| ORBIMED ADVISORS LLC | $104.8M | 2.15% |
| BlackRock, Inc. | $90.1M | 0.00% |
| STATE STREET CORP | $52.2M | 0.00% |
| ADAMS STREET PARTNERS LLC | $47.9M | 18.41% |
| VANGUARD CAPITAL MANAGEMENT LLC | $47.3M | 0.00% |
| PRICE T ROWE ASSOCIATES INC /MD/ | $42.7M | 0.00% |
| Vivo Capital, LLC | $41.0M | 3.41% |
| MORGAN STANLEY | $36.6M | 0.00% |
| Deep Track Capital, LP | $36.5M | 0.60% |
| WELLINGTON MANAGEMENT GROUP LLP | $33.9M | 0.01% |
| PERCEPTIVE ADVISORS LLC | $33.5M | 0.66% |
| Commodore Capital LP | $33.0M | 1.91% |
| Foresite Capital Management VI LLC | $26.8M | 5.82% |
| BRAIDWELL LP | $25.6M | 0.86% |
| GEODE CAPITAL MANAGEMENT, LLC | $25.1M | 0.00% |
| MPM BIOIMPACT LLC | $24.5M | 1.89% |
| GOLDMAN SACHS GROUP INC | $22.5M | 0.00% |
| Hood River Capital Management LLC | $19.5M | 0.20% |
| Boxer Capital Management, LLC | $16.1M | 2.11% |
| Polar Capital Holdings Plc | $15.7M | 0.06% |
| CITADEL ADVISORS LLC | $13.4M | 0.00% |
| Catalio Capital Management, LP | $13.0M | 2.73% |
| MILLENNIUM MANAGEMENT LLC | $12.7M | 0.01% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $11.2M | 0.00% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11.0M | 0.02% |
| EMERALD ADVISERS, LLC | $10.0M | 0.32% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9.8M | 0.00% |
| DCF Advisers, LLC | $9.3M | 2.49% |
| EVENTIDE ASSET MANAGEMENT, LLC | $8.0M | 0.13% |
| MARSHALL WACE, LLP | $8.0M | 0.01% |
| Blue Owl Capital Holdings LP | $8.0M | 2.14% |
| TWO SIGMA INVESTMENTS, LP | $7.9M | 0.01% |
| NORTHERN TRUST CORP | $7.4M | 0.00% |
| VANGUARD FIDUCIARY TRUST CO | $7.4M | 0.00% |
| EMERALD MUTUAL FUND ADVISERS TRUST | $6.7M | 0.33% |
| Nextech Invest, Ltd. | $6.6M | 0.46% |
| RA CAPITAL MANAGEMENT, L.P. | $6.6M | 0.07% |
| Logos Global Management LP | $6.6M | 0.33% |
| DIADEMA PARTNERS LP | $5.1M | 0.87% |
| JANE STREET GROUP, LLC | $4.5M | 0.00% |
| UBS Group AG | $4.2M | 0.00% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $4.1M | 0.02% |
| SPHERA FUNDS MANAGEMENT LTD. | $3.6M | 0.58% |
| BARCLAYS PLC | $3.6M | 0.00% |
| BANK OF AMERICA CORP /DE/ | $3.5M | 0.00% |
| Spruce Street Capital LP | $3.4M | 0.81% |
| SEB Asset Management AB | $3.3M | 0.01% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2.8M | 0.00% |
| Bank of New York Mellon Corp | $2.7M | 0.00% |
| Polymer Capital Management (HK) LTD | $2.7M | 0.23% |
| Brevan Howard Capital Management LP | $2.5M | 0.02% |
| Caption Management, LLC | $2.3M | 0.01% |
| Nuveen, LLC | $2.2M | 0.00% |
| Jump Financial, LLC | $2.2M | 0.03% |
| Informed Momentum Co LLC | $2.0M | 0.23% |
| JPMORGAN CHASE & CO | $1.9M | 0.00% |
| VICTORY CAPITAL MANAGEMENT INC | $1.9M | 0.00% |
| Squarepoint Ops LLC | $1.8M | 0.00% |
| TD Asset Management Inc | $1.8M | 0.00% |
| Avidity Partners Management LP | $1.7M | 0.34% |
| Rafferty Asset Management, LLC | $1.6M | 0.01% |
| Tidal Investments LLC | $1.6M | 0.00% |
| Tema ETFs LLC | $1.6M | 0.11% |
| Aquatic Capital Management LLC | $1.5M | 0.04% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.5M | 0.00% |
| F/m Investments LLC | $1.5M | 0.10% |
| RAYMOND JAMES FINANCIAL INC | $1.5M | 0.00% |
| VOYA INVESTMENT MANAGEMENT LLC | $1.5M | 0.00% |
| ADAR1 Capital Management, LLC | $1.3M | 0.08% |
| Propel Bio Management, LLC | $1.3M | 0.79% |
| Connor, Clark & Lunn Investment Management Ltd. | $1.2M | 0.00% |
| Seven Fleet Capital Management LP | $1.2M | 0.38% |
| RENAISSANCE TECHNOLOGIES LLC | $1.2M | 0.00% |
| RHUMBLINE ADVISERS | $1.1M | 0.00% |
| TOWERVIEW LLC | $1.0M | 0.66% |
| ACADIAN ASSET MANAGEMENT LLC | $1.0M | 0.00% |
| ALPS ADVISORS INC | $997.7K | 0.00% |
| JACKSON SQUARE CAPITAL, LLC | $933.0K | 0.20% |
| Persistent Asset Partners Ltd | $907.8K | 0.34% |
| SEI INVESTMENTS CO | $890.2K | 0.00% |
| Ancora Advisors LLC | $801.3K | 0.02% |
| DEUTSCHE BANK AG\ | $797.0K | 0.00% |
| PROFUND ADVISORS LLC | $734.9K | 0.03% |
| SEVEN GRAND MANAGERS, LLC | $731.5K | 0.05% |
| Hikari Power Ltd | $731.0K | 0.06% |
| Vanguard Global Advisers, LLC | $697.7K | 0.00% |
| Creative Planning | $629.6K | 0.00% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $605.9K | 0.00% |
| FRANKLIN RESOURCES INC | $571.8K | 0.00% |
| Invesco Ltd. | $559.0K | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $548.4K | 0.00% |
| SG Americas Securities, LLC | $518.0K | 0.00% |
| SIMPLEX TRADING, LLC | $508.0K | 0.00% |
| XTX Topco Ltd | $501.9K | 0.01% |
| Qube Research & Technologies Ltd | $486.1K | 0.00% |
| AVITY INVESTMENT MANAGEMENT INC. | $485.7K | 0.04% |
| MetLife Investment Management, LLC | $484.3K | 0.00% |
| Virtus Investment Advisers, LLC | $476.6K | 0.13% |
| ALLIANCEBERNSTEIN L.P. | $475.4K | 0.00% |
| Composition Wealth, LLC | $438.9K | 0.01% |
| Optimize Financial Inc | $410.5K | 0.20% |
| TUDOR INVESTMENT CORP ET AL | $402.2K | 0.00% |
| China Universal Asset Management Co., Ltd. | $397.3K | 0.03% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $390.6K | 0.01% |
| WINTON GROUP Ltd | $389.5K | 0.01% |
| INTECH INVESTMENT MANAGEMENT LLC | $342.1K | 0.00% |
| WELLS FARGO & COMPANY/MN | $341.9K | 0.00% |
| Quantinno Capital Management LP | $336.2K | 0.00% |
| Three Bridge Wealth Advisors, LLC | $327.3K | 0.09% |
| Simplify Asset Management Inc. | $296.1K | 0.00% |
| Burkehill Global Management, LP | $292.6K | 0.01% |
| Corient Private Wealth LLC | $289.6K | 0.00% |
| NEW YORK STATE COMMON RETIREMENT FUND | $264.8K | 0.00% |
| Police & Firemen's Retirement System of New Jersey | $263.6K | 0.00% |
| Sowell Financial Services LLC | $219.5K | 0.01% |
| CITIGROUP INC | $217.2K | 0.00% |
| E Fund Management Co., Ltd. | $207.1K | 0.01% |
| AXQ CAPITAL, LP | $200.9K | 0.03% |
| ProShare Advisors LLC | $190.6K | 0.00% |
| SHELTON WEALTH MANAGEMENT, LLC | $179.5K | 0.08% |
| Virtu Financial LLC | $175.0K | 0.01% |
| PRUDENTIAL FINANCIAL INC | $170.8K | 0.00% |
| OneDigital Investment Advisors LLC | $156.8K | 0.00% |
| DRW Securities, LLC | $154.8K | 0.00% |
| Truvestments Capital LLC | $150.1K | 0.03% |
| WHITTIER TRUST CO OF NEVADA INC | $150.0K | 0.00% |
| Ghisallo Capital Management LLC | $146.3K | 0.00% |
| Caitong International Asset Management Co., Ltd | $146.1K | 0.03% |
| Tower Research Capital LLC (TRC) | $137.0K | 0.00% |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $117.0K | 0.00% |
| ROTHSCHILD INVESTMENT LLC | $109.7K | 0.01% |
| Russell Investments Group, Ltd. | $99.4K | 0.00% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $89.5K | 0.00% |
| Legal & General Group Plc | $83.1K | 0.00% |
| Ameritas Investment Partners, Inc. | $69.5K | 0.00% |
| Mirae Asset Global Investments Co., Ltd. | $63.0K | 0.00% |
| FMR LLC | $52.1K | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $51.2K | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | $38.1K | 0.00% |
| Western Pacific Wealth Management, LP | $29.3K | 0.03% |
| GF FUND MANAGEMENT CO. LTD. | $24.4K | 0.00% |
| CWM, LLC | $18.1K | 0.00% |
| US BANCORP \DE\ | $16.1K | 0.00% |
| SBI Securities Co., Ltd. | $14.7K | 0.00% |
| MEEDER ASSET MANAGEMENT INC | $11.0K | 0.00% |
| OSAIC HOLDINGS, INC. | $10.8K | 0.00% |
| GAMMA Investing LLC | $8.8K | 0.00% |
| Sterling Capital Management LLC | $6.1K | 0.00% |
| QUADRANT CAPITAL GROUP LLC | $3.9K | 0.00% |
| BNP PARIBAS FINANCIAL MARKETS | $3.1K | 0.00% |