CIK: 0001577524
Total reported value
$177.9M
Reporting period: 2026-06-30 · Number of holdings: 10
Sarissa Capital Management LP disclosed 10 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $177.9M and a quarterly turnover rate of 20.8%.
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Sarissa Capital Management LP's disclosed holdings carry a Herfindahl concentration index of 0.166 — mathematically equivalent to about 6 equally-sized positions, close to its 10 actual disclosed holdings. Value is spread relatively evenly across the portfolio rather than concentrated in a handful of names.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.85), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 2.9 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 34% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
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Trim INVA
-11.3% -$6.7M
Add LNTH
0.0% $5.9M
Add BHVN
+3.4% $3.9M
Add CYTK
0.0% $4.4M
Add NBIX
0.0% $4.3M
Add IRWD
0.0% $6.4M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | INVA | Innoviva Inc | Stock-Other | 24.14% | -7.36% | -11.28% | |
| 2 | IRWD | Ironwood Pharmaceuticals Inc | Stock-Other | 21.75% | +1.29% | — | |
| 3 | AMRN | Amarin CORP PLC -adr | Stock-Other | 15.00% | -0.35% | — | |
| 4 | NBIX | Neurocrine Biosciences Inc | Stock-Healthcare | 11.04% | +1.30% | — | |
| 5 | CYTK | Cytokinetics Inc | Stock-Healthcare | 10.95% | +1.39% | — | |
| 6 | LNTH | Lantheus Holdings Inc | Stock-Healthcare | 10.41% | +2.38% | — | |
| 7 | BHVN | Biohaven Ltd. | Stock-Other | 4.87% | +1.85% | +3.40% | |
| 8 | REGN | Regeneron Pharmaceuticals | Stock-Healthcare | 1.47% | -0.58% | — | |
| 9 | VOR | Vor Biopharma Inc | Stock-Other | 0.26% | -0.03% | — | |
| 10 | BIIB | Biogen Inc | Stock-Healthcare | 0.12% | +0.12% | NEW |
Performance for Q3 2026
+3.3%
Performance Last 4 Quarters
+34.7%
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 10 | $177.9M | 21 | ||
| 2026 Q1 | 9 | $157.6M | 36 | ||
| 2025 Q4 | 9 | $222.9M | 29 | ||
| 2025 Q3 | 8 | $180.4M | 33 | ||
| 2025 Q2 | 7 | $154.4M | 0 | ||
| 2025 Q1 | 7 | $154.7M | 100 | ||
| 2024 Q4 | 8 | $322.9M | 0 | ||
| 2024 Q3 | 10 | $402.3M | 0 | ||
| 2024 Q2 | 10 | $592.4M | 0 | ||
| 2024 Q1 | 10 | $571.6M | 0 | ||
| 2023 Q4 | 9 | $648.9M | 0 | ||
| 2023 Q3 | 11 | $742.4M | 0 | ||
| 2023 Q2 | 11 | $1.0B | 0 | ||
| 2023 Q1 | 11 | $781.9M | 0 | ||
| 2022 Q4 | 11 | $840.2M | 0 | ||
| 2022 Q3 | 11 | $884.8M | 0 | ||
| 2022 Q2 | 11 | $993.5M | 0 | ||
| 2022 Q1 | 11 | $1.1B | 0 | ||
| 2021 Q4 | 11 | $1.2B | 0 | ||
| 2021 Q3 | 10 | $1.3B | 0 | ||
| 2021 Q2 | 14 | $1.3B | 25 | ||
| 2021 Q1 | 14 | $1.0B | 47 | ||
| 2020 Q4 | 12 | $979.8M | 31 | ||
| 2020 Q3 | 11 | $849.4M | 19 | ||
| 2020 Q2 | 12 | $898.9M | 44 | ||
| 2020 Q1 | 12 | $783.8M | 55 | ||
| 2019 Q4 | 13 | $1.2B | 61 | ||
| 2019 Q3 | 12 | $797.9M | 16 | ||
| 2019 Q2 | 13 | $802.2M | 30 | ||
| 2019 Q1 | 11 | $664.3M | 45 | ||
| 2018 Q4 | 10 | $451.2M | 25 | ||
| 2018 Q3 | 9 | $453.3M | 28 | ||
| 2018 Q2 | 10 | $498.8M | 15 | ||
| 2018 Q1 | 11 | $432.1M | 54 | ||
| 2017 Q4 | 11 | $390.7M | 67 | ||
| 2017 Q3 | 9 | $324.0M | 13 | ||
| 2017 Q2 | 8 | $299.6M | 48 | ||
| 2017 Q1 | 11 | $253.1M | 71 | ||
| 2016 Q4 | 11 | $363.1M | 34 | ||
| 2016 Q3 | 14 | $434.2M | 51 | ||
| 2016 Q2 | 15 | $352.3M | 49 | ||
| 2016 Q1 | 16 | $453.8M | 22 | ||
| 2015 Q4 | 17 | $514.4M | 44 | ||
| 2015 Q3 | 18 | $404.9M | 36 | ||
| 2015 Q2 | 16 | $434.6M | 18 | ||
| 2015 Q1 | 17 | $474.1M | 69 | ||
| 2014 Q4 | 16 | $282.5M | 39 | ||
| 2014 Q3 | 14 | $258.9M | 42 | ||
| 2014 Q2 | 15 | $294.1M | 28 | ||
| 2014 Q1 | 15 | $290.4M | 43 | ||
| 2013 Q4 | 12 | $267.0M | 0 |
Sarissa Capital Management LP's most significant position changes for 2026-06-30: New buy: Biogen Inc (BIIB); Trim: Innoviva Inc (INVA) — shares -11.28%; Add: Biohaven Ltd. (BHVN) — shares +3.40%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | LNTH | Lantheus Holdings Inc | +2.4% | — | Unchanged |
| 2 | BHVN | Biohaven Ltd. | +1.9% | +3.40% | Add |
| 3 | CYTK | Cytokinetics Inc | +1.4% | — | Unchanged |
| 4 | NBIX | Neurocrine Biosciences Inc | +1.3% | — | Unchanged |
| 5 | IRWD | Ironwood Pharmaceuticals Inc | +1.3% | — | Unchanged |
| 6 | BIIB | Biogen Inc | +0.1% | NEW | New buy |
| 7 | VOR | Vor Biopharma Inc | 0% | — | Unchanged |
| 8 | AMRN | Amarin CORP PLC -adr | -0.4% | — | Unchanged |
| 9 | REGN | Regeneron Pharmaceuticals | -0.6% | — | Unchanged |
| 10 | INVA | Innoviva Inc | -7.4% | -11.28% | Trim |
Sarissa Capital Management LP returned an annualized 5.1% over the trailing 36 months — outperforming the S&P 500 by 0.0 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.38 (less volatile than the market) and a 36% quarterly batting average against the index.
Its portfolio is concentrated and moderately active, with 100.0% of the portfolio concentrated in Health Care.
Its concentration score has fallen from 94 to 66 over the past 4 quarters — a shift toward broader diversification.
It has added to its LNTH position over the past two quarters (+$6.4M, now $18.5M), while trimming INVA over the same stretch (-$13.4M, still holding $42.9M).
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