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CIK: 0001496201
Total reported value
$766.5M
$766.5M
95 檔
18.9%
As reported in its official Q1 2026 Form 13F filing, Sphera Funds Management LTD.'s tracked investment portfolio stood at $766.5M with 95 total positions.
Sphera Funds Management LTD. executed strategic sector rebalancing during Q1 2026, establishing 20 new positions while fully exiting 23 holdings and trimming 29 positions.
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | MLYS | Mineralys Therapeutics Inc | Stock-Other | 5.76% | -0.59% | +198.43% | |
| 2 | TEVA | Teva Pharmaceutical-sp Adr | Stock-Healthcare | 5.44% | +1.19% | +1.20% | |
| 3 | TSEM | Tower Semiconductor Ltd. | Stock-Tech | 4.06% | -0.38% | +18.95% | |
| 4 | XBI | Ss Spdr S&p Biotech ETF | ETF-Tech | 4.06% | -0.96% | +185.71% | |
| 5 | NVMI | Nova Ltd. | Stock-Other | 3.68% | -1.90% | +11.54% | |
| 6 | CYTK | Cytokinetics Inc | Stock-Healthcare | 3.13% | +0.43% | +226.13% | |
| 7 | BBIO | Bridgebio Pharma Inc | Stock-Healthcare | 2.89% | -0.51% | +127.61% | |
| 8 | BIIB | Biogen Inc | Stock-Healthcare | 2.69% | +2.85% | -2.33% | |
| 9 | RARE | Ultragenyx Pharmaceutical In | Stock-Other | 2.69% | -0.13% | +24.39% | |
| 10 | SNDX | Syndax Pharmaceuticals Inc | Stock-Other | 2.69% | +0.20% | -4.98% | |
| 11 | COGT | Cogent Biosciences Inc | Stock-Other | 2.54% | -0.22% | +10.00% | |
| 12 | SNY | Sanofi-adr | Stock-Healthcare | 2.06% | -0.56% | +12.53% | |
| 13 | AZN | AstraZeneca PLC | Stock-Healthcare | 1.96% | -0.41% | — | |
| 14 | AM6 | Amicus Therapeutics Inc | Stock-Other | 1.39% | -1.39% | EXIT | |
| 15 | CLBT | Cellebrite DI Ltd. | Stock-Other | 1.38% | -1.38% | EXIT | |
| 16 | APLSUSD | Apellis Pharmaceuticals Inc | Stock-Other | 1.37% | -1.37% | EXIT | |
| 17 | PANW | Palo Alto Networks Inc | Stock-Tech | 1.34% | -1.34% | EXIT | |
| 18 | LLY | Eli Lilly & Co | Stock-Healthcare | 1.32% | -0.06% | — | |
| 19 | BCRX | Biocryst Pharmaceuticals Inc | Stock-Other | 1.31% | -0.76% | +3.41% | |
| 20 | CAMT | Camtek Ltd. | Stock-Other | 1.28% | -1.28% | EXIT | |
| 21 | BMRN | Biomarin Pharmaceutical Inc | Stock-Healthcare | 1.26% | +1.19% | -4.83% | |
| 22 | CLDX | Celldex Therapeutics Inc | Stock-Other | 1.23% | -0.06% | +1.59% | |
| 23 | ORA | Ormat Technologies Inc | Stock-Utilities | 1.21% | -0.81% | — | |
| 24 | XENE | Xenon Pharmaceuticals Inc | Stock-Other | 1.17% | -0.34% | — | |
| 25 | SLNOEUR | Soleno Therapeutics Inc | Stock-Other | 1.15% | -1.15% | EXIT | |
| 26 | TNGX | Tango Therapeutics Inc | Stock-Other | 1.14% | -0.10% | -36.91% | |
| 27 | JNJ | Johnson & Johnson | Stock-Healthcare | 1.12% | -0.16% | -19.54% | |
| 28 | SEDG 2.25 07-01-29Bond | Solar Edge Technologies | Bond | 1.10% | -0.09% | — | |
| 29 | ✓ | Immatics NV | Stock-Other | 1.09% | -0.14% | -19.16% | |
| 30 | TRVI | Trevi Therapeutics Inc | Stock-Other | 1.09% | +0.12% | -4.09% | |
| 31 | ORIC | Oric Pharmaceuticals Inc | Stock-Other | 1.08% | +0.13% | -46.47% | |
| 32 | MAZE | Maze Therapeutics Inc | Stock-Other | 1.08% | +0.55% | +216.44% | |
| 33 | GSK | Gsk Plc-spon Adr | Stock-Healthcare | 1.07% | -0.37% | — | |
| 34 | AMZN | Amazon.com Inc | Stock-Consumer Disc | 1.06% | -1.06% | EXIT | |
| 35 | ABBV | Abbvie Inc | Stock-Healthcare | 1.05% | -0.05% | +19.80% | |
| 36 | AAOI | Applied Optoelectronics Inc | Stock-Tech | 0.99% | -0.99% | EXIT | |
| 37 | ELVN | Enliven Therapeutics Inc | Stock-Other | 0.95% | -0.20% | -32.41% | |
| 38 | MRK | Merck & Co. Inc. | Stock-Healthcare | 0.93% | +0.05% | — | |
| 39 | VOR | Vor Biopharma Inc | Stock-Other | 0.91% | +0.09% | -21.56% | |
| 40 | ACAD | Acadia Pharmaceuticals Inc | Stock-Healthcare | 0.91% | +0.27% | +20.73% | |
| 41 | NVS | Novartis Ag-sponsored Adr | Stock-Healthcare | 0.90% | +0.12% | — | |
| 42 | ELDN | Eledon Pharmaceuticals Inc | Stock-Other | 0.87% | -0.26% | -16.88% | |
| 43 | ENPH | Enphase Energy Inc | Stock-Tech | 0.86% | -0.86% | EXIT | |
| 44 | RVMD | Revolution Medicines Inc | Stock-Healthcare | 0.85% | -0.30% | +4.97% | |
| 45 | PFE | Pfizer Inc | Stock-Healthcare | 0.83% | +0.07% | +116.28% | |
| 46 | BHVN | Biohaven Ltd. | Stock-Other | 0.80% | -0.48% | — | |
| 47 | FBRX | Forte Biosciences Inc | Stock-Other | 0.76% | -0.07% | -0.48% | |
| 48 | HELP | Cybin Inc | Stock-Other | 0.75% | +0.65% | +19.56% | |
| 49 | MDGL | Madrigal Pharmaceuticals Inc | Stock-Healthcare | 0.75% | +0.47% | +173.94% | |
| 50 | SRRK | Scholar Rock Holding CORP | Stock-Other | 0.74% | -0.06% | -40.44% |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | MLYS | Mineralys Therapeutics Inc | +2.6% | +198.43% | Add |
| 2 | XBI | Ss Spdr S&p Biotech ETF | +2.4% | +185.71% | Add |
| 3 | CYTK | Cytokinetics Inc | +2% | +226.13% | Add |
| 4 | BBIO | Bridgebio Pharma Inc | +1.3% | +127.61% | Add |
| 5 | TSEM | Tower Semiconductor Ltd. | +1.3% | +18.95% | Add |
| 6 | NVMI | Nova Ltd. | +0.6% | +11.54% | Add |
| 7 | PMN | Promis Neurosciences Inc | +0.6% | +2657.61% | Add |
| 8 | MAZE | Maze Therapeutics Inc | +0.5% | +216.44% | Add |
| 9 | CAMT | Camtek Ltd. | +0.5% | +34.23% | Add |
| 10 | PFE | Pfizer Inc | +0.4% | +116.28% | Add |
| 11 | PALI | Palisade Bio Inc | +0.4% | +841.59% | Add |
| 12 | MDGL | Madrigal Pharmaceuticals Inc | +0.4% | +173.94% | Add |
| 13 | ELVN | Enliven Therapeutics Inc | +0.3% | -32.41% | Trim |
| 14 | ELDN | Eledon Pharmaceuticals Inc | +0.3% | -16.88% | Trim |
| 15 | PRLD | Prelude Therapeutics Inc | +0.2% | +354.85% | Add |
| 16 | TNGX | Tango Therapeutics Inc | +0.2% | -36.91% | Trim |
| 17 | SEDG 2.25 07-01-29Bond | Solar Edge Technologies | +0.2% | — | Unchanged |
| 18 | APLSUSD | Apellis Pharmaceuticals Inc | +0.2% | -14.36% | Trim |
| 19 | STTK | Shattuck Labs Inc | +0.2% | +43.84% | Add |
| 20 | IBIT | Ishares Bitcoin Trust ETF | +0.1% | +97.99% | Add |
| 21 | BCRX | Biocryst Pharmaceuticals Inc | +0.1% | +3.41% | Add |
| 22 | RVMD | Revolution Medicines Inc | 0% | +4.97% | Add |
| 23 | VYGR | Voyager Therapeutics Inc | 0% | +38.26% | Add |
| 24 | HOWL | Werewolf Therapeutics Inc | — | — | Unchanged |
| 25 | SKYE | Skye Bioscience Inc | — | +41.76% | Add |
| 26 | BMY | Bristol-myers Squibb Co | 0% | — | Unchanged |
| 27 | APRE | Aprea Therapeutics Inc | 0% | — | Unchanged |
| 28 | CTNM | Contineum Therapeutics Inc-a | 0% | — | Unchanged |
| 29 | CLDX | Celldex Therapeutics Inc | 0% | +1.59% | Add |
| 30 | CRVS | Corvus Pharmaceuticals Inc | 0% | -39.18% | Trim |
| 31 | AMGN | Amgen Inc | -0.1% | — | Unchanged |
| 32 | COGT | Cogent Biosciences Inc | -0.1% | +10.00% | Add |
| 33 | MRK | Merck & Co. Inc. | -0.1% | — | Unchanged |
| 34 | SLNOEUR | Soleno Therapeutics Inc | -0.1% | +58.66% | Add |
| 35 | ABBV | Abbvie Inc | -0.1% | +19.80% | Add |
| 36 | GSK | Gsk Plc-spon Adr | -0.1% | — | Unchanged |
| 37 | NVS | Novartis Ag-sponsored Adr | -0.1% | — | Unchanged |
| 38 | TENX | Tenax Therapeutics Inc | -0.1% | -28.45% | Trim |
| 39 | ✓ | Mediwound LTD | -0.1% | +18.60% | Add |
| 40 | ZIM | ZIM Integrated Shipping Services Ltd. | -0.1% | -22.10% | Trim |
| 41 | VOR | Vor Biopharma Inc | -0.1% | -21.56% | Trim |
| 42 | TLT | Ishares 20+ Year Treasury Bd | -0.1% | — | Unchanged |
| 43 | ASND | Ascendis Pharma A/S | -0.2% | -27.27% | Trim |
| 44 | GPCR | Structure Therapeutics Inc | -0.2% | +23.90% | Add |
| 45 | SNY | Sanofi-adr | -0.2% | +12.53% | Add |
| 46 | ACAD | Acadia Pharmaceuticals Inc | -0.2% | +20.73% | Add |
| 47 | RARE | Ultragenyx Pharmaceutical In | -0.2% | +24.39% | Add |
| 48 | KURA | Kura Oncology Inc | -0.2% | — | Unchanged |
| 49 | VSTM | Verastem Inc | -0.2% | — | Unchanged |
| 50 | ACOG | Alpha Cognition Inc | -0.2% | — | Unchanged |
According to official SEC Form 13F filings, Sphera Funds Management LTD. reported a total U.S. public equity portfolio value of $766.5M across 95 disclosed positions in Q1 2026.
Expert Analysis & Guides for Tracking Wall Street Smart Money Movements
Learn how SEC Form 13F filings work, the $100M threshold, 45-day reporting lag, and how to track top hedge fund holdings.
In terms of portfolio concentration, the top 5 core holdings (including MLYS, TEVA, TSEM) accounted for 18.9% of total reported equity market value during Q1 2026.
Top New Position Initiated
AZN
市值: $12.3M
Top Position Liquidated / Trimmed
AZNN
前期市值: $12.4M
During Q1 2026, Sphera Funds Management LTD.'s top holdings by market value included MLYS (5.8%)、TEVA (5.4%)、TSEM (4.1%). The largest single position, MLYS, represented 5.8% of total portfolio value.
In Q1 2026, Sphera Funds Management LTD. made 104 total portfolio adjustments, initiating 20 new buys, adding to 32 positions, trimming 29 holdings, and fully liquidating 23 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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