IB
International Biotechnology Trust PLC Historical SEC 13F Holdings & Archive (Q3 2023)
International Biotechnology Trust PLCCIK: 0000942257
Diversified strategySector-focusedLong-term holder
Total reported value
$296.8M
Reporting period: 2023-09-30 · Number of holdings: 65
INTERNATIONAL BIOTECHNOLOGY TRUST PLC disclosed 65 holdings in its latest 13F filing for the period ending 2023-09-30, with total reported value of $296.8M and a quarterly turnover rate of 0.0%.
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Personality snowflake
- Concentration
- 13.36
- Portfolio Stability
- 0
- Momentum
- 50
- Sector conviction
- 100
- Diversification
- 100
- Sizing Uniformity
- 89.09
International Biotechnology Trust PLC's disclosed holdings carry a Herfindahl concentration index of 0.033 — mathematically equivalent to about 30 equally-sized positions, well below its 65 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 1.09), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 56% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govNo holding changes this quarter
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | AMGN | Amgen Inc | Stock-Healthcare | 7.17% | — | -32.41% | |
| 2 | INCY | Incyte CORP | Stock-Healthcare | 6.97% | — | — | |
| 3 | GILD | Gilead Sciences Inc | Stock-Healthcare | 5.90% | — | +61.56% | |
| 4 | ITCIEUR | Intra-cellular Therapies Inc | Stock-Other | 5.57% | — | +79.73% | |
| 5 | BMRN | Biomarin Pharmaceutical Inc | Stock-Healthcare | 4.58% | — | +161.96% | |
| 6 | SUPN | Supernus Pharmaceuticals Inc | Stock-Healthcare | 3.96% | — | -18.53% | |
| 7 | VERA | Vera Therapeutics Inc | Stock-Other | 3.50% | — | -22.24% | |
| 8 | BIIB | Biogen Inc | Stock-Healthcare | 3.48% | — | +265.45% | |
| 9 | HRMY | Harmony Biosciences Holdings | Stock-Other | 3.47% | — | -44.87% | |
| 10 | MRTXEUR | Mirati Therapeutics Inc | Stock-Other | 3.17% | — | -16.92% | |
| 11 | RARE | Ultragenyx Pharmaceutical In | Stock-Other | 3.00% | — | +212.36% | |
| 12 | QURE | uniQure N.V. | Stock-Other | 2.81% | — | +7909.68% | |
| 13 | AUPH | Aurinia Pharmaceuticals Inc | Stock-Other | 2.72% | — | +81.43% | |
| 14 | UTHR | United Therapeutics CORP | Stock-Healthcare | 2.58% | — | -35.63% | |
| 15 | VRTX | Vertex Pharmaceuticals Inc | Stock-Healthcare | 2.46% | — | — | |
| 16 | REGN | Regeneron Pharmaceuticals | Stock-Healthcare | 2.45% | — | -67.23% | |
| 17 | ILMN | Illumina Inc | Stock-Healthcare | 2.34% | — | — | |
| 18 | ALNY | Alnylam Pharmaceuticals Inc | Stock-Healthcare | 2.20% | — | -54.90% | |
| 19 | AMLX | Amylyx Pharmaceuticals Inc | Stock-Other | 1.82% | — | +1080.00% | |
| 20 | KRYS | Krystal Biotech Inc | Stock-Healthcare | 1.80% | — | +0.32% | |
| 21 | ✓ | Stock-Other | 1.74% | — | +18.68% | ||
| 22 | AXSM | Axsome Therapeutics Inc | Stock-Healthcare | 1.37% | — | — | |
| 23 | ERAS | Erasca Inc | Stock-Other | 1.28% | — | +35.06% | |
| 24 | ACAD | Acadia Pharmaceuticals Inc | Stock-Healthcare | 1.26% | — | +19.01% | |
| 25 | RVNCEUR | Revance Therapeutics Inc | Stock-Other | 1.11% | — | — | |
| 26 | NBIX | Neurocrine Biosciences Inc | Stock-Healthcare | 1.09% | — | -58.07% | |
| 27 | SRPT | Sarepta Therapeutics Inc | Stock-Healthcare | 1.09% | — | +42.02% | |
| 28 | RCKT | Rocket Pharmaceuticals Inc | Stock-Other | 1.08% | — | — | |
| 29 | DNLI | Denali Therapeutics Inc | Stock-Other | 1.07% | — | -18.09% | |
| 30 | AZNN | Astrazeneca Plc-spons Adr | Stock-Other | 1.06% | — | — | |
| 31 | XENE | Xenon Pharmaceuticals Inc | Stock-Other | 1.05% | — | +258.82% | |
| 32 | CRSP | CRISPR Therapeutics AG | Stock-Healthcare | 0.96% | — | — | |
| 33 | MDGL | Madrigal Pharmaceuticals Inc | Stock-Healthcare | 0.90% | — | — | |
| 34 | LEGN | Legend Biotech Corp-adr | Stock-Other | 0.86% | — | — | |
| 35 | HALO | Halozyme Therapeutics Inc | Stock-Healthcare | 0.80% | — | -34.87% | |
| 36 | MRNS* | Marinus Pharmaceuticals Inc | Stock-Other | 0.79% | — | +222.22% | |
| 37 | ONC | Beone Medicines Ltd-adr | Stock-Other | 0.77% | — | +45.98% | |
| 38 | JAZZ | Jazz Pharmaceuticals plc | Stock-Healthcare | 0.75% | — | — | |
| 39 | MIRM | Mirum Pharmaceuticals Inc | Stock-Other | 0.72% | — | — | |
| 40 | IOVA | Iovance Biotherapeutics Inc | Stock-Other | 0.68% | — | +584.62% | |
| 41 | IONS | Ionis Pharmaceuticals Inc | Stock-Healthcare | 0.66% | — | — | |
| 42 | ZLAB | Zai Lab Ltd-adr | Stock-Other | 0.65% | — | — | |
| 43 | GMAB | Genmab A/s -sp Adr | Stock-Other | 0.53% | — | — | |
| 44 | CLDX | Celldex Therapeutics Inc | Stock-Other | 0.45% | — | — | |
| 45 | COGT | Cogent Biosciences Inc | Stock-Other | 0.44% | — | — | |
| 46 | DYN | Dyne Therapeutics Inc | Stock-Other | 0.41% | — | -54.20% | |
| 47 | NVCR | NovoCure Limited | Stock-Healthcare | 0.40% | — | +131.25% | |
| 48 | AM6 | Amicus Therapeutics Inc | Stock-Other | 0.37% | — | — | |
| 49 | CYTK | Cytokinetics Inc | Stock-Healthcare | 0.37% | — | — | |
| 50 | GH | Guardant Health Inc | Stock-Healthcare | 0.36% | — | — |
1–50 of 65
Portfolio Performance
Performance for Q3 2026
+18.9%
Performance Last 4 Quarters
+58.1%
Based on 85% of reported portfolio value with available pricing
- Stdev
- +23.4%
- Beta
- +0.8
- Alpha
- +6.9%
- Max Drawdown
- -15.7%
- Annualized Perf
- +22.3%
- Batting Avg vs S&P
- +50%
- Sortino
- +2.03
- Stutzer
- +0.29
- Treynor
- +0.29
- Sterling
- +1.07
- Calmar
- +1.42
- Information Ratio
- +0.13
- Tracking Error
- +21.2%
- Stdev Down
- +11.2%
- Winning Months %
- +61.1%
- Losing Months %
- +38.9%
- Best 12 Months
- +75.5%
- Worst 12 Months
- -6.3%
- Efficiency Ratio
- +0.43
- Sharpe
- +0.98
- Stdev Sectors
- 0%
- Skewness
- +0.59
- Kurtosis
- +0.32
- Upside Potential
- +3.91
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2023 Q3 | 65 | $296.8M | 0 | ||
| 2023 Q2 | 61 | $328.5M | 0 | ||
| 2023 Q1 | 64 | $358.4M | 0 | ||
| 2022 Q4 | 63 | $323.8M | 0 | ||
| 2022 Q3 | 66 | $311.9M | 0 | ||
| 2022 Q2 | 78 | $9.6M | 0 | ||
| 2022 Q1 | 70 | $443.4M | 0 | ||
| 2021 Q4 | 73 | $448.9M | 0 | ||
| 2021 Q3 | 69 | $414.6M | 0 | ||
| 2021 Q2 | 67 | $378.8M | 100 | ||
| 2021 Q1 | 56 | $378.1M | 63 | ||
| 2020 Q4 | 52 | $366.1M | 53 | ||
| 2020 Q3 | 53 | $309.8M | 35 | ||
| 2020 Q2 | 53 | $300.8M | 44 | ||
| 2020 Q1 | 57 | $219.4M | 53 | ||
| 2019 Q4 | 64 | $277.6M | 53 | ||
| 2019 Q3 | 58 | $216.4M | 38 | ||
| 2019 Q2 | 64 | $269.7M | 57 | ||
| 2019 Q1 | 62 | $270.7M | 72 | ||
| 2018 Q4 | 45 | $161.1M | 60 | ||
| 2018 Q3 | 51 | $210.4M | 41 | ||
| 2018 Q2 | 54 | $260.4M | 45 | ||
| 2018 Q1 | 63 | $256.3M | 57 | ||
| 2017 Q4 | 65 | $283.6M | 44 | ||
| 2017 Q3 | 56 | $256.9M | 56 | ||
| 2017 Q2 | 60 | $263.2M | 51 | ||
| 2017 Q1 | 60 | $261.2M | 57 | ||
| 2016 Q4 | 49 | $222.0M | 0 |
Holding changes this quarter
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|
Filing History
FAQ
What is International Biotechnology Trust PLC and what type of investor is it?
International Biotechnology Trust PLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2023-09-30), the firm manages a tracked equity portfolio valued at approximately $296.8M, spread across 65 disclosed positions.
What are International Biotechnology Trust PLC's largest equity positions?
Based on the latest 13F filing, International Biotechnology Trust PLC's top holdings by market value are:
1. Amgen Inc (AMGN) — $21.3M (7.2%)
2. Incyte CORP (INCY) — $20.7M (7.0%)
3. Gilead Sciences Inc (GILD) — $17.5M (5.9%)
4. Intra-cellular Therapies Inc (ITCIEUR) — $16.5M (5.6%)
5. Biomarin Pharmaceutical Inc (BMRN) — $13.6M (4.6%)
What changes did International Biotechnology Trust PLC make in its most recent portfolio filing?
No notable portfolio changes were recorded for International Biotechnology Trust PLC in the most recent quarter. Holdings appear to have remained relatively stable.
What sectors does International Biotechnology Trust PLC focus on?
International Biotechnology Trust PLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
International Biotechnology Trust PLC returned an annualized 22.3% over the trailing 36 months — outperforming the S&P 500 by 6.9 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.80 (less volatile than the market) and a 50% quarterly batting average against the index.
Its portfolio is broadly diversified and long-term-holding, with 100.0% of the portfolio concentrated in Health Care.
It has added to its GILD position over the past two quarters (+$12.7M, now $17.5M), while trimming PTCT over the same stretch (-$4.1M, still holding $380.6K).
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Developer Access
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