CIK: 0001657134
Total reported value
$188.4M
Reporting period: 2021-12-31 · Number of holdings: 24
Asymmetry Capital Management, L.P. disclosed 24 holdings in its latest 13F filing for the period ending 2021-12-31, with total reported value of $188.4M and a quarterly turnover rate of 0.0%.
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Asymmetry Capital Management, L.P.'s disclosed holdings carry a Herfindahl concentration index of 0.054 — mathematically equivalent to about 19 equally-sized positions, close to its 24 actual disclosed holdings. Value is spread relatively evenly across the portfolio rather than concentrated in a handful of names.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.55), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 19% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
No holding changes this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 8.34% | — | — | |
| 2 | ✓ | Horizon Therapeutics PLC | Stock-Other | 7.87% | — | +451.57% | |
| 3 | UNH | Unitedhealth Group INC | Stock-Healthcare | 7.16% | — | — | |
| 4 | ABBV | Abbvie INC | Stock-Healthcare | 6.79% | — | — | |
| 5 | IQV | Iqvia Holdings INC | Stock-Healthcare | 6.64% | — | — | |
| 6 | CNC | Centene CORP | Stock-Healthcare | 6.48% | — | — | |
| 7 | BLU | Bellus Health INC | Stock-Other | 5.47% | — | +19.40% | |
| 8 | CYTK | Cytokinetics INC | Stock-Healthcare | 5.44% | — | -8.65% | |
| 9 | JNJ | Johnson & Johnson | Stock-Healthcare | 5.06% | — | — | |
| 10 | NTRA | Natera INC | Stock-Healthcare | 5.04% | — | — | |
| 11 | AM6 | Amicus Therapeutics INC | Stock-Other | 4.39% | — | +9.59% | |
| 12 | ARGX | Argenx Se - Adr | Stock-Healthcare | 3.88% | — | — | |
| 13 | KURA | Kura Oncology INC | Stock-Other | 3.73% | — | +158.49% | |
| 14 | APLSUSD | Apellis Pharmaceuticals INC | Stock-Other | 3.50% | — | — | |
| 15 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 3.42% | — | +4.49% | |
| 16 | OPHTEUR | Iveric Bio INC | Stock-Other | 3.34% | — | +5.79% | |
| 17 | QTRX | Quanterix CORP | Stock-Other | 3.22% | — | -11.57% | |
| 18 | 2662247D | Iteos Therapeutics INC | Stock-Other | 2.59% | — | +82.86% | |
| 19 | ✓ | DICE Therapeutics Inc | Stock-Other | 2.49% | — | -32.69% | |
| 20 | ✓ | Avadel Pharmaceuticals PLC | Stock-Other | 1.58% | — | -22.18% | |
| 21 | ACRS | Aclaris Therapeutics INC | Stock-Other | 1.53% | — | -17.88% | |
| 22 | PMVP | Pmv Pharmaceuticals INC | Stock-Other | 1.20% | — | -3.17% | |
| 23 | RGLSUSD | Regulus Therapeutics INC | Stock-Other | 0.46% | — | +94.87% | |
| 24 | ✓ | Bcls Acquisition CORP | Stock-Other | 0.37% | — | -2.64% |
Not enough priced holdings yet to compute performance
| Period | Holdings | Total value | Stability | Top holdings |
|---|---|---|---|---|
| 2021-12-31 | 24 | $188.4M | 0 | |
| 2021-09-30 | 29 | $166.3M | 0 | |
| 2021-06-30 | 30 | $145.5M | 100 | |
| 2021-03-31 | 29 | $193.3M | 100 | |
| 2020-12-31 | 33 | $219.3M | 100 | |
| 2020-09-30 | 34 | $155.6M | 98 | |
| 2020-06-30 | 32 | $130.5M | 88 | |
| 2020-03-31 | 29 | $91.4M | 100 | |
| 2019-12-31 | 33 | $55.8M | 100 | |
| 2019-09-30 | 22 | $46.7M | 100 | |
| 2019-06-30 | 30 | $184.7M | 100 | |
| 2019-03-31 | 25 | $59.8M | 81 | |
| 2018-12-31 | 23 | $36.2M | 100 | |
| 2018-09-30 | 35 | $108.2M | 83 | |
| 2018-06-30 | 36 | $101.7M | 78 | |
| 2018-03-31 | 36 | $79.9M | 56 | |
| 2017-12-31 | 31 | $73.7M | 68 | |
| 2017-09-30 | 32 | $86.2M | 73 | |
| 2017-06-30 | 28 | $84.3M | 81 | |
| 2017-03-31 | 27 | $71.7M | 51 | |
| 2016-12-31 | 20 | $53.8M | 82 | |
| 2016-09-30 | 20 | $57.5M | 77 | |
| 2016-06-30 | 19 | $54.6M | 94 | |
| 2016-03-31 | 16 | $38.4M | 87 | |
| 2015-12-31 | 17 | $66.1M | 100 | |
| 2015-09-30 | 22 | $44.9M | 0 |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|
| Period | Filed | Type | EDGAR |
|---|---|---|---|
| 2021-12-31 | 2022-01-19 | 13F-HR | View on EDGAR |
| 2021-09-30 | 2021-11-04 | 13F-HR | View on EDGAR |
| 2021-06-30 | 2021-07-28 | 13F-HR | View on EDGAR |
| 2021-03-31 | 2021-05-11 | 13F-HR | View on EDGAR |
| 2020-12-31 | 2021-02-11 | 13F-HR | View on EDGAR |
| 2020-09-30 | 2020-11-12 | 13F-HR | View on EDGAR |
| 2020-06-30 | 2020-08-06 | 13F-HR | View on EDGAR |
| 2020-03-31 | 2020-05-13 | 13F-HR | View on EDGAR |
| 2019-12-31 | 2020-02-12 | 13F-HR | View on EDGAR |
| 2019-09-30 | 2019-11-12 | 13F-HR | View on EDGAR |
| 2019-06-30 | 2019-08-07 | 13F-HR | View on EDGAR |
| 2019-03-31 | 2019-05-08 | 13F-HR | View on EDGAR |
| 2018-12-31 | 2019-02-12 | 13F-HR | View on EDGAR |
| 2018-09-30 | 2018-11-08 | 13F-HR | View on EDGAR |
| 2018-06-30 | 2018-08-07 | 13F-HR | View on EDGAR |
| 2018-03-31 | 2018-05-09 | 13F-HR | View on EDGAR |
| 2017-12-31 | 2018-02-14 | 13F-HR | View on EDGAR |
| 2017-09-30 | 2017-11-03 | 13F-HR | View on EDGAR |
| 2017-06-30 | 2017-08-15 | 13F-HR | View on EDGAR |
| 2017-03-31 | 2017-05-12 | 13F-HR | View on EDGAR |
| 2016-12-31 | 2017-02-14 | 13F-HR | View on EDGAR |
| 2016-09-30 | 2016-11-10 | 13F-HR | View on EDGAR |
| 2016-06-30 | 2016-08-05 | 13F-HR | View on EDGAR |
| 2016-03-31 | 2016-04-21 | 13F-HR | View on EDGAR |
| 2015-12-31 | 2016-02-03 | 13F-HR | View on EDGAR |
| 2015-09-30 | 2015-11-09 | 13F-HR | View on EDGAR |
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