FC
Foresite Capital Management V, LLC — 13F Filing & Top Stock Positions (Q2 2026)
Foresite Capital Management V, LLCCIK: 0001792206
Concentrated strategySector-focusedMomentum follower
Total reported value
$362.2M
Reporting period: 2026-06-30 · Number of holdings: 9
Foresite Capital Management V, LLC disclosed 9 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $362.2M and a quarterly turnover rate of 31.1%.
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Personality snowflake
- Concentration
- 100
- Portfolio Stability
- 31.11
- Momentum
- 100
- Sector conviction
- 100
- Diversification
- 18
- Sizing Uniformity
- 87.17
Foresite Capital Management V, LLC's disclosed holdings carry a Herfindahl concentration index of 0.274 — mathematically equivalent to about 4 equally-sized positions, well below its 9 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 1.28), with a handful of outsized bets alongside many smaller positions.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 9.9 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 7% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govAdd PHVS
+242.1% $17.5M
Trim CGON
+7.5% $8.7M
New buy 67613T104
Trim ALMS
0.0% $36.0M
Trim LYEL
-0.1% -$2.9M
Add HIMS
0.0% $10.3M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ALMS | Alumis Inc | Stock-Other | 45.81% | -2.13% | — | |
| 2 | CGON | Cg Oncology Inc | Stock-Other | 21.17% | -3.91% | +7.47% | |
| 3 | IRON | Disc Medicine Inc | Stock-Other | 7.55% | -1.28% | — | |
| 4 | HIMS | Hims & Hers Health Inc | Stock-Healthcare | 7.07% | +1.42% | — | |
| 5 | PHVS | Pharvaris N.V. | Stock-Other | 6.34% | +4.32% | +242.12% | |
| 6 | EIKN | Eikon Therapeutics Inc | Stock-Other | 4.75% | -0.40% | — | |
| 7 | ✓ | Stock-Other | 3.68% | +3.68% | NEW | ||
| 8 | LYEL | Lyell Immunopharma Inc | Stock-Other | 1.85% | -1.68% | -0.14% | |
| 9 | NRIX | Nurix Therapeutics Inc | Stock-Other | 1.77% | +0.25% | — |
Portfolio Performance
Performance for Q3 2026
+9.2%
Performance Last 4 Quarters
+185.2%
- Stdev
- +65%
- Beta
- +2.14
- Alpha
- +26%
- Max Drawdown
- -38.7%
- Annualized Perf
- +68%
- Batting Avg vs S&P
- +48.5%
- Sortino
- +2.63
- Stutzer
- +0.34
- Treynor
- +0.33
- Sterling
- +2.06
- Calmar
- +1.76
- Information Ratio
- +0.81
- Tracking Error
- +61.3%
- Stdev Down
- +26.9%
- Winning Months %
- +60.6%
- Losing Months %
- +39.4%
- Best 12 Months
- +282.3%
- Worst 12 Months
- -32.5%
- Efficiency Ratio
- +0.69
- Sharpe
- +1.09
- Stdev Sectors
- 0%
- Skewness
- +1.02
- Kurtosis
- +1.27
- Upside Potential
- +4.42
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 9 | $362.2M | 31 | ||
| 2026 Q1 | 9 | $271.0M | 70 | ||
| 2025 Q4 | 7 | $164.4M | 50 | ||
| 2025 Q3 | 6 | $108.7M | 61 | ||
| 2025 Q2 | 6 | $80.7M | 0 | ||
| 2025 Q1 | 6 | $87.6M | 100 | ||
| 2024 Q4 | 6 | $120.2M | 0 | ||
| 2024 Q3 | 5 | $143.9M | 0 | ||
| 2024 Q2 | 5 | $156.6M | 0 | ||
| 2024 Q1 | 5 | $106.5M | 0 | ||
| 2023 Q4 | 5 | $73.4M | 0 | ||
| 2023 Q3 | 7 | $62.7M | 0 | ||
| 2023 Q2 | 10 | $136.9M | 0 | ||
| 2023 Q1 | 11 | $135.3M | 0 | ||
| 2022 Q4 | 11 | $128.8M | 0 | ||
| 2022 Q3 | 14 | $130.1M | 0 | ||
| 2022 Q2 | 14 | $143.1M | 0 | ||
| 2022 Q1 | 17 | $244.9M | 0 | ||
| 2021 Q4 | 16 | $407.0M | 0 | ||
| 2021 Q3 | 17 | $321.8M | 0 | ||
| 2021 Q2 | 17 | $254.2M | 100 | ||
| 2021 Q1 | 20 | $340.2M | 100 | ||
| 2020 Q4 | 12 | $135.0M | 0 |
💡
Data Source Notice: AlphaSMO is the web's most authoritative 13F / Inside Trader database. Institutional holdings and insider trades presented here are precisely computed to deliver accurate portfolio reporting.
Holding changes this quarter
Foresite Capital Management V, LLC's most significant position changes for 2026-06-30: New buy: ; Sold out: Maze Therapeutics Inc (MAZE); Add: Pharvaris N.V. (PHVS) — shares +242.12%; Add: Cg Oncology Inc (CGON) — shares +7.47%; Trim: Lyell Immunopharma Inc (LYEL) — shares -0.14%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | PHVS | Pharvaris N.V. | +4.3% | +242.12% | Add |
| 2 | ✓ | +3.7% | NEW | New buy | |
| 3 | HIMS | Hims & Hers Health Inc | +1.4% | — | Unchanged |
| 4 | NRIX | Nurix Therapeutics Inc | +0.3% | — | Unchanged |
| 5 | MAZE | Maze Therapeutics Inc | -0.3% | EXIT | Sold out |
| 6 | EIKN | Eikon Therapeutics Inc | -0.4% | — | Unchanged |
| 7 | IRON | Disc Medicine Inc | -1.3% | — | Unchanged |
| 8 | LYEL | Lyell Immunopharma Inc | -1.7% | -0.14% | Trim |
| 9 | ALMS | Alumis Inc | -2.1% | — | Unchanged |
| 10 | CGON | Cg Oncology Inc | -3.9% | +7.47% | Add |
Filing History
FAQ
What is Foresite Capital Management V, LLC and what type of investor is it?
Foresite Capital Management V, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $362.2M, spread across 9 disclosed positions.
What are Foresite Capital Management V, LLC's largest equity positions?
Based on the latest 13F filing, Foresite Capital Management V, LLC's top holdings by market value are:
1. Alumis Inc (ALMS) — $165.9M (45.8%)
2. Cg Oncology Inc (CGON) — $76.7M (21.2%)
3. Disc Medicine Inc (IRON) — $27.4M (7.5%)
4. Hims & Hers Health Inc (HIMS) — $25.6M (7.1%)
5. Pharvaris N.V. (PHVS) — $23.0M (6.3%)
What changes did Foresite Capital Management V, LLC make in its most recent portfolio filing?
In the latest reported quarter, Foresite Capital Management V, LLC made 5 notable position adjustments: 1 new positions were initiated, 2 existing holdings were added to, 1 positions were partially reduced, and 1 were completely exited. The largest of these moves: New buy: ; Sold out: Maze Therapeutics Inc (MAZE); Add: Pharvaris N.V. (PHVS) — shares +242.12%; Add: Cg Oncology Inc (CGON) — shares +7.47%; Trim: Lyell Immunopharma Inc (LYEL) — shares -0.14%
What sectors does Foresite Capital Management V, LLC focus on?
Foresite Capital Management V, LLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
Foresite Capital Management V, LLC returned an annualized 68.0% over the trailing 33 months — outperforming the S&P 500 by 26.0 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 2.14 (more volatile than the market) and a 48% quarterly batting average against the index.
Its portfolio is concentrated and moderately active, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 31 over the past 4 quarters — a shift toward more active trading.
It has added to its ALMS position over the past two quarters (+$109.5M, now $165.9M), while trimming LYEL over the same stretch (-$8.0M, still holding $6.7M).
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Developer Access
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REST API
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