NM
NEA Management Company, LLC — 13F Portfolio Report & Top Holdings (Q2 2026)
NEA Management Company, LLCCIK: 0001512848
Sector-focusedContrarianQuality / disciplined sizing
Total reported value
$1.6B
Reporting period: 2026-06-30 · Number of holdings: 26
NEA Management Company, LLC disclosed 26 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $1.6B and a quarterly turnover rate of 47.4%.
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Personality snowflake
- Concentration
- 38.72
- Portfolio Stability
- 47.43
- Momentum
- 0
- Sector conviction
- 100
- Diversification
- 52
- Sizing Uniformity
- 87.44
NEA Management Company, LLC's disclosed holdings carry a Herfindahl concentration index of 0.097 — mathematically equivalent to about 10 equally-sized positions, well below its 26 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 1.26), with a handful of outsized bets alongside many smaller positions.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 4% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govSold out ACLXGBX
Add TRVI
0.0% $88.9M
Add MBX
0.0% $91.6M
Add GLUE
0.0% $59.6M
Trim CELC
-25.2% -$81.9M
Add ZBIO
0.0% $23.5M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | TRVI | Trevi Therapeutics Inc | Stock-Other | 15.53% | +6.56% | — | |
| 2 | MBX | Mbx Biosciences Inc | Stock-Other | 12.56% | +6.43% | — | |
| 3 | GLUE | Monte Rosa Therapeutics Inc | Stock-Other | 11.72% | +4.53% | — | |
| 4 | CELC | Celcuity Inc | Stock-Other | 11.27% | -3.56% | -25.16% | |
| 5 | SGP | Spyglass Pharma Inc | Stock-Other | 10.36% | -0.53% | — | |
| 6 | SVRA | Savara Inc | Stock-Other | 9.49% | +1.89% | — | |
| 7 | ZBIO | Zenas Biopharma Inc | Stock-Other | 6.43% | +1.96% | — | |
| 8 | COUR | Coursera Inc | Stock-Other | 4.57% | +0.31% | — | |
| 9 | AUPH | Aurinia Pharmaceuticals Inc | Stock-Other | 4.24% | +0.90% | — | |
| 10 | CRSP | CRISPR Therapeutics AG | Stock-Healthcare | 3.64% | +0.78% | — | |
| 11 | ORIC | Oric Pharmaceuticals Inc | Stock-Other | 2.81% | -0.16% | — | |
| 12 | PHAT | Phathom Pharmaceuticals Inc | Stock-Other | 1.34% | +0.10% | — | |
| 13 | KRRO | Korro Bio Inc | Stock-Other | 1.08% | +0.24% | — | |
| 14 | ASNSUSD | X4 Pharmaceuticals Inc | Stock-Other | 0.95% | +0.19% | — | |
| 15 | CSBR | Champions Oncology Inc | Stock-Other | 0.66% | +0.10% | — | |
| 16 | NKTX | Nkarta Inc | Stock-Other | 0.64% | +0.21% | — | |
| 17 | CVRX | Cvrx Inc | Stock-Other | 0.63% | -0.46% | -3.54% | |
| 18 | BDTX | Black Diamond Therapeutics I | Stock-Other | 0.52% | -0.02% | — | |
| 19 | KPTI | Karyopharm Therapeutics Inc | Stock-Other | 0.35% | +0.35% | NEW | |
| 20 | IVA | Inventiva SA - Adr | Stock-Other | 0.35% | -0.11% | — | |
| 21 | LONA | Leonabio Inc | Stock-Other | 0.27% | — | — | |
| 22 | ✓ | Senti Biosciences Inc | Stock-Other | 0.26% | +0.09% | — | |
| 23 | MRKR | Marker Therapeutics Inc | Stock-Other | 0.15% | +0.03% | — | |
| 24 | OKUR | Onkure Therapeutics Inc-a | Stock-Other | 0.14% | +0.03% | — | |
| 25 | IMA | Imagenebio Inc | Stock-Other | 0.02% | +0.01% | — | |
| 26 | GOSS | Gossamer Bio Inc | Stock-Other | 0.01% | -0.01% | — |
Portfolio Performance
Performance for Q3 2026
+9.3%
Performance Last 4 Quarters
+40.2%
Based on 79% of reported portfolio value with available pricing
- Stdev
- +36.5%
- Beta
- +1.35
- Alpha
- +2.8%
- Max Drawdown
- -31.5%
- Annualized Perf
- +26.3%
- Batting Avg vs S&P
- +38.9%
- Sortino
- +1.57
- Stutzer
- +0.24
- Treynor
- +0.22
- Sterling
- +0.83
- Calmar
- +0.84
- Information Ratio
- +0.3
- Tracking Error
- +32.3%
- Stdev Down
- +19%
- Winning Months %
- +52.8%
- Losing Months %
- +47.2%
- Best 12 Months
- +104.2%
- Worst 12 Months
- -31.1%
- Efficiency Ratio
- +0.33
- Sharpe
- +0.82
- Stdev Sectors
- 0%
- Skewness
- +0.25
- Kurtosis
- -0.49
- Upside Potential
- +3.44
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 26 | $1.6B | 47 | ||
| 2026 Q1 | 26 | $1.8B | 52 | ||
| 2025 Q4 | 27 | $2.0B | 56 | ||
| 2025 Q3 | 29 | $1.8B | 56 | ||
| 2025 Q2 | 32 | $1.3B | 0 | ||
| 2025 Q1 | 38 | $1.3B | 100 | ||
| 2024 Q4 | 42 | $1.8B | 0 | ||
| 2024 Q3 | 42 | $1.8B | 0 | ||
| 2024 Q2 | 41 | $1.3B | 0 | ||
| 2024 Q1 | 44 | $1.6B | 0 | ||
| 2023 Q4 | 44 | $1.5B | 0 | ||
| 2023 Q3 | 46 | $1.3B | 0 | ||
| 2023 Q2 | 44 | $1.3B | 0 | ||
| 2023 Q1 | 53 | $1.4B | 0 | ||
| 2022 Q4 | 57 | $1.8B | 0 | ||
| 2022 Q3 | 57 | $2.0B | 0 | ||
| 2022 Q2 | 57 | $1.9B | 0 | ||
| 2022 Q1 | 57 | $3.5B | 0 | ||
| 2021 Q4 | 58 | $4.9B | 0 | ||
| 2021 Q3 | 63 | $8.4B | 0 | ||
| 2021 Q2 | 63 | $7.7B | 73 | ||
| 2021 Q1 | 58 | $4.5B | 49 | ||
| 2020 Q4 | 57 | $3.8B | 68 | ||
| 2020 Q3 | 54 | $2.4B | 41 | ||
| 2020 Q2 | 46 | $2.5B | 66 | ||
| 2020 Q1 | 50 | $1.9B | 45 | ||
| 2019 Q4 | 47 | $2.1B | 63 | ||
| 2019 Q3 | 46 | $1.2B | 53 | ||
| 2019 Q2 | 44 | $1.4B | 57 | ||
| 2019 Q1 | 45 | $1.9B | 55 | ||
| 2018 Q4 | 46 | $2.5B | 67 | ||
| 2018 Q3 | 44 | $2.3B | 35 | ||
| 2018 Q2 | 43 | $2.1B | 30 | ||
| 2018 Q1 | 43 | $2.2B | 35 | ||
| 2017 Q4 | 43 | $2.4B | 42 | ||
| 2017 Q3 | 44 | $2.9B | 26 | ||
| 2017 Q2 | 44 | $2.7B | 26 | ||
| 2017 Q1 | 38 | $2.9B | 25 | ||
| 2016 Q4 | 39 | $2.5B | 36 | ||
| 2016 Q3 | 39 | $2.2B | 22 | ||
| 2016 Q2 | 39 | $1.9B | 46 | ||
| 2016 Q1 | 37 | $1.5B | 38 | ||
| 2015 Q4 | 34 | $1.6B | 38 | ||
| 2015 Q3 | 35 | $1.5B | 34 | ||
| 2015 Q2 | 34 | $1.9B | 33 | ||
| 2015 Q1 | 36 | $2.2B | 38 | ||
| 2014 Q4 | 35 | $2.1B | 29 | ||
| 2014 Q3 | 35 | $2.0B | 33 | ||
| 2014 Q2 | 31 | $2.1B | 33 | ||
| 2014 Q1 | 28 | $2.0B | 35 | ||
| 2013 Q4 | 29 | $2.1B | 27 | ||
| 2013 Q3 | 31 | $2.5B | 35 | ||
| 2013 Q2 | 31 | $2.2B | 0 |
Holding changes this quarter
NEA Management Company, LLC's most significant position changes for 2026-06-30: Sold out: Arcellx Inc (ACLXGBX); New buy: Karyopharm Therapeutics Inc (KPTI); Trim: Celcuity Inc (CELC) — shares -25.16%; Trim: Cvrx Inc (CVRX) — shares -3.54%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | TRVI | Trevi Therapeutics Inc | +6.6% | — | Unchanged |
| 2 | MBX | Mbx Biosciences Inc | +6.4% | — | Unchanged |
| 3 | GLUE | Monte Rosa Therapeutics Inc | +4.5% | — | Unchanged |
| 4 | ZBIO | Zenas Biopharma Inc | +2% | — | Unchanged |
| 5 | SVRA | Savara Inc | +1.9% | — | Unchanged |
| 6 | AUPH | Aurinia Pharmaceuticals Inc | +0.9% | — | Unchanged |
| 7 | CRSP | CRISPR Therapeutics AG | +0.8% | — | Unchanged |
| 8 | KPTI | Karyopharm Therapeutics Inc | +0.4% | NEW | New buy |
| 9 | COUR | Coursera Inc | +0.3% | — | Unchanged |
| 10 | KRRO | Korro Bio Inc | +0.2% | — | Unchanged |
| 11 | NKTX | Nkarta Inc | +0.2% | — | Unchanged |
| 12 | ASNSUSD | X4 Pharmaceuticals Inc | +0.2% | — | Unchanged |
| 13 | CSBR | Champions Oncology Inc | +0.1% | — | Unchanged |
| 14 | PHAT | Phathom Pharmaceuticals Inc | +0.1% | — | Unchanged |
| 15 | ✓ | Senti Biosciences Inc | +0.1% | — | Unchanged |
| 16 | MRKR | Marker Therapeutics Inc | 0% | — | Unchanged |
| 17 | OKUR | Onkure Therapeutics Inc-a | 0% | — | Unchanged |
| 18 | IMA | Imagenebio Inc | 0% | — | Unchanged |
| 19 | LONA | Leonabio Inc | — | — | Unchanged |
| 20 | GOSS | Gossamer Bio Inc | 0% | — | Unchanged |
| 21 | BDTX | Black Diamond Therapeutics I | 0% | — | Unchanged |
| 22 | IVA | Inventiva SA - Adr | -0.1% | — | Unchanged |
| 23 | ORIC | Oric Pharmaceuticals Inc | -0.2% | — | Unchanged |
| 24 | CVRX | Cvrx Inc | -0.5% | -3.54% | Trim |
| 25 | SGP | Spyglass Pharma Inc | -0.5% | — | Unchanged |
| 26 | CELC | Celcuity Inc | -3.6% | -25.16% | Trim |
| 27 | ACLXGBX | Arcellx Inc | -19.9% | EXIT | Sold out |
* This report is exclusively curated by the AlphaSMO team. AlphaSMO is the web's most authoritative 13F / Inside Trader database, delivering precise insider trading and institutional holdings insights.
Filing History
FAQ
What is NEA Management Company, LLC and what type of investor is it?
NEA Management Company, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $1.6B, spread across 26 disclosed positions.
What are NEA Management Company, LLC's largest equity positions?
Based on the latest 13F filing, NEA Management Company, LLC's top holdings by market value are:
1. Trevi Therapeutics Inc (TRVI) — $246.6M (15.5%)
2. Mbx Biosciences Inc (MBX) — $199.5M (12.6%)
3. Monte Rosa Therapeutics Inc (GLUE) — $186.2M (11.7%)
4. Celcuity Inc (CELC) — $179.0M (11.3%)
5. Spyglass Pharma Inc (SGP) — $164.6M (10.4%)
What changes did NEA Management Company, LLC make in its most recent portfolio filing?
In the latest reported quarter, NEA Management Company, LLC made 4 notable position adjustments: 1 new positions were initiated, 0 existing holdings were added to, 2 positions were partially reduced, and 1 were completely exited. The largest of these moves: Sold out: Arcellx Inc (ACLXGBX); New buy: Karyopharm Therapeutics Inc (KPTI); Trim: Celcuity Inc (CELC) — shares -25.16%; Trim: Cvrx Inc (CVRX) — shares -3.54%
What sectors does NEA Management Company, LLC focus on?
NEA Management Company, LLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
NEA Management Company, LLC returned an annualized 26.3% over the trailing 36 months — outperforming the S&P 500 by 2.8 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 1.35 (more volatile than the market) and a 39% quarterly batting average against the index.
Its portfolio is moderately concentrated and moderately active, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 47 over the past 4 quarters — a shift toward more active trading.
It has added to its GLUE position over the past two quarters (+$65.5M, now $186.2M), while trimming CELC over the same stretch (-$173.7M, still holding $179.0M).
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Developer Access
Access NEA Management Company, LLC's institutional profile programmatically:
REST API
curl https://alphasmo.com/api/v1/institutions/nea-management-company-llcCLI
npx alphasmo institutions get nea-management-company-llc