CIK: 0001597549
Total reported value
$152.0M
Reporting period: 2018-03-31 · Number of holdings: 62
Iguana Healthcare Management, LLC disclosed 62 holdings in its latest 13F filing for the period ending 2018-03-31, with total reported value of $152.0M and a quarterly turnover rate of 91.4%.
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Iguana Healthcare Management, LLC's disclosed holdings carry a Herfindahl concentration index of 0.027 — mathematically equivalent to about 37 equally-sized positions, well below its 62 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.82), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 14% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
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Trim ESPR
-39.4% -$3.6M
Trim 48273J107
-85.7% -$2.7M
Add ARNAEUR
+100.0% $2.3M
Trim BIIB
-20.5% -$2.2M
Trim DERMEUR
0.0% -$2.0M
Trim CI
-20.0% -$1.7M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ✓ | Spdr S&P 500 Etf Tr Put Option | ETF-Large Cap & Growth | 8.66% | +8.66% | NEW | |
| 2 | ESPR | Esperion Therapeutics Inc | Stock-Other | 4.76% | -2.32% | -39.39% | |
| 3 | IMMU | Immunomedics Inc | Stock-Other | 3.84% | -0.90% | -11.11% | |
| 4 | GBTUSD | Global Blood Therapeutics In | Stock-Other | 3.65% | — | -8.00% | |
| 5 | HUM | Humana Inc | Stock-Healthcare | 3.54% | — | -11.11% | |
| 6 | BIIB | Biogen Inc | Stock-Healthcare | 3.15% | -1.41% | -20.45% | |
| 7 | MRK | Merck & Co. Inc. | Stock-Healthcare | 2.87% | — | — | |
| 8 | ARNAEUR | Arena Pharmaceuticals Inc | Stock-Other | 2.60% | +1.49% | +100.00% | |
| 9 | ✓ | Shire PLC | Stock-Other | 2.46% | +2.46% | NEW | |
| 10 | CLVSEUR | Clovis Oncology Inc | Stock-Other | 2.43% | — | +16.67% | |
| 11 | ✓ | Esperion Therapeutics Inc Ne | Stock-Other | 2.38% | +2.38% | NEW | |
| 12 | ANAB | Anaptysbio Inc | Stock-Other | 2.23% | — | -18.75% | |
| 13 | CI | The Cigna Group | Stock-Healthcare | 2.21% | -1.10% | -20.00% | |
| 14 | ✓ | Mylan N V | Stock-Other | 2.17% | +1.07% | +100.00% | |
| 15 | CNC | Centene CORP | Stock-Healthcare | 2.11% | +2.11% | NEW | |
| 16 | BMY | Bristol-myers Squibb Co | Stock-Healthcare | 2.08% | — | — | |
| 17 | ALXN | Alexion Pharmaceuticals Inc | Stock-Other | 2.02% | +2.02% | NEW | |
| 18 | RARE | Ultragenyx Pharmaceutical In | Stock-Other | 2.01% | — | +20.00% | |
| 19 | ABT | Abbott Laboratories | Stock-Healthcare | 1.97% | -0.82% | -33.33% | |
| 20 | ✓ | Laboratory Corp. of America | Stock-Other | 1.86% | +1.86% | NEW | |
| 21 | ADMA | Adma Biologics Inc | Stock-Healthcare | 1.82% | — | — | |
| 22 | DXCM | Dexcom Inc | Stock-Healthcare | 1.71% | +1.71% | NEW | |
| 23 | ✓ | Gyre Therapeutics Inc Com | Stock-Other | 1.70% | +1.70% | NEW | |
| 24 | T8S | Tesaro Inc | Stock-Other | 1.69% | — | +28.57% | |
| 25 | ZSANEUR | Zosano Pharma CORP | Stock-Other | 1.66% | +1.66% | NEW | |
| 26 | SGMOQ | Sangamo Therapeutics Inc | Stock-Other | 1.56% | — | -16.67% | |
| 27 | RCKT | Rocket Pharmaceuticals Inc | Stock-Other | 1.54% | +1.54% | NEW | |
| 28 | GSK | GSK plc | Stock-Healthcare | 1.54% | +0.85% | +100.00% | |
| 29 | MDCOUSD | Medicines Company | Stock-Other | 1.52% | — | +16.67% | |
| 30 | ✓ | Armo Biosciences Inc | Stock-Other | 1.48% | +1.48% | NEW | |
| 31 | ✓ | Spdr Series Trust | Stock-Other | 1.44% | +1.44% | NEW | |
| 32 | SRRAEUR | Sierra Oncology Inc | Stock-Other | 1.36% | — | +25.00% | |
| 33 | DPLOEUR | Diplomat Pharmacy Inc | Stock-Other | 1.33% | +0.68% | +100.00% | |
| 34 | MYOKEUR | Myokardia Inc | Stock-Other | 1.28% | — | -20.00% | |
| 35 | CTMX | Cytomx Therapeutics Inc | Stock-Other | 1.22% | — | -13.33% | |
| 36 | IOVA | Iovance Biotherapeutics Inc | Stock-Other | 1.11% | +1.11% | NEW | |
| 37 | MRTXEUR | Mirati Therapeutics Inc | Stock-Other | 1.11% | +1.11% | NEW | |
| 38 | KPTIEUR | Karyopharm Therapeutics Inc | Stock-Other | 1.10% | -0.78% | -58.33% | |
| 39 | VKTX | Viking Therapeutics Inc | Stock-Healthcare | 1.08% | — | +66.67% | |
| 40 | ARWR | Arrowhead Pharmaceuticals In | Stock-Healthcare | 0.95% | +0.95% | NEW | |
| 41 | ✓ | Merus N V | Stock-Other | 0.91% | — | -25.00% | |
| 42 | VYGR | Voyager Therapeutics Inc | Stock-Other | 0.87% | — | +40.00% | |
| 43 | AKAOQ | Achaogen Inc | Stock-Other | 0.85% | — | +33.33% | |
| 44 | ✓ | Corium Intl Inc | Stock-Other | 0.83% | — | +22.22% | |
| 45 | INCY | Incyte CORP | Stock-Healthcare | 0.82% | — | +50.00% | |
| 46 | CTLTEUR | Catalent Inc | Stock-Other | 0.81% | — | — | |
| 47 | CERNCHF | Cerner CORP | Stock-Other | 0.76% | +0.76% | NEW | |
| 48 | ADVMCHF | Adverum Biotechnologies Inc | Stock-Other | 0.76% | — | — | |
| 49 | XNCR | Xencor Inc | Stock-Other | 0.69% | +0.69% | NEW | |
| 50 | KURA | Kura Oncology Inc | Stock-Other | 0.62% | +0.62% | NEW |
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2018 Q1 | 62 | $152.0M | 91 | ||
| 2017 Q4 | 61 | $153.6M | 63 | ||
| 2017 Q3 | 68 | $183.5M | 76 | ||
| 2017 Q2 | 62 | $176.9M | 82 | ||
| 2017 Q1 | 69 | $202.2M | 77 | ||
| 2016 Q4 | 60 | $167.3M | 94 | ||
| 2016 Q3 | 74 | $281.3M | 87 | ||
| 2016 Q2 | 82 | $245.8M | 100 | ||
| 2016 Q1 | 75 | $272.9M | 100 | ||
| 2015 Q4 | 64 | $303.9M | 100 | ||
| 2015 Q3 | 71 | $254.3M | 84 | ||
| 2015 Q2 | 69 | $317.0M | 100 | ||
| 2015 Q1 | 62 | $237.7M | 100 | ||
| 2014 Q4 | 59 | $206.9M | 75 | ||
| 2014 Q3 | 62 | $187.2M | 89 | ||
| 2014 Q2 | 64 | $214.4M | 92 | ||
| 2014 Q1 | 74 | $216.3M | 100 | ||
| 2013 Q4 | 70 | $175.5M | 0 |
Iguana Healthcare Management, LLC's most significant position changes for 2018-03-31: New buy: Spdr S&P 500 Etf Tr Put Option; Sold out: Celgene CORP (CELG); Sold out: Aerie Pharmaceuticals Inc (AERIEUR); Sold out: Abbvie Inc (ABBV); New buy: Shire PLC.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ARNAEUR | Arena Pharmaceuticals Inc | +1.5% | +100.00% | Add |
| 2 | ✓ | Mylan N V | +1.1% | +100.00% | Add |
| 3 | GSK | GSK plc | +0.9% | +100.00% | Add |
| 4 | DPLOEUR | Diplomat Pharmacy Inc | +0.7% | +100.00% | Add |
| 5 | KPTIEUR | Karyopharm Therapeutics Inc | -0.8% | -58.33% | Trim |
| 6 | ABT | Abbott Laboratories | -0.8% | -33.33% | Trim |
| 7 | IMMU | Immunomedics Inc | -0.9% | -11.11% | Trim |
| 8 | CI | The Cigna Group | -1.1% | -20.00% | Trim |
| 9 | DERMEUR | Dermira Inc | -1.3% | — | Unchanged |
| 10 | BIIB | Biogen Inc | -1.4% | -20.45% | Trim |
| 11 | ✓ | K2m Group Holdings Inc | -1.7% | -85.71% | Trim |
| 12 | ESPR | Esperion Therapeutics Inc | -2.3% | -39.39% | Trim |
| 13 | ✓ | Spdr S&P 500 Etf Tr Put Option | — | NEW | New buy |
| 14 | CELG | Celgene CORP | — | EXIT | Sold out |
| 15 | AERIEUR | Aerie Pharmaceuticals Inc | — | EXIT | Sold out |
| 16 | ABBV | Abbvie Inc | — | EXIT | Sold out |
| 17 | ✓ | Shire PLC | — | NEW | New buy |
| 18 | ✓ | Esperion Therapeutics Inc Ne | — | NEW | New buy |
| 19 | CNC | Centene CORP | — | NEW | New buy |
| 20 | ALXN | Alexion Pharmaceuticals Inc | — | NEW | New buy |
| 21 | ✓ | Laboratory Corp. of America | — | NEW | New buy |
| 22 | ✓ | Juno Therapeutics | — | EXIT | Sold out |
| 23 | ZBH | Zimmer Biomet Holdings Inc | — | EXIT | Sold out |
| 24 | DXCM | Dexcom Inc | — | NEW | New buy |
| 25 | ✓ | Gyre Therapeutics Inc Com | — | NEW | New buy |
| 26 | ZSANEUR | Zosano Pharma CORP | — | NEW | New buy |
| 27 | XENTEUR | Intersect Ent Inc | — | EXIT | Sold out |
| 28 | RCKT | Rocket Pharmaceuticals Inc | — | NEW | New buy |
| 29 | DHR | Danaher CORP | — | EXIT | Sold out |
| 30 | ✓ | Armo Biosciences Inc | — | NEW | New buy |
| 31 | ✓ | Spdr Series Trust | — | NEW | New buy |
| 32 | IONS | Ionis Pharmaceuticals Inc | — | EXIT | Sold out |
| 33 | SUPN | Supernus Pharmaceuticals Inc | — | EXIT | Sold out |
| 34 | PFE | Pfizer Inc | — | EXIT | Sold out |
| 35 | WVE | Wave Life Sciences Ltd. | — | EXIT | Sold out |
| 36 | AKCAEUR | Akcea Therapeutics Inc | — | EXIT | Sold out |
| 37 | PBYI | Puma Biotechnology Inc | — | EXIT | Sold out |
| 38 | ✓ | Clovis Oncology Inc | — | EXIT | Sold out |
| 39 | IOVA | Iovance Biotherapeutics Inc | — | NEW | New buy |
| 40 | MRTXEUR | Mirati Therapeutics Inc | — | NEW | New buy |
| 41 | ✓ | Avexis Inc | — | EXIT | Sold out |
| 42 | ✓ | — | EXIT | Sold out | |
| 43 | ✓ | Ablynx NV - Adr | — | EXIT | Sold out |
| 44 | ARWR | Arrowhead Pharmaceuticals In | — | NEW | New buy |
| 45 | BSX | Boston Scientific CORP | — | EXIT | Sold out |
| 46 | CERNCHF | Cerner CORP | — | NEW | New buy |
| 47 | XNCR | Xencor Inc | — | NEW | New buy |
| 48 | RGNX | Regenxbio Inc | — | EXIT | Sold out |
| 49 | KURA | Kura Oncology Inc | — | NEW | New buy |
| 50 | LHCGUSD | Lhc Group Inc | — | EXIT | Sold out |
Iguana Healthcare Management, LLC's portfolio is broadly diversified and fast-trading, with 100.0% of the portfolio concentrated in Health Care.
It has added to its ARNAEUR position over the past two quarters (+$2.4M, now $4.0M), while trimming K2M GROUP HOLDINGS INC over the same stretch (-$3.8M, still holding $474.0K).
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