals Inc | 股票-其他 | 1.30% | — | +40.63% | |
| 34 | BMY | Bristol-myers Squibb Co | 股票-医疗保健 | 1.19% | — | -18.25% | |
| 35 | TMDX | Transmedics Group Inc | 股票-医疗保健 | 1.18% | — | +597.10% | |
| 36 | PHAT | Phathom Pharmaceuticals Inc | 股票-其他 | 1.11% | -0.21% | -22.96% | |
| 37 | SGRY | Surgery Partners Inc | 股票-其他 | 1.07% | — | -37.82% | |
| 38 | ORIC | Oric Pharmaceuticals Inc | 股票-其他 | 1.00% | — | -12.57% | |
| 39 | NAMS | NewAmsterdam Pharma Company N.V. | 股票-其他 | 0.89% | — | -60.21% | |
| 40 | INCY | Incyte CORP | 股票-医疗保健 | 0.88% | — | -57.94% | |
| 41 | CATX | Perspective Therapeutics Inc | 股票-其他 | 0.84% | -1.67% | -21.76% | |
| 42 | ASND | Ascendis Pharma A/S | 股票-其他 | 0.84% | — | -47.90% | |
| 43 | BHVN | Biohaven Ltd. | 股票-其他 | 0.82% | — | -52.06% | |
| 44 | ITCIEUR | Intra-cellular Therapies Inc | 股票-其他 | 0.80% | — | -58.37% | |
| 45 | VTLUSD | Immunic Inc | 股票-其他 | 0.78% | -1.51% | EXIT | |
| 46 | CNTX | Context Therapeutics Inc | 股票-其他 | 0.77% | -2.21% | +0.81% | |
| 47 | ORKA | Oruka Therapeutics Inc | 股票-其他 | 0.67% | +4.04% | -55.48% | |
| 48 | REGN | Regeneron Pharmaceuticals | 股票-医疗保健 | 0.59% | — | — | |
| 49 | BRKR | Bruker CORP | 股票-医疗保健 | 0.44% | — | — | |
| 50 | VERA | Vera Therapeutics Inc | 股票-其他 | 0.42% | — | — |
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | JANX | Janux Therapeutics Inc | +2.6% | +32.01% | 加仓 |
| 2 | DNTH | Dianthus Therapeutics Inc | +2.1% | -1.52% | 减仓 |
| 3 | ARVN | Arvinas Inc | +2% | +37.47% | 加仓 |
| 4 | DXCM | Dexcom Inc | +1.6% | +32.50% | 加仓 |
| 5 | EXK | Exact Sciences CORP | +1.3% | +2.55% | 加仓 |
| 6 | MIRM | Mirum Pharmaceuticals Inc | +1.3% | -8.88% | 减仓 |
| 7 | TMDX | Transmedics Group Inc | +1% | +597.10% | 加仓 |
| 8 | KYMR | Kymera Therapeutics Inc | +0.8% | — | 不变 |
| 9 | IDYA | Ideaya Biosciences Inc | +0.6% | -17.94% | 减仓 |
| 10 | REGN | Regeneron Pharmaceuticals | +0.6% | NEW | 新建仓 |
| 11 | RCKT | Rocket Pharmaceuticals Inc | +0.6% | +40.63% | 加仓 |
| 12 | BMY | Bristol-myers Squibb Co | +0.5% | -18.25% | 减仓 |
| 13 | BRKR | Bruker CORP | +0.4% | NEW | 新建仓 |
| 14 | VERA | Vera Therapeutics Inc | +0.4% | NEW | 新建仓 |
| 15 | BSX | Boston Scientific CORP | +0.4% | -46.47% | 减仓 |
| 16 | ABBV | Abbvie Inc | +0.4% | -19.30% | 减仓 |
| 17 | JAZZ | Jazz Pharmaceuticals plc | +0.4% | -45.59% | 减仓 |
| 18 | UNH | Unitedhealth Group Inc | +0.4% | -31.35% | 减仓 |
| 19 | AVTR | Avantor Inc | +0.3% | -23.32% | 减仓 |
| 20 | 2KZ0 | Kezar Life Sciences Inc | +0.3% | NEW | 新建仓 |
| 21 | NBIX | Neurocrine Biosciences Inc | +0.3% | -52.09% | 减仓 |
| 22 | ORIC | Oric Pharmaceuticals Inc | +0.2% | -12.57% | 减仓 |
| 23 | AKRO | Akero Therapeutics Inc | +0.2% | NEW | 新建仓 |
| 24 | QURE | uniQure N.V. | +0.2% | -67.04% | 减仓 |
| 25 | GKOS | Glaukos CORP | +0.2% | -50.71% | 减仓 |
| 26 | AXSM | Axsome Therapeutics Inc | +0.2% | -36.51% | 减仓 |
| 27 | 260 | Centessa Pharmaceuticals-adr | +0.2% | -45.32% | 减仓 |
| 28 | XENE | Xenon Pharmaceuticals Inc | +0.2% | -42.05% | 减仓 |
| 29 | DHR | Danaher CORP | +0.2% | -29.47% | 减仓 |
| 30 | NAMS | NewAmsterdam Pharma Company N.V. | +0.1% | -60.21% | 减仓 |
| 31 | TMO | Thermo Fisher Scientific Inc | +0.1% | -34.99% | 减仓 |
| 32 | HUM | Humana Inc | +0.1% | -31.23% | 减仓 |
| 33 | RVMD | Revolution Medicines Inc | +0.1% | -43.52% | 减仓 |
| 34 | VTLUSD | Immunic Inc | +0.1% | -3.62% | 减仓 |
| 35 | BLE0 | Bluebird Bio Inc | +0.1% | NEW | 新建仓 |
| 36 | SCYXEUR | Scynexis Inc | 0% | -15.17% | 减仓 |
| 37 | KPTIEUR | Karyopharm Therapeutics Inc | 0% | — | 不变 |
| 38 | CNTX | Context Therapeutics Inc | 0% | +0.81% | 加仓 |
| 39 | HYPR | Hyperfine Inc | 0% | — | 不变 |
| 40 | 2655787D | Blueprint Medicines CORP | 0% | -43.94% | 减仓 |
| 41 | ✓ | Caremax Inc | — | EXIT | 清仓 |
| 42 | ✓ | 0% | EXIT | 清仓 | |
| 43 | ASND | Ascendis Pharma A/S | -0.1% | -47.90% | 减仓 |
| 44 | ITCIEUR | Intra-cellular Therapies Inc | -0.1% | -58.37% | 减仓 |
| 45 | DYN | Dyne Therapeutics Inc | -0.1% | -41.82% | 减仓 |
| 46 | PRLD | Prelude Therapeutics Inc | -0.1% | EXIT | 清仓 |
| 47 | CGON | Cg Oncology Inc | -0.1% | -33.71% | 减仓 |
| 48 | TIL | Instil Bio Inc | -0.1% | EXIT | 清仓 |
| 49 | NTRA | Natera Inc | -0.1% | -59.78% | 减仓 |
| 50 | SYRS | Syros Pharmaceuticals Inc | -0.1% | EXIT | 清仓 |
根据 SEC 官方 Form 13F 申报备案，Avidity Partners Management LP 在 Q4 2024 季度的美股持仓总市值约为 US$6.2亿，共申报了 62 个公开持股仓位。
在 Q4 2024 季度，Avidity Partners Management LP 按市值排列的前三大核心持股分别为：DNTH (6.2%)、BSX (4.5%)、JANX (3.9%)。其中最大持股仓位 DNTH 占据整体投资组合约 6.2% 的权重。
精选 AlphaSMO 大户持股与内部人交易深度分析，提升投资决策胜率
完整解读 Form 13F 申报规范、1 亿美元门槛与 45 天延迟申报机制，学会如何追踪顶级对冲基金与机构法人持仓动向。
本季最大新建仓标的
REGN
市值: US$598.4万
本季最大获利了结 / 清仓标的
BMRN
前期市值: US$2249.3万
在 Q4 2024 季度中，Avidity Partners Management LP 共进行了 84 项持仓异动，包含新建仓 6 个仓位、加仓 7 个仓位、减仓 46 个仓位以及清仓 25 个仓位。 其中最大新建仓标的为 REGN。 本季清仓仓位包含 BMRN。
本页面所有持股数据均直接同步自美国证券交易委员会（SEC）EDGAR 官方系统之 13F-HR / 13F-HR/A 季度申报文件。AlphaSMO 通过机器解析 CUSIP 与个股对照，提供 100% 精准对齐的历史时序数据集，并支持 Schema.org 结构化数据格式。
解析公司高管、董事与 10% 大股东之 Form 4 内部人交易申报，掌握高管自家股票买卖第一手信号。
深入剖析 5% 股权申报门槛、13D 与 13G 之差异，以及最新 SEC 申报时程规范，洞察机构法人的激进投资动向。