CIK: 0001224962
Total reported value
$5.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | CERE1EUR | Cerevel Therapeutics Holding | Stock-Other | 7.98% | — | -1.55% | |
| 2 | AM6 | Amicus Therapeutics INC | Stock-Other | 5.78% | -1.62% | EXIT | |
| 3 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 5.00% | — | +60.88% | |
| 4 | ACLXGBX | Arcellx INC | Stock-Other | 4.79% | -1.70% | EXIT | |
| 5 | NUVL | Nuvalent Inc-a | Stock-Other | 3.66% | — | -4.61% | |
| 6 | INBXUSD | Inhibrx INC | Stock-Other | 2.60% | — | — | |
| 7 | ✓ | Fusion Pharmaceuticals INC | Stock-Other | 2.55% | — | +148.07% | |
| 8 | RYTM | Rhythm Pharmaceuticals INC | Stock-Other | 2.48% | -0.83% | +51.74% | |
| 9 | APGE | Apogee Therapeutics INC | Stock-Other | 2.40% | -0.61% | +12.72% | |
| 10 | PCVX | Vaxcyte INC | Stock-Other | 2.31% | — | +77.56% | |
| 11 | SLNOEUR | Soleno Therapeutics INC | Stock-Other | 2.30% | — | — | |
| 12 | MDT | Medtronic plc | Stock-Healthcare | 2.18% | — | +46.37% | |
| 13 | MDGL | Madrigal Pharmaceuticals INC | Stock-Healthcare | 2.01% | — | +184.45% | |
| 14 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 1.95% | — | +15.59% | |
| 15 | NBIX | Neurocrine Biosciences INC | Stock-Healthcare | 1.94% | -0.67% | +197.06% | |
| 16 | IMVT | Immunovant INC | Stock-Other | 1.73% | — | +31.58% | |
| 17 | SYRE | Spyre Therapeutics INC | Stock-Other | 1.70% | +1.94% | -1.92% | |
| 18 | BHVN | Biohaven Ltd. | Stock-Other | 1.65% | — | — | |
| 19 | SLDB | Solid Biosciences INC | Stock-Other | 1.61% | +0.49% | +97.56% | |
| 20 | CATBUSD | Astria Therapeutics INC | Stock-Other | 1.60% | -1.51% | EXIT | |
| 21 | AXSM | Axsome Therapeutics INC | Stock-Healthcare | 1.54% | — | +6.49% | |
| 22 | VKTX | Viking Therapeutics INC | Stock-Healthcare | 1.43% | — | — | |
| 23 | EOLS | Evolus INC | Stock-Other | 1.41% | — | +45.17% | |
| 24 | LYRAGBP | Lyra Therapeutics INC | Stock-Other | 1.39% | — | — | |
| 25 | IRON | Disc Medicine INC | Stock-Other | 1.35% | -0.64% | EXIT | |
| 26 | CRGX | Cargo Therapeutics INC | Stock-Other | 1.35% | — | +0.33% | |
| 27 | ITCIEUR | Intra-cellular Therapies INC | Stock-Other | 1.28% | — | +877.18% | |
| 28 | NTRA | Natera INC | Stock-Healthcare | 1.21% | — | -10.94% | |
| 29 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 1.21% | — | +17.58% | |
| 30 | MGTX | MeiraGTx Holdings plc | Stock-Other | 1.20% | — | — | |
| 31 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 1.19% | — | +16.33% | |
| 32 | VRDN | Viridian Therapeutics INC | Stock-Other | 1.12% | -1.24% | +111.37% | |
| 33 | VRNA | Verona Pharma PLC - Adr | Stock-Other | 1.06% | — | -2.71% | |
| 34 | APLT | Applied Therapeutics INC | Stock-Other | 1.01% | — | +85.69% | |
| 35 | CGON | Cg Oncology INC | Stock-Other | 1.00% | — | — | |
| 36 | AORT | Artivion INC | Stock-Other | 0.99% | -0.23% | +186.57% | |
| 37 | ARVN | Arvinas INC | Stock-Other | 0.89% | — | +249.24% | |
| 38 | CELC | Celcuity INC | Stock-Other | 0.89% | +1.35% | +59.47% | |
| 39 | PRAX | Praxis Precision Medicines I | Stock-Other | 0.88% | +2.33% | — | |
| 40 | RCKT | Rocket Pharmaceuticals INC | Stock-Other | 0.85% | — | +5.49% | |
| 41 | ✓ | Immatics NV | Stock-Other | 0.84% | — | +31.24% | |
| 42 | TARS | Tarsus Pharmaceuticals INC | Stock-Other | 0.82% | — | — | |
| 43 | BBIO | Bridgebio Pharma INC | Stock-Healthcare | 0.76% | — | -19.26% | |
| 44 | ADMA | Adma Biologics INC | Stock-Healthcare | 0.74% | — | — | |
| 45 | EWTX | Edgewise Therapeutics INC | Stock-Other | 0.74% | +0.75% | +317.54% | |
| 46 | ✓ | Verrica Pharmaceuticals INC | Stock-Other | 0.74% | — | — | |
| 47 | ISRG | Intuitive Surgical INC | Stock-Healthcare | 0.71% | — | +85.09% | |
| 48 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 0.67% | — | -18.95% | |
| 49 | NAUT | Nautilus Biotechnology INC | Stock-Other | 0.65% | +0.51% | — | |
| 50 | AKRO | Akero Therapeutics INC | Stock-Other | 0.61% | — | +43.37% |