CIK: 0002106181
Total reported value
$174.0M
Reporting period: 2026-06-30 · Number of holdings: 26
Kalehua Capital Management LLC disclosed 26 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $174.0M and a quarterly turnover rate of 52.4%.
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Sector classification currently covers about 0% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
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Sold out RLAY
Sold out ORKA
New buy KPTI
Add MANE
0.0% $8.7M
New buy IFRX
Add CMPS
0.0% $7.1M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | BOXX | Alpha Architect 1-3 Mnth Box | ETF-Other | 15.22% | -2.74% | +3.62% | |
| 2 | MANE | Veradermics Inc | Stock-Other | 10.30% | +3.79% | — | |
| 3 | XFOR | X4 Pharmaceuticals Inc | Stock-Other | 9.99% | -0.89% | — | |
| 4 | CMPS | Compass Pathways PLC | Stock-Other | 6.67% | +3.46% | — | |
| 5 | SRZN | Surrozen Inc | Stock-Other | 5.75% | -2.19% | — | |
| 6 | ACRS | Aclaris Therapeutics Inc | Stock-Other | 5.57% | +0.71% | — | |
| 7 | SION | Sionna Therapeutics Inc | Stock-Other | 4.98% | -0.61% | — | |
| 8 | IKT | Inhibikase Therapeutics Inc | Stock-Other | 4.46% | -0.08% | — | |
| 9 | PHVS | Pharvaris N.V. | Stock-Other | 3.95% | -0.02% | — | |
| 10 | KPTI | Karyopharm Therapeutics Inc | Stock-Other | 3.85% | +3.85% | NEW | |
| 11 | SEPN | Septerna Inc | Stock-Other | 3.75% | +0.44% | — | |
| 12 | IFRX | InflaRx N.V. | Stock-Other | 3.73% | +3.73% | NEW | |
| 13 | CYCN | Cyclerion Therapeutics Inc | Stock-Other | 3.22% | +3.22% | NEW | |
| 14 | KRRO | Korro Bio Inc | Stock-Other | 3.07% | +2.19% | +270.32% | |
| 15 | QURE | uniQure N.V. | Stock-Other | 2.10% | -1.27% | -72.72% | |
| 16 | LONA | Leonabio Inc | Stock-Other | 2.08% | -0.78% | — | |
| 17 | DMRA | Damora Therapeutics Inc | Stock-Other | 2.08% | -0.47% | — | |
| 18 | MLTX | Moonlake Immunotherapeutics | Stock-Other | 1.97% | -0.35% | — | |
| 19 | ANL | Adlai Nortye Ltd-adr | Stock-Other | 1.50% | +1.50% | NEW | |
| 20 | TYRA | Tyra Biosciences Inc | Stock-Other | 1.37% | -0.65% | — | |
| 21 | NVCT | Nuvectis Pharma Inc | Stock-Other | 1.06% | +1.06% | NEW | |
| 22 | GOSS | Gossamer Bio Inc | Stock-Other | 1.05% | -1.33% | +8.92% | |
| 23 | MIST | Milestone Pharmaceuticals In | Stock-Other | 0.98% | +0.98% | NEW | |
| 24 | ATYR | Atyr Pharma Inc | Stock-Other | 0.61% | +0.61% | NEW | |
| 25 | TIL | Instil Bio Inc | Stock-Other | 0.44% | -0.63% | -45.58% | |
| 26 | TCRX | Tscan Therapeutics Inc | Stock-Other | 0.26% | +0.26% | NEW |
Performance for Q3 2026
+6.8%
Performance Last 4 Quarters
+20.1%
Not enough sector-mapped data yet
Kalehua Capital Management LLC's most significant position changes for 2026-06-30: Sold out: Relay Therapeutics Inc (RLAY); New buy: Karyopharm Therapeutics Inc (KPTI); New buy: InflaRx N.V. (IFRX); Sold out: Oruka Therapeutics Inc (ORKA); New buy: Cyclerion Therapeutics Inc (CYCN).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | KPTI | Karyopharm Therapeutics Inc | +3.9% | NEW | New buy |
| 2 | MANE | Veradermics Inc | +3.8% | — | Unchanged |
| 3 | IFRX | InflaRx N.V. | +3.7% | NEW | New buy |
| 4 | CMPS | Compass Pathways PLC | +3.5% | — | Unchanged |
| 5 | CYCN | Cyclerion Therapeutics Inc | +3.2% | NEW | New buy |
| 6 | KRRO | Korro Bio Inc | +2.2% | +270.32% | Add |
| 7 | ANL | Adlai Nortye Ltd-adr | +1.5% | NEW | New buy |
| 8 | NVCT | Nuvectis Pharma Inc | +1.1% | NEW | New buy |
| 9 | MIST | Milestone Pharmaceuticals In | +1% | NEW | New buy |
| 10 | ACRS | Aclaris Therapeutics Inc | +0.7% | — | Unchanged |
| 11 | ATYR | Atyr Pharma Inc | +0.6% | NEW | New buy |
| 12 | SEPN | Septerna Inc | +0.4% | — | Unchanged |
| 13 | TCRX | Tscan Therapeutics Inc | +0.3% | NEW | New buy |
| 14 | PHVS | Pharvaris N.V. | 0% | — | Unchanged |
| 15 | IKT | Inhibikase Therapeutics Inc | -0.1% | — | Unchanged |
| 16 | LOOP | Loop Industries Inc | -0.3% | EXIT | Sold out |
| 17 | DMAC | Diamedica Therapeutics Inc | -0.3% | EXIT | Sold out |
| 18 | MLTX | Moonlake Immunotherapeutics | -0.4% | — | Unchanged |
| 19 | DMRA | Damora Therapeutics Inc | -0.5% | — | Unchanged |
| 20 | KLRS | Kalaris Therapeutics Inc | -0.6% | EXIT | Sold out |
| 21 | SION | Sionna Therapeutics Inc | -0.6% | — | Unchanged |
| 22 | TIL | Instil Bio Inc | -0.6% | -45.58% | Trim |
| 23 | TYRA | Tyra Biosciences Inc | -0.7% | — | Unchanged |
| 24 | LONA | Leonabio Inc | -0.8% | — | Unchanged |
| 25 | XFOR | X4 Pharmaceuticals Inc | -0.9% | — | Unchanged |
| 26 | TNYA | Tenaya Therapeutics Inc | -1% | EXIT | Sold out |
| 27 | PEPG | Pepgen Inc | -1.3% | EXIT | Sold out |
| 28 | QURE | uniQure N.V. | -1.3% | -72.72% | Trim |
| 29 | GOSS | Gossamer Bio Inc | -1.3% | +8.92% | Add |
| 30 | SRZN | Surrozen Inc | -2.2% | — | Unchanged |
| 31 | BOXX | Alpha Architect 1-3 Mnth Box | -2.7% | +3.62% | Add |
| 32 | ORKA | Oruka Therapeutics Inc | -4.1% | EXIT | Sold out |
| 33 | RLAY | Relay Therapeutics Inc | -6.4% | EXIT | Sold out |
Kalehua Capital Management LLC returned an annualized 44.2% over the trailing 6 months — outperforming the S&P 500 by 37.2 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.08 (less volatile than the market) and a 33% quarterly batting average against the index.
Its portfolio is broadly diversified and moderately active.
Its turnover score has risen from 0 to 52 over the past 2 quarters — a shift toward more active trading.
It has added to its IKT position for two straight quarters, increasing it by $4.2M to reach $7.8M.
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