AB
Ally Bridge Group's 13F Portfolio ($113.1M, Q2 2026)
Ally Bridge GroupCIK: 0001822947
High-turnover traderSector-focusedMomentum follower
Total reported value
$113.1M
Reporting period: 2026-06-30 · Number of holdings: 25
Ally Bridge Group disclosed 25 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $113.1M and a quarterly turnover rate of 123.3%.
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Personality snowflake
- Concentration
- 32.1
- Portfolio Stability
- 100
- Momentum
- 100
- Sector conviction
- 100
- Diversification
- 50
- Sizing Uniformity
- 89.76
Ally Bridge Group's disclosed holdings carry a Herfindahl concentration index of 0.080 — mathematically equivalent to about 12 equally-sized positions, well below its 25 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 1.02), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 4% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govNew buy DFTX
Add ABVX
+270.8% $12.9M
Sold out SLNOEUR
Sold out PRAX
New buy 337185102
Sold out CMPS
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | DFTX | Definium Therapeutics Inc | Stock-Other | 16.64% | +16.64% | NEW | |
| 2 | ABVX | Abivax Sa-adr | Stock-Other | 14.73% | +11.70% | +270.79% | |
| 3 | NERV | Minerva Neurosciences Inc | Stock-Other | 10.68% | +2.62% | +31.43% | |
| 4 | PMN | Promis Neurosciences Inc | Stock-Other | 7.22% | +2.97% | +49.76% | |
| 5 | ✓ | Stock-Other | 5.06% | +5.06% | NEW | ||
| 6 | AXSM | Axsome Therapeutics Inc | Stock-Healthcare | 3.57% | +3.57% | NEW | |
| 7 | ASMB | Assembly Biosciences Inc | Stock-Other | 3.40% | +3.40% | NEW | |
| 8 | WHWK | Whitehawk Therapeutics Inc | Stock-Other | 3.31% | +1.03% | — | |
| 9 | EWTX | Edgewise Therapeutics Inc | Stock-Other | 2.99% | -1.11% | -48.26% | |
| 10 | CLYM | Climb Bio Inc | Stock-Other | 2.87% | +2.87% | NEW | |
| 11 | KURA | Kura Oncology Inc | Stock-Other | 2.81% | +2.81% | NEW | |
| 12 | CTMX | Cytomx Therapeutics Inc | Stock-Other | 2.57% | -0.85% | -13.89% | |
| 13 | AVTX | Avalo Therapeutics Inc | Stock-Other | 2.45% | +2.45% | NEW | |
| 14 | PALI | Palisade Bio Inc | Stock-Other | 2.27% | +2.27% | NEW | |
| 15 | SLDB | Solid Biosciences Inc | Stock-Other | 2.26% | -2.20% | -66.63% | |
| 16 | ANTX | An2 Therapeutics Inc | Stock-Other | 2.25% | +0.80% | — | |
| 17 | URGN | UroGen Pharma Ltd. | Stock-Other | 2.25% | -0.69% | -65.77% | |
| 18 | CATX | Perspective Therapeutics Inc | Stock-Other | 2.24% | -0.88% | -19.71% | |
| 19 | IDYA | Ideaya Biosciences Inc | Stock-Other | 2.22% | +2.22% | NEW | |
| 20 | IVA | Inventiva SA - Adr | Stock-Other | 2.12% | -1.22% | -14.83% | |
| 21 | ALMS | Alumis Inc | Stock-Other | 1.90% | -1.07% | -54.20% | |
| 22 | OVID | Ovid Therapeutics Inc | Stock-Other | 1.49% | -3.56% | -77.84% | |
| 23 | EPRX | Eupraxia Pharmaceuticals Inc | Stock-Other | 1.47% | -2.39% | -61.81% | |
| 24 | IBIO | Ibio Inc | Stock-Other | 0.60% | +0.60% | NEW | |
| 25 | TRAW | Traws Pharma Inc | Stock-Other | 0.59% | +0.59% | NEW |
Portfolio Performance
Performance for Q3 2026
+10.2%
Performance Last 4 Quarters
+58.7%
Based on 89% of reported portfolio value with available pricing
- Stdev
- +45.8%
- Beta
- +1.21
- Alpha
- +7.7%
- Max Drawdown
- -43%
- Annualized Perf
- +23.4%
- Batting Avg vs S&P
- +53.3%
- Sortino
- +1.22
- Stutzer
- +0.2
- Treynor
- +0.26
- Sterling
- +0.66
- Calmar
- +0.54
- Information Ratio
- +0.27
- Tracking Error
- +42.9%
- Stdev Down
- +25.6%
- Winning Months %
- +56.7%
- Losing Months %
- +43.3%
- Best 12 Months
- +91.9%
- Worst 12 Months
- -35.7%
- Efficiency Ratio
- +0.22
- Sharpe
- +0.68
- Stdev Sectors
- 0%
- Skewness
- +0.23
- Kurtosis
- +0.69
- Upside Potential
- +3.05
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 25 | $113.1M | 100 | ||
| 2026 Q1 | 28 | $123.8M | 95 | ||
| 2025 Q4 | 20 | $96.0M | 100 | ||
| 2025 Q3 | 25 | $164.2M | 100 | ||
| 2025 Q2 | 24 | $120.2M | 0 | ||
| 2025 Q1 | 28 | $110.9M | 100 | ||
| 2024 Q4 | 30 | $116.6M | 0 | ||
| 2024 Q3 | 29 | $186.8M | 0 | ||
| 2024 Q2 | 25 | $167.9M | 0 | ||
| 2024 Q1 | 22 | $179.9M | 0 | ||
| 2023 Q4 | 22 | $167.8M | 0 | ||
| 2023 Q3 | 19 | $85.2M | 0 | ||
| 2023 Q2 | 17 | $82.6M | 0 | ||
| 2023 Q1 | 18 | $76.3M | 0 | ||
| 2022 Q4 | 30 | $102.8M | 0 | ||
| 2022 Q3 | 39 | $151.5M | 0 | ||
| 2022 Q2 | 22 | $109.7M | 0 | ||
| 2022 Q1 | 21 | $134.9M | 0 | ||
| 2021 Q4 | 30 | $286.1M | 0 | ||
| 2021 Q3 | 31 | $340.1M | 0 | ||
| 2021 Q2 | 29 | $402.5M | 100 | ||
| 2021 Q1 | 32 | $521.6M | 50 | ||
| 2020 Q4 | 30 | $583.5M | 0 |
Holding changes this quarter
Ally Bridge Group's most significant position changes for 2026-06-30: New buy: Definium Therapeutics Inc (DFTX); Sold out: Soleno Therapeutics Inc (SLNOEUR); Sold out: Praxis Precision Medicines I (PRAX); Sold out: Compass Pathways PLC (CMPS); New buy: .
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | DFTX | Definium Therapeutics Inc | +16.6% | NEW | New buy |
| 2 | ABVX | Abivax Sa-adr | +11.7% | +270.79% | Add |
| 3 | ✓ | +5.1% | NEW | New buy | |
| 4 | AXSM | Axsome Therapeutics Inc | +3.6% | NEW | New buy |
| 5 | ASMB | Assembly Biosciences Inc | +3.4% | NEW | New buy |
| 6 | PMN | Promis Neurosciences Inc | +3% | +49.76% | Add |
| 7 | CLYM | Climb Bio Inc | +2.9% | NEW | New buy |
| 8 | KURA | Kura Oncology Inc | +2.8% | NEW | New buy |
| 9 | NERV | Minerva Neurosciences Inc | +2.6% | +31.43% | Add |
| 10 | AVTX | Avalo Therapeutics Inc | +2.5% | NEW | New buy |
| 11 | PALI | Palisade Bio Inc | +2.3% | NEW | New buy |
| 12 | IDYA | Ideaya Biosciences Inc | +2.2% | NEW | New buy |
| 13 | WHWK | Whitehawk Therapeutics Inc | +1% | — | Unchanged |
| 14 | ANTX | An2 Therapeutics Inc | +0.8% | — | Unchanged |
| 15 | IBIO | Ibio Inc | +0.6% | NEW | New buy |
| 16 | TRAW | Traws Pharma Inc | +0.6% | NEW | New buy |
| 17 | URGN | UroGen Pharma Ltd. | -0.7% | -65.77% | Trim |
| 18 | CTMX | Cytomx Therapeutics Inc | -0.9% | -13.89% | Trim |
| 19 | CATX | Perspective Therapeutics Inc | -0.9% | -19.71% | Trim |
| 20 | ALMS | Alumis Inc | -1.1% | -54.20% | Trim |
| 21 | EWTX | Edgewise Therapeutics Inc | -1.1% | -48.26% | Trim |
| 22 | KPTI | Karyopharm Therapeutics Inc | -1.1% | EXIT | Sold out |
| 23 | RLMD | Relmada Therapeutics Inc | -1.2% | EXIT | Sold out |
| 24 | IVA | Inventiva SA - Adr | -1.2% | -14.83% | Trim |
| 25 | REPL | Replimune Group Inc | -1.5% | EXIT | Sold out |
| 26 | IKT | Inhibikase Therapeutics Inc | -1.8% | EXIT | Sold out |
| 27 | SLDB | Solid Biosciences Inc | -2.2% | -66.63% | Trim |
| 28 | EPRX | Eupraxia Pharmaceuticals Inc | -2.4% | -61.81% | Trim |
| 29 | MAZE | Maze Therapeutics Inc | -2.4% | EXIT | Sold out |
| 30 | CAPR | Capricor Therapeutics Inc | -2.8% | EXIT | Sold out |
| 31 | OVID | Ovid Therapeutics Inc | -3.6% | -77.84% | Trim |
| 32 | QURE | uniQure N.V. | -4% | EXIT | Sold out |
| 33 | CMPX | Compass Therapeutics Inc | -4.3% | EXIT | Sold out |
| 34 | TARS | Tarsus Pharmaceuticals Inc | -4.6% | EXIT | Sold out |
| 35 | CMPS | Compass Pathways PLC | -4.7% | EXIT | Sold out |
| 36 | PRAX | Praxis Precision Medicines I | -8.5% | EXIT | Sold out |
| 37 | SLNOEUR | Soleno Therapeutics Inc | -10.8% | EXIT | Sold out |
Filing History
FAQ
What is Ally Bridge Group and what type of investor is it?
Ally Bridge Group is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $113.1M, spread across 25 disclosed positions.
What are Ally Bridge Group's largest equity positions?
Based on the latest 13F filing, Ally Bridge Group's top holdings by market value are:
1. Definium Therapeutics Inc (DFTX) — $18.8M (16.6%)
2. Abivax Sa-adr (ABVX) — $16.7M (14.7%)
3. Minerva Neurosciences Inc (NERV) — $12.1M (10.7%)
4. Promis Neurosciences Inc (PMN) — $8.2M (7.2%)
5. — $5.7M (5.1%)
What changes did Ally Bridge Group make in its most recent portfolio filing?
In the latest reported quarter, Ally Bridge Group made 35 notable position adjustments: 11 new positions were initiated, 3 existing holdings were added to, 9 positions were partially reduced, and 12 were completely exited. The largest of these moves: New buy: Definium Therapeutics Inc (DFTX); Sold out: Soleno Therapeutics Inc (SLNOEUR); Sold out: Praxis Precision Medicines I (PRAX); Sold out: Compass Pathways PLC (CMPS); New buy:
What sectors does Ally Bridge Group focus on?
Ally Bridge Group is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
* This report is exclusively curated by the AlphaSMO team. AlphaSMO is the web's most authoritative 13F / Inside Trader database, delivering precise insider trading and institutional holdings insights.
Investment Profile
Ally Bridge Group returned an annualized 23.4% over the trailing 30 months — outperforming the S&P 500 by 7.7 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 1.21 (more volatile than the market) and a 53% quarterly batting average against the index.
Its portfolio is broadly diversified and fast-trading, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 100 over the past 4 quarters — a shift toward more active trading.
It has added to its PMN position over the past two quarters (+$6.5M, now $8.2M), while trimming EWTX over the same stretch (-$7.7M, still holding $3.4M).
Peer Institutions
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Total reported value
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Concentration9.4
Portfolio Stability22.8
Sector conviction44.4
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IA
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CIK 0002090165
Total reported value
$113.1M
152 stks
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Concentration6.5
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TI
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CIK 0001112179
Total reported value
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Concentration9.9
Portfolio Stability11.4
Sector conviction60.5
AUM within 0.2% of this institution
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Developer Access
Access Ally Bridge Group's institutional profile programmatically:
REST API
curl https://alphasmo.com/api/v1/institutions/ally-bridge-group-ny-llcCLI
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