7I
72 Investment Holdings, LLC Institutional Portfolio & 13F Holdings (Q2 2026)
72 Investment Holdings, LLCCIK: 0001832749
Concentrated strategyQuality / disciplined sizingLong-term holder
Total reported value
$50.0M
Reporting period: 2026-06-30 · Number of holdings: 5
72 Investment Holdings, LLC disclosed 5 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $50.0M and a quarterly turnover rate of 15.2%.
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Personality snowflake
- Concentration
- 100
- Portfolio Stability
- 15.18
- Momentum
- 50
- Sector conviction
- 0
- Diversification
- 10
- Sizing Uniformity
- 90.69
Sector classification currently covers about 0% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govTrim LENZ
0.0% -$3.5M
Add ANRO
0.0% $2.6M
Add PRAX
0.0% $830.8K
Add KRRO
0.0% $514.9K
Trim CRBU
0.0% -$66.4K
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | PRAX | Praxis Precision Medicines I | Stock-Other | 44.18% | +1.35% | — | |
| 2 | ANRO | Alto Neuroscience Inc | Stock-Other | 35.27% | +5.01% | — | |
| 3 | LENZ | Lenz Therapeutics Inc | Stock-Other | 11.57% | -7.20% | — | |
| 4 | KRRO | Korro Bio Inc | Stock-Other | 7.30% | +0.98% | — | |
| 5 | CRBU | Caribou Biosciences Inc | Stock-Other | 1.67% | -0.15% | — |
Portfolio Performance
Performance for Q3 2026
+13.2%
Performance Last 4 Quarters
+7.1%
- Stdev
- +56.2%
- Beta
- +1.15
- Alpha
- +18.1%
- Max Drawdown
- -36.8%
- Annualized Perf
- +30.6%
- Batting Avg vs S&P
- +47.2%
- Sortino
- +1.47
- Stutzer
- +0.22
- Treynor
- +0.36
- Sterling
- +0.7
- Calmar
- +0.83
- Information Ratio
- +0.39
- Tracking Error
- +54.2%
- Stdev Down
- +28%
- Winning Months %
- +58.3%
- Losing Months %
- +41.7%
- Best 12 Months
- +147.2%
- Worst 12 Months
- -34.1%
- Efficiency Ratio
- +0.28
- Sharpe
- +0.73
- Stdev Sectors
- —
- Skewness
- +0.76
- Kurtosis
- +0.69
- Upside Potential
- +3.33
Reported value over time
Sector allocation
Not enough sector-mapped data yet
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 5 | $50.0M | 15 | ||
| 2026 Q1 | 5 | $49.6M | 26 | ||
| 2025 Q4 | 5 | $50.6M | 100 | ||
| 2025 Q3 | 5 | $67.9M | 62 | ||
| 2025 Q2 | 6 | $38.3M | 0 | ||
| 2025 Q1 | 6 | $35.6M | 100 | ||
| 2024 Q4 | 7 | $49.1M | 0 | ||
| 2024 Q3 | 7 | $46.5M | 0 | ||
| 2024 Q2 | 7 | $39.8M | 0 | ||
| 2024 Q1 | 7 | $67.1M | 0 | ||
| 2023 Q4 | 6 | $22.5M | 0 | ||
| 2023 Q3 | 5 | $14.9M | 0 | ||
| 2023 Q2 | 4 | $12.8M | 0 | ||
| 2023 Q1 | 5 | $211.2M | 0 | ||
| 2022 Q4 | 5 | $217.5M | 0 | ||
| 2022 Q3 | 5 | $126.2M | 0 | ||
| 2022 Q2 | 5 | $64.7M | 0 | ||
| 2022 Q1 | 6 | $91.4M | 0 | ||
| 2021 Q4 | 6 | $112.7M | 0 | ||
| 2021 Q3 | 4 | $80.1M | 0 | ||
| 2021 Q2 | 2 | $63.5M | 40 | 174349U2PRAX | |
| 2021 Q1 | 2 | $66.1M | 100 | 174349U2PRAX | |
| 2020 Q4 | 2 | $742.2M | 0 |
Holding changes this quarter
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ANRO | Alto Neuroscience Inc | +5% | — | Unchanged |
| 2 | PRAX | Praxis Precision Medicines I | +1.4% | — | Unchanged |
| 3 | KRRO | Korro Bio Inc | +1% | — | Unchanged |
| 4 | CRBU | Caribou Biosciences Inc | -0.2% | — | Unchanged |
| 5 | LENZ | Lenz Therapeutics Inc | -7.2% | — | Unchanged |
Filing History
FAQ
What is 72 Investment Holdings, LLC and what type of investor is it?
72 Investment Holdings, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $50.0M, spread across 5 disclosed positions.
What are 72 Investment Holdings, LLC's largest equity positions?
Based on the latest 13F filing, 72 Investment Holdings, LLC's top holdings by market value are:
1. Praxis Precision Medicines I (PRAX) — $22.1M (44.2%)
2. Alto Neuroscience Inc (ANRO) — $17.6M (35.3%)
3. Lenz Therapeutics Inc (LENZ) — $5.8M (11.6%)
4. Korro Bio Inc (KRRO) — $3.6M (7.3%)
5. Caribou Biosciences Inc (CRBU) — $834.4K (1.7%)
What changes did 72 Investment Holdings, LLC make in its most recent portfolio filing?
No notable portfolio changes were recorded for 72 Investment Holdings, LLC in the most recent quarter. Holdings appear to have remained relatively stable.
What sectors does 72 Investment Holdings, LLC focus on?
Sector breakdown data is not yet available for 72 Investment Holdings, LLC. Check back after the next 13F processing cycle.
Investment Profile
72 Investment Holdings, LLC returned an annualized 30.6% over the trailing 36 months — outperforming the S&P 500 by 18.1 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 1.15 (more volatile than the market) and a 47% quarterly batting average against the index.
Its portfolio is concentrated and long-term-holding.
Its turnover score has risen from 0 to 15 over the past 4 quarters — a shift toward more active trading.
It has added to its ANRO position over the past two quarters (+$5.7M, now $17.6M), while trimming LENZ over the same stretch (-$10.5M, still holding $5.8M).
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Developer Access
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REST API
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