| RA CAPITAL MANAGEMENT, L.P. | $4012.5万 | 0.43% |
| TCG Crossover Management, LLC | $3902.2万 | 1.12% |
| Versant Venture Management, LLC | $2749.5万 | 19.44% |
| Deep Track Capital, LP | $2144.2万 | 0.35% |
| Commodore Capital LP | $1965.2万 | 1.14% |
| Venrock Adviser, LLC | $1965.2万 | 0.73% |
| RTW INVESTMENTS, LP | $1965.2万 | 0.20% |
| Point72 Asset Management, L.P. | $1348.0万 | 0.02% |
| VANGUARD CAPITAL MANAGEMENT LLC | $1285.1万 | 0.00% |
| Balyasny Asset Management L.P. | $1134.0万 | 0.01% |
| MILLENNIUM MANAGEMENT LLC | $1054.8万 | 0.00% |
| Spruce Street Capital LP | $917.3万 | 2.21% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $856.4万 | 0.01% |
| Woodline Partners LP | $687.8万 | 0.03% |
| Seven Fleet Capital Management LP | $666.2万 | 2.11% |
| Trails Edge Capital Partners, LP | $553.7万 | 1.27% |
| DAFNA Capital Management LLC | $550.2万 | 1.25% |
| TWO SIGMA INVESTMENTS, LP | $535.9万 | 0.00% |
| BlackRock, Inc. | $344.5万 | 0.00% |
| Rock Springs Capital Management LP | $294.8万 | 0.17% |
| GEODE CAPITAL MANAGEMENT, LLC | $294.3万 | 0.00% |
| Casdin Capital, LLC | $277.6万 | 0.21% |
| Syncona Portfolio Ltd | $274.2万 | 10.66% |
| RENAISSANCE TECHNOLOGIES LLC | $204.9万 | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | $156.6万 | 0.00% |
| MARSHALL WACE, LLP | $152.2万 | 0.00% |
| STATE STREET CORP | $87.4万 | 0.00% |
| ACADIAN ASSET MANAGEMENT LLC | $62.7万 | 0.00% |
| NORTHERN TRUST CORP | $52.2万 | 0.00% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $51.2万 | 0.00% |
| GOLDMAN SACHS GROUP INC | $47.6万 | 0.00% |
| BANK OF AMERICA CORP /DE/ | $32.8万 | 0.00% |
| BARCLAYS PLC | $27.2万 | 0.00% |
| Squarepoint Ops LLC | $27.0万 | 0.00% |
| SUPERSTRING CAPITAL MANAGEMENT LP | $27.0万 | 0.19% |
| Brevan Howard Capital Management LP | $21.8万 | 0.00% |
| RAYMOND JAMES FINANCIAL INC | $20.6万 | 0.00% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $17.9万 | 0.00% |
| GSA CAPITAL PARTNERS LLP | $17.4万 | 0.01% |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $16.6万 | 0.00% |
| Invesco Ltd. | $14.0万 | 0.00% |
| AMERICAN CENTURY COMPANIES INC | $13.3万 | 0.00% |
| DIMENSIONAL FUND ADVISORS LP | $12.2万 | 0.00% |
| Cannon Global Investment Management, LLC | $11.1万 | 0.22% |
| OMERS ADMINISTRATION Corp | $10.8万 | 0.00% |
| Vanguard Global Advisers, LLC | $10.1万 | 0.00% |
| Tower Research Capital LLC (TRC) | $7.5万 | 0.00% |
| HarbourVest Partners LLC | $6.6万 | 0.06% |
| JANE STREET GROUP, LLC | $6.4万 | 0.00% |
| Parametrica Management Ltd | $6.3万 | 0.07% |
| MORGAN STANLEY | $5.9万 | 0.00% |
| PRUDENTIAL FINANCIAL INC | $5.7万 | 0.00% |
| XTX Topco Ltd | $5.1万 | 0.00% |
| Quadrant Private Wealth Management, LLC | $4.5万 | 0.01% |
| UBS Group AG | $3.2万 | 0.00% |
| CITADEL ADVISORS LLC | $3.0万 | 0.00% |
| Bank of New York Mellon Corp | $2.9万 | 0.00% |
| SIMPLEX TRADING, LLC | $2.0万 | 0.00% |
| FMR LLC | $2.0万 | 0.00% |
| Advisors Asset Management, Inc. | $1.9万 | 0.00% |
| ROYAL BANK OF CANADA | $9000.0 | 0.00% |
| Farther Finance Advisors, LLC | $5475.0 | 0.00% |
| SBI Securities Co., Ltd. | $2848.0 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | $1996.0 | 0.00% |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | $1145.0 | 0.00% |
| Advisory Services Network, LLC | $920.0 | 0.00% |
| Fortitude Family Office, LLC | $664.0 | 0.00% |
| JPMORGAN CHASE & CO | $233.0 | 0.00% |
| Arax Advisory Partners | $224.0 | 0.00% |
| WELLS FARGO & COMPANY/MN | $90.0 | 0.00% |
| Optiver Holding B.V. | $72.0 | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | $32.1 | 0.00% |
| Smartleaf Asset Management LLC | $2.0 | 0.00% |