BC
Boxer Capital Management, LLC 13F Holdings (63 Positions, Q2 2026)
Boxer Capital Management, LLCCIK: 0002018299
Sector-focusedMomentum followerQuality / disciplined sizing
Total reported value
$1.3B
Reporting period: 2026-06-30 · Number of holdings: 63
Boxer Capital Management, LLC disclosed 63 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $1.3B and a quarterly turnover rate of 60.5%.
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Personality snowflake
- Concentration
- 35.51
- Portfolio Stability
- 60.54
- Momentum
- 100
- Sector conviction
- 100
- Diversification
- 100
- Sizing Uniformity
- 78.4
Boxer Capital Management, LLC's disclosed holdings carry a Herfindahl concentration index of 0.089 — mathematically equivalent to about 11 equally-sized positions, well below its 63 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 2.16), with a handful of outsized bets alongside many smaller positions.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 11% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govTrim TNGX
0.0% $112.5M
Add QURE
+127.1% $58.4M
Add ABVX
+202.5% $58.4M
New buy QTTB
Sold out 430
Trim KOD
+8.6% $5.7M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | TNGX | Tango Therapeutics Inc | Stock-Other | 25.61% | -4.26% | — | |
| 2 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 7.05% | +0.67% | — | |
| 3 | ABVX | Abivax Sa-adr | Stock-Other | 6.07% | +3.15% | +202.50% | |
| 4 | QURE | uniQure N.V. | Stock-Other | 5.21% | +3.79% | +127.08% | |
| 5 | KOD | Kodiak Sciences Inc | Stock-Other | 4.34% | -2.47% | +8.57% | |
| 6 | KYMR | Kymera Therapeutics Inc | Stock-Other | 3.71% | +0.11% | +30.39% | |
| 7 | DFTX | Definium Therapeutics Inc | Stock-Other | 3.54% | +2.05% | +66.83% | |
| 8 | REPL | Replimune Group Inc | Stock-Other | 3.32% | +2.14% | +238.98% | |
| 9 | CELC | Celcuity Inc | Stock-Other | 3.28% | -0.09% | +85.12% | |
| 10 | QTTB | Q32 Bio Inc | Stock-Other | 3.02% | +3.02% | NEW | |
| 11 | CAPR | Capricor Therapeutics Inc | Stock-Other | 2.53% | +0.18% | +136.47% | |
| 12 | PGEN | Precigen Inc | Stock-Other | 2.21% | +0.43% | +47.14% | |
| 13 | CORT | Corcept Therapeutics Inc | Stock-Healthcare | 2.20% | +0.88% | +34.20% | |
| 14 | SRZN | Surrozen Inc | Stock-Other | 2.03% | -0.90% | +44.29% | |
| 15 | PTGX | Protagonist Therapeutics Inc | Stock-Other | 1.57% | -0.78% | — | |
| 16 | VIR | Vir Biotechnology Inc | Stock-Other | 1.43% | -0.77% | — | |
| 17 | PCVX | Vaxcyte Inc | Stock-Other | 1.42% | -1.06% | — | |
| 18 | URGN | UroGen Pharma Ltd. | Stock-Other | 1.39% | +0.21% | — | |
| 19 | CRVS | Corvus Pharmaceuticals Inc | Stock-Other | 1.24% | -0.87% | — | |
| 20 | PTCT | Ptc Therapeutics Inc | Stock-Healthcare | 1.23% | -0.56% | — | |
| 21 | PRAX | Praxis Precision Medicines I | Stock-Other | 1.17% | -0.80% | — | |
| 22 | AMLX | Amylyx Pharmaceuticals Inc | Stock-Other | 1.08% | -0.38% | — | |
| 23 | OCUL | Ocular Therapeutix Inc | Stock-Other | 0.96% | +0.57% | +271.43% | |
| 24 | IRD | Opus Genetics Inc | Stock-Other | 0.87% | -0.47% | +25.11% | |
| 25 | PALI | Palisade Bio Inc | Stock-Other | 0.76% | -0.34% | — | |
| 26 | APGE | Apogee Therapeutics Inc | Stock-Other | 0.70% | -0.07% | — | |
| 27 | SYRE | Spyre Therapeutics Inc | Stock-Other | 0.67% | +0.67% | NEW | |
| 28 | COGT | Cogent Biosciences Inc | Stock-Other | 0.66% | -0.48% | — | |
| 29 | CYTK | Cytokinetics Inc | Stock-Healthcare | 0.64% | -0.23% | — | |
| 30 | RLAY | Relay Therapeutics Inc | Stock-Other | 0.63% | +0.63% | NEW | |
| 31 | ✓ | Crescent Biopharma Inc. | Stock-Other | 0.62% | -0.47% | — | |
| 32 | CTNM | Contineum Therapeutics Inc-a | Stock-Other | 0.61% | -0.24% | — | |
| 33 | KZIA | Kazia Therapeutics-spon Adr | Stock-Other | 0.59% | +0.59% | NEW | |
| 34 | STTK | Shattuck Labs Inc | Stock-Other | 0.52% | +0.52% | NEW | |
| 35 | AVTX | Avalo Therapeutics Inc | Stock-Other | 0.52% | -0.07% | +25.00% | |
| 36 | FBRX | Forte Biosciences Inc | Stock-Other | 0.44% | +0.44% | NEW | |
| 37 | RLMD | Relmada Therapeutics Inc | Stock-Other | 0.44% | -0.33% | — | |
| 38 | MLTX | Moonlake Immunotherapeutics | Stock-Other | 0.40% | -0.27% | — | |
| 39 | ✓ | Zura Bio LTD | Stock-Other | 0.40% | -0.30% | — | |
| 40 | HELP | Cybin Inc | Stock-Other | 0.39% | -0.01% | +23.44% | |
| 41 | ✓ | Stock-Other | 0.39% | +0.39% | NEW | ||
| 42 | ✓ | Immatics NV | Stock-Other | 0.36% | +0.36% | NEW | |
| 43 | FTH | Faeth Therapeutics Inc | Stock-Other | 0.34% | +0.34% | NEW | |
| 44 | GPCR | Structure Therapeutics Inc | Stock-Other | 0.30% | -0.17% | — | |
| 45 | ORIC | Oric Pharmaceuticals Inc | Stock-Other | 0.29% | — | +98.30% | |
| 46 | ANTX | An2 Therapeutics Inc | Stock-Other | 0.27% | -0.07% | — | |
| 47 | NMRA | Neumora Therapeutics Inc | Stock-Other | 0.26% | +0.26% | NEW | |
| 48 | INO | Inovio Pharmaceuticals Inc | Stock-Other | 0.24% | -0.30% | +20.04% | |
| 49 | ALLO | Allogene Therapeutics Inc | Stock-Other | 0.23% | -0.63% | -44.95% | |
| 50 | SLDB | Solid Biosciences Inc | Stock-Other | 0.23% | -0.05% | — |
1–50 of 63
* This report is exclusively curated by the AlphaSMO team. AlphaSMO is the web's most authoritative 13F / Inside Trader database, delivering precise insider trading and institutional holdings insights.
Portfolio Performance
Performance for Q3 2026
+15.5%
Performance Last 4 Quarters
+174.3%
- Stdev
- +48.7%
- Beta
- +0.44
- Alpha
- +81.6%
- Max Drawdown
- -7.8%
- Annualized Perf
- +117%
- Batting Avg vs S&P
- +61.1%
- Sortino
- +5.42
- Stutzer
- +0.59
- Treynor
- +2.04
- Sterling
- +6.58
- Calmar
- +15.05
- Information Ratio
- +1.45
- Tracking Error
- +49%
- Stdev Down
- +16.6%
- Winning Months %
- +77.8%
- Losing Months %
- +22.2%
- Best 12 Months
- +225.7%
- Worst 12 Months
- +103.9%
- Efficiency Ratio
- +1.05
- Sharpe
- +1.85
- Stdev Sectors
- 0%
- Skewness
- +0.79
- Kurtosis
- +0.79
- Upside Potential
- +6.91
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
Holding changes this quarter
Boxer Capital Management, LLC's most significant position changes for 2026-06-30: New buy: Q32 Bio Inc (QTTB); Sold out: Terns Pharmaceuticals Inc (430); New buy: Spyre Therapeutics Inc (SYRE); New buy: Relay Therapeutics Inc (RLAY); New buy: Kazia Therapeutics-spon Adr (KZIA).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | QURE | uniQure N.V. | +3.8% | +127.08% | Add |
| 2 | ABVX | Abivax Sa-adr | +3.2% | +202.50% | Add |
| 3 | QTTB | Q32 Bio Inc | +3% | NEW | New buy |
| 4 | REPL | Replimune Group Inc | +2.1% | +238.98% | Add |
| 5 | DFTX | Definium Therapeutics Inc | +2.1% | +66.83% | Add |
| 6 | CORT | Corcept Therapeutics Inc | +0.9% | +34.20% | Add |
| 7 | RVMD | Revolution Medicines Inc | +0.7% | — | Unchanged |
| 8 | SYRE | Spyre Therapeutics Inc | +0.7% | NEW | New buy |
| 9 | RLAY | Relay Therapeutics Inc | +0.6% | NEW | New buy |
| 10 | KZIA | Kazia Therapeutics-spon Adr | +0.6% | NEW | New buy |
| 11 | OCUL | Ocular Therapeutix Inc | +0.6% | +271.43% | Add |
| 12 | STTK | Shattuck Labs Inc | +0.5% | NEW | New buy |
| 13 | FBRX | Forte Biosciences Inc | +0.4% | NEW | New buy |
| 14 | PGEN | Precigen Inc | +0.4% | +47.14% | Add |
| 15 | ✓ | +0.4% | NEW | New buy | |
| 16 | ✓ | Immatics NV | +0.4% | NEW | New buy |
| 17 | FTH | Faeth Therapeutics Inc | +0.3% | NEW | New buy |
| 18 | NMRA | Neumora Therapeutics Inc | +0.3% | NEW | New buy |
| 19 | URGN | UroGen Pharma Ltd. | +0.2% | — | Unchanged |
| 20 | MPLT | Maplight Therapeutics Inc | +0.2% | NEW | New buy |
| 21 | CAPR | Capricor Therapeutics Inc | +0.2% | +136.47% | Add |
| 22 | EDSA | Edesa Biotech Inc | +0.1% | NEW | New buy |
| 23 | KYMR | Kymera Therapeutics Inc | +0.1% | +30.39% | Add |
| 24 | ORIC | Oric Pharmaceuticals Inc | — | +98.30% | Add |
| 25 | KPTI | Karyopharm Therapeutics Inc | — | — | Unchanged |
| 26 | SRZNW | Surrozen Inc-cw25 | — | — | Unchanged |
| 27 | HELP | Cybin Inc | 0% | +23.44% | Add |
| 28 | RGNX | Regenxbio Inc | 0% | — | Unchanged |
| 29 | NRIX | Nurix Therapeutics Inc | 0% | — | Unchanged |
| 30 | PEPG | Pepgen Inc | 0% | — | Unchanged |
| 31 | MIST | Milestone Pharmaceuticals In | 0% | — | Unchanged |
| 32 | SLDB | Solid Biosciences Inc | -0.1% | — | Unchanged |
| 33 | 4XC1 | Kalvista Pharmaceuticals Inc | -0.1% | EXIT | Sold out |
| 34 | LBRX | Lb Pharmaceuticals Inc | -0.1% | — | Unchanged |
| 35 | APGE | Apogee Therapeutics Inc | -0.1% | — | Unchanged |
| 36 | AVTX | Avalo Therapeutics Inc | -0.1% | +25.00% | Add |
| 37 | ANTX | An2 Therapeutics Inc | -0.1% | — | Unchanged |
| 38 | CELC | Celcuity Inc | -0.1% | +85.12% | Add |
| 39 | CLNN | Clene Inc | -0.1% | — | Unchanged |
| 40 | UPB | Upstream Bio Inc | -0.1% | — | Unchanged |
| 41 | IVVD | Invivyd Inc | -0.2% | — | Unchanged |
| 42 | GPCR | Structure Therapeutics Inc | -0.2% | — | Unchanged |
| 43 | CYTK | Cytokinetics Inc | -0.2% | — | Unchanged |
| 44 | SRPT | Sarepta Therapeutics Inc | -0.2% | — | Unchanged |
| 45 | CTNM | Contineum Therapeutics Inc-a | -0.2% | — | Unchanged |
| 46 | MLTX | Moonlake Immunotherapeutics | -0.3% | — | Unchanged |
| 47 | INO | Inovio Pharmaceuticals Inc | -0.3% | +20.04% | Add |
| 48 | ✓ | Zura Bio LTD | -0.3% | — | Unchanged |
| 49 | RLMD | Relmada Therapeutics Inc | -0.3% | — | Unchanged |
| 50 | PALI | Palisade Bio Inc | -0.3% | — | Unchanged |
1–50 of 66
Filing History
FAQ
What is Boxer Capital Management, LLC and what type of investor is it?
Boxer Capital Management, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $1.3B, spread across 63 disclosed positions.
What are Boxer Capital Management, LLC's largest equity positions?
Based on the latest 13F filing, Boxer Capital Management, LLC's top holdings by market value are:
1. Tango Therapeutics Inc (TNGX) — $340.0M (25.6%)
2. Revolution Medicines Inc (RVMD) — $93.6M (7.0%)
3. Abivax Sa-adr (ABVX) — $80.6M (6.1%)
4. uniQure N.V. (QURE) — $69.2M (5.2%)
5. Kodiak Sciences Inc (KOD) — $57.6M (4.3%)
What changes did Boxer Capital Management, LLC make in its most recent portfolio filing?
In the latest reported quarter, Boxer Capital Management, LLC made 33 notable position adjustments: 12 new positions were initiated, 17 existing holdings were added to, 1 positions were partially reduced, and 3 were completely exited. The largest of these moves: New buy: Q32 Bio Inc (QTTB); Sold out: Terns Pharmaceuticals Inc (430); New buy: Spyre Therapeutics Inc (SYRE); New buy: Relay Therapeutics Inc (RLAY); New buy: Kazia Therapeutics-spon Adr (KZIA)
What sectors does Boxer Capital Management, LLC focus on?
Boxer Capital Management, LLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
Boxer Capital Management, LLC returned an annualized 117.0% over the trailing 18 months — outperforming the S&P 500 by 81.6 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.44 (less volatile than the market) and a 61% quarterly batting average against the index.
Its portfolio is moderately concentrated and fast-trading, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has fallen from 100 to 61 over the past 4 quarters — a shift toward longer holding periods.
It has added to its TNGX position over the past two quarters (+$243.6M, now $340.0M), while trimming UPB over the same stretch (-$3.0M, still holding $1.0M).
Peer Institutions
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Sector conviction65.1
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CA
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GJ
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Developer Access
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REST API
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