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CIK: 0001482416
Total reported value
$604.3M
$604.3M
76 檔
30.7%
The Q1 2026 SEC filing reveals that Sio Capital Management, LLC held a total portfolio value of $604.3M, covering 76 public equity positions.
In Q1 2026, Sio Capital Management, LLC displayed an active expansion posture, initiating 23 new positions and adding to 24 existing holdings, outstripping position reductions.
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | MMS | Maximus Inc | Stock-Industrials | 7.07% | -0.71% | +53.67% | |
| 2 | WAY | Waystar Holding CORP | Stock-Other | 5.68% | -2.53% | +167.59% | |
| 3 | ICLR | ICON Public Limited Company | Stock-Healthcare | 4.86% | -2.32% | +140.84% | |
| 4 | COR | Cencora Inc | Stock-Healthcare | 4.55% | +3.58% | +534.55% | |
| 5 | DNTH | Dianthus Therapeutics Inc | Stock-Other | 4.45% | -3.49% | -22.01% | |
| 6 | AVR | Anteris Technologies Global | Stock-Other | 4.28% | +4.76% | +187.15% | |
| 7 | CORT | Corcept Therapeutics Inc | Stock-Healthcare | 3.90% | -3.90% | EXIT | |
| 8 | LIVN | LivaNova PLC | Stock-Other | 3.84% | -3.84% | EXIT | |
| 9 | TYRA | Tyra Biosciences Inc | Stock-Other | 3.33% | +0.35% | +15.10% | |
| 10 | CELC | Celcuity Inc | Stock-Other | 3.17% | -1.27% | -59.37% | |
| 11 | GSK | Gsk Plc-spon Adr | Stock-Healthcare | 3.05% | +0.74% | — | |
| 12 | ANIP | Ani Pharmaceuticals Inc | Stock-Other | 2.93% | -1.60% | +204.27% | |
| 13 | ABT | Abbott Laboratories | Stock-Healthcare | 2.75% | -0.82% | — | |
| 14 | EMBC | Embecta CORP | Stock-Healthcare | 2.34% | -2.34% | EXIT | |
| 15 | ABVX | Abivax Sa-adr | Stock-Other | 2.17% | -2.17% | EXIT | |
| 16 | VIR | Vir Biotechnology Inc | Stock-Other | 1.93% | -0.12% | +213.29% | |
| 17 | HAE | Haemonetics Corp/mass | Stock-Other | 1.78% | -1.78% | EXIT | |
| 18 | SION | Sionna Therapeutics Inc | Stock-Other | 1.69% | -0.76% | — | |
| 19 | SNY | Sanofi-adr | Stock-Healthcare | 1.66% | +0.91% | -75.33% | |
| 20 | RAPP | Rapport Therapeutics Inc | Stock-Other | 1.65% | +0.47% | +97.99% | |
| 21 | TFX | Teleflex Inc | Stock-Healthcare | 1.63% | -1.63% | EXIT | |
| 22 | BMRN | Biomarin Pharmaceutical Inc | Stock-Healthcare | 1.57% | -1.57% | EXIT | |
| 23 | CCRN | Cross Country Healthcare Inc | Stock-Other | 1.48% | +0.92% | +2.77% | |
| 24 | TARA | Protara Therapeutic Inc | Stock-Other | 1.47% | -0.26% | +14.83% | |
| 25 | GPCR | Structure Therapeutics Inc | Stock-Other | 1.45% | -1.45% | EXIT | |
| 26 | BHVN | Biohaven Ltd. | Stock-Other | 1.41% | -1.41% | EXIT | |
| 27 | MNPR | Monopar Therapeutics Inc | Stock-Other | 1.36% | -1.36% | EXIT | |
| 28 | EYPT | Eyepoint Inc | Stock-Other | 1.33% | +0.14% | — | |
| 29 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 1.30% | -1.30% | EXIT | |
| 30 | EWTX | Edgewise Therapeutics Inc | Stock-Other | 1.22% | -1.22% | EXIT | |
| 31 | CMPS | Compass Pathways PLC | Stock-Other | 1.19% | -1.19% | EXIT | |
| 32 | OCUL | Ocular Therapeutix Inc | Stock-Other | 1.18% | -0.30% | — | |
| 33 | AQST | Aquestive Therapeutics Inc | Stock-Other | 1.14% | -0.12% | +93.63% | |
| 34 | RLMD | Relmada Therapeutics Inc | Stock-Other | 0.96% | +0.19% | — | |
| 35 | ORKA | Oruka Therapeutics Inc | Stock-Other | 0.93% | +1.86% | +12.16% | |
| 36 | ZBIO | Zenas Biopharma Inc | Stock-Other | 0.93% | -0.05% | — | |
| 37 | DRUG | Bright Minds Biosciences Inc | Stock-Other | 0.90% | -0.04% | +5.13% | |
| 38 | QDEL | Quidelortho CORP | Stock-Other | 0.85% | -0.85% | EXIT | |
| 39 | ZBH | Zimmer Biomet Holdings Inc | Stock-Healthcare | 0.81% | +1.06% | -83.76% | |
| 40 | REPL | Replimune Group Inc | Stock-Other | 0.79% | -0.79% | EXIT | |
| 41 | OGN | Organon & Co | Stock-Healthcare | 0.74% | -0.74% | EXIT | |
| 42 | OKUR | Onkure Therapeutics Inc-a | Stock-Other | 0.64% | +0.17% | — | |
| 43 | IRON | Disc Medicine Inc | Stock-Other | 0.60% | -0.60% | EXIT | |
| 44 | PMVP | Pmv Pharmaceuticals Inc | Stock-Other | 0.55% | +0.03% | +16.69% | |
| 45 | IMNM | Immunome Inc | Stock-Other | 0.52% | -0.08% | — | |
| 46 | IART | Integra Lifesciences Holding | Stock-Other | 0.52% | -0.52% | EXIT | |
| 47 | SVRA | Savara Inc | Stock-Other | 0.48% | +0.15% | — | |
| 48 | CNC | Centene CORP | Stock-Healthcare | 0.47% | -0.47% | EXIT | |
| 49 | ✓ | Proqr Therapeutics N.v. | Stock-Other | 0.45% | -0.45% | EXIT | |
| 50 | SI | Shoulder Innovations Inc | Stock-Other | 0.44% | -0.44% | EXIT |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | COR | Cencora Inc | +3.7% | +534.55% | Add |
| 2 | AVR | Anteris Technologies Global | +2.8% | +187.15% | Add |
| 3 | WAY | Waystar Holding CORP | +2.5% | +167.59% | Add |
| 4 | ANIP | Ani Pharmaceuticals Inc | +1.9% | +204.27% | Add |
| 5 | VIR | Vir Biotechnology Inc | +1.5% | +213.29% | Add |
| 6 | DNTH | Dianthus Therapeutics Inc | +1.4% | -22.01% | Trim |
| 7 | ABVX | Abivax Sa-adr | +1.3% | +214.91% | Add |
| 8 | ICLR | ICON Public Limited Company | +1.2% | +140.84% | Add |
| 9 | TYRA | Tyra Biosciences Inc | +1.2% | +15.10% | Add |
| 10 | RAPP | Rapport Therapeutics Inc | +0.8% | +97.99% | Add |
| 11 | LIVN | LivaNova PLC | +0.7% | +30.78% | Add |
| 12 | HAE | Haemonetics Corp/mass | +0.6% | +138.23% | Add |
| 13 | CRNX | Crinetics Pharmaceuticals In | +0.4% | +100.16% | Add |
| 14 | ORKA | Oruka Therapeutics Inc | +0.4% | +12.16% | Add |
| 15 | EWTX | Edgewise Therapeutics Inc | +0.3% | +13.27% | Add |
| 16 | MMS | Maximus Inc | +0.3% | +53.67% | Add |
| 17 | AQST | Aquestive Therapeutics Inc | +0.1% | +93.63% | Add |
| 18 | CCRN | Cross Country Healthcare Inc | +0.1% | +2.77% | Add |
| 19 | TARA | Protara Therapeutic Inc | 0% | +14.83% | Add |
| 20 | PMVP | Pmv Pharmaceuticals Inc | 0% | +16.69% | Add |
| 21 | OVID | Ovid Therapeutics Inc | 0% | -12.27% | Trim |
| 22 | CNTX | Context Therapeutics Inc | 0% | -31.58% | Trim |
| 23 | IBIO | Ibio Inc | 0% | +22.20% | Add |
| 24 | 430 | Terns Pharmaceuticals Inc | 0% | — | Unchanged |
| 25 | SENS | Senseonics Holdings Inc | 0% | — | Unchanged |
| 26 | ADGM | Adagio Medical Holdings Inc | — | — | Unchanged |
| 27 | BOLD | Boundless Bio Inc | — | — | Unchanged |
| 28 | HUMAW | Humacyte Inc-cw27 | — | — | Unchanged |
| 29 | RCKTW | Rocket Pharmaceuticals In-27 | — | — | Unchanged |
| 30 | KYMR | Kymera Therapeutics Inc | 0% | — | Unchanged |
| 31 | ✓ | Nyxoah S A | 0% | — | Unchanged |
| 32 | FHTX | Foghorn Therapeutics Inc | 0% | — | Unchanged |
| 33 | ENTA | Enanta Pharmaceuticals Inc | 0% | — | Unchanged |
| 34 | TFX | Teleflex Inc | 0% | +9.12% | Add |
| 35 | TELA | Tela Bio Inc | -0.1% | — | Unchanged |
| 36 | SI | Shoulder Innovations Inc | -0.1% | -7.60% | Trim |
| 37 | ✓ | -0.1% | -56.44% | Trim | |
| 38 | BBOT | Bridgebio Oncology Therapeut | -0.1% | — | Unchanged |
| 39 | SVRA | Savara Inc | -0.1% | — | Unchanged |
| 40 | DRUG | Bright Minds Biosciences Inc | -0.1% | +5.13% | Add |
| 41 | IRON | Disc Medicine Inc | -0.1% | +13.23% | Add |
| 42 | ALGS | Aligos Therapeutics Inc | -0.1% | -2.59% | Trim |
| 43 | HYPR | Hyperfine Inc | -0.2% | -50.00% | Trim |
| 44 | ✓ | Proqr Therapeutics N.v. | -0.2% | -9.68% | Trim |
| 45 | ELTX | Elicio Therapeutics Inc | -0.4% | -96.06% | Trim |
| 46 | BMRN | Biomarin Pharmaceutical Inc | -0.6% | -16.53% | Trim |
| 47 | GPCR | Structure Therapeutics Inc | -0.8% | +3.77% | Add |
| 48 | BHVN | Biohaven Ltd. | -0.8% | -6.49% | Trim |
| 49 | CNC | Centene CORP | -1.3% | -63.55% | Trim |
| 50 | OGN | Organon & Co | -3.1% | -74.69% | Trim |
According to official SEC Form 13F filings, Sio Capital Management, LLC reported a total U.S. public equity portfolio value of $604.3M across 76 disclosed positions in Q1 2026.
Expert Analysis & Guides for Tracking Wall Street Smart Money Movements
Learn how SEC Form 13F filings work, the $100M threshold, 45-day reporting lag, and how to track top hedge fund holdings.
In terms of portfolio concentration, the top 5 core holdings (including MMS, WAY, ICLR) accounted for 30.7% of total reported equity market value during Q1 2026.
Top New Position Initiated
CORT
市值: $27.2M
Top Position Liquidated / Trimmed
CI
前期市值: $47.4M
During Q1 2026, Sio Capital Management, LLC's top holdings by market value included MMS (7.1%)、WAY (5.7%)、ICLR (4.9%). The largest single position, MMS, represented 7.1% of total portfolio value.
In Q1 2026, Sio Capital Management, LLC made 78 total portfolio adjustments, initiating 23 new buys, adding to 24 positions, trimming 16 holdings, and fully liquidating 15 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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