TL
Tri Locum Partners LP 13F Holdings & Recent Stock Buys (Q2 2026)
Tri Locum Partners LPCIK: 0001826434
Sector-focusedMomentum followerQuality / disciplined sizing
Total reported value
$813.2M
Reporting period: 2026-06-30 · Number of holdings: 19
Tri Locum Partners LP disclosed 19 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $813.2M and a quarterly turnover rate of 77.7%.
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Personality snowflake
- Concentration
- 31.37
- Portfolio Stability
- 77.74
- Momentum
- 100
- Sector conviction
- 100
- Diversification
- 38
- Sizing Uniformity
- 92.81
Tri Locum Partners LP's disclosed holdings carry a Herfindahl concentration index of 0.078 — mathematically equivalent to about 13 equally-sized positions, close to its 19 actual disclosed holdings. Value is spread relatively evenly across the portfolio rather than concentrated in a handful of names.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.72), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govSold out TMO
New buy K08588103
Sold out ASND
Trim ISRG
-68.7% -$51.6M
New buy ELVN
Add AXSM
+253.1% $43.2M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | JNJ | Johnson & Johnson | Stock-Healthcare | 13.27% | -0.95% | +2.52% | |
| 2 | VRTX | Vertex Pharmaceuticals Inc | Stock-Healthcare | 12.33% | +4.23% | +56.05% | |
| 3 | LLY | Eli Lilly & Co | Stock-Healthcare | 11.29% | +3.31% | +23.85% | |
| 4 | ✓ | Ascendis Pharma A/s | Stock-Other | 8.49% | +8.49% | NEW | |
| 5 | DXCM | Dexcom Inc | Stock-Healthcare | 6.80% | +0.65% | +17.52% | |
| 6 | AXSM | Axsome Therapeutics Inc | Stock-Healthcare | 6.60% | +5.13% | +253.06% | |
| 7 | JAZZ | Jazz Pharmaceuticals plc | Stock-Healthcare | 6.57% | +2.36% | +39.74% | |
| 8 | ELVN | Enliven Therapeutics Inc | Stock-Other | 5.41% | +5.41% | NEW | |
| 9 | ARGX | Argenx Se - Adr | Stock-Healthcare | 4.75% | +1.51% | +31.49% | |
| 10 | MDGL | Madrigal Pharmaceuticals Inc | Stock-Healthcare | 4.51% | -3.08% | -33.90% | |
| 11 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 3.50% | +3.50% | NEW | |
| 12 | UTHR | United Therapeutics CORP | Stock-Healthcare | 3.13% | -2.73% | -33.17% | |
| 13 | TEVA | Teva Pharmaceutical-sp Adr | Stock-Healthcare | 3.11% | -1.21% | -26.85% | |
| 14 | TARS | Tarsus Pharmaceuticals Inc | Stock-Other | 2.54% | +0.05% | +29.99% | |
| 15 | ISRG | Intuitive Surgical Inc | Stock-Healthcare | 2.35% | -7.56% | -68.69% | |
| 16 | CYTK | Cytokinetics Inc | Stock-Healthcare | 2.03% | +2.03% | NEW | |
| 17 | DNTH | Dianthus Therapeutics Inc | Stock-Other | 1.45% | -0.26% | -17.06% | |
| 18 | BBNX | Beta Bionics Inc | Stock-Other | 0.95% | +0.95% | NEW | |
| 19 | DFTX | Definium Therapeutics Inc | Stock-Other | 0.94% | -0.04% | -55.90% |
Portfolio Performance
Performance for Q3 2026
+12%
Performance Last 4 Quarters
+59.5%
- Stdev
- +28.6%
- Beta
- +0.73
- Alpha
- +18.3%
- Max Drawdown
- -21.3%
- Annualized Perf
- +33.3%
- Batting Avg vs S&P
- +52.8%
- Sortino
- +2.25
- Stutzer
- +0.34
- Treynor
- +0.45
- Sterling
- +1.42
- Calmar
- +1.57
- Information Ratio
- +0.48
- Tracking Error
- +27.2%
- Stdev Down
- +14.6%
- Winning Months %
- +58.3%
- Losing Months %
- +41.7%
- Best 12 Months
- +86.7%
- Worst 12 Months
- -7.7%
- Efficiency Ratio
- +0.65
- Sharpe
- +1.15
- Stdev Sectors
- 0%
- Skewness
- +0.54
- Kurtosis
- +4.02
- Upside Potential
- +3.54
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 19 | $813.2M | 78 | ||
| 2026 Q1 | 17 | $712.5M | 81 | ||
| 2025 Q4 | 15 | $770.1M | 100 | ||
| 2025 Q3 | 18 | $435.1M | 100 | ||
| 2025 Q2 | 23 | $329.5M | 0 | ||
| 2025 Q1 | 22 | $194.9M | 100 | ||
| 2024 Q4 | 28 | $482.7M | 0 | ||
| 2024 Q3 | 20 | $417.4M | 0 | ||
| 2024 Q2 | 25 | $395.5M | 0 | ||
| 2024 Q1 | 27 | $288.4M | 0 | ||
| 2023 Q4 | 24 | $218.8M | 0 | ||
| 2023 Q3 | 61 | $312.8M | 0 | ||
| 2023 Q2 | 59 | $269.1M | 0 | ||
| 2023 Q1 | 47 | $328.3M | 0 | ||
| 2022 Q4 | 73 | $247.2M | 0 | ||
| 2022 Q3 | 41 | $364.3M | 0 | ||
| 2022 Q2 | 51 | $244.2M | 0 | ||
| 2022 Q1 | 37 | $256.0M | 0 | ||
| 2021 Q4 | 41 | $254.0M | 0 | ||
| 2021 Q3 | 30 | $251.6M | 0 | ||
| 2021 Q2 | 31 | $305.5M | 100 | ||
| 2021 Q1 | 35 | $403.2M | 100 | ||
| 2020 Q4 | 65 | $275.4M | 0 |
Holding changes this quarter
Tri Locum Partners LP's most significant position changes for 2026-06-30: New buy: Ascendis Pharma A/s; Sold out: Thermo Fisher Scientific Inc (TMO); Sold out: Ascendis Pharma A/S (ASND); New buy: Enliven Therapeutics Inc (ELVN); Sold out: Nuvalent Inc-a (NUVL).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ✓ | Ascendis Pharma A/s | +8.5% | NEW | New buy |
| 2 | ELVN | Enliven Therapeutics Inc | +5.4% | NEW | New buy |
| 3 | AXSM | Axsome Therapeutics Inc | +5.1% | +253.06% | Add |
| 4 | VRTX | Vertex Pharmaceuticals Inc | +4.2% | +56.05% | Add |
| 5 | RVMD | Revolution Medicines Inc | +3.5% | NEW | New buy |
| 6 | LLY | Eli Lilly & Co | +3.3% | +23.85% | Add |
| 7 | JAZZ | Jazz Pharmaceuticals plc | +2.4% | +39.74% | Add |
| 8 | CYTK | Cytokinetics Inc | +2% | NEW | New buy |
| 9 | ARGX | Argenx Se - Adr | +1.5% | +31.49% | Add |
| 10 | BBNX | Beta Bionics Inc | +1% | NEW | New buy |
| 11 | DXCM | Dexcom Inc | +0.7% | +17.52% | Add |
| 12 | TARS | Tarsus Pharmaceuticals Inc | +0.1% | +29.99% | Add |
| 13 | DFTX | Definium Therapeutics Inc | 0% | -55.90% | Trim |
| 14 | DNTH | Dianthus Therapeutics Inc | -0.3% | -17.06% | Trim |
| 15 | JNJ | Johnson & Johnson | -1% | +2.52% | Add |
| 16 | TEVA | Teva Pharmaceutical-sp Adr | -1.2% | -26.85% | Trim |
| 17 | UTHR | United Therapeutics CORP | -2.7% | -33.17% | Trim |
| 18 | MDGL | Madrigal Pharmaceuticals Inc | -3.1% | -33.90% | Trim |
| 19 | NUVL | Nuvalent Inc-a | -4.4% | EXIT | Sold out |
| 20 | ISRG | Intuitive Surgical Inc | -7.6% | -68.69% | Trim |
| 21 | ASND | Ascendis Pharma A/S | -8.2% | EXIT | Sold out |
| 22 | TMO | Thermo Fisher Scientific Inc | -9.1% | EXIT | Sold out |
Filing History
FAQ
What is Tri Locum Partners LP and what type of investor is it?
Tri Locum Partners LP is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $813.2M, spread across 19 disclosed positions.
What are Tri Locum Partners LP's largest equity positions?
Based on the latest 13F filing, Tri Locum Partners LP's top holdings by market value are:
1. Johnson & Johnson (JNJ) — $107.9M (13.3%)
2. Vertex Pharmaceuticals Inc (VRTX) — $100.2M (12.3%)
3. Eli Lilly & Co (LLY) — $91.8M (11.3%)
4. Ascendis Pharma A/s — $69.0M (8.5%)
5. Dexcom Inc (DXCM) — $55.3M (6.8%)
What changes did Tri Locum Partners LP make in its most recent portfolio filing?
In the latest reported quarter, Tri Locum Partners LP made 22 notable position adjustments: 5 new positions were initiated, 8 existing holdings were added to, 6 positions were partially reduced, and 3 were completely exited. The largest of these moves: New buy: Ascendis Pharma A/s; Sold out: Thermo Fisher Scientific Inc (TMO); Sold out: Ascendis Pharma A/S (ASND); New buy: Enliven Therapeutics Inc (ELVN); Sold out: Nuvalent Inc-a (NUVL)
What sectors does Tri Locum Partners LP focus on?
Tri Locum Partners LP is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
Tri Locum Partners LP returned an annualized 33.3% over the trailing 36 months — outperforming the S&P 500 by 18.3 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.73 (less volatile than the market) and a 53% quarterly batting average against the index.
Its portfolio is broadly diversified and fast-trading, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 78 over the past 4 quarters — a shift toward more active trading.
It has added to its DXCM position over the past two quarters (+$27.3M, now $55.3M), while trimming UTHR over the same stretch (-$33.4M, still holding $25.5M).
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Developer Access
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REST API
curl https://alphasmo.com/api/v1/institutions/tri-locum-partners-lpCLI
npx alphasmo institutions get tri-locum-partners-lp