VM
VHCP Management II, LLC Historical SEC 13F Holdings & Archive (Q4 2019)
VHCP Management II, LLCCIK: 0001602263
High-turnover traderMomentum followerConcentrated strategy
Total reported value
$379.4M
Reporting period: 2019-12-31 · Number of holdings: 20
VHCP Management II, LLC disclosed 20 holdings in its latest 13F filing for the period ending 2019-12-31, with total reported value of $379.4M and a quarterly turnover rate of 93.6%.
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Personality snowflake
- Concentration
- 86.78
- Portfolio Stability
- 93.57
- Momentum
- 100
- Sector conviction
- 0
- Diversification
- 40
- Sizing Uniformity
- 81.25
Sector classification currently covers about 21% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govAdd CNST
+106.5% $66.0M
Add AXSM
-12.0% $63.2M
Trim H5861P103
-30.1% -$12.8M
Trim BHVN
-35.1% -$4.5M
Trim SWAVUSD
-55.3% -$6.7M
Trim PTGX
-92.5% -$4.9M
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | TXG | 10x Genomics Inc-class A | Stock-Other | 35.91% | +1.60% | — | |
| 2 | AXSM | Axsome Therapeutics Inc | Stock-Healthcare | 21.42% | +14.53% | -11.98% | |
| 3 | CNST | Constellation Pharmaceutical | Stock-Other | 18.64% | +16.85% | +106.51% | |
| 4 | BHVN | Biohaven Ltd. | Stock-Other | 6.64% | -4.69% | -35.07% | |
| 5 | SWAVUSD | Shockwave Medical Inc | Stock-Other | 3.34% | -4.03% | -55.32% | |
| 6 | OPHTEUR | Iveric Bio Inc | Stock-Other | 2.27% | +2.27% | NEW | |
| 7 | 4XC1 | Kalvista Pharmaceuticals Inc | Stock-Other | 1.72% | +0.05% | -2.82% | |
| 8 | ✓ | Obseva SA | Stock-Other | 1.58% | -5.57% | -30.14% | |
| 9 | ✓ | Mersana Therapeutics Inc | Stock-Other | 1.39% | +1.39% | NEW | |
| 10 | SPRO | Spero Therapeutics Inc | Stock-Other | 1.20% | -0.72% | — | |
| 11 | RLMD | Relmada Therapeutics Inc | Stock-Other | 1.18% | +1.18% | NEW | |
| 12 | ADVMCHF | Adverum Biotechnologies Inc | Stock-Other | 1.16% | +1.16% | NEW | |
| 13 | MRNSUSD | Marinus Pharmaceuticals Inc | Stock-Other | 0.85% | -0.02% | — | |
| 14 | FTSVEUR | Forty Seven Inc | Stock-Other | 0.81% | +0.81% | NEW | |
| 15 | MIST | Milestone Pharmaceuticals In | Stock-Other | 0.63% | -0.43% | — | |
| 16 | NXTCEUR | Nextcure Inc | Stock-Other | 0.54% | +0.54% | NEW | |
| 17 | ✓ | Myovant Sciences LTD | Stock-Other | 0.31% | +0.31% | NEW | |
| 18 | ETNBGBP | 89bio Inc | Stock-Other | 0.29% | +0.29% | NEW | |
| 19 | BLPHEUR | Bellerophon Therapeutics Inc | Stock-Other | 0.06% | -0.70% | -84.12% | |
| 20 | PTGX | Protagonist Therapeutics Inc | Stock-Other | 0.06% | -1.89% | -92.45% |
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2019 Q4 | 20 | $379.4M | 94 | ||
| 2019 Q3 | 21 | $262.4M | 81 | ||
| 2019 Q2 | 21 | $317.2M | 38 | ||
| 2019 Q1 | 21 | $341.8M | 48 | ||
| 2018 Q4 | 19 | $233.0M | 53 | ||
| 2018 Q3 | 21 | $374.5M | 30 | ||
| 2018 Q2 | 18 | $334.1M | 84 | ||
| 2018 Q1 | 17 | $414.4M | 46 | ||
| 2017 Q4 | 18 | $417.2M | 41 | ||
| 2017 Q3 | 21 | $361.9M | 54 | ||
| 2017 Q2 | 19 | $250.4M | 47 | ||
| 2017 Q1 | 20 | $244.4M | 41 | ||
| 2016 Q4 | 22 | $208.5M | 28 | ||
| 2016 Q3 | 24 | $194.8M | 35 | ||
| 2016 Q2 | 23 | $165.7M | 30 | ||
| 2016 Q1 | 22 | $152.0M | 62 | ||
| 2015 Q4 | 15 | $121.7M | 0 |
Holding changes this quarter
VHCP Management II, LLC's most significant position changes for 2019-12-31: Sold out: Ascendis Pharma A/S (ASND); Sold out: Ra Pharmaceuticals Inc (RARXEUR); New buy: Iveric Bio Inc (OPHTEUR); Sold out: Biocryst Pharmaceuticals Inc (BCRX); New buy: Mersana Therapeutics Inc.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | CNST | Constellation Pharmaceutical | +16.9% | +106.51% | Add |
| 2 | AXSM | Axsome Therapeutics Inc | +14.5% | -11.98% | Trim |
| 3 | TXG | 10x Genomics Inc-class A | +1.6% | — | Unchanged |
| 4 | 4XC1 | Kalvista Pharmaceuticals Inc | +0.1% | -2.82% | Trim |
| 5 | MRNSUSD | Marinus Pharmaceuticals Inc | 0% | — | Unchanged |
| 6 | MIST | Milestone Pharmaceuticals In | -0.4% | — | Unchanged |
| 7 | BLPHEUR | Bellerophon Therapeutics Inc | -0.7% | -84.12% | Trim |
| 8 | SPRO | Spero Therapeutics Inc | -0.7% | — | Unchanged |
| 9 | PTGX | Protagonist Therapeutics Inc | -1.9% | -92.45% | Trim |
| 10 | SWAVUSD | Shockwave Medical Inc | -4% | -55.32% | Trim |
| 11 | BHVN | Biohaven Ltd. | -4.7% | -35.07% | Trim |
| 12 | ✓ | Obseva SA | -5.6% | -30.14% | Trim |
| 13 | ASND | Ascendis Pharma A/S | — | EXIT | Sold out |
| 14 | RARXEUR | Ra Pharmaceuticals Inc | — | EXIT | Sold out |
| 15 | OPHTEUR | Iveric Bio Inc | — | NEW | New buy |
| 16 | BCRX | Biocryst Pharmaceuticals Inc | — | EXIT | Sold out |
| 17 | ✓ | Mersana Therapeutics Inc | — | NEW | New buy |
| 18 | KNSA | Kiniksa Pharmaceuticals International, plc | — | EXIT | Sold out |
| 19 | LJPC | La Jolla Pharmaceutical Co | — | EXIT | Sold out |
| 20 | RLMD | Relmada Therapeutics Inc | — | NEW | New buy |
| 21 | ADVMCHF | Adverum Biotechnologies Inc | — | NEW | New buy |
| 22 | 1T7 | Tricida Inc | — | EXIT | Sold out |
| 23 | FTSVEUR | Forty Seven Inc | — | NEW | New buy |
| 24 | NXTCEUR | Nextcure Inc | — | NEW | New buy |
| 25 | ✓ | Myovant Sciences LTD | — | NEW | New buy |
| 26 | ETNBGBP | 89bio Inc | — | NEW | New buy |
| 27 | RDUSEUR | Radius Health Inc | — | EXIT | Sold out |
| 28 | PTIEUR | Proteostasis Therapeutics In | — | EXIT | Sold out |
| 29 | ✓ | Prevail Therapeutics Inc | — | EXIT | Sold out |
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Data Source Notice: AlphaSMO is the web's most authoritative 13F / Inside Trader database. Institutional holdings and insider trades presented here are precisely computed to deliver accurate portfolio reporting.
Filing History
FAQ
What is VHCP Management II, LLC and what type of investor is it?
VHCP Management II, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2019-12-31), the firm manages a tracked equity portfolio valued at approximately $379.4M, spread across 20 disclosed positions.
What are VHCP Management II, LLC's largest equity positions?
Based on the latest 13F filing, VHCP Management II, LLC's top holdings by market value are:
1. 10x Genomics Inc-class A (TXG) — $136.2M (35.9%)
2. Axsome Therapeutics Inc (AXSM) — $81.2M (21.4%)
3. Constellation Pharmaceutical (CNST) — $70.7M (18.6%)
4. Biohaven Ltd. (BHVN) — $25.2M (6.6%)
5. Shockwave Medical Inc (SWAVUSD) — $12.7M (3.3%)
What changes did VHCP Management II, LLC make in its most recent portfolio filing?
In the latest reported quarter, VHCP Management II, LLC made 25 notable position adjustments: 8 new positions were initiated, 1 existing holdings were added to, 7 positions were partially reduced, and 9 were completely exited. The largest of these moves: Sold out: Ascendis Pharma A/S (ASND); Sold out: Ra Pharmaceuticals Inc (RARXEUR); New buy: Iveric Bio Inc (OPHTEUR); Sold out: Biocryst Pharmaceuticals Inc (BCRX); New buy: Mersana Therapeutics Inc
What sectors does VHCP Management II, LLC focus on?
VHCP Management II, LLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Health Care: 100.0%
Investment Profile
VHCP Management II, LLC's portfolio is concentrated and fast-trading, with 100.0% of the portfolio concentrated in Health Care.
Its concentration score has risen from 42 to 87 over the past 4 quarters — a shift toward higher-conviction positions.
It has trimmed its SWAVUSD position for two straight quarters, cutting it by $38.8M while still holding $12.7M.
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Developer Access
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REST API
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