CIK: 0001977548
Total reported value
$389.8M
Reporting period: 2026-06-30 · Number of holdings: 6
Checkpoint Capital L.P. disclosed 6 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $389.8M and a quarterly turnover rate of 36.0%.
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Checkpoint Capital L.P.'s disclosed holdings carry a Herfindahl concentration index of 0.264 — mathematically equivalent to about 4 equally-sized positions, close to its 6 actual disclosed holdings. Value is spread relatively evenly across the portfolio rather than concentrated in a handful of names.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.83), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 4.5 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 61% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
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Add RVMD
+56.3% $51.3M
Trim ARGX
-14.2% $10.1M
Add CYTK
+163.9% $28.6M
Trim RYTM
-3.4% $25.0M
Trim IRON
-16.2% -$766.4K
Sold out SEPN
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | RYTM | Rhythm Pharmaceuticals Inc | Stock-Other | 33.79% | -4.51% | -3.36% | |
| 2 | ARGX | Argenx Se - Adr | Stock-Healthcare | 31.25% | -8.85% | -14.19% | |
| 3 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 19.72% | +10.56% | +56.30% | |
| 4 | CYTK | Cytokinetics Inc | Stock-Healthcare | 10.38% | +6.12% | +163.89% | |
| 5 | IRON | Disc Medicine Inc | Stock-Other | 4.51% | -2.07% | -16.23% | |
| 6 | TRVI | Trevi Therapeutics Inc | Stock-Other | 0.36% | +0.15% | +50.00% |
Performance for Q3 2026
+22.2%
Performance Last 4 Quarters
+54.7%
Checkpoint Capital L.P.'s most significant position changes for 2026-06-30: Sold out: Septerna Inc (SEPN); Sold out: Crinetics Pharmaceuticals In (CRNX); Add: Revolution Medicines Inc (RVMD) — shares +56.30%; Trim: Argenx Se - Adr (ARGX) — shares -14.19%; Add: Cytokinetics Inc (CYTK) — shares +163.89%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | RVMD | Revolution Medicines Inc | +10.6% | +56.30% | Add |
| 2 | CYTK | Cytokinetics Inc | +6.1% | +163.89% | Add |
| 3 | TRVI | Trevi Therapeutics Inc | +0.2% | +50.00% | Add |
| 4 | CRNX | Crinetics Pharmaceuticals In | -0.5% | EXIT | Sold out |
| 5 | SEPN | Septerna Inc | -0.9% | EXIT | Sold out |
| 6 | IRON | Disc Medicine Inc | -2.1% | -16.23% | Trim |
| 7 | RYTM | Rhythm Pharmaceuticals Inc | -4.5% | -3.36% | Trim |
| 8 | ARGX | Argenx Se - Adr | -8.9% | -14.19% | Trim |
Checkpoint Capital L.P. returned an annualized 44.4% over the trailing 30 months — outperforming the S&P 500 by 25.3 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 0.87 (less volatile than the market) and a 60% quarterly batting average against the index.
Its portfolio is concentrated and moderately active, with 100.0% of the portfolio concentrated in Health Care.
Its turnover score has risen from 0 to 36 over the past 4 quarters — a shift toward more active trading.
It has added to its CYTK position over the past two quarters (+$29.9M, now $40.5M), while trimming IRON over the same stretch (-$18.4M, still holding $17.6M).
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