CIK: 0001306923
Total reported value
$653.9M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | INSM | Insmed INC | Stock-Healthcare | 17.15% | -1.47% | -17.39% | |
| 2 | AM6 | Amicus Therapeutics INC | Stock-Other | 11.18% | -7.86% | -5.93% | |
| 3 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 10.87% | -0.25% | -2.09% | |
| 4 | UTHR | United Therapeutics CORP | Stock-Healthcare | 8.51% | +1.75% | -15.02% | |
| 5 | ACAD | Acadia Pharmaceuticals INC | Stock-Healthcare | 7.82% | +0.54% | +8.90% | |
| 6 | ALNY | Alnylam Pharmaceuticals INC | Stock-Healthcare | 5.13% | — | — | |
| 7 | BIIB | Biogen INC | Stock-Healthcare | 4.51% | -0.55% | -16.94% | |
| 8 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 3.96% | — | — | |
| 9 | NVCR | NovoCure Limited | Stock-Healthcare | 3.76% | -0.21% | +37.18% | |
| 10 | PRTA | Prothena Corporation plc | Stock-Other | 3.73% | +0.04% | — | |
| 11 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 3.49% | +0.71% | — | |
| 12 | EHTH | Ehealth INC | Stock-Other | 2.74% | -0.69% | -20.00% | |
| 13 | PTCT | Ptc Therapeutics INC | Stock-Healthcare | 2.70% | +0.04% | +46.11% | |
| 14 | STAA | Staar Surgical Co | Stock-Other | 1.88% | — | -54.13% | |
| 15 | ANAB | Anaptysbio INC | Stock-Other | 1.73% | +0.75% | — | |
| 16 | ALKS | Alkermes plc | Stock-Healthcare | 1.29% | +0.37% | -24.79% | |
| 17 | ALGN | Align Technology INC | Stock-Healthcare | 1.22% | +0.19% | — | |
| 18 | GOSS | Gossamer Bio INC | Stock-Other | 0.88% | -1.93% | EXIT | |
| 19 | ✓ | Acelyrin INC | Stock-Other | 0.87% | — | — | |
| 20 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 0.83% | +0.77% | — | |
| 21 | BCYC | Bicycle Therapeutics Plc-adr | Stock-Other | 0.54% | -0.08% | +317.80% | |
| 22 | KPTIEUR | Karyopharm Therapeutics INC | Stock-Other | 0.51% | — | -3.83% | |
| 23 | ✓ | Verve Therapeutics INC | Stock-Other | 0.50% | — | — | |
| 24 | EW | Edwards Lifesciences CORP | Stock-Healthcare | 0.45% | +0.01% | — | |
| 25 | BNTX | Biontech Se-adr | Stock-Other | 0.45% | +0.01% | — | |
| 26 | NVROEUR | Nevro CORP | Stock-Other | 0.43% | — | — | |
| 27 | MIRM | Mirum Pharmaceuticals INC | Stock-Other | 0.41% | +2.87% | — | |
| 28 | NUVB | Nuvation Bio INC | Stock-Other | 0.32% | -0.34% | — | |
| 29 | TVTX | Travere Therapeutics INC | Stock-Other | 0.30% | +0.46% | — | |
| 30 | PYXS | Pyxis Oncology INC | Stock-Other | 0.25% | +0.06% | +510.25% | |
| 31 | VYNE | Vyne Therapeutics INC | Stock-Other | 0.23% | — | — | |
| 32 | ACRS | Aclaris Therapeutics INC | Stock-Other | 0.22% | +0.27% | — | |
| 33 | TSHA | Taysha Gene Therapies INC | Stock-Other | 0.22% | +0.04% | — | |
| 34 | STOK | Stoke Therapeutics INC | Stock-Other | 0.22% | +0.10% | — | |
| 35 | ALDX | Aldeyra Therapeutics INC | Stock-Other | 0.17% | -0.12% | — | |
| 36 | HUM | Humana INC | Stock-Healthcare | 0.16% | -0.03% | — | |
| 37 | JSPR | Jasper Therapeutics INC | Stock-Other | 0.10% | — | — | |
| 38 | ABEO | Abeona Therapeutics INC | Stock-Other | 0.09% | — | +746.21% | |
| 39 | URGN | UroGen Pharma Ltd. | Stock-Other | 0.04% | -0.01% | — | |
| 40 | RLMD | Relmada Therapeutics INC | Stock-Other | 0.04% | — | -32.39% | |
| 41 | TIL | Instil Bio INC | Stock-Other | 0.03% | — | — | |
| 42 | ✓ | Akari Therapeutics PLC | Stock-Other | 0.03% | — | — | |
| 43 | GBIOGBX | Generation Bio Co | Stock-Other | 0.02% | — | — |