Iovance Biotherapeutics Inc (IOVA) — Institutional Holders Breakdown (Q2 2026)

IOVA ranks #2189 out of 37501 tracked stocks by institutional interest — one of the most closely watched names in our coverage.

IOVA is a disclosed holding of Two Sigma (Two Sigma Investments), one of the tracked superinvestors on AlphaSMO — it makes up 0.1% of that fund's own 13F portfolio.

IOVA is a top-conviction position for Mhr Fund Management LLC — at 6.3% of their entire disclosed 13F portfolio, it's one of their largest single bets, not just a passing allocation.

The largest dollar stake in IOVA belongs to California State Teachers Retirement System, but the position matters far more to Mhr Fund Management LLC, who has 6.3% of their own portfolio riding on it — a reminder that the biggest holder by size and the holder with the biggest bet aren't always the same fund.

California State Teachers Retirement System has added to its IOVA position for two straight quarters, increasing it by $396.1M to reach $397.0M today.

Invenomic Capital Management LP has trimmed its IOVA position for two straight quarters, cutting it by $26.5M while still holding $6.2M.

IOVA is down 3% today, but institutions show net buying of $139.9M this quarter — a divergence between today's price move and the underlying institutional flow.

IOVA reported a net loss of $289.5M over the trailing twelve months.

• Not yet profitable — net loss of $289.5M over the trailing twelve months
• Revenue grew 34.5% year over year
• Net income improved year over year, from -$389.9M to -$289.5M
• Operating cash flow was negative, using $302.4M in cash
• Current ratio of 3.20x — enough short-term assets to cover short-term liabilities
• Liabilities run 0.31x equity — within a conventional range