IONS 13F Ownership: 495 Institutions

495 institutions currently hold IONS, ranked below by position value.

Key Holders	Total Value	Avg Weight
WOLVERINE ASSET MANAGEMENT LLC	$5.1M	0.05%
Treasurer of the State of North Carolina	$5.1M	0.02%
Police & Firemen's Retirement System of New Jersey	$5.1M	0.04%
LMR Partners LLP	$5.0M	0.01%
SG Americas Securities, LLC	$4.8M	0.01%
Russell Investments Group, Ltd.	$4.7M	0.01%
Orion Porfolio Solutions, LLC	$4.6M	0.04%
Polymer Capital Management (HK) LTD	$4.6M	0.40%
Rafferty Asset Management, LLC	$4.5M	0.02%
Zurcher Kantonalbank (Zurich Cantonalbank)	$4.5M	0.01%
Jefferies Financial Group Inc.	$4.4M	0.03%
One Capital Management, LLC	$4.4M	0.12%
Future Fund LLC	$4.4M	1.55%
PANAGORA ASSET MANAGEMENT INC	$4.3M	0.02%
DCF Advisers, LLC	$4.2M	1.12%
PEAK6 LLC	$4.2M	0.01%
Quantinno Capital Management LP	$4.2M	0.01%
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.	$4.1M	0.14%
State of New Jersey Common Pension Fund D	$3.9M	0.02%
Creative Planning	$3.9M	0.00%
NICOLA WEALTH MANAGEMENT LTD.	$3.9M	0.47%
ADAGE CAPITAL PARTNERS GP, L.L.C.	$3.8M	0.01%
CAPITAL COUNSEL LLC/NY	$3.7M	0.16%
E Fund Management Co., Ltd.	$3.5M	0.10%
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	$3.5M	0.01%
Ensign Peak Advisors, Inc	$3.5M	0.01%
BAMCO INC /NY/	$3.4M	0.01%
WEST MICHIGAN ADVISORS, LLC	$3.4M	0.74%
GUGGENHEIM CAPITAL LLC	$3.3M	0.03%
Qube Research & Technologies Ltd	$3.2M	0.00%
ARIZONA STATE RETIREMENT SYSTEM	$3.2M	0.02%
Tetragon Partners GP Ltd	$3.1M	0.61%
Stanley-Laman Group, Ltd.	$3.0M	0.36%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.	$2.9M	2.60%
Vanguard Investments Australia, Ltd.	$2.9M	0.01%
INTECH INVESTMENT MANAGEMENT LLC	$2.9M	0.03%
GRANDFIELD & DODD, LLC	$2.8M	0.16%
Point72 Asset Management, L.P.	$2.8M	0.00%
Raiffeisen Bank International AG	$2.7M	0.04%
PRUDENTIAL FINANCIAL INC	$2.6M	0.00%
BLB&B Advisors, LLC	$2.6M	0.11%
VAN ECK ASSOCIATES CORP	$2.6M	0.00%
EXCHANGE TRADED CONCEPTS, LLC	$2.5M	0.02%
KLP KAPITALFORVALTNING AS	$2.5M	0.01%
BLAIR WILLIAM & CO/IL	$2.5M	0.01%
Assenagon Asset Management S.A.	$2.5M	0.00%
Tidal Investments LLC	$2.5M	0.01%
Pathstone Holdings, LLC	$2.5M	0.01%
Swedbank AB	$2.4M	0.00%
LPL Financial LLC	$2.4M	0.00%
KBC Group NV	$2.3M	0.01%
PRELUDE CAPITAL MANAGEMENT, LLC	$2.2M	0.17%
KORNITZER CAPITAL MANAGEMENT INC /KS	$2.2M	0.05%
AQR CAPITAL MANAGEMENT LLC	$2.2M	0.00%
STRS OHIO	$2.2M	0.01%
FRED ALGER MANAGEMENT, LLC	$2.1M	0.01%
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	$2.1M	0.02%
WORLDQUANT MILLENNIUM ADVISORS LLC	$2.1M	0.01%
Entropy Technologies, LP	$2.0M	0.09%
BANK OF MONTREAL /CAN/	$2.0M	0.00%
STEMPOINT CAPITAL LP	$2.0M	0.38%
XPONANCE LLC	$2.0M	0.01%
PROFUND ADVISORS LLC	$2.0M	0.07%
Jain Global LLC	$2.0M	0.01%
FLORIDA FINANCIAL ADVISORS, LLC	$1.9M	0.47%
Qsemble Capital Management, LP	$1.9M	0.15%
JONES FINANCIAL COMPANIES LLLP	$1.9M	0.00%
LAZARD ASSET MANAGEMENT LLC	$1.9M	0.00%
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	$1.8M	0.01%
Man Group plc	$1.8M	0.00%
Amundi	$1.8M	0.00%
NATIXIS ADVISORS, LLC	$1.8M	0.00%
Voleon Capital Management LP	$1.7M	0.04%
CANADA LIFE ASSURANCE Co	$1.7M	0.00%
Informed Momentum Co LLC	$1.5M	0.18%
ALLSTATE CORP	$1.5M	0.02%
READYSTATE ASSET MANAGEMENT LP	$1.5M	0.07%
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	$1.5M	0.10%
Legato Capital Management LLC	$1.5M	0.14%
Calamos Advisors LLC	$1.5M	0.01%
FORA Capital, LLC	$1.5M	0.11%
Nicollet Investment Management, Inc.	$1.5M	0.51%
AlphaCentric Advisors LLC	$1.5M	1.47%
DNB Asset Management AS	$1.4M	0.01%
Dana Investment Advisors, Inc.	$1.4M	0.04%
INCEPTIONR LLC	$1.3M	0.30%
NORTH STAR ASSET MANAGEMENT INC	$1.2M	0.05%
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	$1.2M	0.00%
Caption Management, LLC	$1.2M	0.01%
BROWN ADVISORY INC	$1.1M	0.00%
M&G PLC	$1.1M	0.01%
IQ EQ FUND MANAGEMENT (IRELAND) Ltd	$1.1M	0.08%
Bleakley Financial Group, LLC	$1.1M	0.02%
CANADA PENSION PLAN INVESTMENT BOARD	$1.1M	0.00%
Dynasty Wealth Management, LLC	$1.1M	0.01%
PNC FINANCIAL SERVICES GROUP, INC.	$1.0M	0.00%
Westmount Partners, LLC	$973.2K	0.24%
TRUIST FINANCIAL CORP	$964.6K	0.00%
HIGHLAND CAPITAL MANAGEMENT, LLC	$962.6K	0.05%
Annis Gardner Whiting Capital Advisors, LLC	$961.2K	0.15%
Allianz Asset Management GmbH	$946.2K	0.00%
VELA Investment Management, LLC	$938.6K	0.22%
SBI Okasan Asset Management Co.Ltd.	$913.8K	0.04%
AMALGAMATED BANK	$905.0K	0.01%
OPPENHEIMER ASSET MANAGEMENT INC.	$890.0K	0.01%
Summit Trail Advisors, LLC	$867.2K	0.01%
HORIZON KINETICS ASSET MANAGEMENT LLC	$858.1K	0.01%
Vanguard Personalized Indexing Management, LLC	$857.1K	0.01%
Cetera Investment Advisers	$847.0K	0.00%
Plancorp, LLC	$842.5K	0.02%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	$835.2K	0.00%
Capstone Capital Management Ltd	$832.4K	0.84%
FIFTH THIRD BANCORP	$826.8K	0.00%
&PARTNERS	$819.2K	0.00%
SUVRETTA CAPITAL MANAGEMENT, LLC	$811.0K	0.02%
Virtus Investment Advisers, LLC	$784.3K	0.22%
Federation des caisses Desjardins du Quebec	$751.3K	0.00%
Thrivent Financial for Lutherans	$748.0K	0.00%
ASSETMARK, INC	$718.9K	0.00%
Vident Advisory, LLC	$712.5K	0.01%
MetLife Investment Management, LLC	$692.6K	0.00%
Swiss Life Asset Management Ltd	$689.0K	0.00%
Mirae Asset Global Investments Co., Ltd.	$678.0K	0.00%
Aigen Investment Management, LP	$660.0K	0.17%
OSAIC HOLDINGS, INC.	$654.0K	0.00%
Savant Capital, LLC	$635.3K	0.00%
denkapparat Operations GmbH	$628.1K	0.26%
Utah Retirement Systems	$623.2K	0.01%
SECTORAL ASSET MANAGEMENT INC	$617.2K	0.51%
COMMERCE BANK	$613.1K	0.00%
COMMONWEALTH EQUITY SERVICES, LLC	$587.9K	0.00%
Stratos Wealth Partners, LTD.	$579.3K	0.01%
O'SHAUGHNESSY ASSET MANAGEMENT, LLC	$577.2K	0.00%
Cerity Partners LLC	$570.4K	0.00%
Fiduciary Trust Co	$555.6K	0.01%
ProShare Advisors LLC	$554.9K	0.00%
Maryland State Retirement & Pension System	$554.2K	0.01%
Ground Swell Capital, LLC	$547.0K	1.08%
Meeder Advisory Services, Inc.	$543.6K	0.02%
M&T Bank Corp	$540.5K	0.00%
Callan Family Office, LLC	$531.8K	0.01%
SILVERCREST ASSET MANAGEMENT GROUP LLC	$529.6K	0.00%
PRINCIPAL FINANCIAL GROUP INC	$527.1K	0.00%
PSP Research LLC	$510.6K	0.36%
Significant Wealth Partners LLC	$500.4K	0.62%
Wedmont Private Capital	$492.2K	0.02%
J. Safra Sarasin Holding AG	$482.9K	0.01%
MERCER GLOBAL ADVISORS INC /ADV	$472.8K	0.00%
PRAXIS INVESTMENT MANAGEMENT INC	$468.0K	0.03%
REGIONS FINANCIAL CORP	$459.7K	0.00%