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CIK: 0001055951
Total reported value
$5.4B
$5.4B
110 檔
25.9%
According to the latest 13F quarterly dataset, Orbimed Advisors LLC managed an equity portfolio of $5.4B at the end of Q2 2024, spanning 110 distinct U.S. exchange-listed positions.
Orbimed Advisors LLC executed strategic sector rebalancing during Q2 2024, establishing 5 new positions while fully exiting 7 holdings and trimming 12 positions.
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SVA | Sinovac Biotech Ltd. | Stock-Other | 6.71% | +3.06% | — | |
| 2 | LLY | Eli Lilly & Co | Stock-Healthcare | 6.04% | +1.30% | -6.43% | |
| 3 | EWTX | Edgewise Therapeutics Inc | Stock-Other | 5.34% | +1.73% | — | |
| 4 | BSX | Boston Scientific CORP | Stock-Healthcare | 4.98% | -1.88% | — | |
| 5 | ISRG | Intuitive Surgical Inc | Stock-Healthcare | 4.33% | -0.80% | — | |
| 6 | BIIB | Biogen Inc | Stock-Healthcare | 4.12% | +0.02% | — | |
| 7 | ELVN | Enliven Therapeutics Inc | Stock-Other | 3.67% | +0.02% | -11.54% | |
| 8 | MRK | Merck & Co. Inc. | Stock-Healthcare | 3.22% | -0.05% | — | |
| 9 | THC | Tenet Healthcare CORP | Stock-Healthcare | 3.08% | — | — | |
| 10 | JANX | Janux Therapeutics Inc | Stock-Other | 2.46% | -0.13% | -30.31% | |
| 11 | IONS | Ionis Pharmaceuticals Inc | Stock-Healthcare | 2.23% | — | +17.85% | |
| 12 | SRPT | Sarepta Therapeutics Inc | Stock-Healthcare | 2.17% | — | -0.22% | |
| 13 | SYK | Stryker CORP | Stock-Healthcare | 1.81% | -0.30% | — | |
| 14 | ELV | Elevance Health Inc | Stock-Healthcare | 1.80% | +0.21% | — | |
| 15 | ARGX | Argenx Se - Adr | Stock-Healthcare | 1.78% | -0.44% | +37.93% | |
| 16 | IRON | Disc Medicine Inc | Stock-Other | 1.59% | -0.91% | +4.90% | |
| 17 | SPRY | Ars Pharmaceuticals Inc | Stock-Other | 1.55% | -0.12% | — | |
| 18 | ✓ | Third Harmonic Bio Inc | Stock-Other | 1.48% | — | — | |
| 19 | NTRA | Natera Inc | Stock-Healthcare | 1.47% | +0.26% | -23.56% | |
| 20 | TMO | Thermo Fisher Scientific Inc | Stock-Healthcare | 1.44% | +0.38% | — | |
| 21 | VRTX | Vertex Pharmaceuticals Inc | Stock-Healthcare | 1.40% | — | +23.06% | |
| 22 | SWTXUSD | Springworks Therapeutics Inc | Stock-Other | 1.27% | — | — | |
| 23 | NBIX | Neurocrine Biosciences Inc | Stock-Healthcare | 1.22% | — | +5.93% | |
| 24 | ALNY | Alnylam Pharmaceuticals Inc | Stock-Healthcare | 1.20% | -0.71% | — | |
| 25 | PCVX | Vaxcyte Inc | Stock-Other | 1.19% | — | -25.35% | |
| 26 | KROS | Keros Therapeutics Inc | Stock-Other | 1.14% | -0.02% | — | |
| 27 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 1.13% | -0.04% | -7.52% | |
| 28 | UNH | Unitedhealth Group Inc | Stock-Healthcare | 1.13% | +1.33% | NEW | |
| 29 | AVBP | Arrivent Biopharma Inc | Stock-Other | 1.11% | +0.53% | — | |
| 30 | ICLR | ICON Public Limited Company | Stock-Healthcare | 1.08% | — | — | |
| 31 | 430 | Terns Pharmaceuticals Inc | Stock-Other | 1.02% | — | — | |
| 32 | APLSUSD | Apellis Pharmaceuticals Inc | Stock-Other | 0.99% | — | -10.02% | |
| 33 | EVH | Evolent Health Inc - A | Stock-Other | 0.98% | — | — | |
| 34 | XTNT | Xtant Medical Holdings Inc | Stock-Other | 0.91% | — | — | |
| 35 | SIBN | Si-bone Inc | Stock-Other | 0.89% | — | +1.62% | |
| 36 | CYTK | Cytokinetics Inc | Stock-Healthcare | 0.87% | +0.04% | NEW | |
| 37 | AMGN | Amgen Inc | Stock-Healthcare | 0.83% | -0.29% | EXIT | |
| 38 | PRLD | Prelude Therapeutics Inc | Stock-Other | 0.82% | +0.60% | — | |
| 39 | VRNA | Verona Pharma PLC - Adr | Stock-Other | 0.82% | — | -15.78% | |
| 40 | QTTB | Q32 Bio Inc | Stock-Other | 0.80% | +0.68% | — | |
| 41 | ITGR | Integer Holdings CORP | Stock-Healthcare | 0.80% | — | — | |
| 42 | GERN | Geron CORP | Stock-Other | 0.80% | — | -26.09% | |
| 43 | SNDX | Syndax Pharmaceuticals Inc | Stock-Other | 0.78% | +0.17% | +10.08% | |
| 44 | XENE | Xenon Pharmaceuticals Inc | Stock-Other | 0.66% | -0.26% | +56.79% | |
| 45 | DXCM | Dexcom Inc | Stock-Healthcare | 0.65% | — | +106.63% | |
| 46 | ✓ | Ikena Oncology Inc | Stock-Other | 0.63% | -0.45% | EXIT | |
| 47 | RYTM | Rhythm Pharmaceuticals Inc | Stock-Other | 0.57% | +0.11% | — | |
| 48 | RNAGBP | Avidity Biosciences Inc | Stock-Other | 0.57% | — | -28.93% | |
| 49 | EXK | Exact Sciences CORP | Stock-Materials | 0.56% | — | +378.93% | |
| 50 | NPCE | Neuropace Inc | Stock-Other | 0.51% | -0.11% | -14.93% |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ALNY | Alnylam Pharmaceuticals Inc | +1.2% | NEW | New buy |
| 2 | LLY | Eli Lilly & Co | +0.9% | -6.43% | Trim |
| 3 | BSX | Boston Scientific CORP | +0.9% | — | Unchanged |
| 4 | THC | Tenet Healthcare CORP | +0.8% | — | Unchanged |
| 5 | ITGR | Integer Holdings CORP | +0.8% | NEW | New buy |
| 6 | ELVN | Enliven Therapeutics Inc | +0.8% | -11.54% | Trim |
| 7 | ISRG | Intuitive Surgical Inc | +0.7% | — | Unchanged |
| 8 | ARGX | Argenx Se - Adr | +0.7% | +37.93% | Add |
| 9 | IONS | Ionis Pharmaceuticals Inc | +0.6% | +17.85% | Add |
| 10 | BIIB | Biogen Inc | +0.6% | — | Unchanged |
| 11 | SRPT | Sarepta Therapeutics Inc | +0.5% | -0.22% | Trim |
| 12 | AMGN | Amgen Inc | +0.5% | +112.78% | Add |
| 13 | UNH | Unitedhealth Group Inc | +0.5% | +60.00% | Add |
| 14 | ✓ | Third Harmonic Bio Inc | +0.5% | — | Unchanged |
| 15 | VRTX | Vertex Pharmaceuticals Inc | +0.5% | +23.06% | Add |
| 16 | EXK | Exact Sciences CORP | +0.4% | +378.93% | Add |
| 17 | VIR | Vir Biotechnology Inc | +0.3% | +262.52% | Add |
| 18 | DXCM | Dexcom Inc | +0.3% | +106.63% | Add |
| 19 | ✓ | Adc Therapeutics SA | +0.3% | NEW | New buy |
| 20 | ✓ | Merus N V | +0.2% | NEW | New buy |
| 21 | CGEM | Cullinan Therapeutics Inc | +0.2% | +121.72% | Add |
| 22 | SOLV | Solventum CORP | +0.2% | NEW | New buy |
| 23 | MRK | Merck & Co. Inc. | 0% | — | Unchanged |
| 24 | PRLD | Prelude Therapeutics Inc | -0.1% | — | Unchanged |
| 25 | PCVX | Vaxcyte Inc | -0.1% | -25.35% | Trim |
| 26 | SIBN | Si-bone Inc | -0.1% | +1.62% | Add |
| 27 | SPRY | Ars Pharmaceuticals Inc | -0.2% | — | Unchanged |
| 28 | VRNA | Verona Pharma PLC - Adr | -0.2% | -15.78% | Trim |
| 29 | VTYXUSD | Ventyx Biosciences Inc | -0.2% | EXIT | Sold out |
| 30 | TORCEUR | Adicet Bio Inc | -0.2% | — | Unchanged |
| 31 | VSTM | Verastem Inc | -0.2% | — | Unchanged |
| 32 | SWTXUSD | Springworks Therapeutics Inc | -0.3% | — | Unchanged |
| 33 | ✓ | -0.3% | EXIT | Sold out | |
| 34 | ALXO | Alx Oncology Holdings Inc | -0.3% | -30.30% | Trim |
| 35 | IRON | Disc Medicine Inc | -0.4% | +4.90% | Add |
| 36 | CMPX | Compass Therapeutics Inc | -0.4% | — | Unchanged |
| 37 | KNTEUSD | Kinnate Biopharma Inc | -0.4% | EXIT | Sold out |
| 38 | ARWR | Arrowhead Pharmaceuticals In | -0.4% | EXIT | Sold out |
| 39 | KROS | Keros Therapeutics Inc | -0.4% | — | Unchanged |
| 40 | NPCE | Neuropace Inc | -0.5% | -14.93% | Trim |
| 41 | JANX | Janux Therapeutics Inc | -0.5% | -30.31% | Trim |
| 42 | PRAX | Praxis Precision Medicines I | -0.5% | EXIT | Sold out |
| 43 | APLSUSD | Apellis Pharmaceuticals Inc | -0.6% | -10.02% | Trim |
| 44 | EVH | Evolent Health Inc - A | -0.6% | — | Unchanged |
| 45 | APGE | Apogee Therapeutics Inc | -0.6% | -47.26% | Trim |
| 46 | XTNT | Xtant Medical Holdings Inc | -0.7% | — | Unchanged |
| 47 | ESPR | Esperion Therapeutics Inc | -0.7% | EXIT | Sold out |
| 48 | SRRK | Scholar Rock Holding CORP | -1% | -69.94% | Trim |
| 49 | NVLSEUR | Alpine Immune Sciences Inc | -2% | EXIT | Sold out |
| 50 | BMRN | Biomarin Pharmaceutical Inc | -2% | -97.96% | Trim |
According to official SEC Form 13F filings, Orbimed Advisors LLC reported a total U.S. public equity portfolio value of $5.4B across 110 disclosed positions in Q2 2024.
During Q2 2024, Orbimed Advisors LLC's top holdings by market value included SVA (6.7%)、LLY (6.0%)、EWTX (5.3%). The largest single position, SVA, represented 6.7% of total portfolio value.
Expert Analysis & Guides for Tracking Wall Street Smart Money Movements
Learn how SEC Form 13F filings work, the $100M threshold, 45-day reporting lag, and how to track top hedge fund holdings.
In terms of portfolio concentration, the top 5 core holdings (including SVA, LLY, EWTX) accounted for 25.9% of total reported equity market value during Q2 2024.
Top New Position Initiated
ALNY
市值: $60.8M
Top Position Liquidated / Trimmed
NVLSEUR
前期市值: $106.3M
In Q2 2024, Orbimed Advisors LLC made 35 total portfolio adjustments, initiating 5 new buys, adding to 11 positions, trimming 12 holdings, and fully liquidating 7 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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