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CIK: 0001496201
Total reported value
$766.5M
$766.5M
105 檔
13.9%
During the Q3 2025 filing period, Sphera Funds Management LTD. (CIK: 0001496201) submitted its Form 13F report to the U.S. SEC, disclosing a tracked public equity portfolio valued at $766.5M across 105 reported positions.
In Q3 2025, Sphera Funds Management LTD. adopted a defensive or profit-taking posture, trimming 48 positions and completely liquidating 40 holdings to manage risk exposure.
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | TEVA | Teva Pharmaceutical-sp Adr | Stock-Healthcare | 6.42% | +1.19% | -7.03% | |
| 2 | NICE | Nice LTD - Spon Adr | Stock-Tech | 4.81% | -0.10% | EXIT | |
| 3 | TSEM | Tower Semiconductor Ltd. | Stock-Tech | 4.76% | -0.38% | +17.78% | |
| 4 | CDTX | Cidara Therapeutics Inc | Stock-Other | 3.55% | — | +27.35% | |
| 5 | ✓ | Merus N V | Stock-Other | 2.98% | — | — | |
| 6 | NVMI | Nova Ltd. | Stock-Other | 2.96% | -1.90% | -42.12% | |
| 7 | QQQ | Invesco Qqq Trust Series 1 | ETF-Tech | 2.91% | — | — | |
| 8 | BIIB | Biogen Inc | Stock-Healthcare | 2.44% | +2.85% | — | |
| 9 | RARE | Ultragenyx Pharmaceutical In | Stock-Other | 2.24% | -0.13% | +25.61% | |
| 10 | AZNN | Astrazeneca Plc-spons Adr | Stock-Other | 2.19% | — | — | |
| 11 | SNY | Sanofi-adr | Stock-Healthcare | 2.19% | -0.56% | — | |
| 12 | CYTK | Cytokinetics Inc | Stock-Healthcare | 1.87% | +0.43% | -50.56% | |
| 13 | BBIO | Bridgebio Pharma Inc | Stock-Healthcare | 1.87% | -0.51% | +24.62% | |
| 14 | MLYS | Mineralys Therapeutics Inc | Stock-Other | 1.76% | -0.59% | -54.28% | |
| 15 | AM6 | Amicus Therapeutics Inc | Stock-Other | 1.65% | -1.39% | EXIT | |
| 16 | LLY | Eli Lilly & Co | Stock-Healthcare | 1.62% | -0.06% | -13.00% | |
| 17 | JNJ | Johnson & Johnson | Stock-Healthcare | 1.60% | -0.16% | — | |
| 18 | FBRX | Forte Biosciences Inc | Stock-Other | 1.50% | -0.07% | -4.20% | |
| 19 | TRVI | Trevi Therapeutics Inc | Stock-Other | 1.49% | +0.12% | -3.35% | |
| 20 | GPCR | Structure Therapeutics Inc | Stock-Other | 1.32% | -0.19% | +133.43% | |
| 21 | SNDX | Syndax Pharmaceuticals Inc | Stock-Other | 1.26% | +0.20% | -75.33% | |
| 22 | NVO | Novo-nordisk A/s-spons Adr | Stock-Healthcare | 1.24% | +0.05% | — | |
| 23 | ABBV | Abbvie Inc | Stock-Healthcare | 1.23% | -0.05% | — | |
| 24 | QURE | uniQure N.V. | Stock-Other | 1.23% | — | — | |
| 25 | PRAX | Praxis Precision Medicines I | Stock-Other | 1.21% | +0.55% | NEW | |
| 26 | CLBT | Cellebrite DI Ltd. | Stock-Other | 1.17% | -1.38% | EXIT | |
| 27 | ANNX | Annexon Inc | Stock-Other | 1.15% | — | +1.70% | |
| 28 | DYN | Dyne Therapeutics Inc | Stock-Other | 1.14% | +0.12% | +92.63% | |
| 29 | CLDX | Celldex Therapeutics Inc | Stock-Other | 1.13% | -0.06% | -50.48% | |
| 30 | SEDG 2.25 07-01-29Bond | Solar Edge Technologies | Bond | 1.12% | -0.09% | — | |
| 31 | GSK | Gsk Plc-spon Adr | Stock-Healthcare | 1.11% | -0.37% | — | |
| 32 | SEDG | Solaredge Technologies Inc | Stock-Tech | 1.10% | -0.43% | EXIT | |
| 33 | ORIC | Oric Pharmaceuticals Inc | Stock-Other | 1.09% | +0.13% | +9.37% | |
| 34 | ✓ | Immatics NV | Stock-Other | 1.05% | -0.14% | — | |
| 35 | SVRA | Savara Inc | Stock-Other | 1.02% | -0.03% | +3.06% | |
| 36 | NVS | Novartis Ag-sponsored Adr | Stock-Healthcare | 1.00% | +0.12% | — | |
| 37 | RAPP | Rapport Therapeutics Inc | Stock-Other | 0.99% | — | — | |
| 38 | VRNS | Varonis Systems Inc | Stock-Tech | 0.90% | — | — | |
| 39 | TLT | Ishares 20+ Year Treasury Bd | ETF-Gov Bonds | 0.89% | -0.12% | — | |
| 40 | IMVT | Immunovant Inc | Stock-Other | 0.87% | — | — | |
| 41 | MRK | Merck & Co. Inc. | Stock-Healthcare | 0.86% | +0.05% | — | |
| 42 | MAZE | Maze Therapeutics Inc | Stock-Other | 0.84% | +0.55% | -56.70% | |
| 43 | ELDN | Eledon Pharmaceuticals Inc | Stock-Other | 0.81% | -0.26% | -25.65% | |
| 44 | ✓ | Engene Holdings Inc | Stock-Other | 0.73% | — | — | |
| 45 | ESLT | Elbit Systems Ltd. | Stock-Industrials | 0.72% | — | +12.33% | |
| 46 | RZLT | Rezolute Inc | Stock-Other | 0.72% | — | -51.57% | |
| 47 | ELVN | Enliven Therapeutics Inc | Stock-Other | 0.72% | -0.20% | +29.76% | |
| 48 | ✓ | Mediwound LTD | Stock-Other | 0.70% | -0.18% | — | |
| 49 | ACAD | Acadia Pharmaceuticals Inc | Stock-Healthcare | 0.67% | +0.27% | -14.87% | |
| 50 | CAMT | Camtek Ltd. | Stock-Other | 0.64% | -1.28% | EXIT |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | TSEM | Tower Semiconductor Ltd. | +4.3% | +17.78% | Add |
| 2 | NICE | Nice LTD - Spon Adr | +3.6% | — | Add |
| 3 | CDTX | Cidara Therapeutics Inc | +3.5% | +27.35% | Add |
| 4 | ✓ | Merus N V | +2% | — | Add |
| 5 | BIIB | Biogen Inc | +1.7% | — | Add |
| 6 | GPCR | Structure Therapeutics Inc | +1% | +133.43% | Add |
| 7 | TEVA | Teva Pharmaceutical-sp Adr | +0.9% | -7.03% | Trim |
| 8 | ORIC | Oric Pharmaceuticals Inc | +0.8% | +9.37% | Add |
| 9 | CYTK | Cytokinetics Inc | +0.5% | -50.56% | Add |
| 10 | CRVS | Corvus Pharmaceuticals Inc | +0.5% | +122.68% | Add |
| 11 | ANNX | Annexon Inc | +0.4% | +1.70% | Add |
| 12 | DYN | Dyne Therapeutics Inc | +0.4% | +92.63% | Add |
| 13 | CAMT | Camtek Ltd. | +0.3% | -9.16% | Add |
| 14 | ELVN | Enliven Therapeutics Inc | +0.2% | +29.76% | Add |
| 15 | SVRA | Savara Inc | +0.2% | +3.06% | Add |
| 16 | IBIT | Ishares Bitcoin Trust ETF | +0.2% | — | Add |
| 17 | JSPR | Jasper Therapeutics Inc | +0.2% | +4190.57% | Add |
| 18 | ✓ | Engene Holdings Inc | +0.2% | — | Trim |
| 19 | CEVA | Ceva Inc | +0.2% | +65.75% | Add |
| 20 | CATBUSD | Astria Therapeutics Inc | +0.2% | -2.40% | Add |
| 21 | CATX | Perspective Therapeutics Inc | +0.1% | +64.44% | Add |
| 22 | HOWL | Werewolf Therapeutics Inc | +0.1% | — | Unchanged |
| 23 | CLYM | Climb Bio Inc | +0.1% | +107.23% | Add |
| 24 | IMVT | Immunovant Inc | +0.1% | — | Add |
| 25 | ✓ | Immatics NV | +0.1% | — | Trim |
| 26 | MLYS | Mineralys Therapeutics Inc | +0.1% | -54.28% | Trim |
| 27 | VTYXUSD | Ventyx Biosciences Inc | 0% | -20.82% | Trim |
| 28 | AVGO | Broadcom Inc | 0% | — | Trim |
| 29 | RZLT | Rezolute Inc | — | -51.57% | Trim |
| 30 | LRMR | Larimar Therapeutics Inc | — | +32.42% | Trim |
| 31 | APLT | Applied Therapeutics Inc | — | — | Unchanged |
| 32 | OKUR | Onkure Therapeutics Inc-a | 0% | — | Trim |
| 33 | GSK | Gsk Plc-spon Adr | -0.1% | — | Trim |
| 34 | SEDG | Solaredge Technologies Inc | -0.1% | +10.16% | Trim |
| 35 | APRE | Aprea Therapeutics Inc | -0.1% | — | Unchanged |
| 36 | KURA | Kura Oncology Inc | -0.1% | +4.25% | Trim |
| 37 | MAZE | Maze Therapeutics Inc | -0.1% | -56.70% | Trim |
| 38 | PFE | Pfizer Inc | -0.1% | — | Trim |
| 39 | BMY | Bristol-myers Squibb Co | -0.1% | — | Trim |
| 40 | SKYE | Skye Bioscience Inc | -0.1% | -11.05% | Trim |
| 41 | AMGN | Amgen Inc | -0.2% | — | Trim |
| 42 | COGT | Cogent Biosciences Inc | -0.2% | -71.33% | Trim |
| 43 | ACOG | Alpha Cognition Inc | -0.2% | -10.06% | Trim |
| 44 | ABBV | Abbvie Inc | -0.2% | — | Trim |
| 45 | BHVN | Biohaven Ltd. | -0.3% | -37.30% | Trim |
| 46 | PMNEUR | Promis Neurosciences Inc | -0.3% | -84.46% | Trim |
| 47 | NVS | Novartis Ag-sponsored Adr | -0.3% | — | Trim |
| 48 | HELP | Cybin Inc | -0.3% | -7.01% | Trim |
| 49 | TVTX | Travere Therapeutics Inc | -0.3% | -69.64% | Trim |
| 50 | JANX | Janux Therapeutics Inc | -0.3% | — | Trim |
According to official SEC Form 13F filings, Sphera Funds Management LTD. reported a total U.S. public equity portfolio value of $766.5M across 105 disclosed positions in Q3 2025.
Expert Analysis & Guides for Tracking Wall Street Smart Money Movements
Learn how SEC Form 13F filings work, the $100M threshold, 45-day reporting lag, and how to track top hedge fund holdings.
In terms of portfolio concentration, the top 5 core holdings (including TEVA, NICE, TSEM) accounted for 13.9% of total reported equity market value during Q3 2025.
Top New Position Initiated
QQQ
市值: $13.8M
Top Position Liquidated / Trimmed
ORA 2.5 07-15-27 SEPT
前期市值: $5.2M
During Q3 2025, Sphera Funds Management LTD.'s top holdings by market value included TEVA (6.4%)、NICE (4.8%)、TSEM (4.8%). The largest single position, TEVA, represented 6.4% of total portfolio value.
In Q3 2025, Sphera Funds Management LTD. made 142 total portfolio adjustments, initiating 32 new buys, adding to 22 positions, trimming 48 holdings, and fully liquidating 40 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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