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CIK: 0001009258
Total reported value
$9.6B
$9.6B
150 檔
31.5%
During the Q4 2025 filing period, Deerfield Management Company, L.p. (CIK: 0001009258) submitted its Form 13F report to the U.S. SEC, disclosing a tracked public equity portfolio valued at $9.6B across 150 reported positions.
Deerfield Management Company, L.p. executed strategic sector rebalancing during Q4 2025, establishing 33 new positions while fully exiting 35 holdings and trimming 43 positions.
In terms of portfolio concentration, the top 5 core holdings (including NUVL, BKD 3.5 10-15-29, COGT) accounted for 31.5% of total reported equity market value during Q4 2025.
Top New Position Initiated
BKD 3.5 10-15-29
市值: $427.5M
Top Position Liquidated / Trimmed
MERUS N V
前期市值: $286.9M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | NUVL | Nuvalent Inc-a | Stock-Other | 22.16% | +1.37% | -4.13% | |
| 2 | BKD 3.5 10-15-29Bond | Brookdale Senior Living | Bond | 5.46% | +0.15% | — | |
| 3 | COGT | Cogent Biosciences Inc | Stock-Other | 4.10% | -2.09% | -0.10% | |
| 4 | PRAX | Praxis Precision Medicines I | Stock-Other | 3.40% | -0.30% | +7.43% | |
| 5 | CNC | Centene CORP | Stock-Healthcare | 3.39% | +0.99% | -28.72% | |
| 6 | VTRS | Viatris Inc | Stock-Healthcare | 3.21% | +0.13% | -16.15% | |
| 7 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 2.94% | +2.03% | -20.70% | |
| 8 | UTHR | United Therapeutics CORP | Stock-Healthcare | 2.65% | -0.62% | — | |
| 9 | VERA | Vera Therapeutics Inc | Stock-Other | 2.63% | -0.02% | +11.49% | |
| 10 | MIRM 4 05-01-29Bond | Mirum Pharmaceuticals | Bond | 2.31% | -2.47% | EXIT | |
| 11 | CELC | Celcuity Inc | Stock-Other | 2.18% | -0.73% | +133.66% | |
| 12 | NBIX | Neurocrine Biosciences Inc | Stock-Healthcare | 2.15% | -0.95% | EXIT | |
| 13 | IONS | Ionis Pharmaceuticals Inc | Stock-Healthcare | 2.00% | -0.11% | — | |
| 14 | NAMS | NewAmsterdam Pharma Company N.V. | Stock-Other | 1.87% | -0.10% | -2.39% | |
| 15 | INSP | Inspire Medical Systems Inc | Stock-Healthcare | 1.77% | -1.04% | +43.73% | |
| 16 | LEGN | Legend Biotech Corp-adr | Stock-Other | 1.65% | +0.81% | +100.25% | |
| 17 | BKD | Brookdale Senior Living Inc | Stock-Other | 1.60% | +0.07% | -0.04% | |
| 18 | INDV | Indivior Pharmaceuticals, Inc. | Stock-Other | 1.55% | — | -51.44% | |
| 19 | ARWR | Arrowhead Pharmaceuticals In | Stock-Healthcare | 1.55% | +0.02% | +84.59% | |
| 20 | LRMR | Larimar Therapeutics Inc | Stock-Other | 1.49% | -0.76% | — | |
| 21 | CPRX | Catalyst Pharmaceuticals Inc | Stock-Healthcare | 1.46% | -1.15% | EXIT | |
| 22 | AHCO | Adapthealth CORP | Stock-Other | 1.46% | -0.36% | — | |
| 23 | BCRX | Biocryst Pharmaceuticals Inc | Stock-Other | 1.43% | -0.12% | +17.85% | |
| 24 | IONS 1.75 06-15-28Bond | Ionis Pharmaceuticals In | Bond | 1.22% | -0.10% | — | |
| 25 | ALHC 4.25 11-15-29Bond | Alignment Healthcare | Bond | 1.18% | +0.07% | — | |
| 26 | SPRY | Ars Pharmaceuticals Inc | Stock-Other | 1.12% | -0.08% | — | |
| 27 | PHVS | Pharvaris N.V. | Stock-Other | 1.11% | +0.18% | +27.99% | |
| 28 | SVRA | Savara Inc | Stock-Other | 1.04% | — | +70.38% | |
| 29 | IDYA | Ideaya Biosciences Inc | Stock-Other | 0.95% | +0.46% | — | |
| 30 | CERT | Certara Inc | Stock-Other | 0.88% | -0.02% | +15.86% | |
| 31 | BIO | Bio-rad Laboratories-a | Stock-Healthcare | 0.87% | -0.05% | — | |
| 32 | NEO 0.25 01-15-28Bond | Neogenomics Inc | Bond | 0.83% | -0.66% | — | |
| 33 | ACHC | Acadia Healthcare Co Inc | Stock-Other | 0.82% | +0.14% | +280.15% | |
| 34 | BBOT | Bridgebio Oncology Therapeut | Stock-Other | 0.78% | -0.13% | — | |
| 35 | STOK | Stoke Therapeutics Inc | Stock-Other | 0.74% | -0.08% | — | |
| 36 | LNTH | Lantheus Holdings Inc | Stock-Healthcare | 0.70% | +0.13% | — | |
| 37 | GPCR | Structure Therapeutics Inc | Stock-Other | 0.68% | +0.17% | +105.67% | |
| 38 | NVST | Envista Holdings CORP | Stock-Healthcare | 0.63% | -0.05% | -0.59% | |
| 39 | EHABUSD | Enhabit Inc | Stock-Other | 0.56% | -0.79% | EXIT | |
| 40 | KYMR | Kymera Therapeutics Inc | Stock-Other | 0.56% | -0.55% | EXIT | |
| 41 | CDNA | Caredx Inc | Stock-Other | 0.53% | +0.14% | — | |
| 42 | IRON | Disc Medicine Inc | Stock-Other | 0.52% | — | -44.40% | |
| 43 | SION | Sionna Therapeutics Inc | Stock-Other | 0.51% | -0.15% | — | |
| 44 | LIVN 2.5 03-15-29Bond | Livanova PLC | Bond | 0.51% | +0.01% | — | |
| 45 | BLTE | Belite Bio Inc - Adr | Stock-Other | 0.48% | — | — | |
| 46 | DAWNGBX | Day One Biopharmaceuticals I | Stock-Other | 0.44% | -0.94% | EXIT | |
| 47 | PHR | Phreesia Inc | Stock-Other | 0.43% | — | +79.01% | |
| 48 | EMBC | Embecta CORP | Stock-Healthcare | 0.42% | -0.17% | +5.02% | |
| 49 | VCYT | Veracyte Inc | Stock-Other | 0.39% | -0.22% | — | |
| 50 | MRNA | Moderna Inc | Stock-Healthcare | 0.38% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | PRAX | Praxis Precision Medicines I | +2.7% | +7.43% | Add |
| 2 | COGT | Cogent Biosciences Inc | +2.1% | -0.10% | Trim |
| 3 | CELC | Celcuity Inc | +1.6% | +133.66% | Add |
| 4 | ARWR | Arrowhead Pharmaceuticals In | +1% | +84.59% | Add |
| 5 | VERA | Vera Therapeutics Inc | +1% | +11.49% | Add |
| 6 | SVRA | Savara Inc | +0.6% | +70.38% | Add |
| 7 | INSP | Inspire Medical Systems Inc | +0.6% | +43.73% | Add |
| 8 | GPCR | Structure Therapeutics Inc | +0.5% | +105.67% | Add |
| 9 | ACHC | Acadia Healthcare Co Inc | +0.4% | +280.15% | Add |
| 10 | RVMD | Revolution Medicines Inc | +0.3% | -20.70% | Trim |
| 11 | LEGN | Legend Biotech Corp-adr | +0.2% | +100.25% | Add |
| 12 | PHVS | Pharvaris N.V. | +0.2% | +27.99% | Add |
| 13 | SYRE | Spyre Therapeutics Inc | +0.1% | +15.80% | Add |
| 14 | BKD | Brookdale Senior Living Inc | +0.1% | -0.04% | Trim |
| 15 | SION | Sionna Therapeutics Inc | +0.1% | — | Unchanged |
| 16 | KYMR | Kymera Therapeutics Inc | +0.1% | -1.94% | Trim |
| 17 | IDYA | Ideaya Biosciences Inc | +0.1% | — | Unchanged |
| 18 | EWTX | Edgewise Therapeutics Inc | +0.1% | — | Unchanged |
| 19 | CALC | Calcimedica Inc | +0.1% | — | Unchanged |
| 20 | CDNA | Caredx Inc | 0% | — | Unchanged |
| 21 | LH | Labcorp Holdings Inc | 0% | +1207.95% | Add |
| 22 | PHR | Phreesia Inc | 0% | +79.01% | Add |
| 23 | IONS | Ionis Pharmaceuticals Inc | 0% | — | Unchanged |
| 24 | NAMS | NewAmsterdam Pharma Company N.V. | 0% | -2.39% | Trim |
| 25 | BCRX | Biocryst Pharmaceuticals Inc | 0% | +17.85% | Add |
| 26 | BBNX | Beta Bionics Inc | 0% | -19.69% | Trim |
| 27 | TMDX | Transmedics Group Inc | 0% | +99.91% | Add |
| 28 | PODD | Insulet CORP | 0% | +136.96% | Add |
| 29 | VCYT | Veracyte Inc | 0% | — | Unchanged |
| 30 | FHTX | Foghorn Therapeutics Inc | 0% | +12.09% | Add |
| 31 | ALHC | Alignment Healthcare Inc | 0% | +59.65% | Add |
| 32 | ENOV | Enovis CORP | 0% | +83.88% | Add |
| 33 | ANNX | Annexon Inc | 0% | — | Unchanged |
| 34 | HQY | Healthequity Inc | 0% | +129.90% | Add |
| 35 | DXCM | Dexcom Inc | 0% | +47.81% | Add |
| 36 | ✓ | Newamsterdam Pharma Company | 0% | — | Unchanged |
| 37 | SYK | Stryker CORP | 0% | +78.62% | Add |
| 38 | TNDM | Tandem Diabetes Care Inc | 0% | +113.94% | Add |
| 39 | ATEC | Alphatec Holdings Inc | 0% | -12.24% | Trim |
| 40 | EW | Edwards Lifesciences CORP | — | +115.81% | Add |
| 41 | CHE | Chemed CORP | — | +33.25% | Add |
| 42 | RDNT | Radnet Inc | — | +25.15% | Add |
| 43 | AVNS | Avanos Medical Inc | — | +35.93% | Add |
| 44 | MDXG | Mimedx Group Inc | — | +52.97% | Add |
| 45 | BLFS | Biolife Solutions Inc | — | +8.11% | Add |
| 46 | QSIAW | Quantum-si Inc -cw27 | — | — | Unchanged |
| 47 | NUVB-WS | Nuvation Bio Inc -cw27 | — | — | Unchanged |
| 48 | BFLYW | Butterfly Network Inc -cw25 | — | — | Unchanged |
| 49 | HUM | Humana Inc | — | — | Unchanged |
| 50 | PMVP | Pmv Pharmaceuticals Inc | — | — | Unchanged |
According to official SEC Form 13F filings, Deerfield Management Company, L.p. reported a total U.S. public equity portfolio value of $9.6B across 150 disclosed positions in Q4 2025.
During Q4 2025, Deerfield Management Company, L.p.'s top holdings by market value included NUVL (22.2%)、BKD 3.5 10-15-29 (5.5%)、COGT (4.1%). The largest single position, NUVL, represented 22.2% of total portfolio value.
In Q4 2025, Deerfield Management Company, L.p. made 147 total portfolio adjustments, initiating 33 new buys, adding to 36 positions, trimming 43 holdings, and fully liquidating 35 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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