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CIK: 0001482416
Total reported value
$604.3M
$604.3M
51 檔
23.4%
According to the latest 13F quarterly dataset, Sio Capital Management, LLC managed an equity portfolio of $604.3M at the end of Q4 2024, spanning 51 distinct U.S. exchange-listed positions.
In Q4 2024, Sio Capital Management, LLC displayed an active expansion posture, initiating 22 new positions and adding to 9 existing holdings, outstripping position reductions.
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ICLR | ICON Public Limited Company | Stock-Healthcare | 11.54% | -2.32% | — | |
| 2 | MMS | Maximus Inc | Stock-Industrials | 8.01% | -0.71% | +145.85% | |
| 3 | CI | THE Cigna Group | Stock-Healthcare | 7.61% | +2.63% | NEW | |
| 4 | LH | Labcorp Holdings Inc | Stock-Healthcare | 7.31% | — | -34.62% | |
| 5 | SNY | Sanofi-adr | Stock-Healthcare | 5.25% | +0.91% | — | |
| 6 | ZBH | Zimmer Biomet Holdings Inc | Stock-Healthcare | 5.20% | +1.06% | +37.09% | |
| 7 | DRUG | Bright Minds Biosciences Inc | Stock-Other | 4.58% | -0.04% | — | |
| 8 | AVR | Anteris Technologies Global | Stock-Other | 3.72% | +4.76% | — | |
| 9 | ANNX | Annexon Inc | Stock-Other | 3.42% | — | +65.16% | |
| 10 | TFX | Teleflex Inc | Stock-Healthcare | 3.34% | -1.63% | EXIT | |
| 11 | VTRS | Viatris Inc | Stock-Healthcare | 2.56% | +2.51% | NEW | |
| 12 | OGN | Organon & Co | Stock-Healthcare | 2.55% | -0.74% | EXIT | |
| 13 | VTYXUSD | Ventyx Biosciences Inc | Stock-Other | 2.49% | — | +105.22% | |
| 14 | ANIP | Ani Pharmaceuticals Inc | Stock-Other | 2.49% | -1.60% | — | |
| 15 | EMBC | Embecta CORP | Stock-Healthcare | 2.47% | -2.34% | EXIT | |
| 16 | VIR | Vir Biotechnology Inc | Stock-Other | 2.18% | -0.12% | — | |
| 17 | VXRT | Vaxart Inc | Stock-Other | 2.15% | — | -15.38% | |
| 18 | TARA | Protara Therapeutic Inc | Stock-Other | 2.14% | -0.26% | — | |
| 19 | CRGX | Cargo Therapeutics Inc | Stock-Other | 1.92% | — | +172.23% | |
| 20 | NMRA | Neumora Therapeutics Inc | Stock-Other | 1.90% | — | — | |
| 21 | SEPN | Septerna Inc | Stock-Other | 1.75% | — | — | |
| 22 | ✓ | Proqr Therapeutics N.v. | Stock-Other | 1.53% | -0.45% | EXIT | |
| 23 | PMVP | Pmv Pharmaceuticals Inc | Stock-Other | 1.52% | +0.03% | +11.14% | |
| 24 | IRON | Disc Medicine Inc | Stock-Other | 1.31% | -0.60% | EXIT | |
| 25 | CATBUSD | Astria Therapeutics Inc | Stock-Other | 1.27% | — | — | |
| 26 | IRWD | Ironwood Pharmaceuticals Inc | Stock-Other | 1.13% | — | — | |
| 27 | AORT | Artivion Inc | Stock-Other | 0.97% | +0.18% | NEW | |
| 28 | ERAS | Erasca Inc | Stock-Other | 0.96% | -0.01% | EXIT | |
| 29 | TYRA | Tyra Biosciences Inc | Stock-Other | 0.94% | +0.35% | -39.91% | |
| 30 | IDYA | Ideaya Biosciences Inc | Stock-Other | 0.89% | +2.96% | NEW | |
| 31 | ACOG | Alpha Cognition Inc | Stock-Other | 0.72% | — | — | |
| 32 | QTTB | Q32 Bio Inc | Stock-Other | 0.68% | — | — | |
| 33 | TELA | Tela Bio Inc | Stock-Other | 0.54% | +0.02% | — | |
| 34 | NUVB | Nuvation Bio Inc | Stock-Other | 0.50% | — | — | |
| 35 | CNTX | Context Therapeutics Inc | Stock-Other | 0.39% | -0.34% | EXIT | |
| 36 | ALEC | Alector Inc | Stock-Other | 0.33% | — | — | |
| 37 | ENTA | Enanta Pharmaceuticals Inc | Stock-Other | 0.29% | -0.07% | EXIT | |
| 38 | OVID | Ovid Therapeutics Inc | Stock-Other | 0.26% | +0.05% | — | |
| 39 | APRE | Aprea Therapeutics Inc | Stock-Other | 0.26% | — | — | |
| 40 | FHTX | Foghorn Therapeutics Inc | Stock-Other | 0.16% | -0.08% | EXIT | |
| 41 | CCCC | C4 Therapeutics Inc | Stock-Other | 0.16% | — | — | |
| 42 | AVTX | Avalo Therapeutics Inc | Stock-Other | 0.15% | — | — | |
| 43 | BOLD | Boundless Bio Inc | Stock-Other | 0.13% | -0.03% | EXIT | |
| 44 | ✓ | Nyxoah S A | Stock-Other | 0.11% | -0.02% | EXIT | |
| 45 | ✓ | Modular Med Inc | Stock-Other | 0.10% | — | +108.65% | |
| 46 | MESO | Mesoblast Ltd- Spon Adr | Stock-Other | 0.06% | — | — | |
| 47 | NXTCEUR | Nextcure Inc | Stock-Other | 0.03% | — | — | |
| 48 | HUMAW | Humacyte Inc-cw27 | Stock-Other | 0.03% | — | — | |
| 49 | 430 | Terns Pharmaceuticals Inc | Stock-Other | 0.02% | -0.08% | EXIT | |
| 50 | RCKTW | Rocket Pharmaceuticals In-27 | Stock-Other | — | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ICLR | ICON Public Limited Company | +11.5% | NEW | New buy |
| 2 | SNY | Sanofi-adr | +5.3% | NEW | New buy |
| 3 | DRUG | Bright Minds Biosciences Inc | +4.6% | NEW | New buy |
| 4 | CI | THE Cigna Group | +4% | +269.78% | Add |
| 5 | AVR | Anteris Technologies Global | +3.7% | NEW | New buy |
| 6 | VTRS | Viatris Inc | +2.6% | NEW | New buy |
| 7 | OGN | Organon & Co | +2.6% | NEW | New buy |
| 8 | ANIP | Ani Pharmaceuticals Inc | +2.5% | NEW | New buy |
| 9 | EMBC | Embecta CORP | +2.5% | NEW | New buy |
| 10 | MMS | Maximus Inc | +2.3% | +145.85% | Add |
| 11 | VIR | Vir Biotechnology Inc | +2.2% | NEW | New buy |
| 12 | TARA | Protara Therapeutic Inc | +2.1% | NEW | New buy |
| 13 | NMRA | Neumora Therapeutics Inc | +1.9% | NEW | New buy |
| 14 | SEPN | Septerna Inc | +1.8% | NEW | New buy |
| 15 | ✓ | Proqr Therapeutics N.v. | +1.5% | NEW | New buy |
| 16 | IRWD | Ironwood Pharmaceuticals Inc | +1.1% | NEW | New buy |
| 17 | VTYXUSD | Ventyx Biosciences Inc | +0.8% | +105.22% | Add |
| 18 | ACOG | Alpha Cognition Inc | +0.7% | NEW | New buy |
| 19 | QTTB | Q32 Bio Inc | +0.7% | NEW | New buy |
| 20 | CRGX | Cargo Therapeutics Inc | +0.7% | +172.23% | Add |
| 21 | TELA | Tela Bio Inc | +0.5% | NEW | New buy |
| 22 | ALEC | Alector Inc | +0.3% | NEW | New buy |
| 23 | OVID | Ovid Therapeutics Inc | +0.3% | NEW | New buy |
| 24 | CCCC | C4 Therapeutics Inc | +0.2% | NEW | New buy |
| 25 | ANNX | Annexon Inc | +0.1% | +65.16% | Add |
| 26 | MESO | Mesoblast Ltd- Spon Adr | +0.1% | NEW | New buy |
| 27 | SVRA | Savara Inc | — | NEW | New buy |
| 28 | ✓ | — | EXIT | Sold out | |
| 29 | ✓ | Modular Med Inc | 0% | +108.65% | Add |
| 30 | 430 | Terns Pharmaceuticals Inc | 0% | — | Unchanged |
| 31 | RCKTW | Rocket Pharmaceuticals In-27 | 0% | — | Unchanged |
| 32 | HUMAW | Humacyte Inc-cw27 | 0% | — | Unchanged |
| 33 | APRE | Aprea Therapeutics Inc | 0% | — | Unchanged |
| 34 | NXTCEUR | Nextcure Inc | 0% | — | Unchanged |
| 35 | ✓ | Nyxoah S A | -0.1% | — | Unchanged |
| 36 | BOLD | Boundless Bio Inc | -0.1% | — | Unchanged |
| 37 | NUVB | Nuvation Bio Inc | -0.1% | — | Unchanged |
| 38 | AVTX | Avalo Therapeutics Inc | -0.1% | — | Unchanged |
| 39 | VSTM | Verastem Inc | -0.2% | EXIT | Sold out |
| 40 | ✓ | Rapt Therapeutics Inc | -0.3% | EXIT | Sold out |
| 41 | ZBH | Zimmer Biomet Holdings Inc | -0.3% | +37.09% | Add |
| 42 | FHTX | Foghorn Therapeutics Inc | -0.3% | — | Unchanged |
| 43 | AORT | Artivion Inc | -0.3% | — | Unchanged |
| 44 | ASNSUSD | X4 Pharmaceuticals Inc | -0.4% | EXIT | Sold out |
| 45 | PMVP | Pmv Pharmaceuticals Inc | -0.4% | +11.14% | Add |
| 46 | ENTA | Enanta Pharmaceuticals Inc | -0.4% | — | Unchanged |
| 47 | TFX | Teleflex Inc | -0.5% | +70.02% | Add |
| 48 | CNTX | Context Therapeutics Inc | -0.6% | — | Unchanged |
| 49 | IDYA | Ideaya Biosciences Inc | -0.7% | — | Unchanged |
| 50 | CATBUSD | Astria Therapeutics Inc | -0.9% | — | Unchanged |
According to official SEC Form 13F filings, Sio Capital Management, LLC reported a total U.S. public equity portfolio value of $604.3M across 51 disclosed positions in Q4 2024.
Expert Analysis & Guides for Tracking Wall Street Smart Money Movements
Learn how SEC Form 13F filings work, the $100M threshold, 45-day reporting lag, and how to track top hedge fund holdings.
In terms of portfolio concentration, the top 5 core holdings (including ICLR, MMS, CI) accounted for 23.4% of total reported equity market value during Q4 2024.
Top New Position Initiated
ICLR
市值: $41.0M
Top Position Liquidated / Trimmed
ISRG
前期市值: $29.0M
During Q4 2024, Sio Capital Management, LLC's top holdings by market value included ICLR (11.5%)、MMS (8.0%)、CI (7.6%). The largest single position, ICLR, represented 11.5% of total portfolio value.
In Q4 2024, Sio Capital Management, LLC made 46 total portfolio adjustments, initiating 22 new buys, adding to 9 positions, trimming 5 holdings, and fully liquidating 10 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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