CIK: 0001425738
Total reported value
$1.5B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SRRK | Scholar Rock Holding CORP | Stock-Other | 13.37% | +12.57% | -3.33% | |
| 2 | KRYS | Krystal Biotech INC | Stock-Healthcare | 12.57% | -0.78% | -2.06% | |
| 3 | AM6 | Amicus Therapeutics INC | Stock-Other | 7.35% | — | +35.14% | |
| 4 | ZYME | Zymeworks INC | Stock-Other | 5.39% | -0.13% | -1.06% | |
| 5 | NRIX | Nurix Therapeutics INC | Stock-Other | 4.55% | -3.37% | -3.36% | |
| 6 | REPL | Replimune Group INC | Stock-Other | 4.51% | -0.79% | EXIT | |
| 7 | LIVN | LivaNova PLC | Stock-Other | 3.77% | -0.07% | -2.82% | |
| 8 | AKRO | Akero Therapeutics INC | Stock-Other | 3.59% | — | -23.96% | |
| 9 | IMNM | Immunome INC | Stock-Other | 3.41% | -1.00% | +11.04% | |
| 10 | RGNX | Regenxbio INC | Stock-Other | 3.24% | -2.21% | — | |
| 11 | BEAM | Beam Therapeutics INC | Stock-Other | 2.97% | -0.67% | +5.35% | |
| 12 | STOK | Stoke Therapeutics INC | Stock-Other | 2.82% | -0.45% | -2.34% | |
| 13 | KYMR | Kymera Therapeutics INC | Stock-Other | 2.54% | — | -10.63% | |
| 14 | ✓ | Adc Therapeutics SA | Stock-Other | 2.09% | -0.23% | — | |
| 15 | BHVN | Biohaven Ltd. | Stock-Other | 1.97% | — | -4.10% | |
| 16 | ABSI | Absci CORP | Stock-Other | 1.96% | -0.48% | — | |
| 17 | BSX | Boston Scientific CORP | Stock-Healthcare | 1.84% | — | -38.19% | |
| 18 | COGT | Cogent Biosciences INC | Stock-Other | 1.82% | -2.01% | -9.53% | |
| 19 | NGNE | Neurogene INC | Stock-Other | 1.45% | -0.26% | -0.89% | |
| 20 | ETNBGBP | 89bio INC | Stock-Other | 1.30% | — | -12.95% | |
| 21 | ✓ | Establishment Labs Hldgs INC | Stock-Other | 1.29% | -0.21% | +4.75% | |
| 22 | ANNX | Annexon INC | Stock-Other | 1.15% | +1.62% | — | |
| 23 | CLDX | Celldex Therapeutics INC | Stock-Other | 1.01% | -0.02% | -4.16% | |
| 24 | FATE | Fate Therapeutics INC | Stock-Other | 0.96% | +0.09% | — | |
| 25 | IDYA | Ideaya Biosciences INC | Stock-Other | 0.83% | -0.74% | -13.68% | |
| 26 | IMVT | Immunovant INC | Stock-Other | 0.79% | — | -14.24% | |
| 27 | CBLL | Ceribell INC | Stock-Other | 0.79% | -0.23% | — | |
| 28 | ✓ | Rapt Therapeutics INC | Stock-Other | 0.75% | — | — | |
| 29 | SLDB | Solid Biosciences INC | Stock-Other | 0.71% | +0.19% | +228.19% | |
| 30 | PODD | Insulet CORP | Stock-Healthcare | 0.67% | — | +183.60% | |
| 31 | BNTX | Biontech Se-adr | Stock-Other | 0.63% | — | -12.46% | |
| 32 | SLN | Silence Therapeutics Plc-adr | Stock-Other | 0.59% | -0.21% | -7.68% | |
| 33 | PEN | Penumbra INC | Stock-Healthcare | 0.58% | — | -11.27% | |
| 34 | IRTC | Irhythm Holdings INC | Stock-Healthcare | 0.56% | — | — | |
| 35 | KROS | Keros Therapeutics INC | Stock-Other | 0.53% | — | — | |
| 36 | ✓ | Verve Therapeutics INC | Stock-Other | 0.52% | — | -8.42% | |
| 37 | NUVB | Nuvation Bio INC | Stock-Other | 0.50% | -1.19% | — | |
| 38 | STTK | Shattuck Labs INC | Stock-Other | 0.50% | +0.87% | — | |
| 39 | MASI* | Masimo CORP | Stock-Other | 0.41% | — | — | |
| 40 | PRME | Prime Medicine INC | Stock-Other | 0.39% | +0.37% | NEW | |
| 41 | ORKA | Oruka Therapeutics INC | Stock-Other | 0.38% | — | -6.01% | |
| 42 | 1K0 | Igm Biosciences INC | Stock-Other | 0.32% | — | — | |
| 43 | CYTK | Cytokinetics INC | Stock-Healthcare | 0.31% | — | -11.34% | |
| 44 | FDMT | 4d Molecular Therapeutics In | Stock-Other | 0.30% | — | -16.68% | |
| 45 | PLRX | Pliant Therapeutics INC | Stock-Other | 0.26% | -0.09% | -29.08% | |
| 46 | ✓ | Lava Therapeutics NV | Stock-Other | 0.25% | — | — | |
| 47 | ATRA | Atara Biotherapeutics INC | Stock-Other | 0.25% | -0.45% | — | |
| 48 | XERS | Xeris Biopharma Holdings INC | Stock-Other | 0.23% | — | — | |
| 49 | ALXO | Alx Oncology Holdings INC | Stock-Other | 0.21% | +0.79% | -1.32% | |
| 50 | RPTX | Repare Therapeutics INC | Stock-Other | 0.18% | -0.30% | EXIT |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | SRRK | Scholar Rock Holding CORP | +12.4% | -3.33% | Add |
| 2 | AM6 | Amicus Therapeutics INC | +4.4% | +35.14% | Trim |
| 3 | NRIX | Nurix Therapeutics INC | +3.3% | -3.36% | Add |
| 4 | LIVN | LivaNova PLC | +2.4% | -2.82% | Trim |
| 5 | REPL | Replimune Group INC | +2.1% | -0.14% | Add |
| 6 | RGNX | Regenxbio INC | +2% | — | Add |
| 7 | STOK | Stoke Therapeutics INC | +1.6% | -2.34% | Add |
| 8 | KYMR | Kymera Therapeutics INC | +0.7% | -10.63% | Trim |
| 9 | ANNX | Annexon INC | 0% | — | Add |
| 10 | NUVB | Nuvation Bio INC | -0.1% | — | Trim |
| 11 | CLDX | Celldex Therapeutics INC | -0.5% | -4.16% | Trim |
| 12 | ALXO | Alx Oncology Holdings INC | -0.5% | -1.32% | Add |
| 13 | ✓ | Adc Therapeutics SA | -0.6% | — | Add |
| 14 | BEAM | Beam Therapeutics INC | -0.9% | +5.35% | Trim |
| 15 | RPTX | Repare Therapeutics INC | -1% | -1.65% | Trim |
| 16 | PLRX | Pliant Therapeutics INC | -1.1% | -29.08% | Trim |
| 17 | ✓ | Verve Therapeutics INC | -1.2% | -8.42% | Trim |
| 18 | STTK | Shattuck Labs INC | -1.9% | — | Trim |
| 19 | ALLKGUSD | Allakos INC | -2.8% | -71.59% | Trim |
| 20 | 1K0 | Igm Biosciences INC | -3.9% | — | Trim |
| 21 | FATE | Fate Therapeutics INC | -15.7% | — | Trim |
| 22 | ARGX | Argenx Se - Adr | — | EXIT | Sold out |
| 23 | NVTA1EUR | Invitae CORP | — | EXIT | Sold out |
| 24 | DCPHEUR | Deciphera Pharmaceuticals In | — | EXIT | Sold out |
| 25 | JAZZ | Jazz Pharmaceuticals plc | — | EXIT | Sold out |
| 26 | MYOSUSD | Medavail Holdings INC | — | EXIT | Sold out |
| 27 | OSH3USD | Oak Street Health INC | — | EXIT | Sold out |
| 28 | SGENUSD | Seagen INC | — | EXIT | Sold out |
| 29 | SKIN | Skinhealth Systems INC | — | EXIT | Sold out |
| 30 | ATRAGBX | Atara Biotherapeutics INC | — | EXIT | Sold out |
| 31 | NVROEUR | Nevro CORP | — | EXIT | Sold out |
| 32 | DXCM | Dexcom INC | — | EXIT | Sold out |
| 33 | EPZMEUR | Epizyme INC | — | EXIT | Sold out |
| 34 | PRTA | Prothena Corporation plc | — | EXIT | Sold out |
| 35 | ZYUSD | Zymergen INC | — | EXIT | Sold out |
| 36 | IMGNEUR | Immunogen INC | — | EXIT | Sold out |
| 37 | ZYME | Zymeworks INC | — | NEW | New buy |
| 38 | ✓ | 1life Healthcare INC | — | EXIT | Sold out |
| 39 | NGMUSD | Ngm Biopharmaceuticals INC | — | EXIT | Sold out |
| 40 | TCRRUSD | Tcr2 Therapeutics INC | — | EXIT | Sold out |
| 41 | GMAB | Genmab A/s -sp Adr | — | EXIT | Sold out |
| 42 | SLQT | Selectquote INC | — | EXIT | Sold out |
| 43 | ICUI | Icu Medical INC | — | EXIT | Sold out |
| 44 | ELV | Elevance Health INC | — | EXIT | Sold out |
| 45 | CRL | Charles River Laboratories | — | EXIT | Sold out |
| 46 | CI | THE Cigna Group | — | EXIT | Sold out |
| 47 | UNH | Unitedhealth Group INC | — | EXIT | Sold out |
| 48 | ✓ | Neoleukin Therapeutics INC | — | EXIT | Sold out |
| 49 | IMNM | Immunome INC | — | NEW | New buy |
| 50 | LFST | Lifestance Health Group INC | — | EXIT | Sold out |